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  1. Article: A Novel Method for Early Fatigue Damage Diagnosis in 316L Stainless Steel Formed by Selective Laser Melting Technology.

    Yan, Xiaoling / Tang, Xiujian

    Materials (Basel, Switzerland)

    2023  Volume 16, Issue 9

    Abstract: Early fatigue damage is an important factor affecting the service safety of 316L stainless steel parts formed by selective laser melting (SLM) technology. Nonlinear ultrasonic testing for early fatigue damage in SLM 316L stainless steel specimens was ... ...

    Abstract Early fatigue damage is an important factor affecting the service safety of 316L stainless steel parts formed by selective laser melting (SLM) technology. Nonlinear ultrasonic testing for early fatigue damage in SLM 316L stainless steel specimens was carried out. A new method for evaluation of early fatigue damage based on nonlinear ultrasonic testing was proposed. Empirical mode decomposition (EMD) was applied to the unsteady ultrasonic testing signal, and the signal was decomposed into multiple intrinsic mode functions (IMFs) that meet certain conditions; then, the specific IMF (ESI) containing the effective fatigue damage information was extracted. Lastly, fast Fourier transform (FFT) was applied to the specific IMF signal to obtain the required information to evaluate the damage in the measured part caused by fatigue. The results of nonlinear ultrasonic testing agreed well with transmission electron microscope experimental analysis and theoretical model of acoustic nonlinearity caused by dislocations. The change in nonlinear ultrasonic testing results reflected the generation and evolution of dislocation structure during the low-cycle fatigue regime of the SLM 316L stainless steel specimen and revealed the early fatigue damage mechanism of this metal part. Compared with the classical FFT method, the EMD-ESI-FFT method is more sensitive in identifying the early damage in SLM 316L stainless parts induced by fatigue loading, which is equivalent to improving the early fatigue damage identification and diagnosis ability and can better ensure the service safety of important metal parts.
    Language English
    Publishing date 2023-04-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma16093363
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: The Characterization of Fatigue Damage of 316L Stainless Steel Parts Formed by Selective Laser Melting with Harmonic Generation Technique.

    Qiao, Rui / Yan, Xiaoling

    Materials (Basel, Switzerland)

    2022  Volume 15, Issue 3

    Abstract: Fatigue damage is the main reason for the failure of parts formed by selective laser melting (SLM) technology. This paper presents a high-order, harmonic, and nonlinear ultrasonic testing system for monitoring the generation and evolution of fatigue ... ...

    Abstract Fatigue damage is the main reason for the failure of parts formed by selective laser melting (SLM) technology. This paper presents a high-order, harmonic, and nonlinear ultrasonic testing system for monitoring the generation and evolution of fatigue damage in SLM 316L stainless steel parts. The results demonstrate that the normalized ultrasonic, nonlinear coefficients show a significant dependence on the degree of fatigue damage of the tested specimen and that the normalized, ultrasonic, and nonlinear coefficients are effective in characterizing the degree of fatigue damage in SLM 316L stainless steel parts. Transmission electron microscope (TEM) and scanning electron microscope (SEM) analyses show that the variation in the normalized, ultrasonic, nonlinear coefficients reflect the generation and evolution process of dislocation and crack in the fatigue process of SLM 316L stainless steel specimens, and reveal the fatigue damage mechanism of SLM 316L stainless steel parts.
    Language English
    Publishing date 2022-01-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma15030718
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Research Progress in Nonlinear Ultrasonic Testing for Early Damage in Metal Materials.

    Yan, Xiaoling / Wang, Houpu / Fan, Xiaozhi

    Materials (Basel, Switzerland)

    2023  Volume 16, Issue 6

    Abstract: There are some limitations when conventional ultrasonic testing methods are used for testing early damage in metal parts. With the continuous development of acoustics and materials science, nonlinear ultrasonic nondestructive testing technology has been ... ...

    Abstract There are some limitations when conventional ultrasonic testing methods are used for testing early damage in metal parts. With the continuous development of acoustics and materials science, nonlinear ultrasonic nondestructive testing technology has been used for testing of early damage in metal materials. In order to better understand the basic theory and research progress of the nonlinear ultrasonic testing technology, the classical nonlinear ultrasonic theoretical models, including the dislocation monopole model, dislocation dipole model, precipitate-dislocation pinning model, and contact nonlinear ultrasonic theory-microcrack model, are analyzed in depth. This paper introduces the application and research progress of nonlinear ultrasonic detection technology, which is derived from different acoustic nonlinear effects, such as higher harmonic, wave mixing and modulation, sub-harmonic, resonance frequency spectrum analysis, and non-linear ultrasonic phased array imaging. The key technologies and problems are summarized to provide a reference for the further development and promotion of nonlinear ultrasonic non-destructive testing technology.
    Language English
    Publishing date 2023-03-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma16062161
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: What is the major driver of China's hospital medical expenditure growth? A decomposing analysis.

    Yan, Xiaoling / Liu, Yuanli / Rao, Keqin / Li, Jinlei

    BMJ open

    2022  Volume 12, Issue 2, Page(s) e048308

    Abstract: Objectives: This study aimed to quantify increases in the medical expenditures of public hospitals associated with changes in service use and prices, which could inform policy efforts to curb the future growth of hospital medical expenditures.: Design! ...

    Abstract Objectives: This study aimed to quantify increases in the medical expenditures of public hospitals associated with changes in service use and prices, which could inform policy efforts to curb the future growth of hospital medical expenditures.
    Design: Nationwide and provincial data regarding service volume, service price and intensity of public hospitals' outpatient and inpatient care from 2008 to 2018 were extracted from the China Health Statistical Yearbooks, and population size data were obtained from the 2019 China Statistical Yearbook.
    Methods: A decomposition analysis was performed to measure the relative effects of changes in service use (volume or its subcomponent factors) and service price and intensity on the increase in the inpatient and outpatient total medical expenditures of public hospitals from 2008 to 2018.
    Results: After adjusting for price inflation, the total medical expenditure of public hospitals increased by approximately threefold from 2008 to 2018. During this period, the increase in service volume was associated with 67.4% of the observed increase in the total medical expenditures in the inpatient sector and 57.2% of the observed increase in the total medical expenditures in the outpatient sector. Most of the service volume effect is due to an increase in the hospital utilisation rate. The growth in the utilisation rate was associated with 73.7% of the observed growth in the total medical expenditures in the inpatient sector and 60.3% of the observed growth in the total medical expenditures in the outpatient sector.
    Conclusion: Service use, rather than price, appears to be the major driver of increases in medical expenditures in Chinese hospitals. An important policy implication for China and other countries with similar drivers is that the effect of controlling price and intensity growth on containing medical costs could be limited and controlling service utilisation growth could be essential.
    MeSH term(s) China/epidemiology ; Costs and Cost Analysis ; Health Expenditures ; Hospitalization ; Hospitals, Public ; Humans
    Language English
    Publishing date 2022-02-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2020-048308
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Deciphering the Plastomic Code of Chinese Hog-Peanut (

    Xiang, Yi-Nan / Wang, Xiao-Qun / Ding, Lu-Lu / Bai, Xin-Yu / Feng, Yu-Qing / Qi, Zhe-Chen / Sun, Yong-Tao / Yan, Xiao-Ling

    Genes

    2024  Volume 15, Issue 1

    Abstract: The classification and phylogenetic relationships within the Phaseoleae tribe (Leguminosae) have consistently posed challenges to botanists. This study addresses these taxonomic intricacies, with a specific focus on the Glycininae subtribe, by conducting ...

    Abstract The classification and phylogenetic relationships within the Phaseoleae tribe (Leguminosae) have consistently posed challenges to botanists. This study addresses these taxonomic intricacies, with a specific focus on the Glycininae subtribe, by conducting a comprehensive analysis of the highly conserved plastome in
    MeSH term(s) Swine ; Animals ; Fabaceae/genetics ; Phylogeny ; Arachis ; Genomics ; China
    Language English
    Publishing date 2024-01-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527218-4
    ISSN 2073-4425 ; 2073-4425
    ISSN (online) 2073-4425
    ISSN 2073-4425
    DOI 10.3390/genes15010088
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Altered small-world and disrupted topological properties of functional connectivity networks in patients with nonarteritic anterior ischemic optic neuropathy.

    Wang, Hui / Yan, Xiaoling / Zhang, Qiuhuan / Wu, Qiong / Qiu, Lixin / Zhou, Jian / Guo, Pengde

    Clinical neurology and neurosurgery

    2023  Volume 236, Page(s) 108101

    Abstract: Background: Nonarteritic anterior ischemic optic neuropathy (NAION) is a disease of the optic nerve, but its effect on brain network topology is still unclear.This study aimed to investigate brain network alterations in NAION patients and to explore ... ...

    Abstract Background: Nonarteritic anterior ischemic optic neuropathy (NAION) is a disease of the optic nerve, but its effect on brain network topology is still unclear.This study aimed to investigate brain network alterations in NAION patients and to explore their relationship with functional impairment.
    Methods: Resting-state functional MRI data were collected from 23 NAION patients and 23 matched healthy control subjects.We used graph theory analysis to investigate the global and nodal network topological properties,and network-based statistical (NBS) methods were used to explore intergroup differences in functional connectivity (FC) strength.
    Results: Compared to the control group, NAION patients had lower global efficiency, normalized clustering coefficient and small-world values and higher characteristic path length (P < 0.05). In the hub distributions of functional networks, the NAION group had one hub region disappearing and four hub regions appearing in nodal degree centrality (Dc), and two hubs disappearing and one hub region appearing in nodal betweenness centrality (Bc). The NAION group also had enhanced brain FC primarily associated with the frontal, prefrontal, parietal lobes and cerebellum. Furthermore, the right temporal pole, superior temporal gyrus (r = -0.424), the right inferior temporal gyrus (r = -0.414), the right cerebellar lobule Ⅵ (r = 0.450), and the left cerebellar lobule crus Ⅰ (r = 0.584) were significantly correlated with clinical severity.
    Conclusion: NAION patients show disruption and redistribution of FC in specific regions of the brain network, which may be associated with visual impairment.
    MeSH term(s) Humans ; Optic Neuropathy, Ischemic/diagnostic imaging ; Magnetic Resonance Imaging/methods ; Brain/diagnostic imaging ; Brain Mapping/methods ; Temporal Lobe
    Language English
    Publishing date 2023-12-24
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 193107-6
    ISSN 1872-6968 ; 0303-8467
    ISSN (online) 1872-6968
    ISSN 0303-8467
    DOI 10.1016/j.clineuro.2023.108101
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Rapid intraoperative immunocytochemistry of central nervous system tumors.

    Zhang, Xuebin / Liu, Jiayu / Yan, Xiaoling

    International journal of clinical and experimental pathology

    2020  Volume 13, Issue 1, Page(s) 44–48

    Abstract: Intraoperative pathologic diagnosis for central nervous system (CNS) tumors is important to determine the neurosurgery procedure. But sometimes the differential diagnosis between glioma and lymphoma, or glioma and metastatic tumors is difficult for a ... ...

    Abstract Intraoperative pathologic diagnosis for central nervous system (CNS) tumors is important to determine the neurosurgery procedure. But sometimes the differential diagnosis between glioma and lymphoma, or glioma and metastatic tumors is difficult for a pathologist during a short time, especially when the specimen is small or the frozen section has ice crystals. Immunohistochemistry (IHC) is a very useful method for diagnosis, but the traditional immunohistochemical method is time-consuming and not suitable intraoperatively. In this study, we chose Cytokeratin-pan, GFAP, and LCA as three immunohistochemical indicators. Intraoperative IHC was done by Novodiax ihcDirect technology combined with Leica Bond auto-staining. Compared with the manual method recommended for the reagents (Novodiax ihcDirect), the results show that auto-staining has better stability and high reproducibility in coloration, which has broad prospects for future application.
    Language English
    Publishing date 2020-01-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2418306-4
    ISSN 1936-2625 ; 1936-2625
    ISSN (online) 1936-2625
    ISSN 1936-2625
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Optic neuritis of MOG-IgG-associated autoimmune disorders: a case report.

    Li, Tiantian / Zhou, Jian / Yan, Xiaoling / Duan, Ran / Zhu, Xiaobo

    BMC ophthalmology

    2021  Volume 21, Issue 1, Page(s) 24

    Abstract: Background: The diagnosis of immunoglobulin G serum antibodies to myelin oligodendrocyte glycoprotein (MOG-IgG) associated inflammatory demyelinating disorders can be confirmed by the presence of MOG-IgG, yet its general cut-off concentration had not ... ...

    Abstract Background: The diagnosis of immunoglobulin G serum antibodies to myelin oligodendrocyte glycoprotein (MOG-IgG) associated inflammatory demyelinating disorders can be confirmed by the presence of MOG-IgG, yet its general cut-off concentration had not yet to be defined. Whether it is significant that a seropositive lower titer level for MOG-IgG could cause disease is still unknown.
    Case presentation: A 55-year-old Chinese woman presented with acute optic neuritis manifestations in the left eye. MRI showed a left optic nerve demyelination image and a T2 hyperintensity at C7 vertebral segment without any extra specific lesions. AQP4-IgG was tested seronegative, while the MOG-IgG was positive, titer 1:10, by indirect immunofluorescence. Considering the lower concentration, we retested serum MOG-IgG after 6 months of steroid therapy, using cell-based assay, then we still got the same result which was also barely above the negative cut-off value. So, the clinical diagnose was "possible MOG-IgG-associated encephalomyelitis". The woman's condition improved by steroid therapy without relapse.
    Conclusions: Seropositive MOG-IgG, even at a lower level, could lead to an autoimmune inflammatory demyelination. In adults, it commonly presents as ON and myelitis. Although the patient had a considerable reaction, steroid therapy could not make MOG-IgG seronegative, instead, the antibody may persist even during remission and flare-ups can recur after steroid withdrawal. Therefore, a long-term follow-up is necessary to monitor the patient's prognosis.
    MeSH term(s) Adult ; Autoantibodies ; Autoimmune Diseases/diagnosis ; Autoimmune Diseases/drug therapy ; Evoked Potentials, Visual ; Female ; Humans ; Immunoglobulin G ; Middle Aged ; Neuromyelitis Optica ; Optic Neuritis/diagnosis ; Optic Neuritis/drug therapy ; Optic Neuritis/etiology
    Chemical Substances Autoantibodies ; Immunoglobulin G
    Language English
    Publishing date 2021-01-09
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2050436-6
    ISSN 1471-2415 ; 1471-2415
    ISSN (online) 1471-2415
    ISSN 1471-2415
    DOI 10.1186/s12886-020-01780-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Demyelinating disease

    YAN Xiao-ling

    Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 13, Iss 6, Pp 549-

    2013  Volume 549

    Keywords Neurology. Diseases of the nervous system ; RC346-429 ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Neurology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language Chinese
    Publishing date 2013-06-01T00:00:00Z
    Publisher Tianjin Huanhu Hospital
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Atypical meningioma

    YAN Xiao-ling

    Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 13, Iss 3, Pp 254-

    2013  Volume 254

    Keywords Neurology. Diseases of the nervous system ; RC346-429 ; Neurosciences. Biological psychiatry. Neuropsychiatry ; RC321-571 ; Internal medicine ; RC31-1245 ; Medicine ; R ; DOAJ:Neurology ; DOAJ:Medicine (General) ; DOAJ:Health Sciences
    Language Chinese
    Publishing date 2013-03-01T00:00:00Z
    Publisher Tianjin Huanhu Hospital
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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