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  1. Article ; Online: Physiological functions of poorly absorbed polyphenols via the glucagon-like peptide-1.

    Yamashita, Yoko

    Bioscience, biotechnology, and biochemistry

    2024  Volume 88, Issue 5, Page(s) 493–498

    Abstract: Polyphenols are compounds of plant origin with several documented bioactivities related to health promotion. Some polyphenols are hard to be absorbed into the body due to their structural characteristics. This review focuses on the health beneficial ... ...

    Abstract Polyphenols are compounds of plant origin with several documented bioactivities related to health promotion. Some polyphenols are hard to be absorbed into the body due to their structural characteristics. This review focuses on the health beneficial effects of polyphenols mediated by intestinal hormones, particularly related to the systemic functions through the secretion of glucagon-like peptide-1 (GLP-1), an enteric hormone that stimulates postprandial insulin secretion. GLP-1 is secreted from L cells in the distal small intestine. Therefore, some poorly absorbed polyphenols are known to have the ability to act on the intestines and promote GLP-1 secretion. It has been reported that it not only reduces hyperglycemia but also prevents obesity by reduction of overeating and improves blood vessel function. This review discusses examples of health effects of polyphenols mediated by GLP-1 secretion.
    MeSH term(s) Glucagon-Like Peptide 1/metabolism ; Polyphenols/metabolism ; Polyphenols/pharmacology ; Humans ; Animals ; Intestinal Absorption/drug effects ; Obesity/metabolism ; Obesity/drug therapy ; Insulin/metabolism
    Chemical Substances Glucagon-Like Peptide 1 (89750-14-1) ; Polyphenols ; Insulin
    Language English
    Publishing date 2024-02-19
    Publishing country England
    Document type Review ; Journal Article
    ZDB-ID 1106450-x
    ISSN 1347-6947 ; 0916-8451
    ISSN (online) 1347-6947
    ISSN 0916-8451
    DOI 10.1093/bbb/zbae021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: The 3-Minute Burpee Test: A Minimalistic Alternative to the Conventional Estimated Oxygen Uptake Test.

    Yamashita, Yohei

    Cureus

    2023  Volume 15, Issue 3, Page(s) e35841

    Abstract: Background Maximal oxygen uptake and muscle strength are fundamental components of physical fitness. Improving these capacities is highly beneficial to health. The validity of maximal oxygen uptake and muscle strength has been widely emphasized in ... ...

    Abstract Background Maximal oxygen uptake and muscle strength are fundamental components of physical fitness. Improving these capacities is highly beneficial to health. The validity of maximal oxygen uptake and muscle strength has been widely emphasized in clinical, sports, and research-related settings. However, many of the previous tests required special equipment and space. Aim This study examined the effectiveness of field tests that do not require special equipment or space. Materials and methods The relationship between the 3-minute burpee test (3MBT) and estimated maximal oxygen uptake (Yo-Yo intermittent recovery test (Yo-Yo IRT)) using whole-body muscle groups was examined. The subjects were young men (n=127) with a history of exercising at least once a week. Results A strong relationship between 3MBT and Yo-YoIRT was shown (p<0.001). Conclusions The 3MBT is a field test that can be performed anytime and anywhere there is space for plank and standing postures. Because it is very brief, efficient, and uses muscle groups throughout the body, it is effective and potentially quite useful as a new field test.
    Language English
    Publishing date 2023-03-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.35841
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Relationship Between the Japanese Physical Fitness Test and the 3-Minute Burpee Test.

    Yamashita, Yohei

    Cureus

    2023  Volume 15, Issue 12, Page(s) e50710

    Abstract: Background Japan has conducted a national physical fitness survey every year since 1964, when the first Tokyo Summer Olympics were held. The survey is a test that evaluates eight physical fitness components: speed, total body endurance, instantaneous ... ...

    Abstract Background Japan has conducted a national physical fitness survey every year since 1964, when the first Tokyo Summer Olympics were held. The survey is a test that evaluates eight physical fitness components: speed, total body endurance, instantaneous force, dexterity, muscle strength, muscular endurance, flexibility, and agility, but it requires specialized equipment and space, and it takes time to measure them all. Aims The purpose of this study was to examine the relationship between the 3-minute burpee test (3MBT), which has been reported to be associated with various physical fitness components, and a "new physical fitness test." Materials and methods The relationship between the "new physical fitness test" and the 3MBT was examined in 122 college students (male=70, female=52) with no health problems. Results The "new physical fitness test" and the 3MBT showed a moderate relationship between the 20-m shuttle run (r = 0.685, p < 0.05), side stepping (r = 0.566, p < 0.05), standing long jump (r = 0.545, p < 0.05), grip strength (r = 0.461, p < 0.05), sit and reach (r = 0.305, p < 0.05), and sit-ups (r = 0.572, p < 0.05), indicating a moderate relationship. Because this study used the Pearson product-rate correlation analysis, it is not possible to definitively assert a relationship with physical fitness factors. Conclusions However, the 3MBT is a very useful test because it requires whole-body strength, power, endurance, and aerobic capacity.
    Language English
    Publishing date 2023-12-18
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.50710
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Utility of Rivaroxaban for Real-World Patients With Venous Thromboembolism.

    Yamashita, Yugo

    Circulation journal : official journal of the Japanese Circulation Society

    2023  Volume 87, Issue 9, Page(s) 1185–1186

    MeSH term(s) Humans ; Rivaroxaban/adverse effects ; Venous Thromboembolism/drug therapy ; Anticoagulants ; Factor Xa Inhibitors/adverse effects
    Chemical Substances Rivaroxaban (9NDF7JZ4M3) ; Anticoagulants ; Factor Xa Inhibitors
    Language English
    Publishing date 2023-05-24
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 2068090-9
    ISSN 1347-4820 ; 1346-9843
    ISSN (online) 1347-4820
    ISSN 1346-9843
    DOI 10.1253/circj.CJ-23-0291
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Development of chiral potassium strong Brønsted base catalysts for enantioselective carbon-carbon bond-forming reactions.

    Yamashita, Yasuhiro

    Chemical communications (Cambridge, England)

    2022  Volume 58, Issue 8, Page(s) 1078–1088

    Abstract: Chiral alkaline metal Brønsted bases are traditional and reliable promoters in enantioselective catalysis. Here, new chiral potassium strong base catalysts were developed for enantioselective carbon-carbon bond-forming reactions of weakly acidic carbon ... ...

    Abstract Chiral alkaline metal Brønsted bases are traditional and reliable promoters in enantioselective catalysis. Here, new chiral potassium strong base catalysts were developed for enantioselective carbon-carbon bond-forming reactions of weakly acidic carbon pronucleophiles. Chiral potassium amide or alkyl potassium catalyzed enantioselective addition reactions to imines or α,β-unsaturated amides with good to high enantioselectivities. The good potential of chiral potassium Brønsted bases to act as proton transfer catalysts has been shown.
    Language English
    Publishing date 2022-01-25
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1472881-3
    ISSN 1364-548X ; 1359-7345 ; 0009-241X
    ISSN (online) 1364-548X
    ISSN 1359-7345 ; 0009-241X
    DOI 10.1039/d1cc06328f
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Editorial: COVID-19 and Venous Thromboembolism.

    Yamashita, Yugo

    Frontiers in cardiovascular medicine

    2021  Volume 8, Page(s) 818231

    Language English
    Publishing date 2021-12-20
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2781496-8
    ISSN 2297-055X
    ISSN 2297-055X
    DOI 10.3389/fcvm.2021.818231
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Effect of High-Intensity With Short-Duration Re-Warm-Up on Subsequent Performance in a Cold Environment.

    Yamashita, Yuto / Umemura, Yoshihisa

    Journal of strength and conditioning research

    2024  

    Abstract: Abstract: Yamashita, Y and Umemura, Y. Effect of high-intensity with short-duration re-warm up on subsequent performance in a cold environment. J Strength Cond Res XX(X): 000-000, 2024-The aim of this study was to investigate the effect of high- ... ...

    Abstract Abstract: Yamashita, Y and Umemura, Y. Effect of high-intensity with short-duration re-warm up on subsequent performance in a cold environment. J Strength Cond Res XX(X): 000-000, 2024-The aim of this study was to investigate the effect of high-intensity, short-duration re-warm-up (RW) during half time (HT) on subsequent performance in a cold environment. Eleven male subjects (age, 21 ± 2 years; height, 172.4 ± 4.5 cm; body mass, 65.6 ± 7.1 kg; V̇o2max, 47.5 ± 4.8 ml·kg-1·min-1) performed 2 experimental trials comprising 40 minutes of intermittent cycling exercise, which consisted of 15-second rest, 25-second unloading cycling, 10-second high-intensity cycling, and 70-second moderate-intensity cycling as the first half. In the second half, a cycling intermittent-sprint protocol (CISP) was performed, separated by a 15-minute HT period in cold conditions (5 °C, 50% relative humidity). Two experimental trials were included in a random order: (a) approximately 1 minute of high-intensity, short-duration RW (3 sets of 3-second maximal pedaling [body weight × 0.075 kp]) trial high-intensity intermittent cycling trials (HII); (b) 15 minutes of seated rest trial (CON). Cycling intermittent-sprint protocol consisted of 10 sets of a 2-minute exercise protocol, and each set consisted of 10-second rest, 5-second maximal pedaling (body weight × 0.075 kp), and 105-second active recovery at 50% maximum oxygen uptake (V̇o2max). Peak power output of 5-second maximal pedaling during CISP was higher in HII trials than in CON trials (HII: 807 ± 81 W, CON: 791 ± 78 W, p < 0.05). There was no significant difference in rectal temperature between trial types (p > 0.05). These results suggest that high-intensity, short-duration RW may be a useful HT strategy for improving subsequent performance in cold environments.
    Language English
    Publishing date 2024-04-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1156349-7
    ISSN 1533-4287 ; 1064-8011
    ISSN (online) 1533-4287
    ISSN 1064-8011
    DOI 10.1519/JSC.0000000000004754
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Role of contrast-enhanced harmonic endoscopic ultrasonography (EUS) and EUS elastography in pancreatic lesions.

    Yamashita, Yasunobu / Kitano, Masayuki

    Clinical endoscopy

    2024  Volume 57, Issue 2, Page(s) 164–174

    Abstract: Pancreatic cancers have a poor prognosis, and their incident rates have risen. Endoscopic ultrasonography (EUS) is an efficient and reliable diagnostic modality for pancreatic lesions, providing high spatial resolution. However, while EUS helps to detect ...

    Abstract Pancreatic cancers have a poor prognosis, and their incident rates have risen. Endoscopic ultrasonography (EUS) is an efficient and reliable diagnostic modality for pancreatic lesions, providing high spatial resolution. However, while EUS helps to detect minor pancreatic lesions, nearly all solid pancreatic lesions are hypoechoic, which creates difficulty in making differential diagnoses of pancreatic lesions. When diagnosing pancreatic lesions, the performance of image-enhanced EUS techniques is essential, such as EUS elastography or contrast-enhanced harmonic EUS (CH-EUS). CH-EUS diagnosis is based on assessing the vascularity of lesions, whereas tissue elasticity is measured via EUS elastography. Elastography is either strain or shear-wave, depending on the different mechanical properties being evaluated. The usefulness of enhanced EUS techniques is demonstrated in this review for the differential diagnosis of pancreatic lesions, including solid and cystic lesions, and pancreatic cancer staging.
    Language English
    Publishing date 2024-01-17
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 2643507-X
    ISSN 2234-2443 ; 2234-2400
    ISSN (online) 2234-2443
    ISSN 2234-2400
    DOI 10.5946/ce.2023.074
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Efficient Radical-Mediated Intermolecular α-Alkylation Reactions of Carbonyl Compounds with Nonactivated Alkenes.

    Yamashita, Yasuhiro / Kobayashi, Shū

    Chemistry, an Asian journal

    2024  , Page(s) e202400319

    Abstract: Alkylation reactions are fundamental carbon-carbon bond-forming reactions in synthetic organic chemistry. Among them, intermolecular α-alkylation reactions of carbonyl compounds with alkenes are important because they are more atom-economical than the ... ...

    Abstract Alkylation reactions are fundamental carbon-carbon bond-forming reactions in synthetic organic chemistry. Among them, intermolecular α-alkylation reactions of carbonyl compounds with alkenes are important because they are more atom-economical than the equivalent processes using alkyl halides. However, intermolecular reactions with nonactivated alkenes such as 1-hexene, which can allow the use of a wide range of valuable substrates, have been considered to be very challenging for a long time. In this review, radical-mediated intermolecular α-alkylation reactions of carbonyl compounds with nonactivated alkenes are discussed. The examples are grouped into three types of reactions: peroxide-mediated reactions, metal-oxidant-mediated reactions, and photoactivated reactions. Photoredox-catalyzed alkylation reactions under visible-light irradiation are discussed as a particularly promising recent hot topic. This review provides brief history and new prospects on the α-alkylation process with nonactivated alkenes using α-carbonyl radical species.
    Language English
    Publishing date 2024-04-26
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2233006-9
    ISSN 1861-471X ; 1861-4728
    ISSN (online) 1861-471X
    ISSN 1861-4728
    DOI 10.1002/asia.202400319
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Deep vein thrombosis of upper extremities in the era of direct Oral anticoagulants.

    Yamashita, Yugo

    International journal of cardiology

    2021  Volume 339, Page(s) 164–165

    MeSH term(s) Administration, Oral ; Anticoagulants/adverse effects ; Humans ; Upper Extremity ; Venous Thrombosis/diagnostic imaging ; Venous Thrombosis/drug therapy
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2021-07-21
    Publishing country Netherlands
    Document type Editorial ; Comment
    ZDB-ID 779519-1
    ISSN 1874-1754 ; 0167-5273
    ISSN (online) 1874-1754
    ISSN 0167-5273
    DOI 10.1016/j.ijcard.2021.07.039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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