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  1. Article ; Online: A contemporary and inflammatory triangle at the mucosa: HIV, antibodies and bacterial STIs.

    Yamamoto, Hiroyuki

    AIDS (London, England)

    2023  Volume 37, Issue 5, Page(s) 841–843

    MeSH term(s) Humans ; HIV Infections ; Sexually Transmitted Diseases ; Sexual Behavior ; Antibodies ; Mucous Membrane
    Chemical Substances Antibodies
    Language English
    Publishing date 2023-03-14
    Publishing country England
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 639076-6
    ISSN 1473-5571 ; 0269-9370 ; 1350-2840
    ISSN (online) 1473-5571
    ISSN 0269-9370 ; 1350-2840
    DOI 10.1097/QAD.0000000000003498
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2228: Show issues Location:
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  2. Article: [In vivo protective mechanisms of neutralizing antibodies against simian immunodeficiency virus replicatio].

    Yamamoto, Hiroyuki

    Uirusu

    2022  Volume 71, Issue 1, Page(s) 87–96

    Abstract: Identifying protective adaptive immune responses against human immunodeficiency virus type 1 (HIV-1), mainly comprising CD8+ cytotoxic T lymphocyte (CTL) and neutralizing antibody (NAb) responses, is crucial for understanding in vivo mechanisms of viral ... ...

    Abstract Identifying protective adaptive immune responses against human immunodeficiency virus type 1 (HIV-1), mainly comprising CD8+ cytotoxic T lymphocyte (CTL) and neutralizing antibody (NAb) responses, is crucial for understanding in vivo mechanisms of viral persistence and developing prophylactic/intervention strategies. In HIV-1 and pathogenic simian immunodeficiency virus (SIV) infections, CTL responses play the canonical role in primary viral replication control, whereas NAb responses are impaired. This NAb impairment in early infection conversely highlights the necessity of elucidating anti-HIV/SIV antibody defense/induction mechanisms, and one approach to analyze the impact of NAbs on HIV/SIV infection is passive immunization. We have analyzed a simian AIDS model of highly pathogenic SIVmac239-infected rhesus macaques, and characterized that a single acute-phase passive infusion of SIV-specific polyclonal NAbs drives a synergistic qualitative boosting of virus-specific T-cell responses, resulting in sustained SIV replication control. This in vivo functional augmentation of virus-specific T cells by NAbs in the SIV model provides insights into the design of protective immunity against HIV-1 infection.
    MeSH term(s) Animals ; Antibodies, Neutralizing ; Antibodies, Viral ; HIV-1 ; Immunization, Passive ; Macaca mulatta ; Simian Acquired Immunodeficiency Syndrome/prevention & control ; Simian Immunodeficiency Virus
    Chemical Substances Antibodies, Neutralizing ; Antibodies, Viral
    Language Japanese
    Publishing date 2022-03-25
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 603272-2
    ISSN 0042-6857
    ISSN 0042-6857
    DOI 10.2222/jsv.71.87
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 266: Show issues Location:
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  3. Book ; Online: Chapter 7: 'Our People'

    Yamamoto, Hiroyuki

    2012  

    Abstract: This book discusses contemporary film in all the main countries of Southeast Asia, and the social practices and ideologies which films either represent or oppose. It shows how film acquires signification through cultural interpretation, and how film also ...

    Abstract This book discusses contemporary film in all the main countries of Southeast Asia, and the social practices and ideologies which films either represent or oppose. It shows how film acquires signification through cultural interpretation, and how film also serves as a site of contestations between social and political agents seeking to promote, challenge, or erase certain meanings, messages or ideas from public circulation. A unique feature of the book is that it focuses as much on films as it does on the societies from which these films emerge: it considers the reasons for film-makers taking the positions they take; the positions and counter-positions taken; the response of different communities; and the extent to which these interventions are connected to global flows of culture and capital
    Keywords Communities. Classes. Races ; Science (General) ; Motion pictures ; Communication. Mass media
    Size 1 electronic resource (18 pages)
    Publisher Taylor and Francis
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020480732
    ISBN 9780415617635 ; 9780415626187 ; 0415617634 ; 0415626188
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  4. Article ; Online: Multiset partial least squares with rank order of groups for integrating multi-omics data

    Yamamoto, Hiroyuki

    bioRxiv

    Abstract: As more multi-omics data such as metabolome, proteome and transcriptome data are acquired, statistical analyses to integrate multi-omics data has been required. Multivariate analysis for integration of multi-omics data has been proposed such as multiset ... ...

    Abstract As more multi-omics data such as metabolome, proteome and transcriptome data are acquired, statistical analyses to integrate multi-omics data has been required. Multivariate analysis for integration of multi-omics data has been proposed such as multiset partial least squares (PLS). However, when we want to extract scores about the rank order of groups such as severity of disease as well as difference of groups, we could not always extract scores with rank order of groups by using multiset PLS. Therefore, we proposed multiset PLS with rank order of groups (multiset PLS-ROG) to integrate multiple omics dataset. We visualized multiple omics data by using multiset PLS-ROG in two studies of multi-omics and multi-organ derived metabolome data. After we visualize data and focus on a specific score with phenotype of interest, it is important to select compounds to identify biomarker candidates or make biological inferences. In ordinary principal component analysis (PCA) or PLS, we could select statistical significantly compounds correlated with PC or PLS score by using PC or PLS loadings. However, multiset PLS loading has not been used because its statistical property has not been clarified. Then, we clarified statistical property of multiset PLS and multiset PLS-ROG loading, and we could identify statistically significant compounds by using statistical hypothesis testing. We implemented multiset PLS-ROG to R loadings package, freely available in CRAN.
    Keywords covid19
    Language English
    Publishing date 2022-08-31
    Publisher Cold Spring Harbor Laboratory
    Document type Article ; Online
    DOI 10.1101/2022.08.30.505949
    Database COVID19

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  5. Article ; Online: The gastric double-stripe sign of chronic mesenteric ischemia: A case report.

    Yamamoto, Hiroyuki / Hashimoto, Toru

    Medicine

    2023  Volume 102, Issue 5, Page(s) e32842

    Abstract: Rationale: Atherosclerotic chronic mesenteric ischemia (CMI) is caused by stenosis or occlusion of mesenteric arteries and can progress to potentially life-threatening acute mesenteric ischemia if left untreated. However, correct diagnosis and timely ... ...

    Abstract Rationale: Atherosclerotic chronic mesenteric ischemia (CMI) is caused by stenosis or occlusion of mesenteric arteries and can progress to potentially life-threatening acute mesenteric ischemia if left untreated. However, correct diagnosis and timely treatment remain a challenge due to a lack of awareness, variable symptoms, and inconclusive diagnostic testing.
    Patient concerns: An 82-year-old man with multiple cardiovascular risk factors, including chronic kidney disease, presented with dyspnea, anorexia, and oliguria. Laboratory results revealed severe renal dysfunction (raised serum blood urea nitrogen of 83.8 mg/dL, serum creatinine levels of 8.20 mg/dL, and decreased estimated glomerular filtration rate of 5.5 mL/min/1.73 m 2 ), hypoalbuminemia, and moderate anemia. A provisional diagnosis of acute exacerbation of chronic kidney disease was made and the patient required tentative intermittent hemodialysis, received blood transfusions, and was eventually placed on maintenance hemodialysis. However, the patient's symptoms did not improve. Esophagogastroduodenoscopy (EGD) revealed longitudinal gastric ulcers on the anterior and posterior walls of the stomach, which were named "a gastric double-stripe sign" because the lesions corresponded to the watershed areas of the stomach. No Helicobacter pylori infection or malignancy was identified, and increasing the dose of lansoprazole had no beneficial effects. Doppler ultrasound revealed high peak systolic velocity (270 cm/s) of the celiac artery (CA), suggesting CA stenosis, which was confirmed by magnetic resonance angiography.
    Diagnosis: Final diagnosis of CMI was made based on patient's symptoms, EGD findings, Doppler ultrasound, and magnetic resonance angiography.
    Interventions: Endovascular revascularization for CA stenosis was performed.
    Outcomes: The patient obtained symptomatic relief concomitant with the resolution of the gastric ulcers. The post-procedural course of the patient was uneventful and he remained healthy at the 1-year follow-up.
    Lessons: This is the first case of CMI with EGD finding of a gastric double-stripe sign specific for gastric ischemia. This case highlights the clinical importance of this endoscopic finding in patients with suspected atherosclerotic CMI.
    MeSH term(s) Male ; Humans ; Aged, 80 and over ; Mesenteric Ischemia/therapy ; Stomach Ulcer/complications ; Constriction, Pathologic/complications ; Mesenteric Vascular Occlusion/etiology ; Chronic Disease ; Ischemia/etiology ; Atherosclerosis/complications ; Renal Insufficiency, Chronic/complications ; Mesenteric Artery, Superior ; Stents/adverse effects ; Treatment Outcome
    Language English
    Publishing date 2023-02-07
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000032842
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    Ua VI Zs.171: Show issues Location:
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  6. Article: Transient constrictive pericarditis following coxsackievirus A4 infection as a rare cause of acute mediastinitis: A case report.

    Yamamoto, Hiroyuki / Isogai, Jun

    Heliyon

    2023  Volume 9, Issue 9, Page(s) e19555

    Abstract: Background: Transient constrictive pericarditis (TCP) is a distinct constrictive pericarditis (CP) subtype characterized by acute pericardial inflammation and transient constrictive physiology. If left untreated, it may progress to irreversible CP ... ...

    Abstract Background: Transient constrictive pericarditis (TCP) is a distinct constrictive pericarditis (CP) subtype characterized by acute pericardial inflammation and transient constrictive physiology. If left untreated, it may progress to irreversible CP requiring pericardiectomy. However, making an early diagnosis of TCP remains difficult.
    Case presentation: A 51-year-old man presented with fever, chest pain, and dyspnea following preceding flu symptoms. An initial investigation suggested right-sided heart failure. Laboratory results revealed elevated inflammatory markers and hepatic enzyme levels. Echocardiography revealed pericardial effusion with a normal ejection fraction and diastolic ventricular septal bounce suggestive of pericardial constriction. Computed tomography suggested acute descending mediastinitis with pericarditis and pleuritis; however, detailed examinations ruled out this possibility. The constellation of increased serological inflammation, pericardial thickness/effusion, and constrictive physiology suggested TCP, confirmed by cardiac magnetic resonance (CMR) and hemodynamic studies. CMR also revealed coexistent myocarditis. After a thorough assessment for the cause of TCP, a viral etiology was suspected. Paired serology for virus antibody titers revealed a significant increase only in coxsackievirus A4 (CVA4) titers. With prompt anti-inflammatory treatment, the patient's pericardial structure and function and concomitant inflammation of the surrounding tissues were nearly completely recovered, leading to a final diagnosis of TCP caused by CVA4. The subsequent clinical course was uneventful without recurrence at the 1-year follow-up.
    Conclusions: Here we described the first case of TCP caused by CVA4 concurrent with mediastinitis, myocarditis, and pleuritis, all of which were successfully resolved with anti-inflammatory treatment. Acute mediastinitis secondary to TCP is rare. This case highlights the clinical importance of assessing pericardial diseases as a source of acute mediastinitis and considering CVA4 as an etiology of TCP. An evaluation including multimodal cardiac imaging and serology for virus antibody titers may be useful for an exploratory diagnosis of TCP in right-sided heart failure patients with pericardial effusion.
    Language English
    Publishing date 2023-08-30
    Publishing country England
    Document type Case Reports
    ZDB-ID 2835763-2
    ISSN 2405-8440
    ISSN 2405-8440
    DOI 10.1016/j.heliyon.2023.e19555
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  7. Article ; Online: Proximal migration of in-stent neoatherosclerosis debris following cutting balloon angioplasty leading to catastrophic no-flow phenomenon.

    Watanabe, Nobuhiro / Yamamoto, Hiroyuki / Takaya, Tomofumi

    Coronary artery disease

    2024  Volume 35, Issue 2, Page(s) 162–163

    MeSH term(s) Humans ; Angioplasty, Balloon, Coronary/adverse effects ; Angioplasty, Balloon/adverse effects ; Stents ; Treatment Outcome
    Language English
    Publishing date 2024-01-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 1047268-x
    ISSN 1473-5830 ; 0954-6928
    ISSN (online) 1473-5830
    ISSN 0954-6928
    DOI 10.1097/MCA.0000000000001310
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3039: Show issues Location:
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  8. Article ; Online: Entrapment of the Impella device by the guiding catheter: a cautionary pitfall of Impella-protected percutaneous coronary intervention.

    Yamamoto, Hiroyuki / Watanabe, Nobuhiro / Matsuo, Koki / Takaya, Tomofumi

    European heart journal. Case reports

    2024  Volume 8, Issue 3, Page(s) ytae096

    Language English
    Publishing date 2024-02-19
    Publishing country England
    Document type Case Reports
    ISSN 2514-2119
    ISSN (online) 2514-2119
    DOI 10.1093/ehjcr/ytae096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Descriptive analysis of long-term survival after aortic valve replacement for dialysis patients: importance of renal pathologies and age.

    Matsuura, Kaoru / Yamamoto, Hiroyuki / Matsumiya, Goro / Motomura, Noboru

    General thoracic and cardiovascular surgery

    2024  

    Abstract: Objectives: This study analyzed the long-term survival of dialysis patients undergoing AVR using the Japanese National Clinical Database with additional survival data.: Methods: De-novo AVR for dialysis-dependent patients between 2010 and 2012 who ... ...

    Abstract Objectives: This study analyzed the long-term survival of dialysis patients undergoing AVR using the Japanese National Clinical Database with additional survival data.
    Methods: De-novo AVR for dialysis-dependent patients between 2010 and 2012 who were registered in the Japan Cardiovascular Surgery Database were included. Concomitant aortic surgery and transcatheter aortic valve replacement were excluded. An additional questionnaire was sent to each hospital regarding the underlying kidney disease, the duration of dialysis initiation to the surgery, and clinical outcomes. The Kaplan-Meier survival curve was descriptively shown for all cohorts and each renal pathology. Furthermore, we compared the incidence of bioprosthetic valve failure in patients who were < 65 years old (group Y) and ≧65 years old (group O).
    Results: Of these 1529 patients, diabetic nephropathy was 517, chronic glomerulonephritis was 437, and renal sclerosis was 210, regarding renal pathology. 1, 3, and 5-year survival in each pathology was 78.4%, 58.6%, 45.9% in diabetic nephritis, 78.8%, 68.4%, 58.2% in chronic glomerulonephritis, 79.0%, 67.8%, 52.1% in renal sclerosis, and 74.4%, 62.6%, 49.2% in others. Active infectious endocarditis was more prevalent in group Y (O 2.7% vs. Y 9.6%). The incidence of bioprosthetic valve failure requiring re-hospitalization was too small to analyze. 1, 3, and 5-year survival was 76.0%, 63.4%, 49.2% in group O and 74.3%, 64.2%, and 47.7% in group Y.
    Conclusions: Long-term survival of AVR for dialysis-dependent was higher in patients with chronic glomerulonephritis and lower in patients with diabetic nephritis than in other pathologies.
    Language English
    Publishing date 2024-03-07
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2376888-5
    ISSN 1863-6713 ; 1863-6705
    ISSN (online) 1863-6713
    ISSN 1863-6705
    DOI 10.1007/s11748-024-02011-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book ; Online: Film in contemporary Southeast Asia : Cultural Interpretation and Social Intervention

    Lim, David C. L. / Yamamoto, Hiroyuki

    2012  

    Keywords Film, TV & radio ; Film ; Southeast Asia
    Size 1 electronic resource (226 pages)
    Publisher Taylor and Francis
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021031282
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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