LIVIVO - Search results -

Search results

Result 1 - 10 of total 32

Search options

Article: Sexual Dimorphism in the Limb Bones of Asiatic Toad (

Yan, Chengzhi / Ma, Hui / Yang, Yuejun / Mi, Zhiping

Animals : an open access journal from MDPI

2023 Volume 13, Issue 16

Abstract: Sexual dimorphism is often considered to be the result of differences in the intensity of sexual selection between sexes. From this point of view, the sexual dimorphism of the limb bones of ... ...

Abstract	Sexual dimorphism is often considered to be the result of differences in the intensity of sexual selection between sexes. From this point of view, the sexual dimorphism of the limb bones of the
Language	English
Publishing date	2023-08-16
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2606558-7
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani13162638
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Metabolic Adaption of Flexor Carpi Radialis to Amplexus Behavior in Asiatic Toads (

Yan, Chengzhi / Ma, Hui / Yang, Yuejun / Mi, Zhiping

International journal of molecular sciences

2023 Volume 24, Issue 12

Abstract: Amplexus is a type of mating behavior among toads that is essential for successful external fertilization. Most studies have primarily focused on the behavioral diversity of amplexus, and less is known regarding the metabolic changes occurring in ... ...

Abstract	Amplexus is a type of mating behavior among toads that is essential for successful external fertilization. Most studies have primarily focused on the behavioral diversity of amplexus, and less is known regarding the metabolic changes occurring in amplectant males. The aim of this study was to compare the metabolic profiles of amplectant Asiatic toad (
MeSH term(s)	Animals ; Male ; Adaptation, Physiological ; Amino Acids/analysis ; Amino Acids/metabolism ; Bufonidae/metabolism ; Carbohydrate Metabolism ; Carbohydrates/analysis ; Energy Metabolism ; Forelimb ; Lipid Metabolism ; Metabolome ; Muscle, Skeletal/metabolism ; Sexual Behavior, Animal
Chemical Substances	Amino Acids ; Carbohydrates
Language	English
Publishing date	2023-06-15
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms241210174
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Sexual Dimorphism in the Limb Bones of Asiatic Toad (Bufo gargarizans) in Relation to Sexual Selection

Yan, Chengzhi / Ma, Hui / Yang, Yuejun / Mi, Zhiping

Animals. 2023 Aug. 16, v. 13, no. 16

2023

Abstract	Sexual dimorphism is often considered to be the result of differences in the intensity of sexual selection between sexes. From this point of view, the sexual dimorphism of the limb bones of the Bufo gargarizans in southwest China was studied. Results showed that the fore- and hindlimb skeletons of this species were sexually dimorphic in anatomy. The humerus, radioulna, and total lengths of the forelimb skeleton of males were substantially longer than those of females, but the hand length of males was smaller than that of females. Several other features of males, such as deltoid and medial crest areas and humerus and radioulnar weights, were also significantly larger than those of females. The femoris, tibiofibula, talus–calcaneus, and foot lengths; total hindlimb skeleton length; and femoral upper crest areas of males were significantly greater than those of females. However, no significant intersexual difference in femoris and tibiofibular weights was observed. These findings suggested that robust forelimb bones and long hindlimb bones could contribute to the mating success of males; if so, sexual selection promotes the evolution of sexual size and shape dimorphism in the limb bones of the B. gargarizans.
Keywords	Bufo ; hindlimbs ; humerus ; sexual dimorphism ; sexual selection ; skeleton ; toads ; China
Language	English
Dates of publication	2023-0816
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article ; Online
ZDB-ID	2606558-7
ISSN	2076-2615
ISSN	2076-2615
DOI	10.3390/ani13162638
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Article ; Online: COSA-1 mediated pro-crossover complex formation promotes meiotic crossing over in C. elegans.

Yang, Yuejun / Wang, Nan / Liu, Guoteng / Nan, Wencong / Wang, Bin / Gartner, Anton / Zhang, Hongtao / Hong, Ye

Nucleic acids research

2024

Abstract: Accurate chromosome segregation during meiosis requires the establishment of at least one crossover (CO) between each pair of homologous chromosomes. CO formation depends on a group of conserved pro-CO proteins, which colocalize at CO-designated sites ... ...

Abstract	Accurate chromosome segregation during meiosis requires the establishment of at least one crossover (CO) between each pair of homologous chromosomes. CO formation depends on a group of conserved pro-CO proteins, which colocalize at CO-designated sites during late meiotic prophase I. However, it remains unclear whether these pro-CO proteins form a functional complex and how they promote meiotic CO formation in vivo. Here, we show that COSA-1, a key component required for CO formation, interacts with other pro-CO factors, MSH-5 and ZHP-3, via its N-terminal disordered region. Point mutations that impair these interactions do not affect CO designation, but they strongly hinder the accumulation of COSA-1 at CO-designated sites and result in defective CO formation. These defects can be partially bypassed by artificially tethering an interaction-compromised COSA-1 derivate to ZHP-3. Furthermore, we revealed that the accumulation of COSA-1 into distinct foci is required to assemble functional 'recombination nodules'. These prevent early CO-designated recombination intermediates from being dismantled by the RTEL-1 helicase and protect late recombination intermediates, such as Holliday junctions, until they are resolved by CO-specific resolvases. Altogether, our findings provide insight into COSA-1 mediated pro-CO complex assembly and its contribution to CO formation.
Language	English
Publishing date	2024-02-27
Publishing country	England
Document type	Journal Article
ZDB-ID	186809-3
ISSN	1362-4962 ; 1362-4954 ; 0301-5610 ; 0305-1048
ISSN (online)	1362-4962 ; 1362-4954
ISSN	0301-5610 ; 0305-1048
DOI	10.1093/nar/gkae130
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1067: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Near-infrared laser-assisted Ag@Chi-PB nanocompounds for synergistically eradicating multidrug-resistant bacteria and promoting diabetic abscess healing.

Shen, Jingyi / Tong, Aidi / Zhong, Xianghua / Yin, Caiyun / Ahmad, Bilal / Wu, Zhou / Yang, Yuejun / Tong, Chunyi

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

2024 Volume 173, Page(s) 116311

Abstract: Chronic wound infections, particularly multidrug-resistant microbe-caused infections, have imposed severe challenges in clinical administration. The therapeutic effectiveness of the current strategy using conventional antibiotics is extremely ... ...

Abstract	Chronic wound infections, particularly multidrug-resistant microbe-caused infections, have imposed severe challenges in clinical administration. The therapeutic effectiveness of the current strategy using conventional antibiotics is extremely unsatisfactory. The development of novel treatment strategies to inhibit the infections caused by multidrug-resistant bacteria is highly desired. In this work, based on the combination of nanocompounds with the assistance of NIR laser, an antibacterial strategy was designed for MRSA-infected abscesses in diabetic mice. The nanocompounds named Ag@Chi-PB were prepared by using chitosan-coated Prussian blue (PB) as a nanocarrier for silver nanoparticles anchoring. Combined with near-infrared (NIR) laser, the nanocompounds were more efficient at killing Escherichia coli (E. coli) and Methicillin-resistant staphyllococcus aureus (MRSA) in vitro. Notably, MRSA was significantly removed in vivo and promoted diabetic abscess healing by the combined therapy of this nanocompound and NIR laser, owing to the synergistic antibacterial effect of photothermal therapy and release of Ag
MeSH term(s)	Animals ; Mice ; Abscess/drug therapy ; Silver/pharmacology ; Metal Nanoparticles/therapeutic use ; Escherichia coli ; Diabetes Mellitus, Experimental ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Infrared Rays ; Lasers ; Methicillin-Resistant Staphylococcus aureus ; Ferrocyanides
Chemical Substances	Silver (3M4G523W1G) ; ferric ferrocyanide (TLE294X33A) ; Anti-Bacterial Agents ; Ferrocyanides
Language	English
Publishing date	2024-02-26
Publishing country	France
Document type	Journal Article
ZDB-ID	392415-4
ISSN	1950-6007 ; 0753-3322 ; 0300-0893
ISSN (online)	1950-6007
ISSN	0753-3322 ; 0300-0893
DOI	10.1016/j.biopha.2024.116311
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ud II Zs.198: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Brain size predicts foraging and escaping abilities in the paddy frogs.

Chen, Chuan / Shao, Weijie / Zhu, Xin / Yang, Yuejun / Jiang, Ying / Liao, Wenbo

Integrative zoology

2022 Volume 18, Issue 5, Page(s) 958–961

Abstract: The three experiments revealed that successful individuals with spatial learning and escaping had relatively larger brains than unsuccessful ones in three species of the paddy frogs. We first provided experimental evidence for whole-brain size as a ... ...

Abstract	The three experiments revealed that successful individuals with spatial learning and escaping had relatively larger brains than unsuccessful ones in three species of the paddy frogs. We first provided experimental evidence for whole-brain size as a predictor of cognitive abilities in the paddy frogs. Our findings support the claim that brain size can reflect an animal's spatial learning and escaping abilities and enhance our understanding of larger brains evolved with better cognitive abilities in frogs.
MeSH term(s)	Animals ; Organ Size ; Brain ; Cognition ; Anura
Language	English
Publishing date	2022-12-31
Publishing country	Australia
Document type	Letter
ZDB-ID	2570656-1
ISSN	1749-4877 ; 1749-4869
ISSN (online)	1749-4877
ISSN	1749-4869
DOI	10.1111/1749-4877.12698
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Cytoprotection against Oxidative Stress by Methylnissolin-3-

Wu, Xiaohua / Xu, Jian / Cai, Yousheng / Yang, Yuejun / Liu, Yuancai / Cao, Shugeng

Molecules (Basel, Switzerland)

2021 Volume 26, Issue 13

Abstract: Astragalus ... ...

Abstract	Astragalus membranaceus
MeSH term(s)	Astragalus propinquus/chemistry ; Chromones ; Cytoprotection/drug effects ; Heme Oxygenase-1/metabolism ; Hep G2 Cells ; Humans ; Morpholines ; NF-E2-Related Factor 2/metabolism ; Oxidative Stress/drug effects ; Phytochemicals/chemistry ; Phytochemicals/pharmacology ; Signal Transduction/drug effects
Chemical Substances	Chromones ; Morpholines ; NF-E2-Related Factor 2 ; NFE2L2 protein, human ; Phytochemicals ; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (31M2U1DVID) ; HMOX1 protein, human (EC 1.14.14.18) ; Heme Oxygenase-1 (EC 1.14.14.18)
Language	English
Publishing date	2021-06-24
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules26133852
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.MO 81: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Hangover headache and its behavioral changes in rats

Lu Shiguang / Zhang Ying / Yang Yuejun / Zhang Yafang / Qin Guangcheng / Fu Qingqing / Shi Yingying / Zhang Fan / Wang Zhe / Chen Yanhe / Liu Yuancai / chen Lixue

Iranian Journal of Basic Medical Sciences, Vol 26, Iss 3, Pp 326-

2023 Volume 334

Abstract: Objective(s): The present study aims to establish and evaluate a rat model for hangover headaches caused by alcoholic drinks.Materials and Methods: Chronic migraine (CM) model rats were divided into 3 groups, and intragastrically administered alcoholic ... ...

Abstract	Objective(s): The present study aims to establish and evaluate a rat model for hangover headaches caused by alcoholic drinks.Materials and Methods: Chronic migraine (CM) model rats were divided into 3 groups, and intragastrically administered alcoholic drinks (sample A, B, or C) to simulate hangover headache attacks. The withdrawal threshold for the hind paw/face and the thermal latency of hind paw withdrawal were detected after 24 hr. Serum was collected from the periorbital venous plexus of rats in each group, and enzymatic immunoassays were used to determine the serum levels of calcitonin gene-related peptide (CGRP), substance P (SP), and nitric oxide (NO).Results: Compared with the control group, the mechanical hind paw pain threshold was significantly lower in rats administered Samples A and B after 24 hr; however, no significant difference was observed across groups for the thermal pain threshold. The mechanical threshold for periorbital pain was only significantly reduced in rats administered Sample A. Immunoassays further indicated that serum levels of SP in the group administered Sample A were significantly higher than those in the control group; the serum levels of NO and CGRP were significantly higher in the group of rats receiving Sample B.Conclusion: We successfully developed an effective and safe rat model for investigating alcohol drink induced hangover headaches. This model could be used to investigate the mechanisms associated with hangover headaches for the development of novel and promising candidates for the future treatment or prophylaxis of hangover headaches.
Keywords	alcohol ; animal ; behavior ; central nervous system - sensitization ; disease models ; hangover ; headche ; Medicine ; R
Subject code	630
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	Mashhad University of Medical Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Activation of Esterase D by FPD5 Inhibits Growth of A549 Lung Cancer Cells via JAB1/p53 Pathway.

Yao, Wen / Yang, Yuejun / Chen, Xinpeng / Cui, Xiaoling / Zhou, Bangzhao / Zhao, Baoxiang / Lin, Zhaomin / Miao, Junying

Genes

2022 Volume 13, Issue 5

Abstract: Esterase D (ESD) is widely distributed in mammals, and it plays an important role in drug metabolism, detoxification, and biomarkers and is closely related to the development of tumors. In our previous work, we found that a chemical small-molecule ... ...

Abstract	Esterase D (ESD) is widely distributed in mammals, and it plays an important role in drug metabolism, detoxification, and biomarkers and is closely related to the development of tumors. In our previous work, we found that a chemical small-molecule fluorescent pyrazoline derivative, FPD5, an ESD activator, could inhibit tumor growth by activating ESD, but its molecular mechanism is still unclear. Here, by using RNA interference (RNAi), andco-immunoprecipitation techniques, we found that ESD suppressed the nucleus exportation of p53 through reducing the interaction between p53 and JAB1. The protein level of p53 in the nucleus was upregulated and the downstream targets of p53 were found by Human Gene Expression Array. p53 inhibited the expression of
MeSH term(s)	A549 Cells ; Animals ; Carboxylesterase/metabolism ; Cell Line, Tumor ; Enzyme Activation ; Humans ; Lung Neoplasms/drug therapy ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Mammals ; Thiolester Hydrolases ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism
Chemical Substances	Tumor Suppressor Protein p53 ; Carboxylesterase (EC 3.1.1.1) ; ESD protein, human (EC 3.1.1.1) ; Thiolester Hydrolases (EC 3.1.2.-) ; s-formylglutathione hydrolase (EC 3.1.2.12)
Language	English
Publishing date	2022-04-28
Publishing country	Switzerland
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2527218-4
ISSN	2073-4425 ; 2073-4425
ISSN (online)	2073-4425
ISSN	2073-4425
DOI	10.3390/genes13050786
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Ofloxacin-loaded HMPB NPs for Klebsiella pneumoniae eradication in the surgical wound with the combination of PTT.

Liu, Tiansheng / Zhong, Guowei / Tang, Dongying / Liu, Xu / Fan, Jialong / Zhong, Xianghua / Yang, Yuejun / Tong, Chunyi / Liu, Bin / Yang, Xiaoping

Biotechnology and bioengineering

2022 Volume 119, Issue 7, Page(s) 1949–1964

Abstract: Klebsiella pneumoniae (K. pneumoniae) is a common bacterium whose drug-resistant can cause surgical failures and incurable infections in hospital patients. Thus, how to reverse or delay the resistance induction has become a great challenge for ... ...

Abstract	Klebsiella pneumoniae (K. pneumoniae) is a common bacterium whose drug-resistant can cause surgical failures and incurable infections in hospital patients. Thus, how to reverse or delay the resistance induction has become a great challenge for development antiresistant drug. Recently, the combination of nanomaterial-loaded antibiotics with photothermal therapy showed the efficient antibacteria ability under a low dosage of antibiotics. In this study, a nanocomposite of HMPB NPs with inherent photothermal therapy capability was used to eradicate K. pneumoniae after loading with Ofloxacin, an antibiotic against K. pneumoniae in vitro and in vivo. The nanocomplexes named as Ofloxacin@HMPB@HA NPs showed a higher effect against K. pneumoniae by destroying cell integrity and inducing ATP leakage with the assistance of laser irradiation, compared with sole Ofloxacin@HMPB@HA NPs or laser irradiation. Surgical wound infection assay further demonstrated the efficient killing K. pneumoniae and promoting the formation of new tissues, as well, which was reflected by the rapid healing of surgical wound. In summary, these results indicate the great potential of this combinational tactic based on Ofloxacin@HMPB@HA NPs for preventing the failure caused by K. pneumoniae infection.
MeSH term(s)	Anti-Bacterial Agents/pharmacology ; Humans ; Klebsiella Infections/drug therapy ; Klebsiella Infections/microbiology ; Klebsiella pneumoniae ; Ofloxacin/pharmacology ; Ofloxacin/therapeutic use ; Surgical Wound/drug therapy
Chemical Substances	Anti-Bacterial Agents ; Ofloxacin (A4P49JAZ9H)
Language	English
Publishing date	2022-04-09
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	280318-5
ISSN	1097-0290 ; 0006-3592
ISSN (online)	1097-0290
ISSN	0006-3592
DOI	10.1002/bit.28092
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.B 960: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

To top

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito