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Article ; Online: Preparation and analysis of polysaccharide from Solanum tuberdsm.

Yang, Wenjian / Huang, Gangliang

2023 Volume 98, Page(s) 106520

Abstract: The crude Solanum tuberdsm polysaccharides (STP) were extracted with hot water. In the process of extraction, proteins, pigments, small molecules and salts in the mixture were removed by Sevage reagent, diatomite and distilled water dialysis, ... ...

Abstract	The crude Solanum tuberdsm polysaccharides (STP) were extracted with hot water. In the process of extraction, proteins, pigments, small molecules and salts in the mixture were removed by Sevage reagent, diatomite and distilled water dialysis, respectively. In addition, the process conditions of protein removal by response surface methodology (RSM) were optimized, and the optimum process conditions of Sevage method were established as follows: ultrasound power 350 W, ultrasound time 20 min, deproteinization twice, volume ratio of polysaccharide solution to Sevage reagent 1:1 (mL/mL). Under these conditions, the protein removal rate was 93.14%.
MeSH term(s)	Solanum ; Polysaccharides ; Water ; Proteins ; Antioxidants
Chemical Substances	Polysaccharides ; Water (059QF0KO0R) ; Proteins ; Antioxidants
Language	English
Publishing date	2023-07-08
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1208333-1
ISSN	1873-2828 ; 1350-4177
ISSN (online)	1873-2828
ISSN	1350-4177
DOI	10.1016/j.ultsonch.2023.106520
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Article ; Online: Psychological Stress Analysis to Evaluate the Effects of Transcranial Magnetic Stimulation on Mood Regulation and Quality of Life in Patients with Bipolar Disorder.

Qiang, Yueke / Yang, Wenjian / Yang, Bing

Actas espanolas de psiquiatria

2024 Volume 52, Issue 2, Page(s) 130–137

Abstract: Objective: To explore the impact of transcranial magnetic stimulation on emotion regulation and quality of life in patients with bipolar disorder (BD) and to evaluate the effectiveness of the mental stress analyzer.: Methods: Patients with BD ... ...

Abstract	Objective: To explore the impact of transcranial magnetic stimulation on emotion regulation and quality of life in patients with bipolar disorder (BD) and to evaluate the effectiveness of the mental stress analyzer. Methods: Patients with BD admitted to our hospital from August 2022 to August 2023 were retrospectively selected. For the present study, 60 patients who received drug therapy served as the control group, and the other 60 patients who received repeated transcranial stimulation on this basis served as the observation group. The heart rate variability (HRV) of the two groups of patients was detected by a mental stress analyzer/HRV analysis system. Hamilton Depression Rating Scale (HAMD), Self-Rating Anxiety Scale (SAS), and Self-Rating Depression Scale (SDS) were used to evaluate the mental state of the two groups of patients. The quality of life of the two groups was assessed using the Comprehensive Quality of Life Questionnaire 74 (GQOLI-74). Clinical effectiveness global rating scale-illness severity (CGI-SI) was used to evaluate the clinical symptoms of the two groups of patients, and the incidence of adverse reactions was calculated. Results: In comparison to the control group, the high-frequency power (HF) of the patients demonstrated an elevation in the observation group, and the low-frequency power (LF) and LF/HF were significantly reduced (p < 0.05). The standard deviation of NN intervals (SDNN), standard deviation of all five-minute NN intervals (SDANN), root mean square of successive differences (rMSSD), and percent RR intervals with a difference in duration higher than 50 ms (PNN50) of patients in the observation group showed a notable increase compared to the control group (p < 0.05). Compared with the control group, the HAMD, SAS, and SDS scores of the patients in the observation group demonstrated a substantial decline relative to the control group (p < 0.05). In contrast to the control group, there was a significant increase in the overall clinical effectiveness rate among patients in the observation group, and the incidence of adverse reactions was significantly reduced (p < 0.05). Conclusions: Repetitive transcranial magnetic stimulation (rTMS) has significant clinical effects in treating BD and can effectively improve patients' anxiety, suppress emotions, and regulate patients' emotions. At the same time, rTMS has high safety and little impact on the balance of patients' autonomic nervous function, reduces the incidence of adverse reactions, accelerates the patient's recovery process, and is suitable for clinical promotion.
MeSH term(s)	Humans ; Bipolar Disorder/therapy ; Retrospective Studies ; Quality of Life ; Transcranial Magnetic Stimulation ; Treatment Outcome
Language	English
Publishing date	2024-04-14
Publishing country	Spain
Document type	Journal Article
ZDB-ID	1480971-0
ISSN	1578-2735 ; 1575-071X ; 1139-9287
ISSN (online)	1578-2735
ISSN	1575-071X ; 1139-9287
DOI	10.62641/aep.v52i2.1555
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Article ; Online: Ultrasonic-assisted extraction, characteristics and activity of Ipomoea batatas polysaccharide.

Xiong, Xiong / Yang, Wenjian / Huang, Gangliang / Huang, Hualiang

Ultrasonics sonochemistry

2023 Volume 96, Page(s) 106420

Abstract: Ipomoea batatas polysaccharides (IBPs) have many important physiological functions. The optimal extraction conditions were extraction time of 40 min, solid-liquid ratio of 1:8 and ultrasonic power of 240 W. 1D/2D nuclear magnetic resonance (1D/2D NMR) ... ...

Abstract	Ipomoea batatas polysaccharides (IBPs) have many important physiological functions. The optimal extraction conditions were extraction time of 40 min, solid-liquid ratio of 1:8 and ultrasonic power of 240 W. 1D/2D nuclear magnetic resonance (1D/2D NMR) analysis showed that the main chain of IBP-1A was mainly composed of →4)-α-D-Glcp-(1→ and →3, 6)-β-D-Glcp-(1→ residues. In vivo experiments showed that polysaccharide significantly increased the levels of antioxidation-related enzymes and metabolites in older mice. It could significantly relieve oxidative stress injury and delay aging. Therefore, this study provided a new theoretical basis for the development of IBPs as antioxidant food.
MeSH term(s)	Animals ; Mice ; Ultrasonics ; Ipomoea batatas ; Polysaccharides/chemistry ; Antioxidants/chemistry ; Magnetic Resonance Spectroscopy
Chemical Substances	Polysaccharides ; Antioxidants
Language	English
Publishing date	2023-04-28
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	1208333-1
ISSN	1873-2828 ; 1350-4177
ISSN (online)	1873-2828
ISSN	1350-4177
DOI	10.1016/j.ultsonch.2023.106420
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Article ; Online: Extraction, structural characterization, and physicochemical properties of polysaccharide from purple sweet potato.

Yang, Wenjian / Huang, Gangliang

Chemical biology & drug design

2021 Volume 98, Issue 6, Page(s) 979–985

Abstract: The polysaccharide from purple sweet potato (PPSP) was extracted. The structure was characterized and partial physicochemical properties were described of PPSP via UV, IR, NMR, XRD, DSC-TGA, LDS, and Congo red assay. This study provided a theoretical ... ...

Abstract	The polysaccharide from purple sweet potato (PPSP) was extracted. The structure was characterized and partial physicochemical properties were described of PPSP via UV, IR, NMR, XRD, DSC-TGA, LDS, and Congo red assay. This study provided a theoretical basis for the in-depth structural analysis of PPSP and the study of its biological activity.
MeSH term(s)	Coloring Agents/chemistry ; Congo Red/chemistry ; Ipomoea batatas/chemistry ; Magnetic Resonance Spectroscopy ; Particle Size ; Polysaccharides/chemistry ; Polysaccharides/isolation & purification ; Spectrophotometry, Ultraviolet ; Sugars/analysis ; Thermogravimetry ; Uronic Acids/analysis ; X-Ray Diffraction
Chemical Substances	Coloring Agents ; Polysaccharides ; Sugars ; Uronic Acids ; Congo Red (3U05FHG59S)
Language	English
Publishing date	2021-09-26
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2216600-2
ISSN	1747-0285 ; 1747-0277
ISSN (online)	1747-0285
ISSN	1747-0277
DOI	10.1111/cbdd.13952
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Article ; Online: Effects of Flammulina velutipes polysaccharides on gut microbiota composition and metabolism in vitro fermentation

Su, Anxiang / Ma, Gaoxing / Ma, Ning / Pei, Fei / Yang, Wenjian / Hu, Qiuhui

Food Sci Biotechnol. 2023 Mar., v. 32, no. 3 p.361-369

2023

Abstract: Flammulina velutipes polysaccharides (FVP) exhibit many biological activities, but the effects on gut microflora and metabolism were still unclear. Here, we explored the composition of FVP, their influence on human gut microflora composition and ... ...

Abstract	Flammulina velutipes polysaccharides (FVP) exhibit many biological activities, but the effects on gut microflora and metabolism were still unclear. Here, we explored the composition of FVP, their influence on human gut microflora composition and metabolites. FVP were used to vitro fermentation through human fecal inoculums. In addition, 16S rRNA sequencing were used to assess the effects of FVP on the gut microbiota. The metabolic profiles were investigated using untargeted metabolomics approaches in the LC-MS platform. The results showed that FVP was mainly consisted of glucose, mannose, xylose, fucose and galactose. FVP is shown to increase the relative abundances of Bifidobacteriaceae, as well as Bacteroidaceae and remarkably decrease the numbers of genera Lachnospiraceae coupled with Enterococcaceae. The differential metabolites were identified and mainly involved the metabolism of glycerophospholipid, linoleic acid and synthesis of unsaturated fatty acids. FVP may exhibit biological activity function by regulating gut microflora composition and metabolites.
Keywords	Bacteroidaceae ; Bifidobacteriaceae ; Enterococcaceae ; Flammulina velutipes ; Lachnospiraceae ; bioactive properties ; fermentation ; fucose ; galactose ; glucose ; glycerophospholipids ; humans ; inoculum ; intestinal microorganisms ; linoleic acid ; mannose ; metabolites ; metabolomics ; polysaccharides ; xylose
Language	English
Dates of publication	2023-03
Size	p. 361-369.
Publishing place	Springer Nature Singapore
Document type	Article ; Online
ZDB-ID	2000008-X
ISSN	1226-7708
ISSN	1226-7708
DOI	10.1007/s10068-022-01192-y
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Article ; Online: Accurate Dimension Prediction for Low-Dimensional Organic-Inorganic Halide Perovskites via a Self-Established Machine Learning Strategy.

Yuan, Songyang / Liu, Yulin / Lan, Jing / Yang, Wenjian / Xiong, Hui / Li, Wenzhe / Fan, Jiandong

The journal of physical chemistry letters

2023 Volume 14, Issue 32, Page(s) 7323–7330

Abstract: Low-dimensional perovskites (LDPs) have enormous potential for the development of advanced optoelectronic devices and tackling the stability issue for the commercial application of perovskites. However, quantified structural dimensionality prediction for ...

Abstract	Low-dimensional perovskites (LDPs) have enormous potential for the development of advanced optoelectronic devices and tackling the stability issue for the commercial application of perovskites. However, quantified structural dimensionality prediction for LDPs is still an intractable issue. Herein, we develop a self-established machine learning (ML)-assisted approach to predict the dimensionality of LDPs based on 195 reported amines that are classified as two-dimensional, one-dimensional, and zero-dimensional. The optimal K-nearest neighbor model allows us to realize an accuracy rate of 92.3% for the test data set containing 39 reported amines. Two features, i.e., ATSC1pe and SlogP_VSA2, associated with polarity and electrostatic potential on the van der Waals surface of an organic spacer, are identified from >1800 descriptors as key controlling factors determining the structure dimensionality. This work develops a typical paradigm for the application of a multiple-classification strategy of ML with an extremely high accuracy rate, which would thereby motivate the development of new types of LDPs.
Language	English
Publishing date	2023-08-10
Publishing country	United States
Document type	Journal Article
ISSN	1948-7185
ISSN (online)	1948-7185
DOI	10.1021/acs.jpclett.3c01915
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Article ; Online: Production of Food-Derived Bioactive Peptides with Potential Application in the Management of Diabetes and Obesity: A Review.

Wang, Weiwei / Yang, Wenjian / Dai, Yi / Liu, Jianhui / Chen, Zhen-Yu

Journal of agricultural and food chemistry

2023

Abstract: The prevalence of diabetes mellitus and obesity is increasing worldwide. Bioactive peptides are naturally present in foods or in food-derived proteins. Recent research has shown that these bioactive peptides have an array of possible health benefits in ... ...

Abstract	The prevalence of diabetes mellitus and obesity is increasing worldwide. Bioactive peptides are naturally present in foods or in food-derived proteins. Recent research has shown that these bioactive peptides have an array of possible health benefits in the management of diabetes and obesity. First, this review will summarize the top-down and bottom-up production methods of the bioactive peptides from different protein sources. Second, the digestibility, bioavailability, and metabolic fate of the bioactive peptides are discussed. Last, the present review will discuss and explore the mechanisms by which these bioactive peptides help against obesity and diabetes based on
Language	English
Publishing date	2023-04-07
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	241619-0
ISSN	1520-5118 ; 0021-8561
ISSN (online)	1520-5118
ISSN	0021-8561
DOI	10.1021/acs.jafc.2c08835
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Article: Review on the Application of Hyperspectral Imaging Technology of the Exposed Cortex in Cerebral Surgery.

Wu, Yue / Xu, Zhongyuan / Yang, Wenjian / Ning, Zhiqiang / Dong, Hao

Frontiers in bioengineering and biotechnology

2022 Volume 10, Page(s) 906728

Abstract: The study of brain science is vital to human health. The application of hyperspectral imaging in biomedical fields has grown dramatically in recent years due to their unique optical imaging method and multidimensional information acquisition. ... ...

Abstract	The study of brain science is vital to human health. The application of hyperspectral imaging in biomedical fields has grown dramatically in recent years due to their unique optical imaging method and multidimensional information acquisition. Hyperspectral imaging technology can acquire two-dimensional spatial information and one-dimensional spectral information of biological samples simultaneously, covering the ultraviolet, visible and infrared spectral ranges with high spectral resolution, which can provide diagnostic information about the physiological, morphological and biochemical components of tissues and organs. This technology also presents finer spectral features for brain imaging studies, and further provides more auxiliary information for cerebral disease research. This paper reviews the recent advance of hyperspectral imaging in cerebral diagnosis. Firstly, the experimental setup, image acquisition and pre-processing, and analysis methods of hyperspectral technology were introduced. Secondly, the latest research progress and applications of hyperspectral imaging in brain tissue metabolism, hemodynamics, and brain cancer diagnosis in recent years were summarized briefly. Finally, the limitations of the application of hyperspectral imaging in cerebral disease diagnosis field were analyzed, and the future development direction was proposed.
Language	English
Publishing date	2022-05-27
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2719493-0
ISSN	2296-4185
ISSN	2296-4185
DOI	10.3389/fbioe.2022.906728
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Article ; Online: Emerging lead-free all inorganic perovskite single crystals K

Yang, Wenjian / Zhang, Jingshen / Xiong, Hui / Lan, Jing / Yuan, Songyang / Zhan, Mengdi / Tan, Ziyu / Li, Wenzhe / Fan, Jiandong

Dalton transactions (Cambridge, England : 2003)

2024 Volume 53, Issue 15, Page(s) 6609–6617

Abstract: Lead-free inorganic perovskites have attracted intensive attention in the field of photodetectors owing to their high stability, non-toxicity, and remarkable photoelectric characteristics. Herein, we designed and developed a series of thus-far unreported ...

Abstract	Lead-free inorganic perovskites have attracted intensive attention in the field of photodetectors owing to their high stability, non-toxicity, and remarkable photoelectric characteristics. Herein, we designed and developed a series of thus-far unreported lead-free all inorganic perovskite single crystals, K
Language	English
Publishing date	2024-04-16
Publishing country	England
Document type	Journal Article
ZDB-ID	1472887-4
ISSN	1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
ISSN (online)	1477-9234 ; 1364-5447
ISSN	0300-9246 ; 1477-9226
DOI	10.1039/d3dt03872f
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Article: Effect of cooked rice with added fructo-oligosaccharide on faecal microorganisms investigated by in vitro digestion and fermentation

Pei, Fei / Li, Wen / Ni, Xiaolei / Sun, Xinyang / Yao, Yijun / Fang, Yong / Yang, Wenjian / Hu, Qiuhui

Food science and human wellness. 2023 Mar., v. 12, no. 2

2023

Abstract: In the present study, the effects of cooked rice (CR) with added fructo-oligosaccharide (FOS) on faecal flora were studied by a simulated in vitro digestion and fermentation method. The total carbohydrate content, pH, and short-chain fatty acids (SCFAs) ... ...

Abstract	In the present study, the effects of cooked rice (CR) with added fructo-oligosaccharide (FOS) on faecal flora were studied by a simulated in vitro digestion and fermentation method. The total carbohydrate content, pH, and short-chain fatty acids (SCFAs) were determined during in vitro digestion and fermentation. The change in the bacterial phase distribution after the fermentation was also analysed. The results showed that the total carbohydrate content of the CR with added FOS (FCR) significantly decreased during the simulated digestion. Meanwhile, the pH of the FCR decreased and the SCFAs concentration increased significantly compared to those of the CR during the simulated fermentation. In addition, the FCR showed the advantage of promoting beneficial bacteria, such as Bifidobacterium and Lactobacillus, and inhibiting harmful bacteria, such as Bacteroides and Klebsiella compared to the CR. Therefore, the FOS as a prebiotic could be recommended to produce the high-quality healthy rice food.
Keywords	Bacteroides ; Bifidobacterium ; Klebsiella ; Lactobacillus ; carbohydrate content ; digestion ; fermentation ; food science ; fructooligosaccharides ; humans ; in vitro digestion ; intestinal microorganisms ; pH ; prebiotics ; rice
Language	English
Dates of publication	2023-03
Size	p. 662-668.
Publishing place	Elsevier B.V.
Document type	Article
ZDB-ID	2712869-6
ISSN	2213-4530
ISSN	2213-4530
DOI	10.1016/j.fshw.2022.07.068
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