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  1. Article ; Online: Clinical characteristics of rosacea in perimenopausal women.

    Yang, Fengjuan / Wang, Lian / Jiang, Xian

    Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)

    2024  Volume 30, Issue 1, Page(s) e13542

    MeSH term(s) Female ; Humans ; Perimenopause ; Rosacea/diagnosis
    Language English
    Publishing date 2024-01-14
    Publishing country England
    Document type Letter
    ZDB-ID 1229160-2
    ISSN 1600-0846 ; 0909-752X ; 1397-1344
    ISSN (online) 1600-0846
    ISSN 0909-752X ; 1397-1344
    DOI 10.1111/srt.13542
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Causal relationship between gut microbiota and rosacea: a two-sample Mendelian randomization study.

    Li, Jiaqi / Yang, Fengjuan / Liu, Yuling / Jiang, Xian

    Frontiers in medicine

    2024  Volume 11, Page(s) 1322685

    Abstract: Background: Rosacea, a chronic inflammatory skin condition affecting millions worldwide, is influenced by complex interactions between genetic and environmental factors. Although gut microbiota's role in skin health is well-acknowledged, definitive ... ...

    Abstract Background: Rosacea, a chronic inflammatory skin condition affecting millions worldwide, is influenced by complex interactions between genetic and environmental factors. Although gut microbiota's role in skin health is well-acknowledged, definitive causal links between gut microbiota and rosacea remain under-explored.
    Methods: Using a two-sample Mendelian randomization (MR) design, this study examined potential causal relationships between gut microbiota and rosacea. Data was sourced from the largest Genome-Wide Association Study (GWAS) for gut microbiota and the FinnGen biobank for rosacea. A total of 2078 single nucleotide polymorphisms (SNPs) associated with gut microbiota were identified and analyzed using a suite of MR techniques to discern causal effects.
    Results: The study identified a protective role against rosacea for two bacterial genera: phylum Actinobacteria and genus Butyrivibrio. Furthermore, 14 gut microbiota taxa were discovered to exert significant causal effects on variant categories of rosacea. While none of these results met the strict False Discovery Rate correction threshold, they retained nominal significance. MR outcomes showed no pleiotropy, with homogeneity observed across selected SNPs. Directionality tests pointed toward a robust causative path from gut microbiota to rosacea.
    Conclusion: This study provides compelling evidence of the gut microbiota's nominal causal influence on rosacea, shedding light on the gut-skin axis's intricacies and offering potential avenues for therapeutic interventions in rosacea management. Further research is warranted to validate these findings and explore their clinical implications.
    Language English
    Publishing date 2024-03-22
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2024.1322685
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Evidence for no genetic causal association between skin response to sun exposure and systemic lupus erythematosus: A Mendelian randomization study in Europeans and East Asians.

    Yang, Fengjuan / Li, Jiaqi / Jiang, Xian

    Journal of the European Academy of Dermatology and Venereology : JEADV

    2024  

    Language English
    Publishing date 2024-02-19
    Publishing country England
    Document type Letter
    ZDB-ID 1128828-0
    ISSN 1468-3083 ; 0926-9959
    ISSN (online) 1468-3083
    ISSN 0926-9959
    DOI 10.1111/jdv.19843
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: A retrospective study on VISIA of telangiectasia network in 378 cases of rosacea of the upper eyelid.

    Yang, Fengjuan / Song, Deyu / Wang, Lian / Jiang, Xian

    Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)

    2023  Volume 29, Issue 9, Page(s) e13411

    Language English
    Publishing date 2023-09-27
    Publishing country England
    Document type Letter
    ZDB-ID 1229160-2
    ISSN 1600-0846 ; 0909-752X ; 1397-1344
    ISSN (online) 1600-0846
    ISSN 0909-752X ; 1397-1344
    DOI 10.1111/srt.13411
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The MYB transcription factor SmMYB113 directly regulates ethylene-dependent flower abscission in eggplant.

    Chen, Jing / Jiang, Senlin / Yang, Guobin / Li, Lujun / Li, Jing / Yang, Fengjuan

    Plant physiology and biochemistry : PPB

    2024  Volume 209, Page(s) 108544

    Abstract: Flower abscission is an important developmental process that can significantly reduce the yield of horticultural plants. We previously reported that SmMYB113 is a key transcription factor promoting anthocyanin biosynthesis and improve fruit quality. ... ...

    Abstract Flower abscission is an important developmental process that can significantly reduce the yield of horticultural plants. We previously reported that SmMYB113 is a key transcription factor promoting anthocyanin biosynthesis and improve fruit quality. However, the overexpression of SmMYB113 in eggplant increased flower drop rate and reduced fruit yield. Here, we elucidate the regulatory mechanisms of SmMYB113 on flower abscission in eggplant. RNA-seq analysis indicated that the regulation of flower abscission by SmMYB113 was associated with altered expression of genes related to ethylene biosynthesis and signal transduction, including ethylene biosynthetic genes SmACS1, SmACS8 and SmACO4. Then, the ethylene content in flowers and the function of ethephon (ETH, which promotes fruit ripening) and 1-Methylcyclopropene (1-MCP, which acts as an ethylene perception inhibitor) were analyzed, which revealed that SmMYB113 directly regulates ethylene-dependent flower abscission. Yeast one-hybrid and dual-luciferase assays revealed that SmMYB113 could directly bind to the promoters of SmACS1, SmACS8, and SmACO4 to activate their expression. Through construction of a yeast two-hybrid (Y2H) screening library, the protein SmERF38 was found to interact with SmMYB113, and verified by Y2H, bimolecular fluorescence complementation (BiFC), and luciferase complementation assay. Furthermore, dual-luciferase assays showed that SmERF38 enhanced the role of SmMYB113 on the promoters of SmACS1. Our results provided new insight into the molecular mechanism of flower abscission in eggplant.
    MeSH term(s) Transcription Factors/genetics ; Transcription Factors/metabolism ; Solanum melongena/genetics ; Solanum melongena/metabolism ; Saccharomyces cerevisiae/metabolism ; Gene Expression Regulation, Plant ; Ethylenes/metabolism ; Flowers/metabolism ; Luciferases/genetics ; Luciferases/metabolism ; Plant Proteins/genetics ; Plant Proteins/metabolism
    Chemical Substances Transcription Factors ; ethylene (91GW059KN7) ; Ethylenes ; Luciferases (EC 1.13.12.-) ; Plant Proteins
    Language English
    Publishing date 2024-03-19
    Publishing country France
    Document type Journal Article
    ZDB-ID 742978-2
    ISSN 1873-2690 ; 0981-9428
    ISSN (online) 1873-2690
    ISSN 0981-9428
    DOI 10.1016/j.plaphy.2024.108544
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Assessment of sulfamethoxazole removal by three wetland plant species under hydroponic conditions: uptake, accumulation, and physiological responses.

    Li, Li / Yang, Fengjuan / A, Dan / Jiang, Yu / Chen, Minling / Zhang, Xiaomeng / Yang, Yang

    International journal of phytoremediation

    2024  , Page(s) 1–9

    Abstract: Plants play a crucial role as a removal pathway in constructed wetlands, demonstrating the ability to absorb and tolerate antibiotics from wastewater. However, the specific contribution of plants in this regard has not yet to be sufficiently established. ...

    Abstract Plants play a crucial role as a removal pathway in constructed wetlands, demonstrating the ability to absorb and tolerate antibiotics from wastewater. However, the specific contribution of plants in this regard has not yet to be sufficiently established. To gain a more comprehensive insight into the associated processes, we selected three common wetland plant species,
    Language English
    Publishing date 2024-03-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2055357-2
    ISSN 1549-7879 ; 1522-6514
    ISSN (online) 1549-7879
    ISSN 1522-6514
    DOI 10.1080/15226514.2024.2324038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Effect of COVID-19 and Face Masks on the Condition of Rosacea - A Retrospective Analysis of 87 Patients.

    Zhang, Ting / Liu, Xu / Yang, Fengjuan / Xu, Yuanyuan / Jiang, Xian

    Clinical, cosmetic and investigational dermatology

    2023  Volume 16, Page(s) 2855–2862

    Abstract: Introduction: The pathogenesis of COVID-19 includes systemic immune activation and endothelial dysfunction, which is closely related to the pathogenesis of rosacea. In order to investigate the influence of COVID-19 infection on the condition of rosacea ... ...

    Abstract Introduction: The pathogenesis of COVID-19 includes systemic immune activation and endothelial dysfunction, which is closely related to the pathogenesis of rosacea. In order to investigate the influence of COVID-19 infection on the condition of rosacea patients, we retrospectively investigated the impact of COVID-19 infection and COVID-19-related masks on rosacea patients.
    Methods: We collected the basic information from rosacea patients who had a long-term follow-up at West China Hospital of Sichuan University. Between January 2023 and March 2023, we recruited 87 rosacea patients for this survey.
    Results: Our results showed that COVID-19 infection could aggravate the condition of rosacea patients, and the change in the symptoms was not related to fever, temperature, antipyretics use, and vaccination. In addition, we observed a significant association between the type of mask worn by rosacea patients and exacerbation, while the duration of mask usage did not exhibit a similar relationship.
    Discussion: Considering the ongoing global utilization of masks due to the COVID-19 pandemic and the possible recurrence of COVID-19 infection, dermatologists should monitor the condition of rosacea patients infected with COVID-19 and adjust the treatment regimens accordingly.
    Language English
    Publishing date 2023-10-13
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2494852-4
    ISSN 1178-7015
    ISSN 1178-7015
    DOI 10.2147/CCID.S429099
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Four Cases of Port-Wine Birthmark Treated with Hematoporphyrin Monomethyl Ether-Mediated Photodynamic Therapy After Radioactive Nuclide Patch Therapy.

    Liu, Xu / Yang, Lihua / Zhang, Qian / Yang, Fengjuan / Jiang, Xian

    Clinical, cosmetic and investigational dermatology

    2023  Volume 16, Page(s) 1667–1675

    Abstract: Port-wine birthmark (PWB) are congenital vascular malformations that commonly occur on the face and neck, with an incidence of 0.3-0.5% in the general population, causing significant negative psychological effects and economic burden to patients. ... ...

    Abstract Port-wine birthmark (PWB) are congenital vascular malformations that commonly occur on the face and neck, with an incidence of 0.3-0.5% in the general population, causing significant negative psychological effects and economic burden to patients. Nevertheless, amidst the plethora of different treatment methods for PWB, choosing the option that best suits the patient's need can be a challenge. In recent years, traditional treatment methods for PWB have been replaced by new therapies, and radioactive nuclide patch therapy is one of them. A panel of experts sought to describe herein 4 clinical cases, illustrating the PDT can demonstrate good precision and efficacy in the treatment of PWB. The research findings show the 4 patients in this group had a history of treatment with radioactive isotope patches. After 2-3 sessions of HMME-PDT, all cases achieved satisfactory results, the color of the red skin lesions significantly faded, and the area of the lesions decreased noticeably. Superficial tissue ultrasound showed a reduction in lesion thickness before and after treatment. In summary, for cases where the efficacy of PWB treatment with radioactive isotope patches is inadequate, Photodynamic therapy (PDT) can be used as a treatment reference.
    Language English
    Publishing date 2023-06-28
    Publishing country New Zealand
    Document type Case Reports
    ZDB-ID 2494852-4
    ISSN 1178-7015
    ISSN 1178-7015
    DOI 10.2147/CCID.S418019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Response of photomorphogenesis and photosynthetic properties of sweet pepper seedlings exposed to mixed red and blue light.

    Li, Yan / Xin, Guofeng / Shi, Qinghua / Yang, Fengjuan / Wei, Min

    Frontiers in plant science

    2023  Volume 13, Page(s) 984051

    Abstract: Various light spectra, especially red (RL) and blue light (BL), have great effects on physiological processes and growth of plants. Previously, we revealed that the plant photomorphogenesis and photosynthesis of sweet pepper was significantly altered ... ...

    Abstract Various light spectra, especially red (RL) and blue light (BL), have great effects on physiological processes and growth of plants. Previously, we revealed that the plant photomorphogenesis and photosynthesis of sweet pepper was significantly altered under BL or mixed RL and BL. The present study aimed to elucidate how mixed RL and BL influences plant photosynthesis during photomorphogenesis. We examined the growth, plant morphology, photosynthetic response of sweet pepper seedlings under monochromatic RL, BL, different ratios of mixed RL and BL (9R1B, 6R1B, 3R1B, 1R1B, 1R3B) with the same photosynthetic photon flux density of 300 μmol·m
    Language English
    Publishing date 2023-02-07
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2613694-6
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2022.984051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Mesotherapy-Induced Cutaneous Foreign Body-Type Granulomatous Reaction in the Face Treated with Minocycline: Case Report and Literature Review.

    Zhang, Qian / Yang, Lihua / Yang, Fengjuan / Liu, Lian / Jiang, Xian

    Clinical, cosmetic and investigational dermatology

    2023  Volume 16, Page(s) 861–867

    Abstract: Mesotherapy is a popular treatment that delivers substances deep into the skin but induces foreign body-type granulomatous reactions. However, such reactions caused by unauthorized use of topical tranexamic acid products in mesotherapy have never been ... ...

    Abstract Mesotherapy is a popular treatment that delivers substances deep into the skin but induces foreign body-type granulomatous reactions. However, such reactions caused by unauthorized use of topical tranexamic acid products in mesotherapy have never been reported before. We herein demonstrated a case of a 33-year-old woman with multiple mesotherapy-induced foreign body-type granulomas disseminated across her face. The patient was diagnosed with echo-color Doppler (ECD) and successfully treated with medications including minocycline hydrochloride. Then, we reviewed the differential diagnosis and current treatment for foreign body-type granulomatous reaction.
    Language English
    Publishing date 2023-04-03
    Publishing country New Zealand
    Document type Case Reports
    ZDB-ID 2494852-4
    ISSN 1178-7015
    ISSN 1178-7015
    DOI 10.2147/CCID.S403601
    Database MEDical Literature Analysis and Retrieval System OnLINE

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