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  1. Article ; Online: Study on the mechanisms by which pumpkin polysaccharides regulate abnormal glucose and lipid metabolism in diabetic mice under oxidative stress.

    Yang, Zeen / Chen, Shengdong / Sun, Wenxuan / Yang, Yechen / Xu, Yuxuan / Tang, Yuxuan / Jiang, Wen / Li, Jia / Zhang, Yongjun

    International journal of biological macromolecules

    2024  Volume 270, Issue Pt 2, Page(s) 132249

    Abstract: Pumpkin polysaccharide (PPe-H) can perform physiological functions through its antioxidative and hypoglycemic effects; however, the mechanisms through which PPe-H regulates abnormal glucose and lipid metabolism caused by oxidative stress injury remain ... ...

    Abstract Pumpkin polysaccharide (PPe-H) can perform physiological functions through its antioxidative and hypoglycemic effects; however, the mechanisms through which PPe-H regulates abnormal glucose and lipid metabolism caused by oxidative stress injury remain unclear. In the present study, streptozotocin was used to generate an acute diabetic mouse model, and the effects of PPe-H on glucose and lipid metabolism impaired by oxidative stress in diabetic mice were studied. PPe-H significantly reduced blood glucose levels and enhanced the oral glucose tolerance of diabetic mice under stress injury (p < 0.05). The analysis of liver antioxidant enzymes showed that PPe-H significantly enhanced the activities of SOD and CAT (p < 0.05), increased the GSH level, and decreased the level of MDA (p < 0.05). Transcriptomic and metabolomic analyses of the liver tissues of mice revealed characteristic differences in the genetic and metabolic levels of the samples, which showed that PPe-H treatment may play a positive role in regulating the metabolism of methionine, cysteine, glycerol phospholipid, and linoleic acid. These results indicated that PPe-H alleviated the symptoms of hyperglycemia by regulating metabolites related to oxidative stress and glycolipid metabolism in diabetic mice.
    Language English
    Publishing date 2024-05-09
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 282732-3
    ISSN 1879-0003 ; 0141-8130
    ISSN (online) 1879-0003
    ISSN 0141-8130
    DOI 10.1016/j.ijbiomac.2024.132249
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Stringent Emission Controls Are Needed to Reach Clean Air Targets for Cities in China under a Warming Climate

    Wang, Rong / Yang, Yechen / Xing, Xiaofan / Wang, Lin / Chen, Jianmin / Tang, Xu / Cao, Junji / Morawska, Lidia / Balkanski, Yves / Hauglustaine, Didier / Ciais, Philippe / Ma, Jianmin

    Environmental science & technology. 2022 July 26, v. 56, no. 16

    2022  

    Abstract: Quantifying the threat that climate change poses to fine particle (PM₂.₅) pollution is hampered by large uncertainties in the relationship between PM₂.₅ and meteorology. To constrain the impact of climate change on PM₂.₅, statistical models are often ... ...

    Abstract Quantifying the threat that climate change poses to fine particle (PM₂.₅) pollution is hampered by large uncertainties in the relationship between PM₂.₅ and meteorology. To constrain the impact of climate change on PM₂.₅, statistical models are often employed in a different manner than physical–chemical models to reduce the requirement of input data. A majority of statistical models predict PM₂.₅ concentration (often log-transformed) as a simple function of meteorology, which could be biased due to the conversion of precursor gases to PM₂.₅. We reduced this bias by developing a unique statistic model where the sum of PM₂.₅ and the weighted precursor gases, rather than the PM₂.₅ alone, was predicted as a function of meteorology and a proxy of primary emissions, where the input data of PM₁₀, CO, O₃, NOₓ, and SO₂ were obtained from routine measurements. This modification, without losing the simplicity of statistical models, reduced the mean-square error from 27 to 17% and increased the coefficient of determination from 47 to 67% in the model cross-validation using daily PM₂.₅ observations during 2013–2018 for 74 cities over China. We found a previously unrecognized mechanism that synoptic climate change in the past half-century might have increased low quantiles of PM₂.₅ more strenuously than the upper quantiles in large cities over China. Climate change during 1971–2018 was projected to increase the annual mean concentration of PM₂.₅ at a degree that could be comparable with the toughest-ever clean air policy during 2013–2018 had counteracted it, as inferred from the decline in the daily concentration of carbon monoxide as an inert gas. Our estimate of the impact of climate change on PM₂.₅ is higher than previous statistical models, suggesting that aerosol chemistry might play a more important role than previously thought in the interaction between climate change and air pollution. Our result indicated that air quality might degrade if the future synoptic climate change could continue interacting with aerosol chemistry as it had occurred in the past half-century.
    Keywords aerosols ; air ; air pollution ; air quality ; carbon monoxide ; climate ; climate change ; issues and policy ; meteorology ; statistical models ; technology ; China
    Language English
    Dates of publication 2022-0726
    Size p. 11199-11211.
    Publishing place American Chemical Society
    Document type Article
    ISSN 1520-5851
    DOI 10.1021/acs.est.1c08403
    Database NAL-Catalogue (AGRICOLA)

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  3. Article ; Online: Stringent Emission Controls Are Needed to Reach Clean Air Targets for Cities in China under a Warming Climate.

    Wang, Rong / Yang, Yechen / Xing, Xiaofan / Wang, Lin / Chen, Jianmin / Tang, Xu / Cao, Junji / Morawska, Lidia / Balkanski, Yves / Hauglustaine, Didier / Ciais, Philippe / Ma, Jianmin

    Environmental science & technology

    2022  Volume 56, Issue 16, Page(s) 11199–11211

    Abstract: Quantifying the threat that climate change poses to fine particle ( ... ...

    Abstract Quantifying the threat that climate change poses to fine particle (PM
    MeSH term(s) Aerosols ; Air Pollutants/analysis ; Air Pollution/analysis ; China ; Cities ; Environmental Monitoring ; Gases ; Particulate Matter/analysis
    Chemical Substances Aerosols ; Air Pollutants ; Gases ; Particulate Matter
    Language English
    Publishing date 2022-07-26
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1520-5851
    ISSN (online) 1520-5851
    DOI 10.1021/acs.est.1c08403
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Computing Investigations of Molecular and Atomic Vibrations of Ice IX.

    Zhao, Zeng-Ji / Qin, Xiao-Ling / Cao, Jing-Wen / Zhu, Xu-Liang / Yang, Ye-Chen / Wang, Hao-Cheng / Zhang, Peng

    ACS omega

    2019  Volume 4, Issue 20, Page(s) 18936–18941

    Abstract: The normal modes of ice IX were investigated using the CASTEP code package, which is based on density functional theory. We found that the translational modes could be divided into three categories: four-bond vibrations, which possessed the highest ... ...

    Abstract The normal modes of ice IX were investigated using the CASTEP code package, which is based on density functional theory. We found that the translational modes could be divided into three categories: four-bond vibrations, which possessed the highest energy; two-bond vibrations, which possessed the medium energy; and cluster vibrations with the lowest energy. The former two categories represent monomers vibrating against neighbors and present as two distinct peaks in many ice phases recorded in inelastic neutron-scattering experiments. It is typically difficult to assign the molecular vibration peaks in the far infrared region. The method we developed to analyze the normal modes, especially in the translation band of ice IX, provided physical insights into the vibrational spectrum of ice.
    Language English
    Publishing date 2019-10-30
    Publishing country United States
    Document type Journal Article
    ISSN 2470-1343
    ISSN (online) 2470-1343
    DOI 10.1021/acsomega.9b03190
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Spatially explicit analysis identifies significant potential for bioenergy with carbon capture and storage in China.

    Xing, Xiaofan / Wang, Rong / Bauer, Nico / Ciais, Philippe / Cao, Junji / Chen, Jianmin / Tang, Xu / Wang, Lin / Yang, Xin / Boucher, Olivier / Goll, Daniel / Peñuelas, Josep / Janssens, Ivan A / Balkanski, Yves / Clark, James / Ma, Jianmin / Pan, Bo / Zhang, Shicheng / Ye, Xingnan /
    Wang, Yutao / Li, Qing / Luo, Gang / Shen, Guofeng / Li, Wei / Yang, Yechen / Xu, Siqing

    Nature communications

    2021  Volume 12, Issue 1, Page(s) 3159

    Abstract: As China ramped-up coal power capacities rapidly while ... ...

    Abstract As China ramped-up coal power capacities rapidly while CO
    Language English
    Publishing date 2021-05-26
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-021-23282-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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