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  1. Article ; Online: Komagataella pastoris: A new yeast probiotic for depression?

    Yang, Tao

    Pharmacological research

    2021  Volume 171, Page(s) 105762

    MeSH term(s) Animals ; Antidepressive Agents/therapeutic use ; Depression/drug therapy ; Humans ; Probiotics/therapeutic use ; Saccharomycetales
    Chemical Substances Antidepressive Agents
    Language English
    Publishing date 2021-07-07
    Publishing country Netherlands
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ZDB-ID 1003347-6
    ISSN 1096-1186 ; 0031-6989 ; 1043-6618
    ISSN (online) 1096-1186
    ISSN 0031-6989 ; 1043-6618
    DOI 10.1016/j.phrs.2021.105762
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 721: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Deciphering the photocatalytic hydrogen generation process of Fresnoite Ba

    Lu, Guangxiang / Yang, Tao

    Dalton transactions (Cambridge, England : 2003)

    2023  Volume 52, Issue 12, Page(s) 3769–3776

    Abstract: In addition to enhancing the activity of already-known photocatalysts, developing new ones is always desired in photocatalysis, giving more opportunities to approach practical applications. Most photocatalysts are composed of ... ...

    Abstract In addition to enhancing the activity of already-known photocatalysts, developing new ones is always desired in photocatalysis, giving more opportunities to approach practical applications. Most photocatalysts are composed of d
    Language English
    Publishing date 2023-03-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/d2dt03969a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Sexual Dimorphic Interplays Between Gut Microbiota and Antihypertensive Drugs.

    Bardhan, Pritam / Yang, Tao

    Current hypertension reports

    2023  Volume 25, Issue 8, Page(s) 163–172

    Abstract: Purpose of the review: The purpose of this study is to review the current literature regarding gut microbiota in blood pressure regulation and its interactions with antihypertensive drugs and to discuss how sex differences in gut microbiota contribute ... ...

    Abstract Purpose of the review: The purpose of this study is to review the current literature regarding gut microbiota in blood pressure regulation and its interactions with antihypertensive drugs and to discuss how sex differences in gut microbiota contribute to sexual dimorphism of hypertension and treatment.
    Recent findings: The significance of gut microbiota in blood pressure regulation and hypertension etiology is growingly recognized. Targeting the dysbiotic microbiota is proposed to be a new therapeutic method. Recently, a few studies demonstrated that the gut microbiota is highly involved in the modulation of the efficacy of antihypertensive drugs, suggesting a novel mechanism by which gut microbiota plays a role in treatment-resistant hypertension. Furthermore, studies on sex differences in gut microbiota, etiology of hypertension, and sex bias in prescription of antihypertensive medications have revealed promising avenues in sexual dimorphism-based precision medicine. However, no scientific questions are ever raised on how sex differences in gut microbiota contribute to the sex specific responses of certain classes of antihypertensive drugs. Given the dynamics and complexity among individuals, precision medicine is proposed of great potential. We review current knowledge on the interactions between gut microbiota, hypertension, and antihypertensive drugs with an emphasis on sex as a crucial determinant. We propose that sex differences in gut microbiota be a research focus to advance our understanding of hypertension management.
    MeSH term(s) Humans ; Male ; Female ; Antihypertensive Agents/therapeutic use ; Hypertension/drug therapy ; Gastrointestinal Microbiome/physiology ; Blood Pressure ; Microbiota
    Chemical Substances Antihypertensive Agents
    Language English
    Publishing date 2023-05-18
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2057367-4
    ISSN 1534-3111 ; 1522-6417
    ISSN (online) 1534-3111
    ISSN 1522-6417
    DOI 10.1007/s11906-023-01244-6
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    Zs.A 5522: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Causal Associations of Education Level With Cardiovascular Diseases, Cardiovascular Biomarkers, and Socioeconomic Factors.

    Hu, Mengjin / Yang, Tao / Yang, Yuejin

    The American journal of cardiology

    2024  Volume 213, Page(s) 76–85

    Abstract: An inverse association of education level with cardiovascular diseases has been documented in observational studies, yet the causality and potential mechanisms remain to be determined. To systematically investigate the causal associations of education ... ...

    Abstract An inverse association of education level with cardiovascular diseases has been documented in observational studies, yet the causality and potential mechanisms remain to be determined. To systematically investigate the causal associations of education level with cardiovascular diseases, cardiovascular biomarkers, and socioeconomic factors, a 2-sample Mendelian randomization was performed. The results revealed that higher genetically determined education level was associated with lower risks of type 2 diabetes mellitus (odds ratio [OR] 0.54, 95% confidence interval [CI] 0.47 to 0.61, p = 3.04 × 10
    MeSH term(s) Humans ; Cardiovascular Diseases/epidemiology ; Diabetes Mellitus, Type 2/epidemiology ; Educational Status ; Socioeconomic Factors ; Biomarkers ; Mendelian Randomization Analysis/methods ; Genome-Wide Association Study ; Polymorphism, Single Nucleotide
    Chemical Substances Biomarkers
    Language English
    Publishing date 2024-01-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2023.06.044
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    Ui IV Zs.73: Show issues Location:
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  5. Article: [Genetic and phenotypic analysis of

    Lin, Yun / Xu, Jun / Yang, Tao

    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery

    2024  Volume 38, Issue 1, Page(s) 38–43

    Abstract: Objective: ...

    Abstract Objective:
    MeSH term(s) Humans ; Pedigree ; China ; Deafness/genetics ; Hearing Loss/genetics ; Phenotype ; Hearing Loss, Sensorineural/genetics ; Mutation ; Myosins/genetics
    Chemical Substances MYO15A protein, human ; Myosins (EC 3.6.4.1)
    Language Chinese
    Publishing date 2024-02-01
    Publishing country China
    Document type English Abstract ; Journal Article
    ISSN 2096-7993
    ISSN 2096-7993
    DOI 10.13201/j.issn.2096-7993.2024.01.006
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  6. Article ; Online: The role of Down syndrome cell adhesion molecule in Down syndrome.

    Hergenreder, Ty / Yang, Tao / Ye, Bing

    Medical review (2021)

    2024  Volume 4, Issue 1, Page(s) 31–41

    Abstract: Down syndrome (DS) is caused by the presence of an extra copy of the entire or a portion of human chromosome 21 (HSA21). This genomic alteration leads to elevated expression of numerous HSA21 genes, resulting in a variety of health issues in individuals ... ...

    Abstract Down syndrome (DS) is caused by the presence of an extra copy of the entire or a portion of human chromosome 21 (HSA21). This genomic alteration leads to elevated expression of numerous HSA21 genes, resulting in a variety of health issues in individuals with DS. Among the genes located in the DS "critical region" of HSA21, Down syndrome cell adhesion molecule (DSCAM) plays an important role in neuronal development. There is a growing body of evidence underscoring DSCAM's involvement in various DS-related disorders. This review aims to provide a concise overview of the established functions of DSCAM, with a particular focus on its implications in DS. We delve into the roles that DSCAM plays in DS-associated diseases. In the concluding section of this review, we explore prospective avenues for future research to further unravel DSCAM's role in DS and opportunities for therapeutic treatments.
    Language English
    Publishing date 2024-02-09
    Publishing country Germany
    Document type Journal Article ; Review
    ISSN 2749-9642
    ISSN (online) 2749-9642
    DOI 10.1515/mr-2023-0056
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: HSP 90β (HSP90AB1) as a potential biomarker and therapeutic target for Ménière's disease.

    Mao, Qiuyue / Yang, Tao / Peng, Anquan / Wang, Qin

    Asian journal of surgery

    2024  

    Language English
    Publishing date 2024-02-20
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2024.01.115
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    Zs.B 2831: Show issues Location:
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  8. Article ; Online: Key technical factors for elite 50 m rifle 3 positions shooting performance.

    Lang, Diandong / Wang, Fei / Wang, Nianhui / Yang, Tao

    Sports biomechanics

    2024  , Page(s) 1–11

    Abstract: The purpose of this study was to analyse the differences on the shooting score and shooting technical parameters with 50 m rifle three positions, and to find the key technical factors of shooting performance in international-level 50 m rifle shooters. A ... ...

    Abstract The purpose of this study was to analyse the differences on the shooting score and shooting technical parameters with 50 m rifle three positions, and to find the key technical factors of shooting performance in international-level 50 m rifle shooters. A SCATT MX-02 optoelectronic shooting test system was used to collect shooting score and shooting technical variables. There was a significant effect of shooting position in shooting performance, aiming accuracy, stability of hold, stability of triggering (ANOVA, position,
    Language English
    Publishing date 2024-02-25
    Publishing country England
    Document type Journal Article
    ISSN 1752-6116
    ISSN (online) 1752-6116
    DOI 10.1080/14763141.2024.2319130
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  9. Article ; Online: Contralateral knee osteoarthritis is a risk factor for ipsilateral knee osteoarthritis progressing: a case control study.

    Dai, Zhengxu / Yang, Tao / Liu, Jun

    BMC musculoskeletal disorders

    2024  Volume 25, Issue 1, Page(s) 190

    Abstract: Background: Knee osteoarthritis (KOA) is a highly disabling disease, and studying its progression is crucial. However, it is still unclear whether the progression of ipsilateral knee osteoarthritis is influenced by contralateral knee osteoarthritis.: ... ...

    Abstract Background: Knee osteoarthritis (KOA) is a highly disabling disease, and studying its progression is crucial. However, it is still unclear whether the progression of ipsilateral knee osteoarthritis is influenced by contralateral knee osteoarthritis.
    Methods: Data were collected from the OAI database and divided into two study cohorts (right/left KOA cohort). Each cohort had a target knee (right/left knee) and was further divided into two groups (exposure/control group). The demographic data of both cohorts were balanced at baseline by propensity score matching (PSM), and the data included rating scale and radiographic and clinical data. After checking for balance in the matched variables, we then compared the differences between the two groups in each cohort. Our primary focus was on the minimum joint space width (mJSW) of the target knee, which was measured four years after baseline. The secondary outcome was the arthroplasty rate of the target knee within nine years.
    Results: In this study, a total of 678 participants were enrolled and matched. After 1:1 PSM of the baseline demographic data, 98 participants in the right KOA cohort (RKOAC) were successfully matched, and 117 participants in the left KOA cohort (LKOAC) were successfully matched. Furthermore, the standardized mean difference (SMD) of the matched variables in both cohorts was less than 0.25. After analyzing the outcome metrics, we found that the target knee had a significantly lower mJSW in the fourth year after baseline and a significantly greater arthroplasty rate within nine years in the exposed group than in the control group. RKOAC: mJSW (exposure: 2.6(1.1 ~ 3.6) vs. control: 3.3(2.0 ~ 4.2), P < 0.05), arthroplasty rate (exposure: 14(14.3%) vs. control: 4(4.1%), P < 0.05); LKOAC: mJSW (exposure: 3.1(2 ~ 3.9) vs. control: 3.4(2.6 ~ 4.2), P < 0.05), arthroplasty rate (exposure: 16(13.7%) vs. control: 7(6%), P < 0.05).
    Conclusions: Patients with knee osteoarthritis experienced greater progression of osteoarthritis when the contralateral knee was also affected.
    MeSH term(s) Humans ; Osteoarthritis, Knee/diagnostic imaging ; Osteoarthritis, Knee/epidemiology ; Osteoarthritis, Knee/surgery ; Case-Control Studies ; Knee Joint/diagnostic imaging ; Knee Joint/surgery ; Arthroplasty, Replacement, Knee ; Risk Factors
    Language English
    Publishing date 2024-03-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2041355-5
    ISSN 1471-2474 ; 1471-2474
    ISSN (online) 1471-2474
    ISSN 1471-2474
    DOI 10.1186/s12891-024-07292-6
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  10. Article ; Online: Nickel-Catalyzed Reductive Alkene Cross-Dialkylation with Unactivated Alkyl Electrophiles.

    Yang, Huixia / Zhang, Zeming / Cao, Panting / Yang, Tao

    Organic letters

    2024  Volume 26, Issue 6, Page(s) 1190–1195

    Abstract: A Ni-catalyzed reductive dialkylation of 8-aminoquinoline-tethered aliphatic alkenes with two unactivated alkyl electrophiles is disclosed here. Key to the development of this transformation is the combination of primary alkyl (pseudo)halides and ... ...

    Abstract A Ni-catalyzed reductive dialkylation of 8-aminoquinoline-tethered aliphatic alkenes with two unactivated alkyl electrophiles is disclosed here. Key to the development of this transformation is the combination of primary alkyl (pseudo)halides and secondary alkyl iodides that produce products in a single regioselective manner. The reaction exhibits good functional group compatibility, and its synthetic utility was demonstrated by the concise synthesis of the precursors of biologically relevant molecules.
    Language English
    Publishing date 2024-02-03
    Publishing country United States
    Document type Journal Article
    ISSN 1523-7052
    ISSN (online) 1523-7052
    DOI 10.1021/acs.orglett.3c04207
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