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Article ; Online: Deformation characteristics of overlying strata in room and pillar mined-out areas under coal pillar instability

Yaming Liu / Tianfeng Gu / Yanchao Wang / Wei Xiong / Xuanyu Yang

Scientific Reports, Vol 14, Iss 1, Pp 1-

2024 Volume 12

Abstract: Abstract Under the condition of small roof deformation before the occurrence of fractures and collapse in room and pillar mined-out areas caused by coal pillar instability, the surface deformation may be large, which threatens the safety of ground ... ...

Abstract	Abstract Under the condition of small roof deformation before the occurrence of fractures and collapse in room and pillar mined-out areas caused by coal pillar instability, the surface deformation may be large, which threatens the safety of ground structures. Interferometric synthetic aperture radar, geophysical exploration, geotechnical exploration and physical simulation tests were conducted to analyse the deformation and development mechanism of the overlying strata in the mined-out area in this case. The results show that in terms of surface deformation, the surface deformation caused by coal pillar instability in the room and pillar mined-out area exhibits the slow deformation stage, uniform deformation stage and accelerated deformation stage. In terms of deformation of overlying strata, after the completion of room and pillar mining, a strip-shaped deformation area and trapezoidal deformation area are developed in the overlying rock. With the occurrence of coal pillar instability, a trapezoidal deformation area and inverted funnel-shaped deformation area are developed in the overlying rock. The deformation characteristics of unconsolidated formations transition from trapezoidal deformation after room and pillar mining to funnel-shaped deformation due to coal pillar instability. Moreover, the maximum surface deformation point is located at the centre of the funnel. In terms of spatial morphology of mined-out area deformation, the maximum surface deformation point corresponds to the position of the initial coal pillar instability and the crack in the mined-out area roof along the vertical direction. The mined-out area treatment method can be optimized based on the deformation characteristics of the overlying strata in the room and pillar mined-out area under the condition of coal pillar instability.
Keywords	Medicine ; R ; Science ; Q
Subject code	550
Language	English
Publishing date	2024-01-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Simulation Study on Nanofluid Heat Transfer in Immersion Liquid-Cooled Server

Shuai Wen / Gang Chen / Qiao Wu / Yaming Liu

Applied Sciences, Vol 13, Iss 7575, p

2023 Volume 7575

Abstract: In order to study the application of nanofluids for enhancing heat transfer in the field of liquid-cooled data centers, a mathematical and physical model of liquid-cooled servers was established in this paper. FC–40 was used as the server cooling liquid ... ...

Abstract	In order to study the application of nanofluids for enhancing heat transfer in the field of liquid-cooled data centers, a mathematical and physical model of liquid-cooled servers was established in this paper. FC–40 was used as the server cooling liquid base, and simulation studies were conducted on the flow and heat transfer of five types of nanofluid: Cu–FC40, CuO–FC40, Al–FC40, Al 2 O 3 –FC40, and TiO 2 –FC40. The results showed that using Al–FC40 nanofluids as the cooling medium had the best heat transfer effect. Under the same operating conditions, the average Nusselt number Nu and friction resistance coefficient f of five types of nanofluid were analyzed, and the heat transfer state of Al–FC40 nanofluid had the smallest f . Further analysis was conducted on the influence of ‘nanoparticle volume fraction’ α and ‘server inlet flow rate’ u on fluid flow and heat transfer. Our research found that an increase in α and the acceleration of u can effectively reduce the surface temperature of server components. As u increases, Nu gradually increases and f generally decreases, but the amplitude of the increase and decrease becomes smoother.
Keywords	immersion liquid cooling ; nanoparticles ; enhanced heat exchange ; numerical simulation ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	621
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: ST-MAE

Rongyun Zhang / Yufeng Du / Peicheng Shi / Lifeng Zhao / Yaming Liu / Haoran Li

Complex & Intelligent Systems, Vol 9, Iss 5, Pp 4837-

robust lane detection in continuous multi-frame driving scenes based on a deep hybrid network

2022 Volume 4855

Abstract: Abstract Lane detection is one of the key techniques to realize advanced driving assistance and automatic driving. However, lane detection networks based on deep learning have significant shortcomings. The detection results are often unsatisfactory when ... ...

Abstract	Abstract Lane detection is one of the key techniques to realize advanced driving assistance and automatic driving. However, lane detection networks based on deep learning have significant shortcomings. The detection results are often unsatisfactory when there are shadows, degraded lane markings, and vehicle occlusion lanes. Therefore, a continuous multi-frame image sequence lane detection network is proposed. Specifically, the continuous six-frame image sequence is input into the network, in which the scene information of each frame image is extracted by an encoder composed of Swin Transformer blocks and input into the PredRNN. Continuous multi-frame of the driving scene is modeled as time-series by ST-LSTM blocks, and then, the shape changes and motion trajectory in the spatiotemporal sequence are effectively modeled. Finally, through the decoder composed of Swin Transformer blocks, the features are obtained and reconstructed to complete the detection task. Extensive experiments on two large-scale datasets demonstrate that the proposed method outperforms the competing methods in lane detection, especially in handling difficult situations. Experiments are carried out based on the TuSimple dataset. The results show: for easy scenes, the validation accuracy is 97.46%, the test accuracy is 97.37%, and the precision is 0.865. For complex scenes, the validation accuracy is 97.38%, the test accuracy is 97.29%, and the precision is 0.859. The running time is 4.4 ms. Experiments are carried out based on the CULane dataset. The results show that, for easy scenes, the validation accuracy is 97.03%, the test accuracy is 96.84%, and the precision is 0.837. For complex scenes, the validation accuracy is 96.18%, the test accuracy is 95.92%, and the precision is 0.829. The running time is 6.5 ms.
Keywords	Lane detection ; Deep learning ; Swin transformer ; Continuous multi-frame ; Electronic computers. Computer science ; QA75.5-76.95 ; Information technology ; T58.5-58.64
Subject code	006
Language	English
Publishing date	2022-11-01T00:00:00Z
Publisher	Springer
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The effect of particle size on the dynamics of self-electrophoretic Janus micromotors, sputtering distribution, and rectifying voltage

Shuaishuai Meng / Yueyue Zhang / Yaming Liu / Zhenchao Zhang / Kunpeng Ma / Xiaowen Chen / Qiang Gao / Xing Ma / Wei Wang / Huanhuan Feng

JCIS Open, Vol 5, Iss , Pp 100046- (2022)

2022

Abstract: Micromotors have gained increasing attention in last two decades, due to their controllable self-propulsion maneuverability at micro scales. However, the effect of particle size on micromotors is still vague and interwoven due to the micromotors’ size, ... ...

Abstract	Micromotors have gained increasing attention in last two decades, due to their controllable self-propulsion maneuverability at micro scales. However, the effect of particle size on micromotors is still vague and interwoven due to the micromotors’ size, polydisperse distribution, and structural variations. Microfluidic technology is used to clarify the phenomenon, due to its precise micro scale fabrication. Herein, we fabricated a H2O2-driven self-electrophoretic Janus micromotor and systematically explored the effects of particle size on their dynamics, the sputtering distribution, and the rectifying voltages. Their speeds were found to be inversely proportional to their sizes. When the particle size was fixed, their speeds increased as coating thickness increased until its hemisphere was fully coated, and this critical coating thickness was also proportional to the sizes of the micromotors. As further investigation goes on, we noticed that electrical voltage to rectify micromotor was proportional to its size too. To summarize, our results showed that larger micromotors moved more slowly, required a thicker metal coating to reach full speeds, and needed higher voltages to be rectified. Through all of these investigations, we believed that microfluidic technology is a valuable tool, which can systematically probe micromotors dynamics and clarify our understanding of micromotors behaviors.
Keywords	Particle size ; Self-electrophoretic Janus micromotor ; Sputtering distribution ; Rectifying voltage ; Dynamics research ; Physical and theoretical chemistry ; QD450-801 ; Chemical technology ; TP1-1185
Subject code	620
Language	English
Publishing date	2022-04-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Apolipoprotein H induces sex-specific steatohepatitis and gut dysbiosis during chronic hepatitis B infection

Yaming Liu / Yangtao Wu / Xiaoming Jiang / Bo Chen / Jing Lu / Zexin Cai / Baorong Fu / Wei Zheng / Ruihong Wu / Gang Chen / Shulan Tian / Jianlin Ren

iScience, Vol 26, Iss 3, Pp 106100- (2023)

2023

Abstract: Summary: Apolipoprotein H (APOH) is involved in lipid metabolism and functions as an acute-phase protein during hepatitis B virus (HBV) infection. Herein, we explored whether APOH acts on the development of fatty liver upon chronic HBV infection. Serum ... ...

Abstract	Summary: Apolipoprotein H (APOH) is involved in lipid metabolism and functions as an acute-phase protein during hepatitis B virus (HBV) infection. Herein, we explored whether APOH acts on the development of fatty liver upon chronic HBV infection. Serum APOH level was significantly lower in cirrhosis patients than in healthy controls or patients with chronic infection. It showed sex bias, with elevated levels in female patients with chronic infection. Also, serum APOH levels were negatively correlated with HBV surface antigen (HBsAg) but positively correlated with albumin and triglyceride levels. In In vitro HBV infection model, HBV upregulated APOH expression in a non-temporal manner, and HBsAg levels were elevated by silencing APOH. RNA sequencing (RNA-seq) demonstrated bidirectional expression of APOH, which impacted the immunoregulation upon infection or the metabolic regulation in HepG2.2.15 cells. Then, ApoH−/− mice with persistent HBV replication displayed steatohepatitis and gut microbiota dysbiosis with synergistic sex differences. Our study deciphers the roles of APOH in chronic liver diseases.
Keywords	Virology ; Human metabolism ; Microbiome ; Science ; Q
Subject code	570
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Comparison of intra-articular versus intravenous application of tranexamic acid in total knee arthroplasty

Yaming Liu / Fantao Meng / Gang Yang / Lingde Kong / Yong Shen

Archives of Medical Science, Vol 13, Iss 3, Pp 533-

a meta-analysis of randomized controlled trials

2017 Volume 540

Abstract: Introduction: There is much controversy about the optimal application of tranexamic acid (TXA) in total knee arthroplasty (TKA). The purpose of this meta-analysis was to compare the efficacy of the intra-articular and intravenous regimens of TXA in TKA. ... ...

Abstract	Introduction: There is much controversy about the optimal application of tranexamic acid (TXA) in total knee arthroplasty (TKA). The purpose of this meta-analysis was to compare the efficacy of the intra-articular and intravenous regimens of TXA in TKA. Material and methods : A literature search of the PubMed, Embase and Cochrane Library databases was performed. Randomized controlled trials comparing the result of intra-articular and intravenous application of TXA during TKA were included. The focus was on the outcomes of blood loss, transfusion requirement and thromboembolic complications. Results: Six studies were eligible for data extraction and meta-analysis. We found no statistically significant difference between intra-articular and intravenous administration of tranexamic acid in terms of total blood loss (WMD, 6.01; 95% CI: –96.78 to 108.79; p = 0.91), drain output (WMD = –20.26; 95% CI: –51.34 to 10.82; p = 0.20), hemoglobin drop (WMD = 0.33; 95% CI: –0.31 to 0.98; p = 0.31), or the incidences of transfusion (RR = 0.98; 95% CI: 0.56–1.70; p = 0.93) as well as deep vein thrombosis (RR = 0.49; 95% CI: 0.09–2.73; p = 0.42). Conclusions : In comparison with intravenous application of TXA, intra-articular application had a comparable effect on reducing blood loss and the transfusion rate without increasing the complication rate.
Keywords	tranexamic acid ; intra-articular ; intravenous ; total knee arthroplasty ; meta-analysis ; Medicine ; R
Language	English
Publishing date	2017-04-01T00:00:00Z
Publisher	Termedia Publishing House
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Shikonin induces programmed death of fibroblast synovial cells in rheumatoid arthritis by inhibiting energy pathways

Jiahui Li / Jinglong Pang / Zhe Liu / XianMing Ge / Yanan Zhen / Chen Chen Jiang / Yaming Liu / Qiang Huo / Yiming Sun / Hao Liu

Scientific Reports, Vol 11, Iss 1, Pp 1-

2021 Volume 13

Abstract: Abstract Shikonin is the main component of the traditional Chinese medicine comfrey, which can inhibit the activity of PKM2 by regulating glycolysis and ATP production. Rheumatoid arthritis synovial cells (RA-FLSs) have been reported to increase ... ...

Abstract	Abstract Shikonin is the main component of the traditional Chinese medicine comfrey, which can inhibit the activity of PKM2 by regulating glycolysis and ATP production. Rheumatoid arthritis synovial cells (RA-FLSs) have been reported to increase glycolytic activity and have other similar hallmarks of metabolic activity. In this study, we investigated the effects of shikonin on glycolysis, mitochondrial function, and cell death in RA-FLSs. The results showed that shikonin induced apoptosis and autophagy in RA-FLSs by activating the production of reactive oxygen species (ROS) and inhibiting intracellular ATP levels, glycolysis-related proteins, and the PI3K-AKT-mTOR signaling pathway. Shikonin can significantly reduce the expression of apoptosis-related proteins, paw swelling in rat arthritic tissues, and the levels of inflammatory factors in peripheral blood, such as TNF-α, IL-6, IL-8, IL-10, IL-17A, and IL-1β while showing less toxicity to the liver and kidney.
Keywords	Medicine ; R ; Science ; Q
Subject code	610
Language	English
Publishing date	2021-09-01T00:00:00Z
Publisher	Nature Portfolio
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: PdCₓ nanocrystals with tunable compositions for alkyne semihydrogenation

Guo, Ruiyun / Qiang Chen / Xiang Li / Yaming Liu / Chaoqi Wang / Wei Bi / Caiyang Zhao / yanjun Guo / Mingshang Jin

Journal of materials chemistry A. 2019 Feb. 26, v. 7, no. 9

2019

Abstract: The palladium carbide (PdCₓ) material has shown great promise as an efficient catalyst for alkyne semihydrogenation. Difficulties in preparing stable PdCₓ catalysts have been recognized as the main obstacle. Here, we synthesized a highly stable and ... ...

Abstract	The palladium carbide (PdCₓ) material has shown great promise as an efficient catalyst for alkyne semihydrogenation. Difficulties in preparing stable PdCₓ catalysts have been recognized as the main obstacle. Here, we synthesized a highly stable and durable class of PdCₓ nanocrystals by treating pre-formed Pd nanocrystals with glucose under hydrothermal conditions. The C/Pd atomic ratios in the resultant PdCₓ nanocrystals can be varied from 0.04 to 0.18, simply by changing the reaction time. The catalytic results for semihydrogenation of 4-ethynyl-1,1′-biphenyl show that PdC₀.₁₈ nanocrystals exhibit an activity with a turnover frequency as high as 7896 h⁻¹, ∼7.6 and ∼38 times higher than that of commercial Pd/C and Lindlar catalysts, respectively, as well as a selectivity of >99%.
Keywords	alkynes ; catalysts ; glucose ; hydrogenation ; nanocrystals ; palladium
Language	English
Dates of publication	2019-0226
Size	p. 4714-4720.
Publishing place	The Royal Society of Chemistry
Document type	Article
ZDB-ID	2702232-8
ISSN	2050-7496 ; 2050-7488
ISSN (online)	2050-7496
ISSN	2050-7488
DOI	10.1039/c8ta12002a
Database	NAL-Catalogue (AGRICOLA)

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Article: Characterization of IgG glycosylation in rheumatoid arthritis patients by MALDI-TOF-MSn and capillary electrophoresis

Huang, Chuncui / Yaming Liu / Hongmei Wu / Dehui Sun / Yan Li

Analytical and bioanalytical chemistry. 2017 June, v. 409, no. 15

2017

Abstract: An analytical method based on the combination of multistage mass spectrometry (MSâ¿) and capillary electrophoresis (CE) was developed for the analysis of immunoglobulin G (IgG) glycosylation in rheumatoid arthritis (RA) patients. It has been recently ... ...

Abstract	An analytical method based on the combination of multistage mass spectrometry (MSâ¿) and capillary electrophoresis (CE) was developed for the analysis of immunoglobulin G (IgG) glycosylation in rheumatoid arthritis (RA) patients. It has been recently suggested that IgG glycosylation defect may be involved in RA immunopathogenesis. Complete characterization of glycans, including both qualitative and quantitative analysis, requires a combination of different techniques, and accurate, robust, sensitive, and high-throughput methodologies are important for analysis of clinical samples. In the present study, N-glycosylation of IgG in RA patients and in healthy people was characterized through identification of the released glycans using multistage matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF-MSâ¿), and quantitation by CE. Assignment of the IgG N-glycan structures was made through branching pattern analysis by MSâ¿ with high-throughput. Further accurate quantitation indicated that galactosylation and sialylation of IgG N-glycans in RA cases were significantly lower than in healthy subjects. The results indicate that CE coupled with MSâ¿ can identify abnormal glycosylation of IgG in RA patients compared with healthy people, and that the present work is useful for RA mechanism studies and RA diagnosis. Graphical Abstract Qualitative and quantitative analysis of IgG glycosylation in rheumatoid arthritis patients by MALDI-TOF-MSâ¿ and capillary electrophoresis
Keywords	capillary electrophoresis ; desorption ; glycosylation ; immunoglobulin G ; matrix-assisted laser desorption-ionization mass spectrometry ; patients ; people ; polysaccharides ; quantitative analysis ; rheumatoid arthritis
Language	English
Dates of publication	2017-06
Size	p. 3731-3739.
Publishing place	Springer Berlin Heidelberg
Document type	Article
ISSN	1618-2642
DOI	10.1007/s00216-017-0302-1
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Glycan analysis of colorectal cancer samples reveals stage-dependent changes in CEA glycosylation patterns

Qianqian Zhao / Tiancheng Zhan / Zaian Deng / Qianqian Li / Yaming Liu / Shaojie Yang / Dengbo Ji / Yan Li

Clinical Proteomics, Vol 15, Iss 1, Pp 1-

2018 Volume 11

Abstract: Abstract Background Carcinoembryonic antigen (CEA) is a glycoprotein associated with colorectal cancer (CRC). While the functions of its gene and protein have been fully characterized, its post-translational modifications in the context of CRC ... ...

Abstract	Abstract Background Carcinoembryonic antigen (CEA) is a glycoprotein associated with colorectal cancer (CRC). While the functions of its gene and protein have been fully characterized, its post-translational modifications in the context of CRC development remain undefined. Methods To show the correlation between the different stages of CRC development and changes in the glycosylation patterns of CEA, we analyzed CEA in tumor tissues (CEA-T) and paired tumor-adjacent normal tissues (CEA-A) from 53 colorectal cancer patients using a high-density lectin microarray containing 56 plant lectins. Results We detected higher expression levels of fucose, mannose and Thomsen–Friedenreich antigen, and lower expression levels of N-acetylgalactosamine, N-acetylglucosamine, galactose, branched and bisecting N-glycans on CEA in the tumor tissues relative to the tumor-adjacent normal tissues. Furthermore, a combinatorial assessment of 9 lectins is sufficient to distinguish CRC tumor tissues from tumor-adjacent normal tissues with 83% sensitivity and ~ 90% specificity. Moreover, the levels of N-acetylgalactosamine, mannose, galactose, N-acetylglucosamine on CEA showed a downward trend after first experiencing an increase at Stage II with the stages of CRC. Conclusions Our insights into the changing CEA glycosylation patterns and their role in the development of CRC highlight the importance of glycan variants on CEA for early clinical detection and staging of CRC.
Keywords	Colorectal cancer ; Carcinoembryonic antigen ; Glycosylation ; Lectin microarray ; Medicine ; R
Subject code	616
Language	English
Publishing date	2018-03-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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