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Article ; Online: Electrochemistry-assisted selective butadiene hydrogenation with water.

Yan, Yong-Qing / Chen, Ya / Wang, Zhao / Chen, Li-Hua / Tang, Hao-Lin / Su, Bao-Lian

2023 Volume 14, Issue 1, Page(s) 2106

Abstract: Alkene feedstocks are used to produce polymers with a market expected to reach 128.4 million metric tons by 2027. Butadiene is one of the impurities poisoning alkene polymerization catalysts and is usually removed by thermocatalytic selective ... ...

Abstract	Alkene feedstocks are used to produce polymers with a market expected to reach 128.4 million metric tons by 2027. Butadiene is one of the impurities poisoning alkene polymerization catalysts and is usually removed by thermocatalytic selective hydrogenation. Excessive use of H
Language	English
Publishing date	2023-04-13
Publishing country	England
Document type	Journal Article
ZDB-ID	2553671-0
ISSN	2041-1723 ; 2041-1723
ISSN (online)	2041-1723
ISSN	2041-1723
DOI	10.1038/s41467-023-37708-1
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Article ; Online: H

Yan, Yong-Qing / Wei, Zhao / Wang, Zhao / Li, Yao / Wang, Wei-Hao / Jiang, Bo / Su, Bao-Lian

Angewandte Chemie (International ed. in English)

2023 Volume 62, Issue 38, Page(s) e202309013

Abstract: ... ...

Abstract	H
Language	English
Publishing date	2023-08-17
Publishing country	Germany
Document type	Journal Article
ZDB-ID	2011836-3
ISSN	1521-3773 ; 1433-7851
ISSN (online)	1521-3773
ISSN	1433-7851
DOI	10.1002/anie.202309013
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Article ; Online: Effects of erythropoietin for precaution of steroid-induced femoral head necrosis in rats.

Yan, Yong-Qing / Pang, Qing-Jiang / Xu, Ren-Jie

BMC musculoskeletal disorders

2018 Volume 19, Issue 1, Page(s) 282

Abstract: Background: Steroids such as glucocorticoid have been widely used for their excellent anti-inflammatory, anti-immune, and anti-shock properties. However, the long-term use in high doses has been found to cause necrosis of femoral head and other serious ... ...

Abstract	Background: Steroids such as glucocorticoid have been widely used for their excellent anti-inflammatory, anti-immune, and anti-shock properties. However, the long-term use in high doses has been found to cause necrosis of femoral head and other serious adverse reactions. Thus, it is of great importance to safely use these medications on patients without inducing bone necrosis. Methods: In this preclinical study, we examined the effects of erythropoietin (EPO) to attenuate the induction of steroid-induced femoral bone necrosis using rats to build up the in-vivo models. Rats were randomly divided into three groups: negative control group (group A), disease group (group B), and EPO group (group C). 20 mg/kg methylprednisolone was administrated into group B and group C for 6 weeks with two intramuscular injections per week per rat. Group C was further given daily intraperitoneal injections of rHuEPO during this period. Group A received only injection of saline at the same schedule. 12 weeks after the initial drug administration, the rats' femoral tissues were harvested for HE staining, immunohistochemistry studies for PECAM-1(also CD31) expression and Western Blotting for VEGF expression. Results: Histology studies showed that compared with the disease group, EPO group had significant improvement and bone morphology being much closer to the negative control group. Immunohistochemical studies revealed that EPO group had statistically much more expression of PECAM-1 than the other groups did. Western Blot demonstrated that the EPO group had significantly higher VEGF expression than the disease group. Conclusion: Results suggested that simultaneous injection of EPO could partially prevent steroid-induced ANFH.
MeSH term(s)	Animals ; Disease Models, Animal ; Erythropoietin/pharmacology ; Female ; Femur Head/drug effects ; Femur Head/metabolism ; Femur Head/pathology ; Femur Head Necrosis/chemically induced ; Femur Head Necrosis/metabolism ; Femur Head Necrosis/pathology ; Femur Head Necrosis/prevention & control ; Male ; Methylprednisolone ; Platelet Endothelial Cell Adhesion Molecule-1/metabolism ; Rats, Sprague-Dawley ; Vascular Endothelial Growth Factor A/metabolism
Chemical Substances	EPO protein, human ; Platelet Endothelial Cell Adhesion Molecule-1 ; Vascular Endothelial Growth Factor A ; vascular endothelial growth factor A, rat ; Erythropoietin (11096-26-7) ; Methylprednisolone (X4W7ZR7023)
Language	English
Publishing date	2018-08-07
Publishing country	England
Document type	Journal Article
ZDB-ID	2041355-5
ISSN	1471-2474 ; 1471-2474
ISSN (online)	1471-2474
ISSN	1471-2474
DOI	10.1186/s12891-018-2208-2
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Article: [Finite element optimization analysis of minimally invasive screw treatment for Sanders typeⅡcalcaneal fracture].

Guo, Zong-Hui / Yan, Yong-Qing / Tang, Yin / Wang, Jun-Jie / Yang, Chang-Chun / Pang, Qing-Jiang

Zhongguo gu shang = China journal of orthopaedics and traumatology

2021 Volume 34, Issue 2, Page(s) 137–142

Abstract: Objective: To explore biomechanical characteristics of minimally invasive different screw fixations in treating Sanders typeⅡcalcaneal fractures.: Methods: Dicom data of calcaneus by CT scan were input into Mimics 21.0 software and Ansys15.0 software ...

Abstract	Objective: To explore biomechanical characteristics of minimally invasive different screw fixations in treating Sanders typeⅡcalcaneal fractures. Methods: Dicom data of calcaneus by CT scan were input into Mimics 21.0 software and Ansys15.0 software to construct three-dimensional finite element digital model of calcaneus;this model was input into UG NX 10.0 software, and calcaneus was cut according to Sanders classification to establish Sanders typeⅡ calcaneus model with posterior articular surface collapse;then simulated minimally invasive screw internal fixation after calcaneal fracture:a screw from posterior articular surface was used to outside-in fix sustentaculum tali, other 4 screws were used to fix calcaneus by different methods through calcaneal tuberosity, and 4 different calcaneal models were obtained. Under the same conditions, 4 types of internal fixation models were loaded respectively, and nonlinear finite element analysis was performed to calculate the stress distribution of different internal fixation models. Results: Under the same condition of loading, the model 3 had smaller displacement value, maximum calcaneus displacement value and maximum equivalent stress value of the screw than other three internal fixation models, and the stress was more dispersed. Conclusion: In minimally invasive screw internal fixation of calcaneus fracture, after 1 sustentaculum tali screw fixation, 2 screws crossed fix posterior articular surface from calcaneal tuberosity, 2 screws fix parallelly calcaneocuboid joint from calcaneal tuberosity are more suitable for biomechanical requirements, and could provide basic theory for clinical treatment.
MeSH term(s)	Bone Screws ; Calcaneus/surgery ; Finite Element Analysis ; Fracture Fixation, Internal ; Fractures, Bone/surgery ; Humans ; Treatment Outcome
Language	Chinese
Publishing date	2021-03-04
Publishing country	China
Document type	Journal Article
ISSN	1003-0034
ISSN	1003-0034
DOI	10.12200/j.issn.1003-0034.2021.02.008
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Article: [A clinical study on the stability of miniscrew anchorage in orthodontics].

Yan, Yong-Qing / Gao, Yi-Ming

Shanghai kou qiang yi xue = Shanghai journal of stomatology

2011 Volume 20, Issue 5, Page(s) 540–544

Abstract: Purpose: The aim of this retrospective study was to summarize the cases who used miniscrew anchorage and to evaluate the clinical factors influencing the stability of miniscrew.: Methods: The sample comprised 13 patients with 32 miniscrews, in whom ... ...

Abstract	Purpose: The aim of this retrospective study was to summarize the cases who used miniscrew anchorage and to evaluate the clinical factors influencing the stability of miniscrew. Methods: The sample comprised 13 patients with 32 miniscrews, in whom the design, occlusogingival position, alveolar position, loading opportunity, gingival condition were investigated to assess the factors related to stability. The data was analyzed by univariate analysis and multivariate analysis using SAS 10.0 software package. Results: The overall success rate was 90.6%. There was significant relationship between the patients' age and the stability of miniscrews (P=0.04). The success rate was 75% in adolescent patients, and 100% in adult patients. The osseointegration was affected by initial over-loading, but the long-term orthodontic loading (200g) was safe, if osseointegration was achieved. Perio-implant gingivitis, even the suppurative gingivitis (2 cases) didn't destroy the bone-implant interface. The success rate was independent on gender, occlusogingival position, jaw positioning, inserting times of the same miniscrew, and early loading. Conclusions: The primary stability is the crucial factor for long-term stability of the miniscrews.
MeSH term(s)	Adolescent ; Adult ; Bone Screws ; Dental Care ; Humans ; Orthodontic Anchorage Procedures ; Orthodontic Appliance Design ; Orthodontics ; Osseointegration ; Retrospective Studies
Language	Chinese
Publishing date	2011-10
Publishing country	China
Document type	English Abstract ; Journal Article
ZDB-ID	2269714-7
ISSN	1006-7248
ISSN	1006-7248
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Article: [A study on the stability of miniscrew on different loading time as orthodontic anchorage].

Zhu, Liang-yan / Yan, Yong-qing / Gao, Yi-ming

Shanghai kou qiang yi xue = Shanghai journal of stomatology

2011 Volume 20, Issue 6, Page(s) 590–594

Abstract: Purpose: To evaluate the stability of the miniscrew on different loading time as orthodontic anchorage.: Methods: 2 healthy adult male Beagle dogs were used in this study. 48 mini-implants were implanted into the maxilla and mandible of the dogs. The ...

Abstract	Purpose: To evaluate the stability of the miniscrew on different loading time as orthodontic anchorage. Methods: 2 healthy adult male Beagle dogs were used in this study. 48 mini-implants were implanted into the maxilla and mandible of the dogs. The miniscrews were divided into 8 different groups,1 group was loaded 0g as control group and the others were loaded 200g forces as experimental groups. 200g forces were loaded on the corresponding mini-implant anchorages immediately after implantation and at the time of 1w,2w,3w,4w,5w and 6w after implantation. The dogs were sacrificed at 12w after implantation. Histological progresses of implant-bone interfaces was examined with light microscope. Blue deposition and contact ratio were calculated and analyzed using SPSS13.0 software package. Results: Fibrous and osseous-integration was noted in the interface, there was no significant difference in bone deposition ratio and bone contact ratio. Conclusion: Different force loading time does not affect the stability of the mini-implant anchorage.
MeSH term(s)	Animals ; Bone Screws ; Dogs ; Male ; Mandible ; Maxilla ; Orthodontic Anchorage Procedures ; Osseointegration
Language	Chinese
Publishing date	2011-12
Publishing country	China
Document type	English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2269714-7
ISSN	1006-7248
ISSN	1006-7248
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Article: [Case-control study on effects of fracture of processus styloideus ulnae on prognosis after plate fixation for the treatment of distal radial fractures].

Yan, Yong-Qing / Zhang, Pei-Xun / Wang, Tian-Bing / Chen, Jian-Hai / Jiang, Bao-Guo

Zhongguo gu shang = China journal of orthopaedics and traumatology

2015 Volume 28, Issue 3, Page(s) 226–229

Abstract: Objective: To analyze effects of fracture of processus styloideus ulnae on prognosis in the treatment of distal radial fracture of type C according to AO classification.: Methods: This was a retrospective case-control study, and the information was ... ...

Abstract	Objective: To analyze effects of fracture of processus styloideus ulnae on prognosis in the treatment of distal radial fracture of type C according to AO classification. Methods: This was a retrospective case-control study, and the information was got ten through case evaluation and follow-up, including sex, age, patient satisfaction, Gartland & Werley score and radiographic score. There were 76 patient treated with open reduction and plate fixation in People's Hospital Affiliated to Peking University from July 2006 to July 2011. All the patients were divided into two groups: no combination with fracture of processus styloideus ulnae (group A, 56 cases), combination with fracture of processus styloideus ulnae (group B, 20 cases). The patients in group A and B were treated with open reduction and internal fixation; however the fracture of processus styloideus ulnae was not fixed. The indexes such as clinical data, bone grafting, joint movement, Gartland & Werley score and radiographic score were compared between two groups. Results: The ulnaris pain of patients in group B was more obvious than that in group A. The local VAS, palmar and dorsal flexion degree of wrist joint, motion VAS, patients satisfaction score, radial and ulnar deviation degree, pronation and supination of forearm degree, Gartland & Werley score and radiographic score were separately 0.1 ± 0.1, (51.1 ± 1.9)°, (60.2 ± 1.9)°, 0.6 ± 0.1 (23.1 ± 0.9)°, (28.7 ± 1.3)° (81.5 ± 2.6)°, (68.2 ± 2.7)° 1.9 ± 0.3, 89.6 ± 12.3 in group A; and separately 0.3 ± 0.3, (51.4 ± 2.3)°, (66.6 ± 1.7)°, 0.5 ± 0.2, (24.5 ± 2.0)°, (26.9 ± 1.8)°, (80.3 ± 2.5)°, (70.3 ± 3.7)°, 1.2 ± 0.4, 92.5 ± 7.5 in group B; there were no statistical differences in above indexes between two groups. Conclusion: Whether the distal radial fracture with a concomitant unrepaired ulnar styloid fracture or not exerts no influence on mainly outcomes including function, radiography and motion of the wrist.
MeSH term(s)	Bone Plates ; Case-Control Studies ; Female ; Fracture Fixation, Internal/methods ; Humans ; Male ; Middle Aged ; Prognosis ; Radius Fractures/surgery ; Retrospective Studies ; Ulna Fractures/surgery
Language	Chinese
Publishing date	2015-03
Publishing country	China
Document type	English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1003-0034
ISSN	1003-0034
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Article ; Online: Sheng-Mai-San attenuates contractile dysfunction and structural damage induced by chronic intermittent hypoxia in mice.

Mo, Wei-Lan / Chai, Cheng-Zhi / Kou, Jun-Ping / Yan, Yong-Qing / Yu, Bo-Yang

Chinese journal of natural medicines

2015 Volume 13, Issue 10, Page(s) 743–750

Abstract: Sheng-Mai-San (SMS), a well-known Chinese medicinal plant formula, is widely used for the treatment of cardiac diseases characterized by deficiency of Qi and Yin syndrome. A mouse chronic intermittent hypoxia (CIH) model was established to mimic the ... ...

Abstract	Sheng-Mai-San (SMS), a well-known Chinese medicinal plant formula, is widely used for the treatment of cardiac diseases characterized by deficiency of Qi and Yin syndrome. A mouse chronic intermittent hypoxia (CIH) model was established to mimic the primary clinical features of deficiency of Qi and Yin syndrome. Mice experienced CIH for 28 days (nadir 7% to peak 8% oxygen, 20 min per day), resulting in left ventricle (LV) dysfunction and structure abnormalities. After administration of SMS (0.55, 1.1, and 5.5 g·kg(-1)·d(-1)) for four weeks, improved cardiac function was observed, as indicated by the increase in the ejection fraction from the LV on echocardiography. SMS also preserved the structural integrity of the LV against eccentric hypotrophy, tissue vacuolization, and mitochondrial injury as measured by histology, electron microscopy, and ultrasound assessments. Mechanistically, the antioxidant effects of SMS were demonstrated; SMS was able to suppress mitochondrial apoptosis as indicated by the reduction of several pro-apoptotic factors (Bax, cytochrome c, and cleaved caspase-3) and up-regulation of the anti-apoptosis factor Bcl-2. In conclusion, these results demonstrate that SMS treatment can protect the structure and function of the LV and that the protective effects of this formula are associated with the regulation of the mitochondrial apoptosis pathway.
MeSH term(s)	Animals ; Antioxidants/pharmacology ; Antioxidants/therapeutic use ; Apoptosis ; Cardiomyopathies/drug therapy ; Cardiomyopathies/etiology ; Caspase 3/metabolism ; Cytochromes c/metabolism ; Disease Models, Animal ; Drug Combinations ; Drugs, Chinese Herbal/pharmacology ; Drugs, Chinese Herbal/therapeutic use ; Heart Ventricles/drug effects ; Heart Ventricles/pathology ; Heart Ventricles/physiopathology ; Hypoxia ; Male ; Mice, Inbred ICR ; Mitochondria/drug effects ; Mitochondria/metabolism ; Myocardium/pathology ; Oxygen/metabolism ; Phytotherapy ; Qi ; Up-Regulation ; Ventricular Dysfunction, Left/drug therapy ; Ventricular Dysfunction, Left/etiology ; bcl-2-Associated X Protein/metabolism
Chemical Substances	Antioxidants ; Drug Combinations ; Drugs, Chinese Herbal ; bcl-2-Associated X Protein ; fructus schizandrae, radix ginseng, radix ophiopogonis drug combination ; Cytochromes c (9007-43-6) ; Caspase 3 (EC 3.4.22.-) ; Oxygen (S88TT14065)
Language	English
Publishing date	2015-10
Publishing country	China
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2192577-X
ISSN	1875-5364 ; 2095-6975 ; 1672-3651
ISSN (online)	1875-5364
ISSN	2095-6975 ; 1672-3651
DOI	10.1016/S1875-5364(15)30074-1
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Zs.A 6113: Show issues

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Article: [Multi-center retrospective analysis of clinical and related sociologic characteristics of postoperative distal radius fracture patients].

Yan, Yong-qing / Zhang, Pei-xun / Wang, Tian-bing / Chen, Jian-hai / Jiang, Bao-guo

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences

2014 Volume 46, Issue 2, Page(s) 254–257

Abstract: Objective: To study clinical-related characteristics of sociology of postoperative distal radius fracture patients.: Methods: A multi-center retrospective research was conducted on the information of the case evaluation and follow-up, including the ... ...

Abstract	Objective: To study clinical-related characteristics of sociology of postoperative distal radius fracture patients. Methods: A multi-center retrospective research was conducted on the information of the case evaluation and follow-up, including the patients' gender, age, habits, history of chronic diseases, conditions of fracture, length of hospital stay and treatments. The epidemiology data were analyzed with SPSS15.0. Results: Of the entire 143 patients, 52 were male (average age: 41), and 91 were female (average age: 61). The different gender and age groups had significant distinction in the characteristics of injury. The length of hospital stay was influenced by the energy of injury. Conclusion: To reduce the damage or incidence of distal radius fracture, we should avoid falling, strengthen protection awareness, treat internal medicine diseases or osteoporosis and so on. The knowledge of characteristics of sociology and injury of distal radius fracture is beneficial to the prevention and treatment.
MeSH term(s)	Adult ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Postoperative Period ; Radius Fractures/epidemiology ; Retrospective Studies
Language	Chinese
Publishing date	2014-04-18
Publishing country	China
Document type	English Abstract ; Journal Article ; Multicenter Study
ISSN	1671-167X
ISSN	1671-167X
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Article: Protective Effects of Sheng-Mai-San on Right Ventricular Dysfunction during Chronic Intermittent Hypoxia in Mice.

Chai, Cheng-Zhi / Mo, Wei-Lan / Zhuang, Xian-Fei / Kou, Jun-Ping / Yan, Yong-Qing / Yu, Bo-Yang

Evidence-based complementary and alternative medicine : eCAM

2016 Volume 2016, Page(s) 4682786

Abstract: Right ventricular (RV) dysfunction and failure contribute to the increasing morbidity and mortality of cardiovascular diseases; however, current treatment strategies are grossly inadequate. Sheng-Mai-San (SMS) has been used to treat heart diseases for ... ...

Abstract	Right ventricular (RV) dysfunction and failure contribute to the increasing morbidity and mortality of cardiovascular diseases; however, current treatment strategies are grossly inadequate. Sheng-Mai-San (SMS) has been used to treat heart diseases for hundreds of years in China, and its protective effects on RV have not been observed. The present study was to investigate the protective effects of SMS aqueous extract on RV dysfunction in chronic intermittent hypoxia (CIH) mice model. The results showed that CIH mice model presented RV dysfunction and maladaptive compensation after 28-day-CIH and SMS treatment significantly reversed these changes. Diastolic function of RV was restored and systolic dysfunction was attenuated, including elevation of RV stroke volume and fractional shortening, as well as pulmonary circulation. Structurally, SMS treatment inhibited RV dilation, cardiomyocytes vacuolization, ultrastructure abnormalities, and the expression of cleaved caspase-3. Of importance, SMS showed remarkable antioxidant activity by decreasing the levels of malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE), increasing the levels of superoxide dismutase (SOD) and heme oxygenase-1 (HO-1), as well as inhibiting the overexpression of 3-NT in RV. Our results indicate that SMS preserve RV structure and function in CIH-exposed mice by involving regulation in both ROS and Reactive Nitrogen Species (RNS) production.
Language	English
Publishing date	2016-03-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	2171158-6
ISSN	1741-4288 ; 1741-427X
ISSN (online)	1741-4288
ISSN	1741-427X
DOI	10.1155/2016/4682786
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