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Article ; Online: VHL deficiency augments anthracycline sensitivity of clear cell renal cell carcinomas by down-regulating ALDH2

Yao-Hui Gao / Zhao-Xia Wu / Li-Qi Xie / Cai-Xia Li / Yu-Qin Mao / Yan-Tao Duan / Bing Han / San-Feng Han / Yun Yu / Hao-Jie Lu / Peng-Yuan Yang / Tian-Rui Xu / Jing-Lin Xia / Guo-Qiang Chen / Li-Shun Wang

Nature Communications, Vol 8, Iss 1, Pp 1-

2017  Volume 14

Abstract: The VHL tumour suppressor gene is lost in approximately 70% of clear cell renal cell carcinoma (ccRCC). In this study, the authors demonstrate that VHL loss in these tumours augments anthracyclines chemotherapy by down-regulation of ALDH2. ...

Abstract The VHL tumour suppressor gene is lost in approximately 70% of clear cell renal cell carcinoma (ccRCC). In this study, the authors demonstrate that VHL loss in these tumours augments anthracyclines chemotherapy by down-regulation of ALDH2.
Keywords Science ; Q
Language English
Publishing date 2017-06-01T00:00:00Z
Publisher Nature Portfolio
Document type Article ; Online
Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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