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  1. Article ; Online: Attentional adversarial training for few-shot medical image segmentation without annotations.

    Awudong, Buhailiqiemu / Li, Qi / Liang, Zili / Tian, Lin / Yan, Jingwen

    PloS one

    2024  Volume 19, Issue 5, Page(s) e0298227

    Abstract: Medical image segmentation is a critical application that plays a significant role in clinical research. Despite the fact that many deep neural networks have achieved quite high accuracy in the field of medical image segmentation, there is still a ... ...

    Abstract Medical image segmentation is a critical application that plays a significant role in clinical research. Despite the fact that many deep neural networks have achieved quite high accuracy in the field of medical image segmentation, there is still a scarcity of annotated labels, making it difficult to train a robust and generalized model. Few-shot learning has the potential to predict new classes that are unseen in training with a few annotations. In this study, a novel few-shot semantic segmentation framework named prototype-based generative adversarial network (PG-Net) is proposed for medical image segmentation without annotations. The proposed PG-Net consists of two subnetworks: the prototype-based segmentation network (P-Net) and the guided evaluation network (G-Net). On one hand, the P-Net as a generator focuses on extracting multi-scale features and local spatial information in order to produce refined predictions with discriminative context between foreground and background. On the other hand, the G-Net as a discriminator, which employs an attention mechanism, further distills the relation knowledge between support and query, and contributes to P-Net producing segmentation masks of query with more similar distributions as support. Hence, the PG-Net can enhance segmentation quality by an adversarial training strategy. Compared to the state-of-the-art (SOTA) few-shot segmentation methods, comparative experiments demonstrate that the proposed PG-Net provides noticeably more robust and prominent generalization ability on different medical image modality datasets, including an abdominal Computed Tomography (CT) dataset and an abdominal Magnetic Resonance Imaging (MRI) dataset.
    MeSH term(s) Humans ; Neural Networks, Computer ; Image Processing, Computer-Assisted/methods ; Deep Learning ; Algorithms ; Magnetic Resonance Imaging/methods
    Language English
    Publishing date 2024-05-02
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0298227
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Mini approaches fasciotomy combined with vacuum sealing drainage for acute compartment syndrome caused by fractures in children.

    Hu, Jie / Yan, Jingwen / Su, Yuxi

    International orthopaedics

    2023  Volume 48, Issue 6, Page(s) 1481–1487

    Abstract: Purpose: Acute compartment syndrome (ACS) is an urgent, critical condition that requires immediate fasciotomy once diagnosed. Traditionally, fasciotomy of the forearms and lower leg involves one or two long approaches. Our previous study demonstrated ... ...

    Abstract Purpose: Acute compartment syndrome (ACS) is an urgent, critical condition that requires immediate fasciotomy once diagnosed. Traditionally, fasciotomy of the forearms and lower leg involves one or two long approaches. Our previous study demonstrated that mini approaches fasciotomy was an effective method to treat ACS. This study is aimed at further evaluating the limb functions and complications of mini approaches combined with vacuum sealing drainage (VSD) for treating ACS caused by fractures in the forearms and lower legs.
    Methods: This was a retrospective cross-sectional study, and after applying the inclusion and exclusion criteria, we reviewed 126 children who underwent mini treatment approaches for ACS from Jan 2008 to Jan 2022. The selected patients were divided into two groups: group A (ACS group; 58 patients aged 7.77±3.45 years) and group B (ACS combined with VSD; 68 patients aged 7.17±3.55 years). Patients' clinical data were collected. The patients were followed up, and muscle function in the forearms and lower legs was evaluated.
    Results: The overall incidence of lower legs and forearms ACS was 126/29642 (0.425%). The most common mechanisms of injury were fractures of the forearm (39/74, 52.7%), supracondylar humerus (31/74 41.9%), and elbow (4/74, 5.4%), while those for the lower legs were fractures of the proximal tibia (19/52, 36.5%), midshaft of tibia (25/52, 48.1%), and distal tibia (7/52, 13.5%). According to Flynn's assessment, no significant difference was observed between the two groups (p=0.151). However, the two groups showed significant differences in the hospitalization time (p=0.002) and incision infection rate (0.043).
    Conclusions: Mini approaches fasciotomy combined with VSD is an effective and safe method to treat ACS of the forearms and lower legs caused by fractures in children. This method involves a single-stage surgery and is associated with shorter hospitalization time and incision infection.
    MeSH term(s) Humans ; Child ; Fasciotomy/methods ; Compartment Syndromes/etiology ; Compartment Syndromes/surgery ; Retrospective Studies ; Male ; Female ; Cross-Sectional Studies ; Child, Preschool ; Fractures, Bone/surgery ; Fractures, Bone/complications ; Negative-Pressure Wound Therapy/methods ; Drainage/methods ; Treatment Outcome ; Adolescent ; Acute Disease
    Language English
    Publishing date 2023-09-21
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 80384-4
    ISSN 1432-5195 ; 0341-2695
    ISSN (online) 1432-5195
    ISSN 0341-2695
    DOI 10.1007/s00264-023-05984-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Assessing the impact of entrepreneurial education activity on entrepreneurial intention and behavior: role of behavioral entrepreneurial mindset

    Yan, Jingwen / Huang, Tian / Xiao, Yunxia

    Environ Sci Pollut Res. 2023 Feb., v. 30, no. 10 p.26292-26307

    2023  

    Abstract: This study explores the relationship between Entrepreneurship Education (EE) and Entrepreneurial Intentions (EI) using the Theory of Planned Behavior (TPB). From January through May of 2022, students from 10 Chinese institutions were surveyed using an ... ...

    Abstract This study explores the relationship between Entrepreneurship Education (EE) and Entrepreneurial Intentions (EI) using the Theory of Planned Behavior (TPB). From January through May of 2022, students from 10 Chinese institutions were surveyed using an online questionnaire. According to the research, students’ EI scores rose significantly after participating in EE. In addition, students in China had a more significant impact on EI regarding factors like perceived feasibility and desirability. This study extends the body of knowledge about the connection between prior exposure and early intervention (EI) by demonstrating the beneficial effects of PE on EI. In addition, the results suggest that girls have lower EI than males, which is good news for gender equality. Lastly, the behavioral entrepreneur attitude has a favorable correlation with EI. Policymakers and university administrators might use the findings to understand better how and when extracurricular activities (EE) improve students’ emotional intelligence (EI). A pioneering empirical study in a developing South-Asian setting shows the relevance of EE on EI among students at private universities. According to the study, EE generates EI, and entrepreneurial enthusiasm is crucial.
    Keywords education ; empirical research ; entrepreneurship ; gender ; questionnaires ; China
    Language English
    Dates of publication 2023-02
    Size p. 26292-26307.
    Publishing place Springer Berlin Heidelberg
    Document type Article ; Online
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-022-23878-w
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Research on the Impact of BMI on Enterprise Performance Based on the Antecedence of Risk Perception

    Yan Jingwen / Azmawani Abd Rahman / Tong Tong

    Sustainability, Vol 14, Iss 15844, p

    2022  Volume 15844

    Abstract: Despite research showing that business model innovation (BMI) can enhance performance and create competitive advantages for small- and medium-sized businesses, these firms often do not achieve the expected outcomes. A business model can undergo ... ...

    Abstract Despite research showing that business model innovation (BMI) can enhance performance and create competitive advantages for small- and medium-sized businesses, these firms often do not achieve the expected outcomes. A business model can undergo irreversible fundamental changes due to Business Model Innovation (BMI), resulting in high levels of risk, uncertainty, and ambiguity. An analysis of 350 Chinese small- and medium-sized enterprises (SMEs) was conducted to determine the impact of innovating a business model on firm performance. Based on BMI calculations, this study investigates whether organizational capabilities and growth strategies impact business performance. Even though BMI is not directly correlated with firm performance, growth in efficiency and novelty, organizational capacities, and revenue are all fully mediated by growth in those factors. Revenue growth, organizational capacity, and efficiency affect a firm’s performance. The model is proven to be valid by this study. In addition to providing guidelines on implementing BMI based on a company’s strategy, this study contributes to the existing literature on BMI efforts for small- and medium-sized businesses.
    Keywords innovative business models ; performance of companies ; strategy of companies ; organizational capabilities ; SMEs ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 650
    Language English
    Publishing date 2022-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article: Deciphering the tissue-specific functional effect of Alzheimer risk SNPs with deep genome annotation.

    Pugalenthi, Pradeep Varathan / He, Bing / Xie, Linhui / Nho, Kwangsik / Saykin, Andrew J / Yan, Jingwen

    Research square

    2024  

    Abstract: Alzheimer's disease (AD) is a highly heritable brain dementia, along with substantial failure of cognitive function. Large-scale genome-wide association studies (GWASs) have led to a significant set of SNPs associated with AD and related traits. GWAS ... ...

    Abstract Alzheimer's disease (AD) is a highly heritable brain dementia, along with substantial failure of cognitive function. Large-scale genome-wide association studies (GWASs) have led to a significant set of SNPs associated with AD and related traits. GWAS hits usually emerge as clusters where a lead SNP with the highest significance is surrounded by other less significant neighboring SNPs. Although functionality is not guaranteed even with the strongest associations in GWASs, lead SNPs have historically been the focus of the field, with the remaining associations inferred to be redundant. Recent deep genome annotation tools enable the prediction of function from a segment of a DNA sequence with significantly improved precision, which allows in-silico mutagenesis to interrogate the functional effect of SNP alleles. In this project, we explored the impact of top AD GWAS hits on chromatin functions and whether it will be altered by the genetic context (i.e., alleles of neighboring SNPs). Our results showed that highly correlated SNPs in the same LD block could have distinct impacts on downstream functions. Although some GWAS lead SNPs showed dominant functional effects regardless of the neighborhood SNP alleles, several other SNPs did exhibit enhanced loss or gain of function under certain genetic contexts, suggesting potential additional information hidden in the LD blocks.
    Language English
    Publishing date 2024-02-08
    Publishing country United States
    Document type Preprint
    DOI 10.21203/rs.3.rs-3871665/v1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Assessing the impact of entrepreneurial education activity on entrepreneurial intention and behavior: role of behavioral entrepreneurial mindset.

    Yan, Jingwen / Huang, Tian / Xiao, Yunxia

    Environmental science and pollution research international

    2022  Volume 30, Issue 10, Page(s) 26292–26307

    Abstract: This study explores the relationship between Entrepreneurship Education (EE) and Entrepreneurial Intentions (EI) using the Theory of Planned Behavior (TPB). From January through May of 2022, students from 10 Chinese institutions were surveyed using an ... ...

    Abstract This study explores the relationship between Entrepreneurship Education (EE) and Entrepreneurial Intentions (EI) using the Theory of Planned Behavior (TPB). From January through May of 2022, students from 10 Chinese institutions were surveyed using an online questionnaire. According to the research, students' EI scores rose significantly after participating in EE. In addition, students in China had a more significant impact on EI regarding factors like perceived feasibility and desirability. This study extends the body of knowledge about the connection between prior exposure and early intervention (EI) by demonstrating the beneficial effects of PE on EI. In addition, the results suggest that girls have lower EI than males, which is good news for gender equality. Lastly, the behavioral entrepreneur attitude has a favorable correlation with EI. Policymakers and university administrators might use the findings to understand better how and when extracurricular activities (EE) improve students' emotional intelligence (EI). A pioneering empirical study in a developing South-Asian setting shows the relevance of EE on EI among students at private universities. According to the study, EE generates EI, and entrepreneurial enthusiasm is crucial.
    MeSH term(s) Female ; Humans ; Male ; Asian People ; China ; Educational Status ; Intention ; Students ; Theory of Planned Behavior ; Entrepreneurship
    Language English
    Publishing date 2022-11-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1178791-0
    ISSN 1614-7499 ; 0944-1344
    ISSN (online) 1614-7499
    ISSN 0944-1344
    DOI 10.1007/s11356-022-23878-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: SCC-MPGCN: self-attention coherence clustering based on multi-pooling graph convolutional network for EEG emotion recognition.

    Zhao, Huijuan / Liu, Jingjin / Shen, Zhenqian / Yan, Jingwen

    Journal of neural engineering

    2022  Volume 19, Issue 2

    Abstract: The emotion recognition with electroencephalography (EEG) has been widely studied using the deep learning methods, but the topology of EEG channels is rarely exploited completely. In this paper, we propose a self-attention coherence clustering based on ... ...

    Abstract The emotion recognition with electroencephalography (EEG) has been widely studied using the deep learning methods, but the topology of EEG channels is rarely exploited completely. In this paper, we propose a self-attention coherence clustering based on multi-pooling graph convolutional network (SCC-MPGCN) model for EEG emotion recognition. The adjacency matrix is constructed based on phase-locking value to describe the intrinsic relationship between different EEG electrodes as graph signals. The graph Laplacian matrix is obtained from the adjacency matrix and then is fed into the graph convolutional layers to learn the generalized features. Moreover, we propose a novel graph coarsening method called SCC, using the coherence to cluster the nodes. The benefits are that the dimensionality of adjacency matrix can be reduced and the global information can be achieved from the raw data. Meanwhile, a MPGCN block is introduced to learn the generalized features of emotional states. The fully-connected layer and a softmax layer are adopted to derive the final classification results. We carry out the extensive experiments on DEAP dataset and the results show that the proposed method has better classification results than the state-of-the-art methods with the ten-fold cross-validation. And the model achieves the emotion recognition performance with a mean accuracy of 96.37%, 97.02%, 96.72% on valence, arousal, and dominance dimension, respectively.
    MeSH term(s) Attention ; Cluster Analysis ; Electroencephalography ; Emotions ; Neural Networks, Computer
    Language English
    Publishing date 2022-04-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2170901-4
    ISSN 1741-2552 ; 1741-2560
    ISSN (online) 1741-2552
    ISSN 1741-2560
    DOI 10.1088/1741-2552/ac6294
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Market failure and government failure in European debt crisis

    Yan Jingwen / Cai Zhishan / Zhou Rui

    E3S Web of Conferences, Vol 275, p

    2021  Volume 03025

    Abstract: This paper takes the “five European pig countries” in the European debt crisis as an example to analyze the event from the perspective of market failure and government failure. The main conclusions are as follows: the European debt crisis is the common ... ...

    Abstract This paper takes the “five European pig countries” in the European debt crisis as an example to analyze the event from the perspective of market failure and government failure. The main conclusions are as follows: the European debt crisis is the common product of market failure and government failure. Both sides should make great efforts to solve this problem. There is a long-term process to solve the European debt problem. Only by developing competitive industries and regaining international competitiveness is the effective way for euro zone countries to get rid of the predicament fundamentally.
    Keywords Environmental sciences ; GE1-350
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Study on the optimization path of SME financing services in the context of the epidemic

    Gu Weijian / Zhou Rui / Yan Jingwen

    E3S Web of Conferences, Vol 275, p

    2021  Volume 01034

    Abstract: The status of SMEs in the national economy has become increasingly prominent, but due to the factors like their small scale, imperfect information disclosure, the problem of financing difficulty and high financing has always restricted the health of SMEs ...

    Abstract The status of SMEs in the national economy has become increasingly prominent, but due to the factors like their small scale, imperfect information disclosure, the problem of financing difficulty and high financing has always restricted the health of SMEs in China. This report takes Wuhan as an example, which is the earliest affected by the COVID epidemic, starting from the new financing difficulties and the development of banking business of SMEs in Wuhan under the background of the epidemic, explores the methods to guide the three parties of banks, enterprises and governments to improve services, so as to better play the role of alleviating the new financing pressure of SMEs, and puts forward some suggestions, such as promoting the interaction of government and banks’ information, establishing an efficient punishment mechanism for enterprises’ dishonesty, and strengthening the supervision A series of countermeasures and suggestions, such as accurate product service innovation of fast financial institutions, guiding the docking of supply chain and bill financing platform. These suggestions have important reference significance and practical reference value for better adapting to the new characteristics of financing in the post epidemic era and alleviating the financing pressure of SMEs.
    Keywords Environmental sciences ; GE1-350
    Language English
    Publishing date 2021-01-01T00:00:00Z
    Publisher EDP Sciences
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article: Deciphering the tissue-specific functional effect of Alzheimer risk SNPs with deep genome annotation.

    Varathan, Pradeep / Xie, Linhui / He, Bing / Saykin, Andrew J / Nho, Kwangsik / Yan, Jingwen

    medRxiv : the preprint server for health sciences

    2023  

    Abstract: Alzheimer's disease (AD) is a highly heritable brain dementia, along with substantial failure of cognitive function. Large-scale genome-wide association studies (GWAS) have led to a significant set of SNPs associated with AD and related traits. GWAS hits ...

    Abstract Alzheimer's disease (AD) is a highly heritable brain dementia, along with substantial failure of cognitive function. Large-scale genome-wide association studies (GWAS) have led to a significant set of SNPs associated with AD and related traits. GWAS hits usually emerge as clusters where a lead SNP with the highest significance is surrounded by other less significant neighboring SNPs. Although functionality is not guaranteed with even the strongest associations in the GWAS, the lead SNPs have been historically the focus of the field, with the remaining associations inferred as redundant. Recent deep genome annotation tools enable the prediction of function from a segment of DNA sequence with significantly improved precision, which allows in-silico mutagenesis to interrogate the functional effect of SNP alleles. In this project, we explored the impact of top AD GWAS hits on the chromatin functions, and whether it will be altered by the genomic context (i.e., alleles of neighborhood SNPs). Our results showed that highly correlated SNPs in the same LD block could have distinct impact on the downstream functions. Although some GWAS lead SNPs showed dominating functional effect regardless of the neighborhood SNP alleles, several other ones do get enhanced loss or gain of function under certain genomic context, suggesting potential extra information hidden in the LD blocks.
    Language English
    Publishing date 2023-10-23
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2023.10.23.23297399
    Database MEDical Literature Analysis and Retrieval System OnLINE

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