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Article: Learning from success: A machine learning approach to guiding solar building envelope applications in non-domestic market

Weerasinghe, Nilmini Pradeepika / Yang, Rebecca Jing / Wang, Chen

Journal of cleaner production. 2022 Nov. 10, v. 374

2022

Abstract: Solar building envelopes, also known as Building Integrated PV (BIPV) show significant growth in Asia and Europe, although other regions such as Australia are still lagging. The decision to uptake BIPV is complex due to the heterogeneous interest of ... ...

Abstract	Solar building envelopes, also known as Building Integrated PV (BIPV) show significant growth in Asia and Europe, although other regions such as Australia are still lagging. The decision to uptake BIPV is complex due to the heterogeneous interest of adopters and multi-dimensional features. Instead of redesigning BIPV in hypothetical buildings, we built a machine learning model using a database of real BIPV and building-attached PV (BAPV) applications, for the purpose of learning and predicting a BIPV adoption decision-making in non-domestic buildings in western countries. We used Australia as a case study to execute the support vector machine (SVM) prediction model. It was revealed that the combination of project determinants such as geographical conditions, equivalent building materials, interest rates and capital cost influenced the decision of BIPV. The prediction model provides pieces of information for stakeholders across the BIPV ecosystem to take their decision on investment, policymaking, and research directions. The current global industry transformation and innovations in technology are favourable to politically promoting and investing in BIPV. Such promotion and investment would help both expand the current market and reach the greenhouse targets.
Keywords	capital costs ; case studies ; databases ; decision making ; ecosystems ; greenhouses ; industry ; markets ; models ; stakeholders ; support vector machines ; Asia ; Australia ; Europe
Language	English
Dates of publication	2022-1110
Publishing place	Elsevier Ltd
Document type	Article
ISSN	0959-6526
DOI	10.1016/j.jclepro.2022.133997
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Interleukin-2 Transiently Inhibits Pulsatile Growth Hormone Secretion in Young but not Older Healthy Men.

Roelfsema, Ferdinand / Yang, Rebecca / Veldhuis, Johannes D

The Journal of clinical endocrinology and metabolism

2021 Volume 106, Issue 10, Page(s) 2855–2864

Abstract: Context: Interleukin-2 (IL-2), a proinflammatory cytokine, has been used to treat malignancies. Increased cortisol and adrenocorticotropin (ACTH) were noted, but growth hormone (GH) secretion was not investigated in detail.: Objective: We quantified ... ...

Abstract	Context: Interleukin-2 (IL-2), a proinflammatory cytokine, has been used to treat malignancies. Increased cortisol and adrenocorticotropin (ACTH) were noted, but growth hormone (GH) secretion was not investigated in detail. Objective: We quantified GH secretion after a single subcutaneous injection of IL-2 in 17 young and 18 older healthy men in relation to dose, age, and body composition. Methods: This was a placebo-controlled, blinded, prospectively randomized, crossover study. At 20:00 hours IL-2 (3 or 6 million units/m2) or saline was injected subcutaneously. Lights were off between 23:00 and 07:00 hours. Blood was sampled at 10-minute intervals for 24 hours. Outcome measures included convolution analysis of GH secretion. Results: GH profiles were pulsatile under both experimental conditions and lower in older than young volunteers. Since the effect of IL-2 might be time limited, GH analyses were performed on the complete 24-hour series and the 6 hours after IL-2 administration. Total and pulsatile 24-hour GH secretion decreased nonsignificantly. Pulsatile secretion fell over the first 6 hours after IL-2 (P = .03), with visceral fat as a covariate (P = .003), but not age (P = .10). Plots of cumulative 2-hour bins of GH pulse mass showed a distinction by treatment and age groups: A temporary GH decrease of 32% and 28% occurred in the first 2-hour bins after midnight (P = .02 and .04) in young participants, whereas in older individuals no differences were present at any time point. Conclusion: This study demonstrates that IL-2 temporarily diminishes GH secretion in young, but not older, men.
MeSH term(s)	Adolescent ; Adult ; Age Factors ; Aged ; Aged, 80 and over ; Cross-Over Studies ; Double-Blind Method ; Growth Hormone/drug effects ; Healthy Volunteers ; Humans ; Injections, Subcutaneous ; Interleukin-2/pharmacology ; Male ; Middle Aged ; Prospective Studies ; Secretory Pathway/drug effects ; Time Factors ; Young Adult
Chemical Substances	Interleukin-2 ; Growth Hormone (9002-72-6)
Language	English
Publishing date	2021-06-22
Publishing country	United States
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, N.I.H., Extramural
ZDB-ID	3029-6
ISSN	1945-7197 ; 0021-972X
ISSN (online)	1945-7197
ISSN	0021-972X
DOI	10.1210/clinem/dgab484
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Article: A multi-objective optimization framework for building-integrated PV envelope design balancing energy and cost

Samarasinghalage, Tharushi I. / Wijeratne, W.M. Pabasara U. / Yang, Rebecca J. / Wakefield, Ron

Journal of cleaner production. 2022 Mar. 15, v. 342

2022

Abstract: The design of building-integrated photovoltaic (BIPV) envelopes involves a large set of envelope-related parameters, PV-related parameters and conflicting performance criteria. Therefore, optimization of BIPV design is crucial and it has become a complex ...

Abstract	The design of building-integrated photovoltaic (BIPV) envelopes involves a large set of envelope-related parameters, PV-related parameters and conflicting performance criteria. Therefore, optimization of BIPV design is crucial and it has become a complex process. Existing BIPV design optimization frameworks lack BIPV product and application type-related variables, and most studies cannot handle large sets of design variables and automatically generate a set of alternative optimal designs. Therefore, an optimization framework has become a major requirement in BIPV envelope design. This study introduces a multi-objective optimization (MOO) framework to optimize life cycle energy (LCE) and life cycle cost (LCC) simultaneously, at the conceptual BIPV envelope design stage, considering different BIPV application types for the selection of appropriate BIPV products and designs. A set of envelope design features, as well as PV-related features such as tilt angle, window-to-wall ratio (WWR), PV placement and PV product type, are included as design variables in the framework. The novelty of this study is that it generates a set of the best BIPV design alternatives based on multiple objectives, PV products and building features. Alternative designs include the best building surface features and the best BIPV product for a given performance criterion. The framework is demonstrated using canopy, roof sheet and cladding BIPV applications and the results incorporate different design solutions for each case study. The results show that MOO is operational for early BIPV design decisions based on technical considerations of energy and cost. Mid-design stage decisions can be guided by these simulated results but are not sufficient to define design decisions. Client subjectivity, taste and preference may heavily impact the feasibility of applying the optimization results, because in some cases, energy optimization is not the overarching goal of the client.
Keywords	canopy ; case studies ; cladding ; energy ; life cycle costing ; taste
Language	English
Dates of publication	2022-0315
Publishing place	Elsevier Ltd
Document type	Article
ISSN	0959-6526
DOI	10.1016/j.jclepro.2022.130930
Database	NAL-Catalogue (AGRICOLA)

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Article: Multi-objective optimisation for building integrated photovoltaics (BIPV) roof projects in early design phase

Wijeratne, W.M. Pabasara Upalakshi / Samarasinghalage, Tharushi Imalka / Yang, Rebecca Jing / Wakefield, Ron

Applied energy. 2022 Mar. 01, v. 309

2022

Abstract: Building-integrated photovoltaics (BIPV) is an excellent renewable energy application for building envelopes. In Australia, BIPV roofing is considered to be promising because of recent major concerns about fire risks of façades. However, the integration ... ...

Abstract	Building-integrated photovoltaics (BIPV) is an excellent renewable energy application for building envelopes. In Australia, BIPV roofing is considered to be promising because of recent major concerns about fire risks of façades. However, the integration of PV into building envelope elements is a complicated process which, if not done properly, may lead to failure of the BIPV system. Therefore, feasible BIPV design solutions need to be examined in terms of life-cycle cost and energy performance from the early design phase of a BIPV envelope project. There have been few investigations of the identification of feasible BIPV design options in the early design phase to enable product selection and parametric tests. This study explores a multi-objective optimization method which formulates feasible BIPV envelope design options which have relatively high energy generation and low life cycle costs to informed decision making. The optimisation process has four segments: data inputs, simulator, optimizer and pareto front based optimised BIPV solutions. The proposed multi- objective optimization process is applied in a BIPV roof application using a case study in Australia with roof sheets and skylights. The results demonstrate seven optimum roof sheet BIPV design solutions and fourteen optimum skylight BIPV design solutions to enable design makers to compare and select the most appropriate. The life cycle cost, life cycle energy, CO₂ emissions avoided, net present value, payback period, and levelized cost of energy of BIPV solutions vary based on the BIPV modules, tilt angles and placement locations. The proposed optimization method is a helpful guide for BIPV design professionals to identify suitable BIPV design options in the early design phase instead of relying on rule-of-thumb experience.
Keywords	carbon dioxide ; case studies ; energy ; life cycle costing ; solar energy ; system optimization ; Australia
Language	English
Dates of publication	2022-0301
Publishing place	Elsevier Ltd
Document type	Article
ZDB-ID	2000772-3
ISSN	0306-2619
ISSN	0306-2619
DOI	10.1016/j.apenergy.2021.118476
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Optional Web-Based Videoconferencing Added to Office-Based Care for Women Receiving Psychotherapy During the Postpartum Period: Pilot Randomized Controlled Trial.

Yang, Rebecca / Vigod, Simone N / Hensel, Jennifer M

Journal of medical Internet research

2019 Volume 21, Issue 6, Page(s) e13172

Abstract: Background: Depression and anxiety during the postpartum period are common, with psychotherapy often being the preferred method of treatment. However, psychological, physical, and social barriers prevent women from receiving appropriate and timely ... ...

Abstract	Background: Depression and anxiety during the postpartum period are common, with psychotherapy often being the preferred method of treatment. However, psychological, physical, and social barriers prevent women from receiving appropriate and timely psychotherapy. The option of receiving psychotherapy through videoconferencing (VC) during the postpartum period presents an opportunity for more accessible and flexible care. Objective: The aim of this study was to assess the feasibility, acceptability, and preliminary effectiveness of optional VC added to usual office-based psychotherapy, with a psychotherapist during the postpartum period. Methods: We conducted a pilot randomized controlled trial with 1:1 randomization to office-based care (treatment as usual; TAU) or office-based care with the option of VC (treatment as usual plus videoconferencing; TAU-VC) for psychotherapy during the postpartum period. We assessed the ability to recruit and retain postpartum women into the study from an urban perinatal mental health program offering postpartum psychotherapy, and we evaluated the uptake, acceptability, and satisfaction with VC as an addition to in-person psychotherapy. We also compared therapy attendance using therapist logs and symptoms between treatment groups. Symptoms were assessed at baseline and 3 months postrandomization with the Edinburgh Postnatal Depression Scale, Generalized Anxiety Disorder 7-item, and Parental Stress Scale. Furthermore, 3-month scores were compared between groups with intention-to-treat linear mixed-effects models controlling for baseline score. Results: We enrolled 38 participants into the study, with 19 participants in each treatment group. Attendance data were available for all participants, with follow-up symptom measures available for 25 out of 38 participants (66%). Among the 19 TAU-VC participants, 14 participants (74%) utilized VC at least once. Most participants were highly satisfied with the VC option, and they reported average savings of Can $26 and 2.5 hours in travel and childcare expenses and time per appointment. There were no significant differences between the 2 groups for psychotherapy attendance or symptoms. Conclusions: The option of VC appears to be an acceptable method of receiving psychotherapy for postpartum women, with benefits described in costs and time savings. On the basis of this small pilot sample, there were no significant differences in outcomes between office-based care with or without the option of VC. This study has demonstrated the feasibility of such a program in an urban center, which suggests that a larger study would be beneficial to provide evidence that is more conclusive.
MeSH term(s)	Adult ; Female ; Humans ; Internet ; Mental Health/standards ; Pilot Projects ; Postpartum Period/psychology ; Pregnancy ; Psychotherapy/methods ; Surveys and Questionnaires ; Videoconferencing/standards
Language	English
Publishing date	2019-05-20
Publishing country	Canada
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	2028830-X
ISSN	1438-8871 ; 1438-8871
ISSN (online)	1438-8871
ISSN	1438-8871
DOI	10.2196/13172
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: An investigation of stakeholder analysis in urban development projects

Yang, Rebecca Jing

International journal of project management : the journal of The International Project Management Association Vol. 32, No. 5 , p. 838-849

empirical or rationalistic perspective

2014 Volume 32, Issue 5, Page(s) 838–849

Author's details	Rebecca Jing Yang
Keywords	Stakeholder analysis ; Urban development projects ; Empiricism ; Rationalism
Language	English
Size	graph. Darst.
Publisher	Elsevier
Publishing place	Amsterdam [u.a.]
Document type	Article
ZDB-ID	797899-6
ISSN	0263-7863
Database	ECONomics Information System

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Article ; Online: Differential Effects of Estradiol and Progesterone on Cardiovascular Risk Factors in Postmenopausal Women.

Roelfsema, Ferdinand / Yang, Rebecca J / Veldhuis, Johannes D

Journal of the Endocrine Society

2018 Volume 2, Issue 7, Page(s) 794–805

Abstract: Context: Controlled, blinded studies of sex-hormone replacement in postmenopausal women using natural estradiol (E: Objective: To delineate the effect of E: Design: A placebo-controlled, double-masked, prospectively randomized study of 40 healthy, ...

Abstract	Context: Controlled, blinded studies of sex-hormone replacement in postmenopausal women using natural estradiol (E Objective: To delineate the effect of E Design: A placebo-controlled, double-masked, prospectively randomized study of 40 healthy, postmenopausal volunteers assigned to four treatment groups: placebo, intramuscular E Results: Treatment with E Conclusion: In this study, there were individual and interactive effects of E
Language	English
Publishing date	2018-06-14
Publishing country	United States
Document type	Journal Article
ISSN	2472-1972
ISSN (online)	2472-1972
DOI	10.1210/js.2018-00073
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Article ; Online: Estradiol Does Not Influence Lipid Measures and Inflammatory Markers in Testosterone-Clamped Healthy Men.

Roelfsema, Ferdinand / Yang, Rebecca J / Veldhuis, Johannes D

Journal of the Endocrine Society

2018 Volume 2, Issue 8, Page(s) 882–892

Abstract: Context: Experimentally controlled studies of estrogenic regulation of lipid measures and inflammatory cytokines in men are rare.: Objective: To delineate the effect of estradiol (E: Design: This was a placebo-controlled, single-masked, ... ...

Abstract	Context: Experimentally controlled studies of estrogenic regulation of lipid measures and inflammatory cytokines in men are rare. Objective: To delineate the effect of estradiol (E Design: This was a placebo-controlled, single-masked, prospectively randomized study comprising experimentally degarelix-downregulated healthy men [n = 74; age 65 years (range, 57 to 77)] assigned to four treatment groups: (1) IM saline and oral placebo; (2) IM testosterone and oral placebo; (3) IM testosterone and oral anastrozole (aromatase inhibitor); and (4) IM testosterone, oral anastrozole, and transdermal E Results: Mean mass spectrometry-quantified serum E Conclusion: In this placebo-controlled prospectively randomized study, wide variations in circulating E
Language	English
Publishing date	2018-06-29
Publishing country	United States
Document type	Journal Article
ISSN	2472-1972
ISSN (online)	2472-1972
DOI	10.1210/js.2018-00141
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Modulating Effects of Progesterone on Spontaneous Nocturnal and Ghrelin-Induced GH Secretion in Postmenopausal Women.

Roelfsema, Ferdinand / Yang, Rebecca J / Bowers, Cyril Y / Veldhuis, Johannes D

The Journal of clinical endocrinology and metabolism

2019 Volume 104, Issue 6, Page(s) 2385–2394

Abstract: Background: Oral administration of estradiol (E2) generally increases GH secretion in postmenopausal women. Oral administration of E2 is associated with a decrease in IGF-1, whereas parenteral or transdermally administered E2 may have no effect on GH. ... ...

Abstract	Background: Oral administration of estradiol (E2) generally increases GH secretion in postmenopausal women. Oral administration of E2 is associated with a decrease in IGF-1, whereas parenteral or transdermally administered E2 may have no effect on GH. The effect of progesterone (P4) on GH secretion has rarely been studied. We hypothesized that moderately increased serum E2 levels stimulate GH and that P4 modulates E2-stimulated GH secretion. Study design: Four parallel groups of randomly assigned postmenopausal women (n = 40). Treatments were saline placebo and oral placebo, saline placebo and oral micronized P4 (3 × 200 mg/d IM), E2 (5 mg IM) and oral placebo, and E2 IM and oral micronized P4. Outcome measures were overnight GH secretion (10 hours), stimulated (ghrelin, 0.3 µg/kg IV bolus) GH secretion, and CT-estimated visceral fat. Results: Intramuscular E2 administration did not alter nocturnal and ghrelin-stimulated GH secretion. Nocturnal GH secretion was not changed by P4 administration. However, P4 diminished ghrelin-stimulated pulsatile GH release with or without E2 (average, 7.20 ± 2.14 and 9.58 ± 1.97 µg/L/2 h, respectively; P = 0.045). Respective outcomes for mean GH concentrations and GH peak amplitudes were 0.97 ± 0.31 and 1.52 μg/L ± 0.29 (P = 0.025) and 2.76 ± 1.04 and 3.95 μg/L ± 0.90 (P = 0.031). Ghrelin-stimulated GH secretion correlated negatively with P4 concentration with or without correction for visceral fat area in the regression equation (R = 0.49, P = 0.04, β = -0.040 ± 0.016). Conclusions: Low-range physiological E2 concentrations do not affect spontaneous or ghrelin-stimulated pulsatile GH secretion. Conversely, P4 inhibits ghrelin-stimulated GH secretion in a concentration-dependent fashion. The mechanistic aspects and physiological significance of natural P4's regulation of ghrelin-evoked GH secretion require further study.
MeSH term(s)	Aged ; Aged, 80 and over ; Double-Blind Method ; Estradiol/pharmacology ; Female ; Ghrelin/pharmacology ; Human Growth Hormone/blood ; Human Growth Hormone/metabolism ; Humans ; Middle Aged ; Postmenopause ; Progesterone/pharmacology ; Prospective Studies
Chemical Substances	Ghrelin ; Human Growth Hormone (12629-01-5) ; Progesterone (4G7DS2Q64Y) ; Estradiol (4TI98Z838E)
Language	English
Publishing date	2019-02-02
Publishing country	United States
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	3029-6
ISSN	1945-7197 ; 0021-972X
ISSN (online)	1945-7197
ISSN	0021-972X
DOI	10.1210/jc.2018-02639
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Uh III Zs.134: Show issues

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Article: Interleukin-2 drives cortisol secretion in an age-, dose-, and body composition-dependent way.

Roelfsema, Ferdinand / Liu, Peter Y / Yang, Rebecca / Takahashi, Paul / Veldhuis, Johannes D

Endocrine connections

2020 Volume 9, Issue 7, Page(s) 637–648

Abstract: Background: Interleukin-2 (IL-2), one of the proinflammatory cytokines, is used in the treatment of certain malignancies. In some studies, transient increases in cortisol and ACTH secretion occurred. Thus, this agent may be used as an experimental probe ...

Abstract	Background: Interleukin-2 (IL-2), one of the proinflammatory cytokines, is used in the treatment of certain malignancies. In some studies, transient increases in cortisol and ACTH secretion occurred. Thus, this agent may be used as an experimental probe of adrenal cortisol secretion. Objective: This study quantifies the effects of low and moderate doses of IL-2 on cortisol secretion and assesses the modulation by age, dose and body composition. Site: Mayo Clinical Translational Research Unit. Subjects: Study comprised 35 healthy men, 17 young and 18 older. Methods: Randomized prospective double-blind saline-controlled study of IL-2 administration in two doses with concurrent 10-min blood sampling for 24 h. Outcome measures: Deconvolution analysis and approximate entropy of cortisol secretion. Results: Low-dose IL-2 administration increased nocturnal pulsatile cortisol secretion from 1460 ± 160 to 2120 ± 220 nmol/L/8 h in young subjects and from 1680 ± 105 to 1960 ± 125 nmol/L/8 h (treatment P < 0.0001, but more in young than older, P = 0.02). Comparable results were obtained for total cortisol secretion (P treatment <0.0001, age effect P = 0.005). The higher IL-2 dose caused a large increase in young (P < 0.0001), but not in older (P = 0.90) subjects. This dose also increased approximate entropy from 0.877 ± 0.041 to 1.024 ± 0.049 (P = 0.008), pointing to reduced secretory orderliness. Incremental cortisol (nocturnal) secretion correlated negatively with visceral fat mass (R = -0.41, P = 0.019). Conclusion: In healthy men, IL-2 injection drives pulsatile cortisol secretion in a dose-dependent way in young, but not older, individuals and erodes cortisol secretory orderliness at a higher dose in young subjects. Cortisol responses are diminished with increasing abdominal visceral fat mass.
Language	English
Publishing date	2020-06-12
Publishing country	England
Document type	Journal Article
ZDB-ID	2668428-7
ISSN	2049-3614
ISSN	2049-3614
DOI	10.1530/EC-20-0211
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