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Article ; Online: Application of metabolic GM (1,1,th,p) power model in fresh e-commerce prediction

Liu Jiefang / Yang Rongrong

SHS Web of Conferences, Vol 166, p

2023 Volume 01064

Abstract: Aiming at the prediction problem of fresh e-commerce industry, this paper attempts to combine the metabolic theory with the improved GM (1,1) power model. The article introduces the traditional GM (1,1) power model to enhance the adaptability of the ... ...

Abstract	Aiming at the prediction problem of fresh e-commerce industry, this paper attempts to combine the metabolic theory with the improved GM (1,1) power model. The article introduces the traditional GM (1,1) power model to enhance the adaptability of the model to the data series, and at the same time, a new parameter is introduced when constructing the background value, the background value is represented as a linear function of adjacent sequence points, and the form and solution method of the two specific models are given, with the goal of minimizing the average relative error, and the power exponential and new parameters are co-optimized by genetic algorithm. The optimal modeling dimension is determined through model testing, and on this basis, the metabolic GM (1,1,th,p) power model is established, and the model is applied to the prediction of the transaction scale of the fresh e-commerce industry. The results show that the improved GM (1,1) power model can significantly improve the fitting accuracy compared with the original model, and the metabolic GM(1,1,th,p) power model has good performance in the prediction problem of fresh e-commerce.
Keywords	Social Sciences ; H
Subject code	612
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Preventive and therapeutic effects of an exopolysaccharide produced by Lacticaseibacillus rhamnosus on alcoholic gastric ulcers.

Yang, Rongrong / Li, Junjun / Jiang, Chunmei / Shi, Junling

International journal of biological macromolecules

2023 Volume 235, Page(s) 123845

Abstract: Crude exopolysaccharides produced by Lacticaseibacillus rhamnosus SHA113 were previously found to exhibit anti-alcoholic gastric ulcer activity in mice, but their major active fraction, structural characteristics, and underlying mechanisms remain unknown. ...

Abstract	Crude exopolysaccharides produced by Lacticaseibacillus rhamnosus SHA113 were previously found to exhibit anti-alcoholic gastric ulcer activity in mice, but their major active fraction, structural characteristics, and underlying mechanisms remain unknown. Here, LRSE1 was identified as the active exopolysaccharide fraction produced by L. rhamnosus SHA113 responsible for the above effects. Purified LRSE1 had a molecular weight of 4.9 × 10
MeSH term(s)	Mice ; Animals ; Stomach Ulcer/chemically induced ; Stomach Ulcer/drug therapy ; Stomach Ulcer/prevention & control ; Lacticaseibacillus ; Lacticaseibacillus rhamnosus ; Phosphatidylinositol 3-Kinases ; Galactose
Chemical Substances	Phosphatidylinositol 3-Kinases (EC 2.7.1.-) ; Galactose (X2RN3Q8DNE)
Language	English
Publishing date	2023-03-01
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2023.123845
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Article ; Online: Preventive and therapeutic effects of an exopolysaccharide produced by Lacticaseibacillus rhamnosus on alcoholic gastric ulcers

Yang, Rongrong / Li, Junjun / Jiang, Chunmei / Shi, Junling

International Journal of Biological Macromolecules. 2023 Apr., v. 235 p.123845-

2023

Abstract	Crude exopolysaccharides produced by Lacticaseibacillus rhamnosus SHA113 were previously found to exhibit anti-alcoholic gastric ulcer activity in mice, but their major active fraction, structural characteristics, and underlying mechanisms remain unknown. Here, LRSE1 was identified as the active exopolysaccharide fraction produced by L. rhamnosus SHA113 responsible for the above effects. Purified LRSE1 had a molecular weight of 4.9 × 10⁴ Da and was comprised of L-fucose, D-mannose, D-glucuronic acid, d-glucose, D-galactose, and L-arabinose in the molar ratio of 2.4:6.5:1.2:1.00:0.3:0.6, respectively. The oral administration of LRSE1 resulted in a significant protective and therapeutic effect on alcoholic gastric ulcers in mice. These effects were identified to involve a reduction in reactive oxygen species, apoptosis, and the inflammatory response, increases in antioxidant enzyme activities, and increases in the phylum Firmicutes and decreases in the genera Enterococcus, Enterobacter, and Bacteroides in the gastric mucosa of mice. In vitro experiments showed that the administration of LRSE1 both inhibited apoptosis in GEC-1 cells via the TRPV1-P65-Bcl-2 pathway and inhibited the inflammatory response in RAW264.7 cells via the TRPV1-PI3K pathway. For the first time, we have identified the active exopolysaccharide fraction produced by Lacticaseibacillus that protects against alcoholic gastric ulcers and determined that its effect involves TRPV1-mediated pathways.
Keywords	Bacteroides ; Enterobacter ; Enterococcus ; antioxidant enzymes ; apoptosis ; arabinose ; exopolysaccharides ; fucose ; galactose ; gastric mucosa ; glucose ; glucuronic acid ; inflammation ; mannose ; molecular weight ; oral administration ; reactive oxygen species ; stomach ulcers ; Alcoholic gastric ulcer ; Gastric flora ; Transientreceptorpotentialvanilloid-1 ; lactic acid bacteria
Language	English
Dates of publication	2023-04
Publishing place	Elsevier B.V.
Document type	Article ; Online
ZDB-ID	282732-3
ISSN	1879-0003 ; 0141-8130
ISSN (online)	1879-0003
ISSN	0141-8130
DOI	10.1016/j.ijbiomac.2023.123845
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Article: Assessing the risk of prenatal depressive symptoms in Chinese women: an integrated evaluation of serum metabolome, multivitamin supplement intake, and clinical blood indicators.

Yang, Rongrong / Lin, Zhenguo / Cai, Yanhua / Chen, Nan / Zhou, Ying / Zhang, Jie / Hong, Guolin

Frontiers in psychiatry

2024 Volume 14, Page(s) 1234461

Abstract: Background: Prenatal depressive symptoms (PDS) is a serious public health problem. This study aimed to develop an integrated panel and nomogram to assess at-risk populations by examining the association of PDS with the serum metabolome, multivitamin ... ...

Abstract	Background: Prenatal depressive symptoms (PDS) is a serious public health problem. This study aimed to develop an integrated panel and nomogram to assess at-risk populations by examining the association of PDS with the serum metabolome, multivitamin supplement intake, and clinical blood indicators. Methods: This study comprised 221 pregnant women, categorized into PDS and non-PDS groups based on the Edinburgh postnatal depression scale. The participants were divided into training and test sets according to their enrollment time. We conducted logistic regression analysis to identify risk factors, and employed liquid chromatography/high resolution mass spectrometry-based serum metabolome analysis to identify metabolic biomarkers. Multiple factor analysis was used to combine risk factors, clinical blood indicators and key metabolites, and then a nomogram was developed to estimate the probability of PDS. Results: We identified 36 important differential serum metabolites as PDS biomarkers, mainly involved in amino acid metabolism and lipid metabolism. Multivitamin intake works as a protective factor for PDS. The nomogram model, including multivitamin intake, HDL-C and three key metabolites (histidine, estrone and valylasparagine), exhibited an AUC of 0.855 in the training set and 0.774 in the test set, and the calibration curves showed good agreement, indicating that the model had good stability. Conclusion: Our approach integrates multiple models to identify metabolic biomarkers for PDS, ensuring their robustness. Furthermore, the inclusion of dietary factors and clinical blood indicators allows for a comprehensive characterization of each participant. The analysis culminated in an intuitive nomogram based on multimodal data, displaying potential performance in initial PDS risk assessment.
Language	English
Publishing date	2024-01-11
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564218-2
ISSN	1664-0640
ISSN	1664-0640
DOI	10.3389/fpsyt.2023.1234461
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Article ; Online: A meta-analysis of the changes in the Gut microbiota in patients with intractable epilepsy compared to healthy controls.

Yang, Rongrong / Liu, Jie / Diao, Limei / Wei, Liping / Luo, Huazheng / Cai, Lun

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

2024 Volume 120, Page(s) 213–220

Abstract: Objective: To explore gut microbiota changes in intractable epilepsy patients compared to healthy control individuals through meta-analysis.: Methods: PubMed, Web of Science, CNKI, Wanfang, medRxiv, bioRxiv, ilae.org, clinical trial databases, and ... ...

Abstract	Objective: To explore gut microbiota changes in intractable epilepsy patients compared to healthy control individuals through meta-analysis. Methods: PubMed, Web of Science, CNKI, Wanfang, medRxiv, bioRxiv, ilae.org, clinical trial databases, and papers from the International Epilepsy Congress (IEC) were searched, and the literature on the correlation between intractable epilepsy and the gut microbiota reported from database establishment to June 2023 was included. Literature meeting the inclusion criteria was screened, and meta-analysis of the included literature was performed using RevMan5.4 software. Results: Ten case-control studies were included in the meta-analysis. There were 183 patients with intractable epilepsy and 283 healthy control subjects. The analysis results indicated that Bacteroidetes (MD = -0.64, 95 %-CI = -1.21 to -0.06) and Ruminococcaceae (MD = -1.44, 95 % CI = -1.96 to -0.92) were less abundant in the patients with intractable epilepsy than in the normal population. Proteobacteria (MD = 0.53, 95 % CI = 0.02 to 1.05) and Verrucomicrobia (MD = 0.26, 95 % CI = 0.06 to 0.45) were more abundant in the patients with intractable epilepsy than in the normal population. Conclusion: This meta-analysis indicated that the abundances of Bacteroidetes and Ruminococcaceae were reduced while those of Proteobacteria and Verrucomicrobia were significantly increased in patients with intractable epilepsy. The above changes in these four taxa of the gut microbiota may have been induced by intractable epilepsy, which may increase the risk of seizures. Their roles in the pathogenesis of intractable epilepsy need to be further explored, and related factors that influence microbiota changes should be considered in future studies.
MeSH term(s)	Humans ; Drug Resistant Epilepsy ; Gastrointestinal Microbiome ; Seizures ; Case-Control Studies ; Databases, Factual
Language	English
Publishing date	2024-01-29
Publishing country	Scotland
Document type	Meta-Analysis ; Journal Article ; Review
ZDB-ID	1193674-5
ISSN	1532-2653 ; 0967-5868
ISSN (online)	1532-2653
ISSN	0967-5868
DOI	10.1016/j.jocn.2024.01.023
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Article ; Online: Challenges of PICC placement via the popliteal vein under ultrasound guidance in a patient with severe burns: A case report.

Shi, Lihua / Chen, Qiyu / Yang, Rongrong / Liao, Lihong / Zhang, Jianfang / Liu, Yingchun

The journal of vascular access

2024 , Page(s) 11297298241245066

Abstract: Peripherally inserted central catheters are widely used in patients with extensive burns, with the guidelines recommending insertion through unburned skin. This case report describes a patient who was burned over 88% of their surface area and suffered ... ...

Abstract	Peripherally inserted central catheters are widely used in patients with extensive burns, with the guidelines recommending insertion through unburned skin. This case report describes a patient who was burned over 88% of their surface area and suffered severe inhalation injury. For him, the popliteal vein was the only vein on unburned skin available for catheter catheterization. Based on evidence, we successfully placed a peripherally inserted central catheter through the popliteal vein under ultrasound while the patient was in the prone position and avoided associated complications.
Language	English
Publishing date	2024-04-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	2252820-9
ISSN	1724-6032 ; 1129-7298
ISSN (online)	1724-6032
ISSN	1129-7298
DOI	10.1177/11297298241245066
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Article ; Online: Changes of peripheral lymphocyte subset in patients with SARS-CoV-2 infection during the whole course of disease.

Yu, Xingxia / Yang, Rongrong

Expert review of respiratory medicine

2020 Volume 15, Issue 4, Page(s) 553–559

Abstract: ... ...

Abstract	Background
MeSH term(s)	Adult ; Aged ; COVID-19/blood ; COVID-19/diagnosis ; Disease Progression ; Female ; Humans ; Lymphocyte Count ; Lymphocyte Subsets ; Male ; Middle Aged ; Prognosis ; Retrospective Studies
Language	English
Publishing date	2020-12-31
Publishing country	England
Document type	Journal Article
ZDB-ID	2479146-5
ISSN	1747-6356 ; 1747-6348
ISSN (online)	1747-6356
ISSN	1747-6348
DOI	10.1080/17476348.2021.1866991
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Article ; Online: COVID-19 transmission through asymptomatic carriers is a challenge to containment.

Yu, Xingxia / Yang, Rongrong

Influenza and other respiratory viruses

2020 Volume 14, Issue 4, Page(s) 474–475

MeSH term(s)	Betacoronavirus ; COVID-19 ; China ; Coronavirus ; Coronavirus Infections ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
Keywords	covid19
Language	English
Publishing date	2020-04-15
Publishing country	England
Document type	Letter ; Comment
ZDB-ID	2274538-5
ISSN	1750-2659 ; 1750-2640
ISSN (online)	1750-2659
ISSN	1750-2640
DOI	10.1111/irv.12743
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Article ; Online: Chitooligosaccharides Derivatives Protect ARPE-19 Cells against Acrolein-Induced Oxidative Injury

Yang, Cheng / Yang, Rongrong / Gu, Ming / Hao, Jiejie / Wang, Shixin / Li, Chunxia

Mar Drugs. 2023 Feb. 22, v. 21, no. 3

2023

Abstract: Age-related macular degeneration (AMD) is the leading cause of vision loss among the elderly. The progression of AMD is closely related to oxidative stress in the retinal pigment epithelium (RPE). Here, a series of chitosan oligosaccharides (COSs) and N- ... ...

Abstract	Age-related macular degeneration (AMD) is the leading cause of vision loss among the elderly. The progression of AMD is closely related to oxidative stress in the retinal pigment epithelium (RPE). Here, a series of chitosan oligosaccharides (COSs) and N-acetylated derivatives (NACOSs) were prepared, and their protective effects on an acrolein-induced oxidative stress model of ARPE-19 were explored using the MTT assay. The results showed that COSs and NACOs alleviated APRE-19 cell damage induced by acrolein in a concentration-dependent manner. Among these, chitopentaose (COS–5) and its N-acetylated derivative (N–5) showed the best protective activity. Pretreatment with COS–5 or N–5 could reduce intracellular and mitochondrial reactive oxygen species (ROS) production induced by acrolein, increase mitochondrial membrane potential, GSH level, and the enzymatic activity of SOD and GSH-Px. Further study indicated that N–5 increased the level of nuclear Nrf2 and the expression of downstream antioxidant enzymes. This study revealed that COSs and NACOSs reduced the degeneration and apoptosis of retinal pigment epithelial cells by enhancing antioxidant capacity, suggesting that they have the potential to be developed into novel protective agents for AMD treatment and prevention.
Keywords	acrolein ; antioxidant activity ; apoptosis ; chitooligosaccharides ; chitosan ; elderly ; enzyme activity ; epithelium ; macular degeneration ; membrane potential ; mitochondria ; mitochondrial membrane ; models ; oxidative stress ; oxidative toxicity ; reactive oxygen species ; toxicity testing ; vision
Language	English
Dates of publication	2023-0222
Publishing place	Multidisciplinary Digital Publishing Institute
Document type	Article ; Online
ZDB-ID	2175190-0
ISSN	1660-3397
ISSN	1660-3397
DOI	10.3390/md21030137
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Article ; Online: The association of the dietary inflammatory potential with risk of overall and site-specific cancers: A community-based longitudinal study in the UK Biobank.

Liang, Jiaxin / Yang, Rongrong / Da, Huiying / Wang, Jiao / Maimaitiyiming, Maiwulamujiang / Qi, Xiuying / Dunk, Michelle M / Xu, Weili

The journal of nutrition, health & aging

2024 Volume 28, Issue 6, Page(s) 100225

Abstract: Objectives: The association of the dietary inflammatory potential with cancer risk remains uncertain. We examined the relationship of the dietary inflammatory potential with risk of overall and site-specific cancers and explored its sex and age ... ...

Abstract	Objectives: The association of the dietary inflammatory potential with cancer risk remains uncertain. We examined the relationship of the dietary inflammatory potential with risk of overall and site-specific cancers and explored its sex and age differences. Design: A community-based longitudinal study. Setting: Participants from the UK Biobank completed baseline surveys during 2006-2010 and were followed for up to 15 years to detect incident cancer. Participants: 170,899 cancer-free participants with dietary data available (mean age: 55.73 ± 7.95, 54.10% female). Measurements: At baseline, dietary intake was assessed with a 24-h dietary record for up to 5 times. The inflammatory diet index (IDI) was calculated to assess the dietary inflammatory potential as a weighted sum of 31 food groups (including 14 anti-inflammatory and 17 pro-inflammatory) based on plasma high-sensitivity C-reactive protein (hsCRP) levels, and tertiled as low (indicating low-inflammatory diet), moderate, and high IDI (as reference). Overall and site-specific cancers were ascertained via linkage to routine hospital admission, cancer registry, and death certificate data. Data were analyzed using Cox regression and Laplace regression. Results: During the follow-up (median 10.32 years, interquartile range: 9.95-11.14 years), 18,884 (11.05%) participants developed cancer. In multi-adjusted Cox regression, low IDI scores were associated with decreased risk of rectal cancer (hazard ratio [95% confidence interval, CI] 0.76 [0.61, 0.94]), thyroid cancer [0.45 (0.27, 0.74)], lung cancer [0.73 (0.61, 0.88)]. However, the association between IDI score and the risk of overall cancer was not significant. Laplace regression analysis showed that 10th percentile differences (95% CIs) of cancer onset time for participants with low IDI scores was prolonged by 1.29 (0.32, 2.27), 1.44 (0.58, 2.30), and 2.62 (0.98, 4.27) years for rectal cancer, thyroid cancer, and lung cancer, respectively, compared to those with high IDI scores. Stratified analysis revealed that low IDI scores were associated with a lower risk of rectal cancer (p interaction between IDI score and sex = 0.035) and lung cancer in males, but not in females, and with a reduced risk of thyroid cancer in females, but not in males. Moreover, low IDI scores were associated with a reduced risk of rectal cancer and lung cancer in the participants aged ≥60 years, but not in those <60 years, and with a reduced risk of thyroid cancer in those aged ≥60 years and <60 years. Conclusions: A low-inflammatory diet is associated with decreased risk and prolonged onset time of rectal cancer and lung cancer, especially among males and individuals aged ≥60 years, and thyroid cancer among females.
Language	English
Publishing date	2024-04-05
Publishing country	France
Document type	Journal Article
ZDB-ID	2081921-3
ISSN	1760-4788 ; 1279-7707
ISSN (online)	1760-4788
ISSN	1279-7707
DOI	10.1016/j.jnha.2024.100225
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