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Article ; Online: Psychometric Testing of the Newly Developed Competence Scale for Clinical Nurses.

Kao, Chia-Chan / Chao, Hsiu-Ling / Liu, Yi-Hui / Pan, I-Ju / Yang, Li-Hui / Chen, Wan-I

2022 Volume 30, Issue 2, Page(s) e198

Abstract: Background: Nursing competence is an essential element in ensuring high-quality nursing care and positive patient outcomes. Valid and reliable assessment tools for assessing nurse competence are needed to help nurse supervisors measure whether nurses ... ...

Abstract	Background: Nursing competence is an essential element in ensuring high-quality nursing care and positive patient outcomes. Valid and reliable assessment tools for assessing nurse competence are needed to help nurse supervisors measure whether nurses are performing their job well and to provide a baseline for improving the competences of nurses. Purpose: This study was designed to develop and psychometrically validate the Competence Scale for Clinical Nurses (CSCN). Methods: The CSCN was developed in three steps: (a) generalize assessment items from nursing competence-related scales and a review of the relevant literature, (b) determine the content validity of the developed scale, and (c) psychometrically test the developed scale. Five hundred nurses were recruited from a medical center in southern Taiwan. Exploratory and confirmatory factor analyses were executed to analyze construct validity and internal consistency reliability. Results: The scale-content validity index was .87, as determined by five experts. Two thirds (63.29%) of the variance was explained by three factors: basic care skills (nine items), being dedicated to work (five items), and patient-centered and ethical considerations (four items). A second-order confirmatory factor analysis indicated that the data fit the model well. The Cronbach's alpha coefficients for each of the three factors and the total scale were .84-.91. Conclusions/implications for practice: The 18-item CSCN is a feasible and time-efficient tool for assessing competence in clinical nurses. Nursing supervisors may use this tool to explore nurses' competency and routinely track the effect of continuing education on competence. Continuous evaluation of nurses' clinical-based competence using the CSCN is recommended.
MeSH term(s)	Clinical Competence ; Factor Analysis, Statistical ; Humans ; Morals ; Psychometrics ; Reproducibility of Results
Language	English
Publishing date	2022-02-21
Publishing country	China (Republic : 1949- )
Document type	Journal Article ; Review
ZDB-ID	2277010-0
ISSN	1948-965X ; 1682-3141
ISSN (online)	1948-965X
ISSN	1682-3141
DOI	10.1097/jnr.0000000000000472
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Article: Electro-activation of peroxymonosulfate by a graphene oxide/iron oxide nanoparticle-doped Ti4O7 ceramic membrane: mechanism of singlet oxygen generation in the removal of 1,4-dioxane

Li, Wei / Xiao, Runlin / Lin, Hui / Yang, Kui / He, Kuanchang / Yang, Li-Hui / Pu, Mengjie / Li, Mengyun / Lv, Sihao

Journal of hazardous materials. 2022 Feb. 15, v. 424

2022

Abstract: Electro-activation of peroxymonosulfate (PMS) has been widely investigated for the degradation of organic pollutants. Herein, we employ graphene oxide (GO)/Fe₃O₄ nanoparticles (NPs) doped into a Ti₄O₇ reactive electrochemical membrane through strong ... ...

Abstract	Electro-activation of peroxymonosulfate (PMS) has been widely investigated for the degradation of organic pollutants. Herein, we employ graphene oxide (GO)/Fe₃O₄ nanoparticles (NPs) doped into a Ti₄O₇ reactive electrochemical membrane through strong chemical bonding as the cathode to activate PMS for the degradation of 1,4-dioxane (1,4-D). The strong chemical interaction between GO, Fe₃O₄-NPs, and Ti₄O₇ via Fe–O---GO---O–Ti bonds enhances the electron-transfer efficiency and provides catalytically active sites that boost the electro-activation of PMS. As a result, the 1,4-D oxidation rate of the GO/Fe₃O₄-NPs@Ti₄O₇ REM cathode is ~3 times higher (7.21 × 10⁻³ min⁻¹) than those of other Ti₄O₇ ceramic membranes, and ¹O₂ plays a key role (59.9%) in the degradation of 1,4-D. The ¹O₂ generation mechanism in the electro-activation process of PMS was systematically investigated, and we claimed that ¹O₂ is mainly generated from the precursors H₂O₂ and O₂•–/HO₂• rather than by O₂ or •OH, as has been reported in previous studies. A flow-through mode test in the PMS electro-activation system is firstly reported, and the 1,4-D decay efficiency is 7.1 times higher than that obtained by a flow-by mode, showing that an improved PMS mass transfer efficiency enhances the conversion to reactive oxygen species.
Keywords	cathodes ; ceramics ; electrochemistry ; electron transfer ; graphene oxide ; iron oxides ; mass transfer ; oxidation ; singlet oxygen
Language	English
Dates of publication	2022-0215
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	1491302-1
ISSN	1873-3336 ; 0304-3894
ISSN (online)	1873-3336
ISSN	0304-3894
DOI	10.1016/j.jhazmat.2021.127342
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Article: Is HFPO-DA (GenX) a suitable substitute for PFOA? A comprehensive degradation comparison of PFOA and GenX via electrooxidation

Yang, Li-Hui / Yang, Wen-Jian / Lv, Si-Hao / Zhu, Ting-Ting / Adeel Sharif, Hafiz Muhammad / Yang, Cao / Du, Juan / Lin, Hui

Environmental research. 2022 Mar., v. 204

2022

Abstract: Due to the potential hazard of perfluorooctanoic acid (PFOA), hexafluoropropylene oxide dimer acid (HFPO-DA, GenX) has become a typical alternative since 2009. However, GenX has recently been reported to have equal or even greater toxicity and ... ...

Abstract	Due to the potential hazard of perfluorooctanoic acid (PFOA), hexafluoropropylene oxide dimer acid (HFPO-DA, GenX) has become a typical alternative since 2009. However, GenX has recently been reported to have equal or even greater toxicity and bioaccumulation than PFOA. Considering the suitability of alternatives, it is quite essential to study and compare the degradation degree between PFOA and GenX in water. Therefore, in the present study, a comprehensive degradation comparison between them via electrooxidation with a titanium suboxide membrane anode was conducted. The degradation rate decreased throughout for PFOA, while it first increased and then decreased for GenX when the permeate flux increased from 17.3 L to 100.3 L m⁻²·h⁻¹. The different responses of PFOA and GenX to flux might be attributed to their different solubilities. In addition, the higher kₒbₛ of PFOA demonstrated that it had a better degradability than GenX by 2.4-fold in a mixed solution. The fluorinated byproduct perfluoropropanoic acid (PFPrA) was detected as a GenX intermediate, suggesting that ether bridge splitting was needed for GenX electrooxidation. This study provides a reference for assessing the degradability of GenX and PFOA and indicates that it is worth reconsidering whether GenX is a suitable alternative for PFOA from the point of view of environmental protection.
Keywords	anodes ; bioaccumulation ; byproducts ; environmental protection ; perfluorooctanoic acid ; research ; titanium ; toxicity
Language	English
Dates of publication	2022-03
Publishing place	Elsevier Inc.
Document type	Article
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2021.111995
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Article: LncRNA ANRIL promotes multiple myeloma progression and bortezomib resistance by EZH2-mediated epigenetically silencing of PTEN.

Yang, Li-Hui / Du, Peng / Liu, Wei / An, Li-Kun / Li, Jian / Zhu, Wen-Yi / Yuan, Shuo / Wang, Lei / Zang, Lei

Neoplasma

2021 Volume 68, Issue 4, Page(s) 788–797

Abstract: Multiple myeloma (MM) is a plasma cell malignancy of bone marrow. In the present study, we aimed to study the function and potential mechanism of the antisense non-coding RNA in the INK4 Locus (ANRIL) in MM. The expression levels of ANRIL in MM patients ... ...

Abstract	Multiple myeloma (MM) is a plasma cell malignancy of bone marrow. In the present study, we aimed to study the function and potential mechanism of the antisense non-coding RNA in the INK4 Locus (ANRIL) in MM. The expression levels of ANRIL in MM patients and healthy donors were evaluated by quantitative real-time polymerase chain reaction (qRT-PCR). The effects and mechanisms of ANRIL in MM were evaluated by cell viability assay, BrdU incorporation assay, tumor xenograft model, flow cytometry, western blot, RNA immunoprecipitation (RIP), transcriptome RNA sequencing, and chromatin immunoprecipitation (ChIP). We found that ANRIL was upregulated in MM patients and cell lines, and associated with advanced international staging system (ISS) stage and poor overall survival. Enforced ANRIL expression promoted proliferation and tumor xenograft growth of MM cells, while knockdown of ANRIL exhibited opposite effects. Moreover, ANRIL overexpression increased the half-maximal inhibitory concentration (IC50) of bortezomib and reduced bortezomib-induced apoptosis in MM cells. ANRIL was found to accumulate in the nuclei of MM cells, and interact with EZH2 by RIP assay. Transcriptome RNA sequencing identified PTEN as a target of ANRIL in MM cells. In the ChIP assay, knockdown of ANRIL reduced EZH2 occupancy and H3K27me3 binding to the promoter region of PTEN. Furthermore, EZH2 knockout or PTEN restoration abrogated the effects caused by ANRIL overexpression in MM cells. Our results indicated that ANRIL exerted oncogenic functions and conferred chemoresistance of MM cells by EZH2-mediated epigenetically silencing of PTEN.
MeSH term(s)	Apoptosis ; Bortezomib/pharmacology ; Cell Proliferation ; Enhancer of Zeste Homolog 2 Protein/genetics ; Humans ; Multiple Myeloma/drug therapy ; Multiple Myeloma/genetics ; PTEN Phosphohydrolase/genetics ; RNA, Long Noncoding/genetics
Chemical Substances	RNA, Long Noncoding ; Bortezomib (69G8BD63PP) ; EZH2 protein, human (EC 2.1.1.43) ; Enhancer of Zeste Homolog 2 Protein (EC 2.1.1.43) ; PTEN Phosphohydrolase (EC 3.1.3.67) ; PTEN protein, human (EC 3.1.3.67)
Language	English
Publishing date	2021-05-26
Publishing country	Slovakia
Document type	Journal Article
ZDB-ID	415445-9
ISSN	0028-2685
ISSN	0028-2685
DOI	10.4149/neo_2021_210205N184
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Zs.A 28: Show issues

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Article ; Online: Recent advances in hybrid wet scrubbing techniques for NO

Sharif, Hafiz Muhammad Adeel / Mahmood, Nasir / Wang, Shengye / Hussain, Ijaz / Hou, Ya-Nan / Yang, Li-Hui / Zhao, Xu / Yang, Bo

Chemosphere

2021 Volume 273, Page(s) 129695

Abstract: Recently, the discharge of flue gas has become a global issue due to the rapid development in industrial and anthropogenic activities. Various dry and wet treatment approaches including conventional and hybrid hybrid wet scrubbing have been employing to ... ...

Abstract	Recently, the discharge of flue gas has become a global issue due to the rapid development in industrial and anthropogenic activities. Various dry and wet treatment approaches including conventional and hybrid hybrid wet scrubbing have been employing to combat against these toxic exhaust emissions. However, certain issues i.e., large energy consumption, generation of secondary pollutants, low regeneration of scrubbing liquid and high efficieny are hindering their practical applications on industrial level. Despite this, the hybrid wet scrubbing technique (advanced oxidation, ionic-liquids and solid engineered interface hybrid materials based techniques) is gaining great attention because of its low installation costs, simultaneous removal of multi-air pollutants and low energy requirements. However, the lack of understanding about the basic principles and fundamental requirements are great hurdles for its commercial scale application, which is aim of this review article. This review article highlights the recent developments, minimization of GHG, sustainable improvements for the regeneration of used catalyst via green and electron rich donors. It explains, various hybrid wet scrubbing techniques can perform well under mild condition with possible improvements such as development of stable, heterogeneous catalysts, fast and in-situ regeneration for large scale applications. Finally, it discussed recovery of resources i.e., N
MeSH term(s)	Air Pollutants/analysis ; Catalysis ; Oxidation-Reduction ; Sulfur Dioxide/analysis
Chemical Substances	Air Pollutants ; Sulfur Dioxide (0UZA3422Q4)
Language	English
Publishing date	2021-01-22
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	120089-6
ISSN	1879-1298 ; 0045-6535 ; 0366-7111
ISSN (online)	1879-1298
ISSN	0045-6535 ; 0366-7111
DOI	10.1016/j.chemosphere.2021.129695
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Zs.A 2540: Show issues

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Article ; Online: Is HFPO-DA (GenX) a suitable substitute for PFOA? A comprehensive degradation comparison of PFOA and GenX via electrooxidation.

Yang, Li-Hui / Yang, Wen-Jian / Lv, Si-Hao / Zhu, Ting-Ting / Adeel Sharif, Hafiz Muhammad / Yang, Cao / Du, Juan / Lin, Hui

Environmental research

2021 Volume 204, Issue Pt A, Page(s) 111995

Abstract	Due to the potential hazard of perfluorooctanoic acid (PFOA), hexafluoropropylene oxide dimer acid (HFPO-DA, GenX) has become a typical alternative since 2009. However, GenX has recently been reported to have equal or even greater toxicity and bioaccumulation than PFOA. Considering the suitability of alternatives, it is quite essential to study and compare the degradation degree between PFOA and GenX in water. Therefore, in the present study, a comprehensive degradation comparison between them via electrooxidation with a titanium suboxide membrane anode was conducted. The degradation rate decreased throughout for PFOA, while it first increased and then decreased for GenX when the permeate flux increased from 17.3 L to 100.3 L m
MeSH term(s)	Bioaccumulation ; Caprylates ; Fluorocarbons/analysis ; Water Pollutants, Chemical/analysis
Chemical Substances	Caprylates ; Fluorocarbons ; Water Pollutants, Chemical ; perfluorooctanoic acid (947VD76D3L)
Language	English
Publishing date	2021-09-04
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	205699-9
ISSN	1096-0953 ; 0013-9351
ISSN (online)	1096-0953
ISSN	0013-9351
DOI	10.1016/j.envres.2021.111995
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Article: [：Q].

Wei, Su-Jung / Chang, Hsiao-Yun / Chen, Shu-Ming / Yeh, Shu-Hui / Yang, Li-Hui

Hu li za zhi The journal of nursing

2019 Volume 66, Issue 6, Page(s) 33–42

Abstract: Background: The gap between the expectation and the development of role competency is a dilemma that nurse practitioners (NPs) face in clinical settings.: Purpose: This study was designed to explore the perceived importance and actual practice of the ...

Abstract	Background: The gap between the expectation and the development of role competency is a dilemma that nurse practitioners (NPs) face in clinical settings. Purpose: This study was designed to explore the perceived importance and actual practice of the role competencies of NPs and to compare the differences between the ideal and practical domains as well as related factors. Methods: This cross-sectional design study used Q-sort to collect data. A 56-item "Nurse Practitioner Role Capacity Questionnaire" was used as the research tool. Two questionnaires: Perceptions of Important Role Competencies and Actual Execution of Role Competencies were distributed to NPs twice, at times that were 2 weeks apart. A total of 40 participants were recruited, including 21(52.5%) internal medicine NPs and 19 (47.5%) surgical medicine NPs. Results: The significant differences that were identified in this study between the perceived importance and actual practice of role competencies were, by domain: medical assistance (t = -5.62, p < .001), clinical research (t = 4.14, p < .001), professional consultation (t = 2.29, p = .027), and direct care (t = 2.21, p = .033). The correlative factors for these differences were: education level (t = -2.17, p = .036) and membership in the Nurse Practitioner Association (t = -2.36, p = .017). NPs with higher levels of education and with membership in the Nurse Practitioner Association earned higher scores for self-expectation in important clinical competency. Conclusions: NPs face discrepancies in their role expectations, in important part due to their role as providers of medical assistance in clinical practical settings. NPs need to learn and demonstrate the roles and functions of advanced nursing practice to enhance nursing professionalism profoundly.
MeSH term(s)	Clinical Competence ; Cross-Sectional Studies ; Humans ; Nurse Practitioners/psychology ; Nurse's Role/psychology ; Q-Sort ; Surveys and Questionnaires
Language	Chinese
Publishing date	2019-12-04
Publishing country	China (Republic : 1949- )
Document type	Journal Article
ISSN	0047-262X
ISSN	0047-262X
DOI	10.6224/JN.201912_66(6).06
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Article ; Online: A retrospective analysis of 25 cases of Addison's disease caused by adrenal tuberculosis in Tibet and review of related literature.

Zeding, Zhuoma / Liu, Lin / Wang, Chen / Tian, Qing / Zhang, JunQing / Zen, Yan / Zhang, Ni / Shen, Jing / Na A, Mi / BaSang, PuChi / Lv, XueMei / Yang, SenLin / Meng, ShuYou / Yang, LiHui

Journal of clinical tuberculosis and other mycobacterial diseases

2023 Volume 31, Page(s) 100358

Abstract: Background: To investigate the clinical characteristics of Addison's disease caused by adrenal tuberculosis in Tibet. After the anti-tuberculosis treatment, the clinical features between continuous glucocorticoid therapy and glucocorticoid withdrawal ... ...

Abstract	Background: To investigate the clinical characteristics of Addison's disease caused by adrenal tuberculosis in Tibet. After the anti-tuberculosis treatment, the clinical features between continuous glucocorticoid therapy and glucocorticoid withdrawal were analyzed. Methods: Clinical data of patients with Addison's disease caused by adrenal tuberculosis diagnosed in The People's Hospital of Tibet Autonomous Region from January 2015 to October 2021 were collected and analyzed. All patients were taking anti-tuberculosis and glucocorticoids replacement therapy, and the root cause of the disease was analyzed following prognosis observations. Results: There were 25 patients (24 Tibetan and 1 Han patient) with Addison's disease caused by adrenal tuberculosis, including 18 males and 7 females. A total of 21 cases were followed up successfully, of which 13 cases discontinued anti-tuberculosis drugs successfully, 6 cases discontinued glucocorticoid therapy among the rest, 6 cases continued anti-tuberculosis + glucocorticoid replacement therapy, and 2 cases died. Conclusion: Early diagnosis and proper anti-tuberculosis treatment can improve the prognosis of patients with adrenal tuberculosis. Moreover, screening and educating Tibetan people regarding the potential risk and adversities of adrenal tuberculosis is crucial for eradicating the disease.
Language	English
Publishing date	2023-03-06
Publishing country	England
Document type	Journal Article
ISSN	2405-5794
ISSN (online)	2405-5794
DOI	10.1016/j.jctube.2023.100358
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Article ; Online: A tartrate-EDTA-Fe complex mediates electron transfer and enhances ammonia recovery in a bioelectrochemical-stripping system.

Zhang, De-Xin / Zhai, Si-Yuan / Zeng, Ran / Liu, Cheng-Yan / Zhang, Bo / Yu, Zhe / Yang, Li-Hui / Li, Xi-Qi / Hou, Ya-Nan / Wang, Ai-Jie / Cheng, Hao-Yi

Environmental science and ecotechnology

2022 Volume 11, Page(s) 100186

Abstract: Traditional bioelectrochemical systems (BESs) coupled with stripping units for ammonia recovery suffer from an insufficient supply of electron acceptors due to the low solubility of oxygen. In this study, we proposed a novel strategy to efficiently ... ...

Abstract	Traditional bioelectrochemical systems (BESs) coupled with stripping units for ammonia recovery suffer from an insufficient supply of electron acceptors due to the low solubility of oxygen. In this study, we proposed a novel strategy to efficiently transport the oxidizing equivalent provided at the stripping unit to the cathode by introducing a highly soluble electron mediator (EM) into the catholyte. To validate this strategy, we developed a new kind of iron complex system (tartrate-EDTA-Fe) as the EM. EDTA-Fe contributed to the redox property with a midpoint potential of -0.075 V (vs. standard hydrogen electrode, SHE) at pH 10, whereas tartrate acted as a stabilizer to avoid iron precipitation under alkaline conditions. At a ratio of the catholyte recirculation rate to the anolyte flow rate (R
Language	English
Publishing date	2022-05-20
Publishing country	Netherlands
Document type	Journal Article
ISSN	2666-4984
ISSN (online)	2666-4984
DOI	10.1016/j.ese.2022.100186
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Article: A tartrate-EDTA-Fe complex mediates electron transfer and enhances ammonia recovery in a bioelectrochemical-stripping system

Zhang, De-Xin / Zhai, Si-Yuan / Zeng, Ran / Liu, Cheng-Yan / Zhang, Bo / Yu, Zhe / Yang, Li-Hui / Li, Xi-Qi / Hou, Ya-Nan / Wang, Ai-Jie / Cheng, Hao-Yi

Environmental science & ecotechnology. 2022 May 13,

2022

Abstract	Traditional bioelectrochemical systems (BESs) coupled with stripping units for ammonia recovery suffer from an insufficient supply of electron acceptors due to the low solubility of oxygen. In this study, we proposed a novel strategy to efficiently transport the oxidizing equivalent provided at the stripping unit to the cathode by introducing a highly soluble electron mediator (EM) into the catholyte. To validate this strategy, we developed a new kind of iron complex system (tartrate-EDTA-Fe) as the EM. EDTA-Fe contributed to the redox property with a midpoint potential of −0.075 V (vs. standard hydrogen electrode, SHE) at pH 10, whereas tartrate acted as a stabilizer to avoid iron precipitation under alkaline conditions. At a ratio of the catholyte recirculation rate to the anolyte flow rate (RC₋A) of 12, the NH₄⁺-N recovery rate in the system with 50 mM tartrate-EDTA-Fe complex reached 6.9 ± 0.2 g N m⁻² d⁻¹, approximately 3.8 times higher than that in the non-EM control. With the help of the complex, our system showed an NH₄⁺-N recovery performance comparable to that previously reported but with an extremely low RC₋A (0.5 vs. 288). The strategy proposed here may guide the future of ammonia recovery BES scale-up because the introduction of an EM allows aeration to be performed only at the stripping unit instead of at every cathode, which is beneficial for the system design due to its simplicity and reliability.
Keywords	aeration ; ammonia ; cathodes ; electron transfer ; environmental science ; hydrogen ; oxygen ; pH ; solubility ; stabilizers ; systems engineering
Language	English
Dates of publication	2022-0513
Publishing place	Elsevier B.V.
Document type	Article
Note	Pre-press version
ISSN	2666-4984
DOI	10.1016/j.ese.2022.100186
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