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Article ; Online: A Parallel Spectral Element Method for Fractional Lorenz System

Yanhui Su

Discrete Dynamics in Nature and Society, Vol

2015 Volume 2015

Abstract: We provide a parallel spectral element method for the fractional Lorenz system numerically. The detailed construction and implementation of the method are presented. Thanks to the spectral accuracy of the presented method, the storage requirement due to ... ...

Abstract	We provide a parallel spectral element method for the fractional Lorenz system numerically. The detailed construction and implementation of the method are presented. Thanks to the spectral accuracy of the presented method, the storage requirement due to the “global time dependence” can be considerably relaxed. Also, the parareal method combining spectral element method reduces the computing time greatly. Finally, we have tested the chaotic behaviors of fractional Lorenz system. Our numerical results are in excellent agreement with the results from other numerical methods.
Keywords	Mathematics ; QA1-939 ; Social sciences (General) ; H1-99
Language	English
Publishing date	2015-01-01T00:00:00Z
Publisher	Hindawi Publishing Corporation
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A Parallel Spectral Element Method for Fractional Lorenz System

Yanhui Su

Discrete Dynamics in Nature and Society, Vol

2015 Volume 2015

Keywords	Social sciences (General) ; H1-99 ; Social Sciences ; H ; Mathematics ; QA1-939 ; Science ; Q
Language	English
Publishing date	2015-01-01T00:00:00Z
Publisher	Hindawi Publishing Corporation
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Hydrophobically Associating Polymers Dissolved in Seawater for Enhanced Oil Recovery of Bohai Offshore Oilfields

Fei Yi / Bo Huang / Chengsheng Wang / Xiaoxu Tang / Xiujun Wang / Quangang Liu / Yanhui Su / Shijia Chen / Xiaoyan Wu / Bin Chen / Jing Zhang / Dianguo Wu / Shuai Yu / Yujun Feng / Xin Su

Molecules, Vol 27, Iss 2744, p

2022 Volume 2744

Abstract: As compared to China’s overall oil reserves, the reserve share of offshore oilfields is rather significant. However, offshore oilfield circumstances for enhanced oil recovery (EOR) include not just severe temperatures and salinity, but also restricted ... ...

Abstract	As compared to China’s overall oil reserves, the reserve share of offshore oilfields is rather significant. However, offshore oilfield circumstances for enhanced oil recovery (EOR) include not just severe temperatures and salinity, but also restricted space on offshore platforms. This harsh oil production environment requires polymers with relatively strong salt resistance, solubility, thickening ability, rapid, superior injection capabilities, and anti-shearing ability. As a result, research into polymers with high viscosity and quick solubility is recognized as critical to meeting the criteria of polymer flooding in offshore oil reservoirs. For the above purposes, a novel hydrophobically associating polymer (HAP) was prepared to be used for polymer flooding of Bohai offshore oilfields. The synthetic procedure was free radical polymerization in aqueous solutions starting at 0 °C, using acrylamide (AM), acrylic acid (AA), 2-acrylamido-2-methylpropane sulfonic acid (AMPS), and poly(ethylene glycol) octadecyl methacrylate (POM) as comonomers. It was discovered that under ideal conditions, the molecular weight of HAP exceeds 2.1 × 10 7 g⋅mol −1 . In a simulated reservoir environment, HAP has substantially greater solubility, thickening property, and salt resistance than conventional polyacrylamide (HPAM), with equivalent molecular weight. Finally, the injectivity and propagation of the two polymers in porous media were investigated. Compared with HPAM, which has a similar molecular weight, HAP solution with the concentration of 0.175% had a much better oil displacement effect in the porous medium, which can enhance oil recovery by 8.8%. These discoveries have the potential to pave the way for chemical EOR in offshore oilfields.
Keywords	hydrophobically associating polymers ; sea water ; viscosity ; enhanced oil recovery ; polymerization ; Organic chemistry ; QD241-441
Subject code	660 ; 333
Language	English
Publishing date	2022-04-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Conditional Loss of the Exocyst Component Exoc5 in Retinal Pigment Epithelium (RPE) Results in RPE Dysfunction, Photoreceptor Cell Degeneration, and Decreased Visual Function

Bärbel Rohrer / Manas R. Biswal / Elisabeth Obert / Yujing Dang / Yanhui Su / Xiaofeng Zuo / Ben Fogelgren / Altaf A. Kondkar / Glenn P. Lobo / Joshua H. Lipschutz

International Journal of Molecular Sciences, Vol 22, Iss 5083, p

2021 Volume 5083

Abstract: To characterize the mechanisms by which the highly conserved exocyst trafficking complex regulates eye physiology in zebrafish and mice, we focused on Exoc5 (also known as sec10 ), a central exocyst component. We analyzed both exoc5 zebrafish mutants and ...

Abstract	To characterize the mechanisms by which the highly conserved exocyst trafficking complex regulates eye physiology in zebrafish and mice, we focused on Exoc5 (also known as sec10 ), a central exocyst component. We analyzed both exoc5 zebrafish mutants and retinal pigmented epithelium (RPE)-specific Exoc5 knockout mice. Exoc5 is present in both the non-pigmented epithelium of the ciliary body and in the RPE. In this study, we set out to establish an animal model to study the mechanisms underlying the ocular phenotype and to establish if loss of visual function is induced by postnatal RPE Exoc5-deficiency. Exoc5 −/− zebrafish had smaller eyes, with decreased number of melanocytes in the RPE and shorter photoreceptor outer segments. At 3.5 days post-fertilization, loss of rod and cone opsins were observed in zebrafish exoc5 mutants. Mice with postnatal RPE-specific loss of Exoc5 showed retinal thinning associated with compromised visual function and loss of visual photoreceptor pigments. Abnormal levels of RPE65 together with a reduced c-wave amplitude indicate a dysfunctional RPE. The retinal phenotype in Exoc5 −/− mice was present at 20 weeks, but was more pronounced at 27 weeks, indicating progressive disease phenotype. We previously showed that the exocyst is necessary for photoreceptor ciliogenesis and retinal development. Here, we report that exoc5 mutant zebrafish and mice with RPE-specific genetic ablation of Exoc5 develop abnormal RPE pigmentation, resulting in retinal cell dystrophy and loss of visual pigments associated with compromised vision. Together, these data suggest that exocyst-mediated signaling in the RPE is required for RPE structure and function, indirectly leading to photoreceptor degeneration.
Keywords	retinal pigmented epithelium ; exocyst complex component 5 ; photoreceptor ; visual function ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Subject code	630
Language	English
Publishing date	2021-05-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Wax‐Transferred Hydrophobic CVD Graphene Enables Water‐Resistant and Dendrite‐Free Lithium Anode toward Long Cycle Li–Air Battery

Yong Ma / Pengwei Qi / Jun Ma / Le Wei / Liang Zhao / Jian Cheng / Yanhui Su / Yuting Gu / Yuebin Lian / Yang Peng / Yanbin Shen / Liwei Chen / Zhao Deng / Zhongfan Liu

Advanced Science, Vol 8, Iss 16, Pp n/a-n/a (2021)

2021

Abstract: Abstract One of the key challenges in achieving practical lithium–air battery is the poor moisture tolerance of the lithium metal anode. Herein, guided by theoretical modeling, an effective tactic for realizing water‐resistant Li anode by implementing a ... ...

Abstract	Abstract One of the key challenges in achieving practical lithium–air battery is the poor moisture tolerance of the lithium metal anode. Herein, guided by theoretical modeling, an effective tactic for realizing water‐resistant Li anode by implementing a wax‐assisted transfer protocol is reported to passivate the Li surface with an inert high‐quality chemical vapor deposition (CVD) graphene layer. This electrically conductive and mechanically robust graphene coating enables serving as an artificial solid/electrolyte interphase (SEI), guiding homogeneous Li plating/stripping, suppressing dendrite and “dead” Li formation, as well as passivating the Li surface from moisture erosion and side reactions. Consequently, lithium–air batteries fabricated with the passivated Li anodes demonstrate a superb cycling performance up to 2300 h (230 cycles at 1000 mAh g−1, 200 mA g−1). More strikingly, the anode recycled thereafter can be recoupled with a fresh cathode to continuously run for 400 extended hours. Comprehensive time‐lapse and ex situ microscopic and spectroscopic investigations are further carried out for elucidating the fundamentals behind the extraordinary air and electrochemical stability.
Keywords	artificial solid/electrolyte interphase ; chemical vapor depositio‐grown graphene ; lithium–air batteries ; water‐resistant anodes ; Science ; Q
Subject code	600
Language	English
Publishing date	2021-08-01T00:00:00Z
Publisher	Wiley
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Exercise alleviates cardiac remodelling in diabetic cardiomyopathy via the miR-486a-5p-Mst1 pathway

Dong Sun / Haichang Wang / Yanhui Su / Jie Lin / Mingming Zhang / Wanrong Man / Xinglong Song / Liang Zhang / Baolin Guo / Kaikai Hao / Dongdong Sun

Iranian Journal of Basic Medical Sciences, Vol 24, Iss 2, Pp 150-

2021 Volume 159

Abstract: Objective(s): Physical exercise has emerged as an effective therapy to mitigate cardiac remodelling in diabetic cardiomyopathy (DCM). The results of our previous studies revealed mammalian sterile 20-like kinase 1 (Mst1) is a key regulator of the ... ...

Abstract	Objective(s): Physical exercise has emerged as an effective therapy to mitigate cardiac remodelling in diabetic cardiomyopathy (DCM). The results of our previous studies revealed mammalian sterile 20-like kinase 1 (Mst1) is a key regulator of the progression of DCM. However, the precise molecular mechanism of physical exercise-induced cardiac protection and its association with Mst1 inhibition remain unclear. Materials and Methods: Wildtype and Mst1 transgenic mice were challenged with streptozotocin (STZ) to induce experimental diabetes and were divided into sedentary and exercise groups. The DCM phenotype was evaluated by echocardiography, Masson’s trichrome staining, TUNEL and immunoblotting analyses. The exercise-regulated miRNAs targeting Mst1 were predicted by bioinformatic analysis and later confirmed by RT-qPCR, immunoblotting, and dual-luciferase reporter assays. In addition, cultured neonatal mouse cardiomyocytes were subjected to simulate diabetes to elucidate the underlying mechanisms. Results: Compared to the sedentary diabetic control, physical exercise inhibited Mst1 and alleviated cardiac remodelling in mice with DCM, as evidenced by decreases in the left ventricular end-systolic internal dimension (LVESD) and left ventricular end-diastolic internal dimension (LVEDD), increases in the left ventricular ejection fraction (LVEF) and left ventricular fractional shortening (LVFS), attenuation of collagen deposition, and the suppression of apoptosis. Bioinformatic analysis and apoptosis assessments revealed exercise exerted protective effects against DCM through miR-486a-5p release. Moreover, luciferase reporter assays confirmed miR-486a-5p directly suppressed the expression of Mst1, thereby inhibiting the apoptosis of cardiomyocytes subjected to high glucose treatment. Conclusion: Physical exercise inhibits cardiac remodelling in DCM, and the mechanism is associated with miR-486a-5p release-induced Mst1 inhibition.
Keywords	apoptosis diabetic cardiomyopathy exercise mst1 (stk4) mir ; 486a ; 5p ; Medicine ; R
Subject code	796
Language	English
Publishing date	2021-02-01T00:00:00Z
Publisher	Mashhad University of Medical Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A Functional Binding Domain in the Rbpr2 Receptor Is Required for Vitamin A Transport, Ocular Retinoid Homeostasis, and Photoreceptor Cell Survival in Zebrafish

Ashish K. Solanki / Altaf A. Kondkar / Joseph Fogerty / Yanhui Su / Seok-Hyung Kim / Joshua H. Lipschutz / Deepak Nihalani / Brian D. Perkins / Glenn P. Lobo

Cells, Vol 9, Iss 1099, p

2020 Volume 1099

Abstract: Dietary vitamin A/all- trans retinol/ROL plays a critical role in human vision. ROL circulates bound to the plasma retinol-binding protein (RBP4) as RBP4-ROL. In the eye, the STRA6 membrane receptor binds to circulatory RBP4 and internalizes ROL. STRA6 ... ...

Abstract	Dietary vitamin A/all- trans retinol/ROL plays a critical role in human vision. ROL circulates bound to the plasma retinol-binding protein (RBP4) as RBP4-ROL. In the eye, the STRA6 membrane receptor binds to circulatory RBP4 and internalizes ROL. STRA6 is, however, not expressed in systemic tissues, where there is high affinity RBP4 binding and ROL uptake. We tested the hypothesis that the second retinol binding protein 4 receptor 2 (Rbpr2), which is highly expressed in systemic tissues of zebrafish and mouse, contains a functional RBP4 binding domain, critical for ROL transport. As for STRA6, modeling and docking studies confirmed three conserved RBP4 binding residues in zebrafish Rbpr2. In cell culture studies, disruption of the RBP4 binding residues on Rbpr2 almost completely abolished uptake of exogenous vitamin A. CRISPR-generated rbpr2- RBP4 domain zebrafish mutants showed microphthalmia, shorter photoreceptor outer segments, and decreased opsins, which were attributed to impaired ocular retinoid content. Injection of WT-Rbpr2 mRNA into rbpr2 mutant or all- trans retinoic acid treatment rescued the mutant eye phenotypes. In conclusion, zebrafish Rbpr2 contains a putative extracellular RBP4-ROL ligand-binding domain, critical for yolk vitamin A transport to the eye for ocular retinoid production and homeostasis, for photoreceptor cell survival.
Keywords	retinol binding protein 4 receptor 2 ; RBP4 ; Rbpr2 ; STRA6 ; all- trans retinol transport ; photoreceptor cell ; Biology (General) ; QH301-705.5
Language	English
Publishing date	2020-04-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Identification and expression analysis of the interferon-induced protein with tetratricopeptide repeats 5 (IFIT5) gene in duck (Anas platyrhynchos domesticus).

Bin Wang / Yang Chen / Chunyu Mu / Yanhui Su / Ran Liu / Zhengyang Huang / Yang Li / Qingming Yu / Guobin Chang / Qi Xu / Guohong Chen

PLoS ONE, Vol 10, Iss 3, p e

2015 Volume 0121065

Abstract: The interferon-induced proteins with tetratricopeptide repeats (IFITs) protein family mediates antiviral effects by inhibiting translation initiation, cell proliferation, and migration in the interferon (IFN) dependent innate immune system. Several ... ...

Abstract	The interferon-induced proteins with tetratricopeptide repeats (IFITs) protein family mediates antiviral effects by inhibiting translation initiation, cell proliferation, and migration in the interferon (IFN) dependent innate immune system. Several members of this family, including IFIT1, IFIT2, IFIT3 and IFIT5, have been heavily studied in mammals. Avian species contain only one family member, IFIT5, and little is known about the role of this protein in birds. In this study, duck IFIT5 (duIFIT5) full-length mRNA was cloned by reverse transcription polymerase chain reaction (RT-PCR) and rapid amplification of the cDNA ends (RACE). Based on the sequence obtained, we performed a series of bioinformatics analyses, and found that duIFIT5 was most similar to homologs in other avian species. Also, duIFIT5 contained eight conserved TPR motifs and two conserved multi-domains (TPR_11 and TPR_12). Finally, we used duck hepatitis virus type 1 (DHV-1) and polyriboinosinicpolyribocytidylic acid (poly (I:C)) as a pathogen or a pathogen-associated molecular pattern induction to infect three-day-old domestic ducklings. The liver and spleen were collected to detect the change in duIFIT5 transcript level upon infection by quantitative real-time PCR (qRT-PCR). DuIFIT5 expression rapidly increased after DHV-1 infection and maintained a high level, while the transcripts of duIFIT5 peaked at 8h after poly (I:C) infection and then returned to normal. Taken together, these results provide a greater understanding of avian IFIT5.
Keywords	Medicine ; R ; Science ; Q
Language	English
Publishing date	2015-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: A post-developmental genetic screen for zebrafish models of inherited liver disease.

Seok-Hyung Kim / Shu-Yu Wu / Jeong-In Baek / Soo Young Choi / Yanhui Su / Charles R Flynn / Joshua T Gamse / Kevin C Ess / Gary Hardiman / Joshua H Lipschutz / Naji N Abumrad / Don C Rockey

PLoS ONE, Vol 10, Iss 5, p e

2015 Volume 0125980

Abstract: Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease such as simple steatosis, nonalcoholic steatohepatitis (NASH), cirrhosis and fibrosis. However, the molecular pathogenesis and genetic variations causing ... ...

Abstract	Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease such as simple steatosis, nonalcoholic steatohepatitis (NASH), cirrhosis and fibrosis. However, the molecular pathogenesis and genetic variations causing NAFLD are poorly understood. The high prevalence and incidence of NAFLD suggests that genetic variations on a large number of genes might be involved in NAFLD. To identify genetic variants causing inherited liver disease, we used zebrafish as a model system for a large-scale mutant screen, and adopted a whole genome sequencing approach for rapid identification of mutated genes found in our screen. Here, we report on a forward genetic screen of ENU mutagenized zebrafish. From 250 F2 lines of ENU mutagenized zebrafish during post-developmental stages (5 to 8 days post fertilization), we identified 19 unique mutant zebrafish lines displaying visual evidence of hepatomegaly and/or steatosis with no developmental defects. Histological analysis of mutants revealed several specific phenotypes, including common steatosis, micro/macrovesicular steatosis, hepatomegaly, ballooning, and acute hepatocellular necrosis. This work has identified multiple post-developmental mutants and establishes zebrafish as a novel animal model for post-developmental inherited liver disease.
Keywords	Medicine ; R ; Science ; Q
Subject code	571
Language	English
Publishing date	2015-01-01T00:00:00Z
Publisher	Public Library of Science (PLoS)
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Characteristics and comprehensive utilization of Litsea cubeba (Lour.) Pers.

Xue Haijun, Productivity Promotion Center in Lechang，Lechang (China) / Xiao Yanhui, Shaoguan University, Shaoguan(China), YingDong Biological Engineering Institute / He Jinming, Shaoguan University, Shaoguan(China), YingDong Biological Engineering Institute

Journal of Anhui Agricultural Sciences

Jul. 2010 , Issue (19)

Abstract: 介绍了山苍子的植物学特征、生物学特性和利用途径，为推动山苍子的综合开发利用提供了依据。 ...

Abstract	介绍了山苍子的植物学特征、生物学特性和利用途径，为推动山苍子的综合开发利用提供了依据。
Keywords	USES ; XANTHIUM ; UTILISATION ; XANTHIUM ; USOS ; XANTHIUM ; http://www.fao.org/aos/agrovoc#c_8117 ; http://www.fao.org/aos/agrovoc#c_26747
Language	zho
Document type	Article
ISSN	0517-6611
Database	AGRIS - International Information System for the Agricultural Sciences and Technology

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