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Article: Bywaters Lesions: A Rare Cutaneous Vasculitis in Rheumatoid Arthritis.

Yamamoto, Mari / Fujita, Yoshiro

2023 Volume 50, Issue 10, Page(s) 1353

MeSH term(s)	Humans ; Arthritis, Rheumatoid/complications ; Arthritis, Rheumatoid/drug therapy ; Skin Diseases, Vascular
Language	English
Publishing date	2023-06-01
Publishing country	Canada
Document type	Journal Article
ZDB-ID	194928-7
ISSN	1499-2752 ; 0315-162X
ISSN (online)	1499-2752
ISSN	0315-162X
DOI	10.3899/jrheum.2023-0169
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Article ; Online: Adult-onset transient pseudohypoaldosteronism secondary to obstructive nephropathy: a case report.

Yamamoto, Mari / Sakamoto, Fumitoshi / Ikai, Hiroki / Fujita, Yoshiro

International urology and nephrology

2024

Language	English
Publishing date	2024-02-20
Publishing country	Netherlands
Document type	Letter
ZDB-ID	204048-7
ISSN	1573-2584 ; 0301-1623 ; 0042-1162
ISSN (online)	1573-2584
ISSN	0301-1623 ; 0042-1162
DOI	10.1007/s11255-024-03975-0
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Article ; Online: Single-Nucleotide Polymorphism on Spermatogenesis Associated 16 Gene-Coding Region Affecting Bovine Leukemia Virus Proviral Load.

Mekata, Hirohisa / Yamamoto, Mari

Veterinary sciences

2022 Volume 9, Issue 6

Abstract: Bovine leukemia virus (BLV) is an etiological agent of malignant lymphoma in cattle and is endemic in many cattle-breeding countries. Thus, the development of cattle genetically resistant to BLV is desirable. The purpose of this study was to identify ... ...

Abstract	Bovine leukemia virus (BLV) is an etiological agent of malignant lymphoma in cattle and is endemic in many cattle-breeding countries. Thus, the development of cattle genetically resistant to BLV is desirable. The purpose of this study was to identify novel single-nucleotide polymorphisms (SNPs) related to resistance to BLV. A total of 146 DNA samples from cattle with high BLV proviral loads (PVLs) and 142 samples from cattle with low PVLs were used for a genome-wide association study (GWAS). For the verification of the GWAS results, an additional 1342 and 456 DNA samples from BLV-infected Japanese Black and Holstein cattle, respectively, were used for an SNP genotyping PCR to compare the genotypes for the identified SNPs and PVLs. An SNP located on the spermatogenesis associated 16 (SPATA16)-coding region on bovine chromosome 1 was found to exceed the moderate threshold (p < 1.0 × 10−5) in the Additive and Dominant models of the GWAS. The SNP genotyping PCR revealed that the median values of the PVL were 1278 copies/50 ng of genomic DNA for the major homozygous, 843 for the heterozygous, and 621 for the minor homozygous genotypes in the Japanese Black cattle (p < 0.0001). A similar tendency was also observed in the Holstein cattle. We found that cattle with the minor allele for this SNP showed 20−25% lower PVLs. Although the mechanisms through which this SNP impacts the PVL remain unknown, we found a novel SNP related to BLV resistance located on the SPATA16 gene-coding region on bovine chromosome 1.
Language	English
Publishing date	2022-06-06
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2768971-2
ISSN	2306-7381 ; 2306-7381
ISSN (online)	2306-7381
ISSN	2306-7381
DOI	10.3390/vetsci9060275
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Article: Single-Nucleotide Polymorphism on Spermatogenesis Associated 16 Gene-Coding Region Affecting Bovine Leukemia Virus Proviral Load

Mekata, Hirohisa / Yamamoto, Mari

Veterinary sciences. 2022 June 06, v. 9, no. 6

2022

Abstract	Bovine leukemia virus (BLV) is an etiological agent of malignant lymphoma in cattle and is endemic in many cattle-breeding countries. Thus, the development of cattle genetically resistant to BLV is desirable. The purpose of this study was to identify novel single-nucleotide polymorphisms (SNPs) related to resistance to BLV. A total of 146 DNA samples from cattle with high BLV proviral loads (PVLs) and 142 samples from cattle with low PVLs were used for a genome-wide association study (GWAS). For the verification of the GWAS results, an additional 1342 and 456 DNA samples from BLV-infected Japanese Black and Holstein cattle, respectively, were used for an SNP genotyping PCR to compare the genotypes for the identified SNPs and PVLs. An SNP located on the spermatogenesis associated 16 (SPATA16)-coding region on bovine chromosome 1 was found to exceed the moderate threshold (p < 1.0 × 10⁻⁵) in the Additive and Dominant models of the GWAS. The SNP genotyping PCR revealed that the median values of the PVL were 1278 copies/50 ng of genomic DNA for the major homozygous, 843 for the heterozygous, and 621 for the minor homozygous genotypes in the Japanese Black cattle (p < 0.0001). A similar tendency was also observed in the Holstein cattle. We found that cattle with the minor allele for this SNP showed 20–25% lower PVLs. Although the mechanisms through which this SNP impacts the PVL remain unknown, we found a novel SNP related to BLV resistance located on the SPATA16 gene-coding region on bovine chromosome 1.
Keywords	Bovine leukemia virus ; DNA ; Holstein ; Wagyu ; alleles ; cattle ; chromosomes ; etiological agents ; genome-wide association study ; genotyping ; heterozygosity ; homozygosity ; lymphoma ; single nucleotide polymorphism ; spermatogenesis
Language	English
Dates of publication	2022-0606
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article
ZDB-ID	2768971-2
ISSN	2306-7381
ISSN	2306-7381
DOI	10.3390/vetsci9060275
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Nanoporous silicon fiber networks in a composite anode for all-solid-state batteries with superior cycling performance.

Yamamoto, Mari / Takatsu, Mika / Okuno, Ryota / Kato, Atsutaka / Takahashi, Masanari

Scientific reports

2023 Volume 13, Issue 1, Page(s) 17051

Abstract: All-solid-state batteries comprising Si anodes are promising materials for energy storage in electronic vehicles because their energy density is approximately 1.7 times higher than that of graphite anodes. However, Si undergoes severe volume changes ... ...

Abstract	All-solid-state batteries comprising Si anodes are promising materials for energy storage in electronic vehicles because their energy density is approximately 1.7 times higher than that of graphite anodes. However, Si undergoes severe volume changes during cycling, resulting in the loss of electronic and ionic conduction pathways and rapid capacity fading. To address this challenge, we developed composite anodes with a nanoporous Si fiber network structure in sulfide-based solid electrolytes (SEs) and conductive additives. Nanoporous Si fibers were fabricated by electrospinning, followed by magnesiothermic reduction. The total pore volume of the fibers allowed pore shrinkage to compensate for the volumetric expansion of Li
Language	English
Publishing date	2023-10-10
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-023-44070-1
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Article: [112th Scientific Meeting of the Japanese Society of Internal Medicine: Presidential Lecture: Panel discussion: The Prevention of Disease Using the Food Function].

Maeda-Yamamoto, Mari

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine

2018 Volume 104, Issue 9, Page(s) 1819–1824

MeSH term(s)	Crops, Agricultural ; Diet ; Food Handling ; Humans ; Primary Prevention/methods
Language	Japanese
Publishing date	2018-09-12
Publishing country	Japan
Document type	Journal Article
ZDB-ID	952816-7
ISSN	1883-2083 ; 0021-5384
ISSN (online)	1883-2083
ISSN	0021-5384
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Article: Mortality After Hip and Spine Fractures in Patients With End-Stage Kidney Disease: A Systematic Review and Meta-Analysis.

Shimamura, Yoshinosuke / Kuniyoshi, Yasutaka / Ueta, Hiroshi / Miyauchi, Takamasa / Yamamoto, Mari / Tsujimoto, Yasushi

Cureus

2023 Volume 15, Issue 11, Page(s) e49636

Abstract: Fractures represent a major cause of disability in the elderly, and patients with fractures exhibit a higher mortality rate than those without. Fractures are also an important health problem among patients with end-stage kidney disease (ESKD) requiring ... ...

Abstract	Fractures represent a major cause of disability in the elderly, and patients with fractures exhibit a higher mortality rate than those without. Fractures are also an important health problem among patients with end-stage kidney disease (ESKD) requiring hemodialysis, peritoneal dialysis, or kidney transplantation. To the best of our knowledge, no study in the literature has yet quantitatively summarized the mortality rates, and a summary of evidence on post-hip and spine fracture mortality in patients with ESKD is lacking. The purpose of this study is to quantitatively evaluate the mortality rate, one-year mortality rate, and five-year mortality rate after hip and spine fractures in patients with ESKD receiving kidney replacement therapy. The MEDLINE, Cochrane Central Register of Controlled Trials (CENTRAL), Embase, and ClinicalTrials.gov databases were comprehensively searched for reports on mortality rate and time-period mortality in patients with ESKD after hip or spine fractures up to June 2022. Prospective and retrospective cohort studies, as well as case series involving four or more patients, were included. Pooled mortality rate, one-year rate, and five-year mortality rate with 95% confidence intervals (CIs) were examined using a random-effects model. The risk of bias was assessed using the Joanna Briggs Institute (JBI) Prevalence Critical Appraisal Tool. Additionally, heterogeneity between studies was evaluated. A total of 26 studies were included in this meta-analysis. The one-year and five-year mortality rates after hip and spine fractures were 215.35-774.0 per 1,000 person-year and 148-194.1 per 1,000 person-year, respectively. After hip fractures, the one-year mortality rate was 27% (95% CI: 18-38%, I
Language	English
Publishing date	2023-11-29
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2747273-5
ISSN	2168-8184
ISSN	2168-8184
DOI	10.7759/cureus.49636
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Article ; Online: Absolute lymphocyte count and neutrophil-to-lymphocyte ratio as predictors of CDK 4/6 inhibitor efficacy in advanced breast cancer.

Nakamoto, Shogo / Shien, Tadahiko / Iwamoto, Takayuki / Kubo, Shinichiro / Yamamoto, Mari / Yamashita, Tetsumasa / Kuwahara, Chihiro / Ikeda, Masahiko

Scientific reports

2024 Volume 14, Issue 1, Page(s) 9869

Abstract: Cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i) are the standard agents for treating patients with estrogen receptor-positive and human epidermal growth factor receptor 2-negative advanced breast cancer (ER + HER2 - ABC). However, markers predicting ...

Abstract	Cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i) are the standard agents for treating patients with estrogen receptor-positive and human epidermal growth factor receptor 2-negative advanced breast cancer (ER + HER2 - ABC). However, markers predicting the outcomes of CDK4/6i treatment have yet to be identified. This study was a single-center retrospective cohort study. We retrospectively evaluated 101 patients with ER + HER2 - ABC receiving CDK4/6i in combination with endocrine therapy at Fukuyama City Hospital between November 2017 and July 2021. We investigated the clinical outcomes and the safety of CDK4/6i treatment, and the absolute lymphocyte count (ALC) and neutrophil-to-lymphocyte ratio (NLR) as predictive markers for CDK4/6i. We defined the cut-off values as 1000/μL for ALC and 3 for NLR, and divided into "low" and "high" groups, respectively. We evaluated 43 and 58 patients who received abemaciclib and palbociclib, respectively. Patients with high ALC and low NLR had significantly longer overall survival than those with low ALC and high NLR (high vs. low; ALC: HR 0.29; 95% CI 0.12-0.70; NLR: HR 2.94; 95% CI 1.21-7.13). There was no significant difference in efficacy between abemaciclib and palbociclib and both had good safety profiles. We demonstrated that ALC and NLR might predict the outcomes of CDK4/6i treatment in patients with ER + HER2 - ABC.
MeSH term(s)	Humans ; Female ; Breast Neoplasms/drug therapy ; Breast Neoplasms/pathology ; Breast Neoplasms/mortality ; Breast Neoplasms/blood ; Cyclin-Dependent Kinase 4/antagonists & inhibitors ; Neutrophils ; Cyclin-Dependent Kinase 6/antagonists & inhibitors ; Middle Aged ; Lymphocytes/metabolism ; Lymphocyte Count ; Retrospective Studies ; Protein Kinase Inhibitors/therapeutic use ; Aged ; Adult ; Pyridines/therapeutic use ; Piperazines/therapeutic use ; Aminopyridines/therapeutic use ; Benzimidazoles/therapeutic use ; Aged, 80 and over ; Receptor, ErbB-2/metabolism ; Receptor, ErbB-2/antagonists & inhibitors ; Treatment Outcome
Chemical Substances	Cyclin-Dependent Kinase 4 (EC 2.7.11.22) ; Cyclin-Dependent Kinase 6 (EC 2.7.11.22) ; Protein Kinase Inhibitors ; palbociclib (G9ZF61LE7G) ; abemaciclib (60UAB198HK) ; Pyridines ; Piperazines ; CDK6 protein, human (EC 2.7.11.22) ; Aminopyridines ; CDK4 protein, human (EC 2.7.11.22) ; Benzimidazoles ; Receptor, ErbB-2 (EC 2.7.10.1)
Language	English
Publishing date	2024-04-30
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-60101-x
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Article ; Online: Impact of anti-squamous cell carcinoma antigen antibodies on serum squamous cell carcinoma antigen levels measured by chemiluminescent immunoassay and chemiluminescent enzyme immunoassay.

Oyabu, Chinami / Sato, Itsuko / Yamamoto, Mari / Imanishi, Takamitsu / Sendo, Sho / Yano, Yoshihiko

Laboratory medicine

2023 Volume 55, Issue 3, Page(s) 341–346

Abstract: Objective: The serum squamous cell carcinoma antigen (SCCA) level is a well-known tumor marker for squamous cell carcinoma. In this study, we examined the impact of immunoglobulin (Ig)-bound macromolecular SCCA on serum SCCA levels measured by 2 ... ...

Abstract	Objective: The serum squamous cell carcinoma antigen (SCCA) level is a well-known tumor marker for squamous cell carcinoma. In this study, we examined the impact of immunoglobulin (Ig)-bound macromolecular SCCA on serum SCCA levels measured by 2 different methods. Methods: Seventy-five serum samples with an SCCA level >5.0 ng/mL as determined by a chemiluminescent immunoassay (CLIA) were also analyzed using a chemiluminescent enzyme immunoassay (CLEIA). The levels of IgG- and IgA-type anti-SCCA antibodies, which form immunoglobulins and macromolecules, respectively, were determined using an enzyme-linked immunosorbent assay. An absorption test was performed to confirm the presence of anti-SCCA antibodies. Results: The correlation coefficient between the values measured by CLEIA and CLIA was 0.768. The ratio of SCCA levels measured by CLEIA to those measured by CLIA in 14 samples with IgG-type anti-SCCA antibodies was significantly lower than that in samples without these antibodies (P < .031). Absorption tests showed that SCCA levels measured by CLIA might be falsely high in samples with IgG-type anti-SCCA antibodies, probably due to reactions with SCCA1. Conclusion: The level of SCCA as measured by CLIA and CLEIA methods correlate well, but the presence of SCCA antibodies can affect the results of the CLIA method.
MeSH term(s)	Humans ; Antigens, Neoplasm/blood ; Antigens, Neoplasm/immunology ; Serpins/blood ; Luminescent Measurements/methods ; Carcinoma, Squamous Cell/blood ; Carcinoma, Squamous Cell/diagnosis ; Biomarkers, Tumor/blood ; Female ; Male ; Middle Aged ; Aged ; Immunoassay/methods ; Immunoassay/standards ; Immunoenzyme Techniques/methods ; Immunoenzyme Techniques/standards ; Enzyme-Linked Immunosorbent Assay/methods ; Enzyme-Linked Immunosorbent Assay/standards
Chemical Substances	squamous cell carcinoma-related antigen ; Antigens, Neoplasm ; Serpins ; Biomarkers, Tumor
Language	English
Publishing date	2023-09-14
Publishing country	England
Document type	Journal Article
ZDB-ID	391758-7
ISSN	1943-7730 ; 0007-5027
ISSN (online)	1943-7730
ISSN	0007-5027
DOI	10.1093/labmed/lmad088
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Article ; Online: Insomnia in primary care: Considerations for screening, assessment, and management.

Yamamoto, Mari / Lim, Christopher T / Huang, Heather / Spottswood, Margaret / Huang, Hsiang

The journal of medicine access

2023 Volume 7, Page(s) 27550834231156727

Abstract: Insomnia, including insomnia disorder, is a common but often overlooked complaint in primary care settings. It is a risk factor for various medical and psychiatric diagnoses and is associated with substantial health care costs. While cognitive behavioral ...

Abstract	Insomnia, including insomnia disorder, is a common but often overlooked complaint in primary care settings. It is a risk factor for various medical and psychiatric diagnoses and is associated with substantial health care costs. While cognitive behavioral therapy for insomnia (CBT-I) is the first-line treatment for insomnia disorder, access to CBT-I is limited. This article provides a pragmatic approach to screening, assessment, and treatment of insomnia in the primary care setting, promoting a population health approach. The authors review the role of CBT-I, treatment of comorbid conditions, and pharmacologic recommendations in working with primary care patients with insomnia. In addition, the authors highlight the potential utility of technology in improving access to insomnia care.
Language	English
Publishing date	2023-03-15
Publishing country	United States
Document type	Journal Article ; Review
ISSN	2755-0834
ISSN (online)	2755-0834
DOI	10.1177/27550834231156727
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