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  1. Article ; Online: A homologous series of α-glucans from Hemicentrotus pulcherrimus and their immunomodulatory activity.

    Shang, Zhipeng / Jiang, Yan / Yang, Fuhao / Wu, Ke / Zheng, Gaoliang / Lin, Yexi / Wang, Chunhua / Xin, Wenyu / Zhao, Feng

    International journal of biological macromolecules

    2024  Volume 260, Issue Pt 2, Page(s) 129657

    Abstract: Seven macromolecular polysaccharides (HPP-2S-HPP-8S) were purified from the gonads of sea urchin Hemicentrotus pulcherrimus. They were characterized as α-glucan homologues, sharing the same α-1,4-glucan backbone substituted at C-6 positions by glucose ... ...

    Abstract Seven macromolecular polysaccharides (HPP-2S-HPP-8S) were purified from the gonads of sea urchin Hemicentrotus pulcherrimus. They were characterized as α-glucan homologues, sharing the same α-1,4-glucan backbone substituted at C-6 positions by glucose with HPP-1S that occurs as the major polysaccharide in H. pulcherrimus, while with higher degrees of branching, and additionally possessing minor amounts of mannose and ribose. The branching degree and amounts of non-glucose branches showed a generally increasing tendency across HPP-2S - HPP-8S. These polysaccharides exhibited significant macrophage-activating effects by augmenting the secretion of NO, TNF-α and IL-6, which probably involves the activation of NF-κB and MAPKs signaling pathways. Notably, the polysaccharides with a higher degree of branching exhibited markedly enhanced immunomodulatory capacity with a lowest effective concentration of 1.95 μg/mL. This work provides new cases of bioactive α-glucans and reveals their potential application as immunomodulating agents.
    MeSH term(s) Animals ; Glucans ; Hemicentrotus ; Signal Transduction ; Polysaccharides ; Sea Urchins
    Chemical Substances Glucans ; Polysaccharides
    Language English
    Publishing date 2024-01-20
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2024.129657
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Low-Threshold, Multiple High-Order Harmonics Fiber Laser Employing Cr

    Xu, Nannan / Shang, Xinxin / Sun, Shuo / Yang, Fuhao / Fan, Weiyu / Zhang, Huanian / Li, Dengwang

    Nanomaterials (Basel, Switzerland)

    2023  Volume 13, Issue 6

    Abstract: Abundant research findings have proved the value of two-dimensional (2D) materials in the study of nonlinear optics in fiber lasers. However, there remains two problems: how to reduce the start-up threshold, and how to improve the damage threshold, of ... ...

    Abstract Abundant research findings have proved the value of two-dimensional (2D) materials in the study of nonlinear optics in fiber lasers. However, there remains two problems: how to reduce the start-up threshold, and how to improve the damage threshold, of fiber lasers based on 2D materials. A 15.1 mW low-threshold mode-locked fiber laser, based on a Cr
    Language English
    Publishing date 2023-03-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano13061038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Preparation of a recyclable novel thermoresponsive affinity copolymer and its application towards ε-polylysine purification

    Yang, Fuhao / Wan, Junfen / Cao, Xuejun

    Process biochemistry. 2020 Jan., v. 88

    2020  

    Abstract: Thermo-responsive polymers have great potential for industrial applications of bio-separation and purification. However, the poor affinity and low recovery of thermoresponsive copolymers are the main factors limiting their large-scale application. In ... ...

    Abstract Thermo-responsive polymers have great potential for industrial applications of bio-separation and purification. However, the poor affinity and low recovery of thermoresponsive copolymers are the main factors limiting their large-scale application. In this paper, a recyclable thermoresponsive affinity copolymer (PNHM-IDA-Ni²⁺) was prepared by immobilizing nickel ions (Ni²⁺) on copolymer PNHM, and PNHM-IDA-Ni²⁺ was applied to the purification of ε-polylysine. The lower critical solution temperature (LCST) of PNHM and PNHM-IDA-Ni²⁺ were 31.0 °C and 34.0 °C, respectively. Additionally, the recoveries of both copolymers were over 95.0%. The main parameters, such as pH were investigated to optimize the adsorption conditions. In addition, the Langmuir and Freundlich adsorption models were used to predict the maximum adsorption capacity of ε-polylysine. The results of the affinity precipitation demonstrated that the maximum adsorption capacity was 42.9 mg/g, and the adsorption was considered to follow the mono-layer model. The thermodynamic parameters (ΔG⁰, ΔH⁰ and ΔS⁰) of the ε-polylysine adsorption indicated that the adsorption was spontaneous and exothermic. The maximum elution recovery (93.5%) was achieved at pH 5.0 with 0.2 M imidazole. The results of tricine-SDS-PAGE and HPLC (Purity: increased from 84% to 99%) showed that the ε-polylysine was well separated from the crude extract by using the affinity copolymer PNHM-IDA-Ni²⁺.
    Keywords adsorption ; composite polymers ; heat production ; high performance liquid chromatography ; imidazole ; industrial applications ; ions ; models ; nickel ; pH ; temperature
    Language English
    Dates of publication 2020-01
    Size p. 204-212.
    Publishing place Elsevier Ltd
    Document type Article
    ISSN 1359-5113
    DOI 10.1016/j.procbio.2019.09.003
    Database NAL-Catalogue (AGRICOLA)

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  4. Article: MOF Template-Derived Carbon Shell-Embedded CoP Hierarchical Nanosheet as Bifunctional Catalyst for Overall Water Splitting.

    Liu, Mei-Jun / Yang, Fu-Hao / Mei, Ji-Cheng / Guo, Xu / Wang, Hua-Yang / He, Meng-Yao / Yao, Yu-Ang / Zhang, Hai-Feng / Liu, Cheng-Bin

    Nanomaterials (Basel, Switzerland)

    2023  Volume 13, Issue 17

    Abstract: The design of earth-abundant and highly efficient bifunctional electrocatalysts for hydrogen evolution and oxygen evolution reactions (HER/OER) is crucial for hydrogen production through overall water splitting. Herein, we report a novel nanostructure ... ...

    Abstract The design of earth-abundant and highly efficient bifunctional electrocatalysts for hydrogen evolution and oxygen evolution reactions (HER/OER) is crucial for hydrogen production through overall water splitting. Herein, we report a novel nanostructure consisting of vertically oriented CoP hierarchical nanosheet arrays with in situ-assembled carbon skeletons on a Ti foil electrode. The novel Zeolitic Imidazolate Framework-67 (ZIF-67) template-derived hierarchical nanosheet architecture effectively improved electrical conductivity, facilitated electrolyte transport, and increased the exposure of the active sites. The obtained bifunctional hybrid exhibited a low overpotential of 72 mV at 10 mA cm
    Language English
    Publishing date 2023-08-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano13172421
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  5. Article ; Online: Generation of bright-dark solitons in an Er-doped fiber laser employing InSb as a saturable absorber.

    Tang, Shouqian / Sheng, Qiuyan / Wang, Yanjuan / Chen, Si / Ye, Faming / Yang, Fuhao / Sun, Shuo / Sui, Zhiqi / Bai, Caixun / Lu, Cheng / Fu, Shenggui / Zhang, Huanian / Zhang, Wenfei / Wang, Guomei

    Applied optics

    2023  Volume 62, Issue 8, Page(s) 1921–1926

    Abstract: In this paper, an indium antimonide (InSb) saturable absorber (SA) was successfully fabricated. The saturable absorption properties of the InSb SA were studied, and they show a modulation depth and a saturable intensity of 5.17% and 9 ... ...

    Abstract In this paper, an indium antimonide (InSb) saturable absorber (SA) was successfully fabricated. The saturable absorption properties of the InSb SA were studied, and they show a modulation depth and a saturable intensity of 5.17% and 9.23
    Language English
    Publishing date 2023-05-03
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.478859
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Passively mode-locked Er-doped fiber laser based on a ferromagnetic insulator Cr

    Yang, Fuhao / Sun, Shuo / Chen, Si / Wang, Yanjuan / Sui, Zhiqi / Zhu, Mingxiao / Hong, Zhifeng / Xu, Jianghao / Tang, Shouqian / Lu, Cheng / Wang, Guomei / Fu, Shenggui / Chen, Xiaohan / Zhang, Huanian / Zhang, Wenfei

    Applied optics

    2022  Volume 61, Issue 4, Page(s) 898–903

    Abstract: In our work, a new-type, to the best of our knowledge, ferromagnetic insulator and its nonlinear optical absorption characteristics and related ultrafast modulation applications were investigated. ...

    Abstract In our work, a new-type, to the best of our knowledge, ferromagnetic insulator and its nonlinear optical absorption characteristics and related ultrafast modulation applications were investigated.
    Language English
    Publishing date 2022-02-21
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.448502
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Generation of bright-dark soliton pairs based on a ferromagnetic insulator Cr

    Sui, Zhiqi / Zhu, Mingxiao / Chen, Si / Yang, Fuhao / Wang, Yanjuan / Sun, Shuo / Hong, Zhifeng / Fan, Weiyu / Zhang, Wenfei / Zhang, Huanian / Chen, Xiaohan / Wang, Guomei / Fu, Shenggui

    Applied optics

    2022  Volume 61, Issue 11, Page(s) 3254–3259

    Abstract: In this work, a saturable absorber (SA) based ... ...

    Abstract In this work, a saturable absorber (SA) based on
    Language English
    Publishing date 2022-04-26
    Publishing country United States
    Document type Journal Article
    ISSN 1539-4522
    ISSN (online) 1539-4522
    DOI 10.1364/AO.453675
    Database MEDical Literature Analysis and Retrieval System OnLINE

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