Article ; Online: Non-surgical ablation for breast cancer: an emerging therapeutic option.
2024 Volume 25, Issue 3, Page(s) e114–e125
Abstract: Non-surgical ablation is emerging as an alternative local therapy option for patients with early-stage breast cancer and encompasses two main types of percutaneous therapeutic procedures: radiofrequency ablation and cryoablation. Both techniques involve ... ...
Abstract | Non-surgical ablation is emerging as an alternative local therapy option for patients with early-stage breast cancer and encompasses two main types of percutaneous therapeutic procedures: radiofrequency ablation and cryoablation. Both techniques involve obliteration of a spherical lesion and feasibility studies have shown that complete tumour ablation is achievable with good or excellent cosmetic results. Although few clinical studies have directly compared non-surgical ablation with conventional surgical resection, observational studies indicate that clinical outcomes are favourable with acceptable rates of local control and no detriment to long-term survival. There remain outstanding issues with these percutaneous ablative techniques that require resolution before they could be incorporated into routine clinical practice. Hence, a consensus meeting was convened to discuss the challenges of non-surgical ablation and clarify indications for its use alongside clinical management pathways. In this Policy Review we will address some of the broader biological aspects of non-surgical ablation, including immune-modulatory effects and potential novel applications for the future. |
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MeSH term(s) | Female ; Humans ; Breast Neoplasms/surgery ; Catheter Ablation ; Consensus ; Critical Pathways |
Language | English |
Publishing date | 2024-02-02 |
Publishing country | England |
Document type | Journal Article ; Review |
ZDB-ID | 2049730-1 |
ISSN | 1474-5488 ; 1470-2045 |
ISSN (online) | 1474-5488 |
ISSN | 1470-2045 |
DOI | 10.1016/S1470-2045(23)00615-0 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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