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Article: Storytelling and user experience in the cultural metaverse.

Yang, Shuran

2023 Volume 9, Issue 4, Page(s) e14759

Abstract: Enthusiasm for the metaverse is intensifying in academia and industries. The metaverse is a complex concept, combining many technologies to create many different types of user experiences (UX), depending on the intended use. The cultural metaverse was ... ...

Abstract	Enthusiasm for the metaverse is intensifying in academia and industries. The metaverse is a complex concept, combining many technologies to create many different types of user experiences (UX), depending on the intended use. The cultural metaverse was first introduced in this study. This study is an initial attempt to fill the gaps in the practical research and storytelling research in the metaverse. Augmented reality (AR) technology is an applicative tool in cultural experience, which displays computer - generated virtual information on a real-world scene. AR displays digital information realistically, making it appear to be part of the actual environment, deepening or expanding the user's understanding of "reality". This study constructed a cultural metaverse using the innovative AR storytelling. The cultural metaverse is a new cultural ecology in which advanced information technologies are deeply integrated with cultural spaces and exhibits. It combines digital technologies and cultural industries, mixing virtual space and physical space to facilitate the UX in cultural experiences. In this study, the existing AR e-book and the innovative AR version were compared while measuring multiple aspects of UX, including presence, flow, enjoyment, education, and engagement. By analyzing questionnaire data from two groups with a total of 368 participants, the results indicated that the innovative AR storytelling produced a better UX across all variables compared to the AR e-book application. Overall, innovative AR storytelling allows visitors to transition between real and virtual spaces, enriches their interactive experience, and improves user engagement with the metaverse exhibition of cultural experience. Therefore, practitioners can construct a primary cultural metaverse through innovative AR storytelling.
Language	English
Publishing date	2023-03-22
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e14759
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Storytelling and user experience in the cultural metaverse

Yang, Shuran

Heliyon. 2023 Apr., v. 9, no. 4 p.e14759-

2023

Abstract	Enthusiasm for the metaverse is intensifying in academia and industries. The metaverse is a complex concept, combining many technologies to create many different types of user experiences (UX), depending on the intended use. The cultural metaverse was first introduced in this study. This study is an initial attempt to fill the gaps in the practical research and storytelling research in the metaverse. Augmented reality (AR) technology is an applicative tool in cultural experience, which displays computer - generated virtual information on a real-world scene. AR displays digital information realistically, making it appear to be part of the actual environment, deepening or expanding the user's understanding of "reality". This study constructed a cultural metaverse using the innovative AR storytelling. The cultural metaverse is a new cultural ecology in which advanced information technologies are deeply integrated with cultural spaces and exhibits. It combines digital technologies and cultural industries, mixing virtual space and physical space to facilitate the UX in cultural experiences. In this study, the existing AR e-book and the innovative AR version were compared while measuring multiple aspects of UX, including presence, flow, enjoyment, education, and engagement. By analyzing questionnaire data from two groups with a total of 368 participants, the results indicated that the innovative AR storytelling produced a better UX across all variables compared to the AR e-book application. Overall, innovative AR storytelling allows visitors to transition between real and virtual spaces, enriches their interactive experience, and improves user engagement with the metaverse exhibition of cultural experience. Therefore, practitioners can construct a primary cultural metaverse through innovative AR storytelling.
Keywords	augmented reality ; computers ; ecology ; education ; questionnaires ; Engagement ; Storytelling ; Metaverse ; Experience economy theory ; User experience ; AR ; AVE ; CR ; IVE ; UX ; VR ; VIF
Language	English
Dates of publication	2023-04
Publishing place	Elsevier Ltd
Document type	Article ; Online
Note	Use and reproduction
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e14759
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Presence and Flow in the Context of Virtual Reality Storytelling: What Influences Enjoyment in Virtual Environments?

Yang, Shuran / Zhang, Wenxiang

Cyberpsychology, behavior and social networking

2021 Volume 25, Issue 2, Page(s) 101–109

Abstract: Virtual reality (VR) has widely been implemented in a variety of industries, with immersive storytelling now gaining popularity in the field of journalism. In this regard, there are many important questions about which direction modern journalism should ... ...

Abstract	Virtual reality (VR) has widely been implemented in a variety of industries, with immersive storytelling now gaining popularity in the field of journalism. In this regard, there are many important questions about which direction modern journalism should take as a whole. To test the feasibility of immersive storytelling, this study developed a cognitive experience model containing paths for presence, flow, credibility, empathy, understanding, and enjoyment. A total of 131 participants were divided into three groups and exposed to either VR, 360-degree videos, or two-dimensional (2D) videos, then asked to rate their experiences. With the exception of understanding, results showed that the VR and 360-degree videos were more highly evaluated in each path when compared with 2D videos. In this case, technical attributes did not greatly affect the study variables. However, presence played a vital role in news promotion, while flow was positively affected by presence; flow also affected other variables when combined with presence. Finally, a structural equation model was tested and the weights of the different influences on the enjoyment impact were presented. In sum, this study found that immersive storytelling improved both presence, flow, and credibility, which jointly and positively affected enjoyment. Understanding negatively affected enjoyment. Empathy had little effect on enjoyment in the model.
MeSH term(s)	Communication ; Emotions ; Empathy ; Humans ; Pleasure ; Virtual Reality
Language	English
Publishing date	2021-12-27
Publishing country	United States
Document type	Journal Article
ZDB-ID	2545735-4
ISSN	2152-2723 ; 2152-2715
ISSN (online)	2152-2723
ISSN	2152-2715
DOI	10.1089/cyber.2021.0037
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Article: Multiple pulmonary cavities in an immunocompetent patient: a case report and literature review.

Guo, Zihan / Zuo, Anli / Liu, Xinyi / Jiang, Yunxiu / Yang, Shuran / Lu, Degan

Frontiers in medicine

2024 Volume 11, Page(s) 1329381

Abstract: Legionella pneumonia (LP) is a relatively uncommon yet well-known type of atypical community-acquired pneumonia (CAP). It is characterized by a rapid progression to severe pneumonia and can be easily misdiagnosed. In most patients, chest computed ... ...

Abstract	Legionella pneumonia (LP) is a relatively uncommon yet well-known type of atypical community-acquired pneumonia (CAP). It is characterized by a rapid progression to severe pneumonia and can be easily misdiagnosed. In most patients, chest computed tomography (CT) showed patchy infiltration, which may progress to lobar infiltration or even lobar consolidation. While pulmonary cavities are commonly observed in immunocompromised patients with LP, they are considered rare in immunocompetent individuals. Herein, we present a case of LP in an immunocompetent patient with multiple cavities in both lungs. Pathogen detection was performed using metagenomic next-generation sequencing (mNGS). This case highlights the unusual radiographic presentation of LP in an immunocompetent patient and emphasizes the importance of considering LP as a possible diagnosis in patients with pulmonary cavities, regardless of their immune status. Furthermore, the timely utilization of mNGS is crucial for early pathogen identification, as it provides multiple benefits in enhancing the diagnosis and prognosis of LP patients.
Language	English
Publishing date	2024-02-27
Publishing country	Switzerland
Document type	Case Reports
ZDB-ID	2775999-4
ISSN	2296-858X
ISSN	2296-858X
DOI	10.3389/fmed.2024.1329381
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Article ; Online: Correlation Analysis of Microbial Contamination and Alkaline Phosphatase Activity in Raw Milk and Dairy Products.

Peng, Zixin / Li, Ying / Yan, Lin / Yang, Shuran / Yang, Dajin

International journal of environmental research and public health

2023 Volume 20, Issue 3

Abstract: Microbial contamination in raw milk and dairy products can detrimentally affect product quality and human health. In this study, the aerobic plate count, ... ...

Abstract	Microbial contamination in raw milk and dairy products can detrimentally affect product quality and human health. In this study, the aerobic plate count, aerobic
MeSH term(s)	Animals ; Alkaline Phosphatase/metabolism ; Bacillus/isolation & purification ; Bacillus/metabolism ; Bacteria/isolation & purification ; Bacteria/metabolism ; Colony Count, Microbial ; Food Microbiology ; Milk/metabolism ; Milk/microbiology ; Public Health
Chemical Substances	Alkaline Phosphatase (EC 3.1.3.1)
Language	English
Publishing date	2023-01-19
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph20031825
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Article ; Online: Antimicrobial-Resistant Evolution and Global Spread of

Peng, Zixin / Yan, Lin / Yang, Shuran / Yang, Dajin

China CDC weekly

2022 Volume 4, Issue 2, Page(s) 17–21

Abstract: For a long time, ...

Abstract	For a long time,
Language	English
Publishing date	2022-05-13
Publishing country	China
Document type	Journal Article ; Review
ISSN	2096-7071
ISSN (online)	2096-7071
DOI	10.46234/ccdcw2021.277
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Article ; Online: The occurrence, ecological risk, and control of disinfection by-products from intensified wastewater disinfection during the COVID-19 pandemic

Xue, Bin / Guo, Xuan / Cao, Jinrui / Yang, Shuran / Qiu, Zhigang / Wang, Jingfeng / Shen, Zhiqiang

Science of the Total Environment. 2023, p.165602-

2023 , Page(s) 165602–

Abstract: Increased disinfection of wastewater to preserve its microbiological quality during the coronavirus infectious disease-2019 (COVID-19) pandemic have inevitably led to increased production of toxic disinfection by-products (DBPs). However, there is ... ...

Abstract	Increased disinfection of wastewater to preserve its microbiological quality during the coronavirus infectious disease-2019 (COVID-19) pandemic have inevitably led to increased production of toxic disinfection by-products (DBPs). However, there is limited information on such DBPs (i.e., trihalomethanes, haloacetic acids, nitrosamines, and haloacetonitriles). This review focused on the upsurge of chlorine-based disinfectants (such as chlorine, chloramine and chlorine dioxide) in wastewater treatment plants (WWTPs) in the global response to COVID-19. The formation and distribution of DBPs in wastewater were then analyzed to understand the impacts of these large-scale usage of disinfectants in WWTPs. In addition, potential ecological risks associated with DBPs derived from wastewater disinfection and its receiving water bodies were summarized. Finally, various approaches for mitigating DBP levels in wastewater and suggestions for further research into the environmental risks of increased wastewater disinfection were provided. Overall, this study presented a comprehensive overview of the formation, distribution, potential ecological risks, and mitigating approaches of DBPs derived from wastewater disinfection that will facilitate appropriate wastewater disinfection techniques selection, potential ecological risk assessment, and removal approaches and regulations consideration.
Keywords	COVID-19 infection ; chlorine ; chlorine dioxide ; disinfection ; environment ; environmental assessment ; microbiological quality ; nitrosamines ; pandemic ; risk ; toxicity ; wastewater ; wastewater treatment ; Wastewater disinfection ; Disinfection by-products ; Ecological risk ; The coronavirus infectious disease-2019
Language	English
Publishing place	Elsevier B.V.
Document type	Article ; Online
Note	Pre-press version
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2023.165602
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Article ; Online: Effect of core and veneer porcelain thickness and resin cement on opalescence property of glass-ceramic veneers.

Li, Zhemin / Ma, Wenjie / Yang, Shuran / Yang, Qiusong / Wang, Jianing / Yao, Zhangshun / Lin, Yunhong / Li, Xingxing

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology

2024 Volume 40, Issue 4, Page(s) 403–408

Abstract: Objectives: This study aimed to analyze the effect of core and veneer porcelain thickness and resin cement on the opalescence property (OP) of glass-ceramic veneers, which were used to restore discolored teeth.: Methods: IPS e.max CAD LT A3 ceramic ... ...

Abstract	Objectives: This study aimed to analyze the effect of core and veneer porcelain thickness and resin cement on the opalescence property (OP) of glass-ceramic veneers, which were used to restore discolored teeth. Methods: IPS e.max CAD LT A3 ceramic specimens were fabricated by computer aided design and computer aided manufacturing (CAD/CAM). The thickness values of core porcelain groups were 0.25 and 0.50 mm, and those of the core/veneer porcelain groups were 0.25 mm core/0.25 mm dentin, 0.50 mm core/0.25 mm dentin, 0.50 mm core/0.50 mm dentin, and 0.50 mm core/0.25 mm dentin/0.25 mm incisal. To simulate the clinical bonding procedure of porcelain veneer, resin cement Variolink N Bleach XL was coated at the bottom of CAD/CAM porcelain veneer specimens to make composite specimens of CAD/CAM porcelain veneer and resin cement. The Results: The OP values of 0.25 and 0.50 mm core porcelain groups, and 0.25 mm core/0.25 mm dentin, 0.50 mm core/0.25 mm dentin, 0.50 mm core/0.50 mm dentin, and 0.50 mm core/0.25 mm dentin/0.25 mm incisal core/veneer porcelain groups were 6.10±0.50, 7.00±0.24, 6.40±0.24, 7.08±0.28, 7.16±0.21, and 7.86±0.11 respectively. With increasing thickness of core porcelain, the OP values increased significantly ( Conclusions: When using glass-ceramic veneers for discolored teeth, the following are recommended to improve the OP and obtain a natural and realistic effect: adopt the design of direct sintering incisal porcelain with core porcelain; appropriately increase the thickness of core porcelain; and select resin cement with opaque effect.
Language	Chinese
Publishing date	2024-04-10
Publishing country	China
Document type	Journal Article
ZDB-ID	1202342-5
ISSN	2618-0456 ; 1000-1182
ISSN (online)	2618-0456
ISSN	1000-1182
DOI	10.7518/hxkq.2022.04.005
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Article ; Online: The efficacy and safety of continuous intravenous infusion of rh-endostatin combined with platinum-based doublet chemotherapy for advanced non-small-cell lung cancer.

Liu, Xinyi / Guo, Zihan / Su, Lin / Zuo, Anli / Gao, Min / Ji, Xiang / Lu, Jiameng / Yang, Shuran / Jiang, Yunxiu / Lu, Degan

Investigational new drugs

2024

Abstract: Background: Platinum-based doublet chemotherapy is commonly used in the treatment of non-small cell lung cancer (NSCLC). A growing body of evidence indicates that incorporating antiangiogenic agents into platinum-based chemotherapy may enhance the ... ...

Abstract	Background: Platinum-based doublet chemotherapy is commonly used in the treatment of non-small cell lung cancer (NSCLC). A growing body of evidence indicates that incorporating antiangiogenic agents into platinum-based chemotherapy may enhance the survival outcomes for NSCLC patients. However, the optimal administration protocol for intravenous recombinant human endostatin (rh-endostatin), an antiangiogenic agent, remains uncertain at present. Aim: This study aims to investigate the efficacy and safety of 5-d continuous intravenous infusion of rh-endostatin in combination with chemotherapy for patients with advanced NSCLC. The predictive biomarkers for this treatment regimen were further probed. Methods: This prospective, single-arm multicenter study enrolled a total of 48 patients with advanced NSCLC who were histologically or cytologically confirmed but had not received any prior treatment from January 2021 to December 2022. Prior to the chemotherapy, these patients received a continuous intravenous infusion of rh-endostatin (210 mg) over a period of 120 h, using an infusion pump. The chemotherapy regimen included a combination of platinum with either pemetrexed or paclitaxel, given in 21-day cycles. The primary endpoint of the study was median progression-free survival (mPFS), and the secondary endpoints included median overall survival (mOS), objective response rate (ORR), disease control rate (DCR), and assessment of adverse events (AEs). Results: The mPFS was 6.5 months (95% confidence interval (CI): 3.8-9.1 m) while the mOS was 12.3 months (95% CI: 7.6-18.5 m). The ORR and DCR was 52.1% and 75.0%, respectively. Leukopenia (52.1%), anemia (33.3%), and thrombocytopenia (20.8%) were the most common adverse effects and these toxicities were deemed acceptable and manageable. In addition, a correlation was noted between elevated serum carcinoembryonic antigen (CEA) levels and decreased PFS and OS. Conclusions: The incorporation of a 5-day continuous intravenous infusion of rh-endostatin into platinum-based doublet chemotherapy has demonstrated both safety and efficacy in the treatment of advanced NSCLC. Furthermore, the baseline serum levels of CEA may potentially function as a predictor for the efficacy of rh-endostatin when combined with chemotherapy in NSCLC patients. Clinicaltrials: GOV: NCT05574998.
Language	English
Publishing date	2024-05-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	604895-x
ISSN	1573-0646 ; 0167-6997
ISSN (online)	1573-0646
ISSN	0167-6997
DOI	10.1007/s10637-024-01439-x
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Article ; Online: Chlorite and bromate alter the conjugative transfer of antibiotic resistance genes: Co-regulation of oxidative stress and energy supply.

Cao, Jinrui / Xue, Bin / Yang, Shuran / Yang, Xiaobo / Zhang, Xi / Qiu, Zhigang / Shen, Zhiqiang / Wang, Jingfeng

Journal of hazardous materials

2024 Volume 471, Page(s) 134257

Abstract: The widespread use of disinfectants during the global response to the 2019 coronavirus pandemic has increased the co-occurrence of disinfection byproducts (DBPs) and antibiotic resistance genes (ARGs). Although DBPs pose major threats to public health ... ...

Abstract	The widespread use of disinfectants during the global response to the 2019 coronavirus pandemic has increased the co-occurrence of disinfection byproducts (DBPs) and antibiotic resistance genes (ARGs). Although DBPs pose major threats to public health globally, there is limited knowledge regarding their biological effects on ARGs. This study aimed to investigate the effects of two inorganic DBPs (chlorite and bromate) on the conjugative transfer of RP4 plasmid among Escherichia coli strains at environmentally relevant concentrations. Interestingly, the frequency of conjugative transfer was initially inhibited when the exposure time to chlorite or bromate was less than 24 h. However, this inhibition transformed into promotion when the exposure time was extended to 36 h. Short exposures to chlorite or bromate were shown to impede the electron transport chain, resulting in an ATP shortage and subsequently inhibiting conjugative transfer. Consequently, this stimulates the overproduction of reactive oxygen species (ROS) and activation of the SOS response. Upon prolonged exposure, the resurgent energy supply promoted conjugative transfer. These findings offer novel and valuable insights into the effects of environmentally relevant concentrations of inorganic DBPs on the conjugative transfer of ARGs, thereby providing a theoretical basis for the management of DBPs.
MeSH term(s)	Escherichia coli/genetics ; Escherichia coli/drug effects ; Oxidative Stress/drug effects ; Bromates/toxicity ; Plasmids/genetics ; Chlorides/pharmacology ; Disinfectants/pharmacology ; Reactive Oxygen Species/metabolism ; Conjugation, Genetic/drug effects ; Drug Resistance, Microbial/genetics ; Drug Resistance, Bacterial/genetics ; Drug Resistance, Bacterial/drug effects ; SOS Response, Genetics/drug effects
Chemical Substances	Bromates ; chlorite (Z63H374SB6) ; Chlorides ; Disinfectants ; Reactive Oxygen Species
Language	English
Publishing date	2024-04-09
Publishing country	Netherlands
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1491302-1
ISSN	1873-3336 ; 0304-3894
ISSN (online)	1873-3336
ISSN	0304-3894
DOI	10.1016/j.jhazmat.2024.134257
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