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  1. Article: Collision metastasis from prostate adenocarcinoma and pancreatic ductal adenocarcinoma to a lung nodule.

    Mohamed, Ahmed / Yao, Mark / Saw, Sonia / Clark, Amanda / Madaan, Sanjeev

    JRSM open

    2023  Volume 14, Issue 3, Page(s) 20542704231153562

    Abstract: Introduction: Prostate cancer and pancreatic cancer are often complex pathologies that affect millions of patients worldwide. However, the incidence of a distant collision metastasis of both malignancies remains a rare and often poorly documented ... ...

    Abstract Introduction: Prostate cancer and pancreatic cancer are often complex pathologies that affect millions of patients worldwide. However, the incidence of a distant collision metastasis of both malignancies remains a rare and often poorly documented incidence.
    Case presentation: A 75-year-old male patient with past history of prostate cancer on maximal androgen blockade was recently diagnosed with pancreatic cancer for which he underwent radical surgical resection of pancreas with curative intent. A metastatic lung nodule was noted on surveillance CT imaging and, subsequently, biopsied. A diagnosis of collision metastasis from two distinct primary malignancies was histopathologically confirmed following immunohistochemical evaluation.
    Conclusion: We report the first case of collision metastasis of prostate and pancreatic adenocarcinomata to a lung nodule to the best of our knowledge.
    Language English
    Publishing date 2023-03-07
    Publishing country England
    Document type Case Reports
    ZDB-ID 2762955-7
    ISSN 2054-2704
    ISSN 2054-2704
    DOI 10.1177/20542704231153562
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: How international is the International Prostate Symptom Score? A literature review of validated translations of the IPSS, the most widely used self-administered patient questionnaire for male lower urinary tract symptoms.

    Yao, Mark W / Green, James S A

    Lower urinary tract symptoms

    2021  Volume 14, Issue 2, Page(s) 92–101

    Abstract: Objectives: The International Prostate Symptom Score (IPSS) approaches its 30th anniversary. This ubiquitous clinical assessment tool is a standard in the assessment and research of lower urinary tract symptoms in men. The authors explore its history, ... ...

    Abstract Objectives: The International Prostate Symptom Score (IPSS) approaches its 30th anniversary. This ubiquitous clinical assessment tool is a standard in the assessment and research of lower urinary tract symptoms in men. The authors explore its history, development, and subsequent dissemination through validated translations across the world. An estimated global coverage is calculated and mapped according to language population.
    Methods: Embase and Medline literature searches were performed, with further hand searches of grey literature and online resources. Twenty-two abstracts and journal articles validating language translations of the IPSS were reviewed in full and tabulated. Language population data were gathered from an official database and mapped.
    Results: The IPSS is available in 53 languages. Twenty-seven languages have statistically or clinically validated translations for use in male patients. This corresponds to a conservative estimate of global population coverage of approximately 2.3 billion men, or 60% of the worldwide male population. Translation methodology involves forward and back translation. Statistical validation is performed with control patients. Cronbach's alpha is used for internal consistency, and Spearman's coefficient (p) or Pearson's coefficient (r) for test-retest reliability. Issues such as the emergence of altered versions deviating from original validated translations and translation difficulties due to cultural differences are observed. Further translational work is needed to validate versions of the IPSS in languages of the developing world.
    Conclusions: The IPSS is the most prevalent patient-administered questionnaire used in urology across the world. There is no other clinical tool seen to have similar coverage. This paper aims to provide a roadmap for future clinical tools to acquire a similar level of translation and dissemination.
    MeSH term(s) Humans ; Lower Urinary Tract Symptoms/diagnosis ; Male ; Prostate ; Reproducibility of Results ; Surveys and Questionnaires ; Translations
    Language English
    Publishing date 2021-11-03
    Publishing country Australia
    Document type Journal Article ; Review
    ZDB-ID 2519111-1
    ISSN 1757-5672 ; 1757-5664
    ISSN (online) 1757-5672
    ISSN 1757-5664
    DOI 10.1111/luts.12415
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Impact of definitions on continence outcomes in a series of 1000 robot-assisted radical prostatectomies, time for an internationally agreed definition?

    Abuelnaga, Mahmoud / Gendy, Rasha / Yao, Mark / Phelan, Curtis / Pain, Julie / Wang, Wanxin / Ajzajian, Jirayr / Liu, Timing / Hassaballa, Aly Sherif / Challacombe, Ben / Kommu, Sashi / Eddy, Ben

    BJU international

    2024  

    Language English
    Publishing date 2024-03-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 1462191-5
    ISSN 1464-410X ; 1464-4096 ; 1358-8672
    ISSN (online) 1464-410X
    ISSN 1464-4096 ; 1358-8672
    DOI 10.1111/bju.16327
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Distal feeding-bowel stimulation to treat short-term or long-term pathology: a systematic review.

    Dilke, Stella Maye / Gould, Laura / Yao, Mark / Souvatzi, Maria / Stearns, Adam / Ignjatovic-Wilson, Ana / Tozer, Phil / Vaizey, Carolynne J

    Frontline gastroenterology

    2020  Volume 12, Issue 7, Page(s) 677–682

    Abstract: Background: Distal feeding (DF) describes the insertion of a feeding tube into a fistula or stoma to administer a liquid feed into the distal bowel. It is currently used clinically in patients who are unable to absorb enough nutrition orally. This ... ...

    Abstract Background: Distal feeding (DF) describes the insertion of a feeding tube into a fistula or stoma to administer a liquid feed into the distal bowel. It is currently used clinically in patients who are unable to absorb enough nutrition orally. This systematic review investigates DF as a therapeutic measure across a spectrum of patients with stomas and fistulae.
    Methods: A total of 2825 abstracts and 44 full-text articles were screened via OVID. Fifteen papers were included for analysis. Randomised controlled trials, cohort and observational studies investigating DF as a therapeutic measure were included.
    Results: Three feeds were used across the studies-reinfusion of effluent, infusion of prebiotic or a mixture. The studies varied the length of feeding between 24 hours and 61 days, and the mode of feeding, bolus or continuous varied.DF was demonstrated to effectively wean patients from parenteral nutrition in two papers. Two papers demonstrated a significant reduction in stoma output. Three papers demonstrated improved postoperative complication rates with distal feeding regimens, including ileus (2.85% vs 20% in unfed population, p=0.024). One paper demonstrated a reduction in postoperative stool frequency.
    Conclusions: This review was limited by study heterogeneity and the lack of trial data, and in the patient groups involved, the variability in diet and length of regimen. These studies suggest that DF can significantly reduce stoma output and improve renal and liver function; however, the mechanism is not clear. Further mechanistic work on the immunological and microbiological action of DF would be important.
    Language English
    Publishing date 2020-08-18
    Publishing country England
    Document type Systematic Review
    ZDB-ID 2521857-8
    ISSN 2041-4137
    ISSN 2041-4137
    DOI 10.1136/flgastro-2019-101359
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Medical ethics debate: access to NHS resources.

    Awatli, Ishaac / Bower, Guy / Jeyabaladevan, Sharenja / Keynejad, Roxanne / Madanire, Vongai / Michell, Alice / Thompson, Daniel / Yao, Mark

    The British journal of general practice : the journal of the Royal College of General Practitioners

    2012  Volume 62, Issue 602, Page(s) 487

    MeSH term(s) Emigration and Immigration ; Health Services Accessibility/ethics ; Humans ; Renal Dialysis/ethics ; State Medicine/ethics ; United Kingdom
    Language English
    Publishing date 2012-08-28
    Publishing country England
    Document type Journal Article
    ZDB-ID 1043148-2
    ISSN 1478-5242 ; 0035-8797 ; 0960-1643
    ISSN (online) 1478-5242
    ISSN 0035-8797 ; 0960-1643
    DOI 10.3399/bjgp12X654696
    Database MEDical Literature Analysis and Retrieval System OnLINE

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