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Artikel ; Online: Extraperitoneal pelvic packing versus angiographic embolization for hemodynamically unstable pelvic fractures: a retrospective single-center analysis.

Chu, Jisen / Xie, Changyuan / Fu, Jiaojiao / Yao, Weigen

The Journal of international medical research

2023 Band 51, Heft 10, Seite(n) 3000605231208601

Abstract: Objective: To retrospectively analyze the clinical data and treatment procedures of angiographic embolization (AE) and extraperitoneal pelvic packing (EPP) for traumatic pelvic fractures in our center for the purpose of providing recommendations on the ... ...

Abstract	Objective: To retrospectively analyze the clinical data and treatment procedures of angiographic embolization (AE) and extraperitoneal pelvic packing (EPP) for traumatic pelvic fractures in our center for the purpose of providing recommendations on the selection of treatment protocols. Methods: We analyzed 110 patients with traumatic pelvic fractures treated with AE and EPP from January 2015 to May 2023. The patients were divided into the AE group (69 men, 41 women) and the EPP group (20 men, 12 women). The primary outcomes were the mortality rate and incidence of complications. Results: The mortality rate was slightly lower in the AE than EPP group (7.3% vs. 9.4%). The overall blood transfusion volume was lower and the length of hospital stay was shorter in the AE than EPP group (7.79 ± 12.04 vs. 9.14 ± 14.21 units and 20.48 ± 11.32 vs. 22.14 ± 10.47 days). Conclusions: Both AE and EPP have good treatment effects. AE is preferred for patients in stable condition with severe hemorrhage. This study suggests that EPP should be the primary treatment and that AE should serve as a complementary treatment for critical patients.
Mesh-Begriff(e)	Male ; Humans ; Female ; Retrospective Studies ; Pelvic Bones/diagnostic imaging ; Pelvis/diagnostic imaging ; Embolization, Therapeutic/methods ; Fractures, Bone/diagnostic imaging ; Fractures, Bone/therapy
Sprache	Englisch
Erscheinungsdatum	2023-10-28
Erscheinungsland	England
Dokumenttyp	Journal Article
ZDB-ID	184023-x
ISSN	1473-2300 ; 0300-0605 ; 0142-2596
ISSN (online)	1473-2300
ISSN	0300-0605 ; 0142-2596
DOI	10.1177/03000605231208601
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Study on diagnostic value of quantitative parameters of intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) in prostate cancer.

Yao, Weigen / Liu, Jie / Zheng, Jiaju / Lu, Pengcong / Zou, Shufang / Xu, Ying

American journal of translational research

2021 Band 13, Heft 4, Seite(n) 3696–3702

Abstract: Objective: To investigate the diagnostic value of quantitative parameters of intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) in prostate cancer.: Methods: From January 2019 to June 2020, 96 patients with prostatic tumor admitted in ...

Abstract	Objective: To investigate the diagnostic value of quantitative parameters of intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) in prostate cancer. Methods: From January 2019 to June 2020, 96 patients with prostatic tumor admitted in the department of urological surgery of our hospital were selected as subjects. Magnetic resonance imaging data of 48 cases of benign prostatic hyperplasia and 48 cases of prostate cancer were retrospectively analyzed. The patients included in this study received conventional MRI and IVIM-DWI examinations. Quantitative parameters of IVIM-DWI including D value, D* value, apparent diffusion coefficient (ADC) value and f value in lesions of prostatic tumor were calculated through the double exponential model fitting algorithm. D value, D* value, ADC value and f value were compared between benign prostatic hyperplasia (BPH) group and prostate cancer group. Quantitative parameters of IVIM-DWI were also compared among patients from different Gleason scores groups. The correlation of quantitative parameters of IVIM-DWI with Gleason scores and PSA concentration was analyzed. Diagnostic efficiency of quantitative parameters of IVIM-DWI for prostate cancer was evaluated by ROC curve. Results: Compared with those in BPH group, D value, ADC value and f value in prostate cancer group were significantly lower, but D* value was obviously higher. With the Gleason score increased, D value, ADC value and f value gradually decreased, while D* value gradually increased. The diagnostic efficiency of parameters ADC and D was higher among other parameters. D value, ADC value and f value of prostate cancer were negatively correlated with Gleason score and PSA concentration, respectively (all P<0.05), while D* value was positively correlated with Gleason score and PSA concentration. Conclusions: Quantitative parameters of IVIM-DWI could be used for the diagnosis and evaluation of prostate cancer, and quantitative parameters of IVIM-DWI were associated with Gleason score and PSA concentration.
Sprache	Englisch
Erscheinungsdatum	2021-04-15
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	2471058-1
ISSN	1943-8141
ISSN	1943-8141
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: MRI and the pathology of breast invasive micropapillary carcinoma.

Han, Chun-Hong / Yao, Wei-Gen / He, Jie / Gao, Zhi-Bin / Hu, Hong-Jie

Oncology letters

2020 Band 20, Heft 3, Seite(n) 2811–2819

Abstract: Diagnosis of breast invasive micropapillary carcinoma (IMPC) before surgery is of great value for determining the optimal treatment strategy. The aim of the present study was to investigate the magnetic resonance imaging (MRI) and pathological features ... ...

Abstract	Diagnosis of breast invasive micropapillary carcinoma (IMPC) before surgery is of great value for determining the optimal treatment strategy. The aim of the present study was to investigate the magnetic resonance imaging (MRI) and pathological features of IMPC. MRI features of IMPC were characterized in relation to the patients' clinicopathological features. Clinical manifestations, mammography results and/or MRI findings of patients with IMPC were retrospectively analyzed. Parameters included morphology, plain T2-weighted imaging (T2WI) signal intensity, the apparent diffusion coefficient (ADC), the internal enhancement mode, early enhancement rates and time-intensity curve (TIC) types during dynamic enhanced scanning. A total of 10 lesions were detected by MRI in eight patients, with one case having three lesions with the mean diameter of 34.44 mm. In plain T2WI scanning, the lesions appeared inhomogeneous with a moderate or high signal intensity. When the b value was 800 sec/mm
Sprache	Englisch
Erscheinungsdatum	2020-07-09
Erscheinungsland	Greece
Dokumenttyp	Journal Article
ZDB-ID	2573196-8
ISSN	1792-1082 ; 1792-1074
ISSN (online)	1792-1082
ISSN	1792-1074
DOI	10.3892/ol.2020.11848
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Magnetic resonance imaging in categorization of ovarian epithelial cancer and survival analysis with focus on apparent diffusion coefficient value: correlation with Ki-67 expression and serum cancer antigen-125 level.

Zhang, Guofu / Yao, Weigen / Sun, Taotao / Liu, Xuefen / Zhang, Peng / Jin, Jun / Bai, Yu / Hua, Keqin / Zhang, He

Journal of ovarian research

2019 Band 12, Heft 1, Seite(n) 59

Abstract: Background: To determine whether magnetic resonance (MR) imaging features combined with apparent diffusion coefficient (ADC) values could be used as a tool for categorizing ovarian epithelial cancer (OEC) and predicting survival, as well as correlating ... ...

Abstract	Background: To determine whether magnetic resonance (MR) imaging features combined with apparent diffusion coefficient (ADC) values could be used as a tool for categorizing ovarian epithelial cancer (OEC) and predicting survival, as well as correlating with laboratory tests (serum cancer antigen 125, serum CA-125) and tumor proliferative index (Ki-67 expression). Methods and materials: MRI examination was undertaken before invasive procedures. MRI features were interpreted and recorded on the picture archive communication system (PACS). ADC measurements were manually performed on post-process workstation. Clinical characteristics were individually retrieved and recorded through the hospital information system (HIS). Cox hazard model was used to estimate the effects of both clinical and MRI features on overall survival. Results: Both clinical and MRI features differed significantly between Type I and Type II cancer groups (p < 0.05). The mean ADC value was inversely correlated with Ki-67 expression in Type I cancer (ρ = - 0.14, p < 0.05). A higher mean ADC value was more likely to suggest Type I ovarian cancer (Odds Ratio (OR) = 16.80, p < 0.01). Old age and an advanced International Federation of Gynecology and Obstetrics (FIGO) stage were significantly related to Type II ovarian cancer (OR = 0.22/0.02, p < 0.05). An advanced FIGO stage, solid components, and old age were significantly associated with poor survival (Hazard Ratio (HR) = 23.54/3.69/2.46, p < 0.05). Clear cell cancer type had a poorer survival than any other pathological subtypes of ovarian cancer (HR = 13.6, p < 0.01). Conclusions: MR imaging features combined with ADC value are helpful in categorizing OEC. ADC values can reflect tumor proliferative ability. A solid mass may predict poor prognosis for OEC patients.
Mesh-Begriff(e)	Adult ; Aged ; Biomarkers, Tumor/blood ; Biomarkers, Tumor/genetics ; CA-125 Antigen/blood ; CA-125 Antigen/metabolism ; Carcinoma, Ovarian Epithelial/blood ; Carcinoma, Ovarian Epithelial/diagnostic imaging ; Carcinoma, Ovarian Epithelial/genetics ; Carcinoma, Ovarian Epithelial/pathology ; Diffusion Magnetic Resonance Imaging ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Image Processing, Computer-Assisted ; Ki-67 Antigen/genetics ; Ki-67 Antigen/metabolism ; Middle Aged ; Ovarian Neoplasms/blood ; Ovarian Neoplasms/diagnostic imaging ; Ovarian Neoplasms/genetics ; Ovarian Neoplasms/pathology ; Prognosis ; Proportional Hazards Models ; Retrospective Studies ; Survival Analysis
Chemische Substanzen	Biomarkers, Tumor ; CA-125 Antigen ; Ki-67 Antigen
Sprache	Englisch
Erscheinungsdatum	2019-06-26
Erscheinungsland	England
Dokumenttyp	Journal Article
ZDB-ID	2455679-8
ISSN	1757-2215 ; 1757-2215
ISSN (online)	1757-2215
ISSN	1757-2215
DOI	10.1186/s13048-019-0534-0
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Optimizing prostate cancer accumulating model: combined PI-RADS v2 with prostate specific antigen and its derivative data.

Lu, Yuan-Fei / Zhang, Qian / Yao, Wei-Gen / Chen, Hai-Yan / Chen, Jie-Yu / Xu, Cong-Cong / Yu, Ri-Sheng

Cancer imaging : the official publication of the International Cancer Imaging Society

2019 Band 19, Heft 1, Seite(n) 26

Abstract: Background: To establish a new accumulating model to enhance the accuracy of prostate cancer (PCa) diagnosis by incorporating prostate-specific antigen (PSA) and its derivative data into the Prostate Imaging-Reporting and Data System version 2 (PI-RADS ... ...

Abstract	Background: To establish a new accumulating model to enhance the accuracy of prostate cancer (PCa) diagnosis by incorporating prostate-specific antigen (PSA) and its derivative data into the Prostate Imaging-Reporting and Data System version 2 (PI-RADS v2). Methods: A total of 357 patients who underwent prostate biopsy between January 2014 and December 2017 were included in this study. All patients had 3.0 T multiparametric magnetic resonance imaging (MRI) and complete laboratory examinations. PI-RADS v2 was used to assess the imaging. PSA, PSA density (PSAD), the free/total PSA ratio (f/t PSA) and the Gleason score (GS) were classified into four-tiered levels, and optimal weights were pursued on these managed levels to build a PCa accumulating model. A receiver operating characteristic curve was generated. Results: In all, 174 patients (48.7%) had benign prostatic hyperplasia, and 183 (51.3%) had PCa, among whom 149 (81.4%, 149/183) had clinically significant PCa. The established model 6 (PI-RADS v2 + level of PSAD + level of f/t PSA+ level of PSA) had a sensitivity and specificity of 81.4 and 84.5%, respectively, at the cut-off point of 11 in PCa diagnosis. Correspondingly, at the 12 cut-off point, the sensitivity and specificity were 87.7 and 83.0%, respectively, in diagnosing clinically significant PCa. The score of the new accumulating system was significantly different among the defined GS groups (p < 0.001). The mean values and 95% confidence intervals for GS 1-4 groups were 10.20 (9.63-10.40), 12.03 (11.19-12.87), 14.12 (13.60-14.64) and 15.44 (15.09-15.79). Conclusions: A new PCa accumulating model may be useful in improving the accuracy of the primary diagnosis of PCa and helpful in the clinical decision to perform a biopsy when MRI results are negative.
Mesh-Begriff(e)	Aged ; Endoscopic Ultrasound-Guided Fine Needle Aspiration ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Neoplasm Grading ; Prostate-Specific Antigen/blood ; Prostatic Hyperplasia/blood ; Prostatic Hyperplasia/diagnostic imaging ; Prostatic Hyperplasia/pathology ; Prostatic Neoplasms/blood ; Prostatic Neoplasms/diagnostic imaging ; Prostatic Neoplasms/pathology ; Sensitivity and Specificity
Chemische Substanzen	Prostate-Specific Antigen (EC 3.4.21.77)
Sprache	Englisch
Erscheinungsdatum	2019-05-23
Erscheinungsland	England
Dokumenttyp	Journal Article
ZDB-ID	2104862-9
ISSN	1470-7330 ; 1470-7330
ISSN (online)	1470-7330
ISSN	1470-7330
DOI	10.1186/s40644-019-0208-6
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Integration of quantitative diffusion kurtosis imaging and prostate specific antigen in differential diagnostic of prostate cancer.

Yao, Weigen / Zheng, Jiaju / Han, Chunhong / Lu, Pengcong / Mao, Lihua / Liu, Jie / Wang, GuiCha / Zou, Shufang / Li, Lifeng / Xu, Ying

Medicine

2021 Band 100, Heft 35, Seite(n) e27144

Abstract: Abstract: This study aimed to evaluate the diagnostic performance of diffusion kurtosis imaging (DKI) and prostate-specific antigen (PSA) biomarkers in differentiating prostate cancer (PCa) and benign prostatic hyperplasia (BPH).A total of 43 cases of ... ...

Abstract	Abstract: This study aimed to evaluate the diagnostic performance of diffusion kurtosis imaging (DKI) and prostate-specific antigen (PSA) biomarkers in differentiating prostate cancer (PCa) and benign prostatic hyperplasia (BPH).A total of 43 cases of prostate diseases verified by pathology were enrolled in the present study. These cases were assigned to the BPH group (n = 20, 68.85±10.81 years old) and PCa group (n = 23, 74.13 ± 7.37 years old). All patients underwent routine prostate magnetic resonance imaging and DKI examinations, and the mean diffusivity (MD), mean kurtosis (MK), and fractional anisotropy (FA) values were calculated. Three serum indicators (PSA, free PSA [fPSA], and f/t PSA) were collected. We used univariate logistic regression to analyze the above quantitative parameters between the 2 groups, and the independent factors were further incorporated into the multivariate logistic regression model. The area under the receiver operating characteristic curve (AUC) was used to evaluate the diagnostic efficacy of the single indicator and combined model.The difference in PSA, f/t PSA, MK, and FA between PCa and BPH was statistically significant (P < .05). The AUC for the combined model (f/t PSA, MK, and FA) of 0.972 (95% confidence interval [CI]: 0.928, 1.000) was higher than the AUC of 0.902 (95% CI: 0.801, 1.000) for f/t PSA, 0.833 (95% CI: 0.707, 0.958) for MK, and 0.807 (95% CI: 0.679, 0.934) for FA.The MK and FA values for DKI and f/t PSA effectively identify PCa and BPH, compared to the PSA indicators. Combining DKI and PSA derivatives can further improve the diagnosis efficiency and might help in the clinical setting.
Mesh-Begriff(e)	Aged ; Aged, 80 and over ; Diagnosis, Differential ; Humans ; Magnetic Resonance Imaging/methods ; Male ; Middle Aged ; Prostate-Specific Antigen/blood ; Prostatic Hyperplasia/blood ; Prostatic Hyperplasia/diagnostic imaging ; Prostatic Neoplasms/blood ; Prostatic Neoplasms/diagnostic imaging ; Retrospective Studies
Chemische Substanzen	Prostate-Specific Antigen (EC 3.4.21.77)
Sprache	Englisch
Erscheinungsdatum	2021-09-02
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000027144
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Massive localized malignant pleural mesothelioma (LMPM): manifestations on computed tomography in 6 cases.

Yao, Weigen / Yang, Hanqing / Huang, Guolai / Yan, Yang / Wang, Honglin / Sun, Dongfang

International journal of clinical and experimental medicine

2015 Band 8, Heft 10, Seite(n) 18367–18374

Abstract: Objective: Our study analyzed the clinical symptoms and computed tomography (CT) manifestations of massive localized malignant pleural mesothelioma (LMPM) patients to improve the knowledge and diagnosis of this disease.: Methods: Our study collected ... ...

Abstract	Objective: Our study analyzed the clinical symptoms and computed tomography (CT) manifestations of massive localized malignant pleural mesothelioma (LMPM) patients to improve the knowledge and diagnosis of this disease. Methods: Our study collected 6 massive LMPM patients pathologically confirmed by CT in the department of Radiology of the People's Hospital of Yuyao, Zhejiang Province, from January, 2007 to June, 2013; data of patients were also collected. The clinical symptoms, clinicopathological characteristics, CT manifestations, treatments and prognosis of enrolled patients were analyzed. Results: Our study enrolled 6 LMPM patients (2 males; 4 females) classified to epitheliated type (n = 4) and sarcomatous type (n = 2) with mean age of 62.7 ± 7.4, and 5 of them had a history of asbestos exposure. CT manifestations revealed that large soft-tissue mass close to pleura, which was smooth and lobulated, was discovered in all patients with maximum diameter of 10~15 cm and mean diameter of 13.67 ± 1.15 cm; The mean value of CT was 36.29 ± 2.62 HU; after enhancement, the mean value was increased to 76.36 ± 7.73 HU; patients showed zones of small patchy necrosis and large patchy necrosis. The following presentations were founded: enlargement of tumor vessel which showed arborization (2 patients), mass wrap around the descending aorta in left lower chest (1 patient), strips of fat density in mediastinum superior (1 patient), pleural tail sign (3 patients). Among 6 patients, pleural effusion (n = 4), mediastinal lymph node enlargement (n = 3), invasion and destruction of local ribs (n = 2). Median survival time of patients were 20 months (2 cases conducted operation), 24 (2 cases chose combined radiotherapy and chemotherapy) and less than 6 months (2 cases underwent chemotherapy). Conclusion: To sum up, CT showed important diagnostic values on massive LMPM patients; patients with a history of asbestos exposure, large soft-tissue mass of pleura with an abundant blood supply and wrap around large vessels might increase the risk of massive LMPM.
Sprache	Englisch
Erscheinungsdatum	2015-10-15
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	2418305-2
ISSN	1940-5901
ISSN	1940-5901
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Magnetic resonance imaging radiomics in categorizing ovarian masses and predicting clinical outcome: a preliminary study.

Zhang, He / Mao, Yunfei / Chen, Xiaojun / Wu, Guoqing / Liu, Xuefen / Zhang, Peng / Bai, Yu / Lu, Pengcong / Yao, Weigen / Wang, Yuanyuan / Yu, Jinhua / Zhang, Guofu

European radiology

2019 Band 29, Heft 7, Seite(n) 3358–3371

Abstract: Purpose: To evaluate the ability of MRI radiomics to categorize ovarian masses and to determine the association between MRI radiomics and survival among ovarian epithelial cancer (OEC) patients.: Method: A total of 286 patients with pathologically ... ...

Abstract	Purpose: To evaluate the ability of MRI radiomics to categorize ovarian masses and to determine the association between MRI radiomics and survival among ovarian epithelial cancer (OEC) patients. Method: A total of 286 patients with pathologically proven adnexal tumor were retrospectively included in this study. We evaluated diagnostic performance of the signatures derived from MRI radiomics in differentiating (1) between benign adnexal tumors and malignancies and (2) between type I and type II OEC. The least absolute shrinkage and selection operator method was used for radiomics feature selection. Risk scores were calculated from the Lasso model and were used for survival analysis. Result: For the classification between benign and malignant masses, the MRI radiomics model achieved a high accuracy of 0.90 in the leave-one-out (LOO) cross-validation cohort and an accuracy of 0.87 in the independent validation cohort. For the classification between type I and type II subtypes, our method made a satisfactory classification in the LOO cross-validation cohort (accuracy = 0.93) and in the independent validation cohort (accuracy = 0.84). Low-high-high short-run high gray-level emphasis and low-low-high variance from coronal T2-weighted imaging (T2WI) and eccentricity from axial T1-weighted imaging (T1WI) images had the best performance in two classification tasks. The patients with higher risk scores were more likely to have poor prognosis (hazard ratio = 4.1694, p = 0.001). Conclusion: Our results suggest radiomics features extracted from MRI are highly correlated with OEC classification and prognosis of patients. MRI radiomics can provide survival estimations with high accuracy. Key points: • The MRI radiomics model could achieve a higher accuracy in discriminating benign ovarian diseases from malignancies. • Low-high-high short-run high gray-level emphasis, low-low-high variance from coronal T2WI, and eccentricity from axial T1WI had the best performance outcomes in various classification tasks. • The ovarian cancer patients with high-risk scores had poor prognosis.
Mesh-Begriff(e)	Adult ; Aged ; Cohort Studies ; Diagnosis, Differential ; Female ; Follow-Up Studies ; Humans ; Image Interpretation, Computer-Assisted/methods ; Kaplan-Meier Estimate ; Magnetic Resonance Imaging/methods ; Middle Aged ; Ovarian Neoplasms/diagnostic imaging ; Prognosis ; ROC Curve ; Reproducibility of Results ; Retrospective Studies
Sprache	Englisch
Erscheinungsdatum	2019-04-08
Erscheinungsland	Germany
Dokumenttyp	Evaluation Study ; Journal Article
ZDB-ID	1085366-2
ISSN	1432-1084 ; 0938-7994 ; 1613-3749
ISSN (online)	1432-1084
ISSN	0938-7994 ; 1613-3749
DOI	10.1007/s00330-019-06124-9
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: An Illustrated Guide to the Imaging Evolution of COVID in Non-Epidemic Areas of Southeast China.

Frontiers in molecular biosciences

2021 Band 8, Seite(n) 648180

Abstract: Purpose: ...

Abstract	Purpose:
Sprache	Englisch
Erscheinungsdatum	2021-05-28
Erscheinungsland	Switzerland
Dokumenttyp	Journal Article
ZDB-ID	2814330-9
ISSN	2296-889X
ISSN	2296-889X
DOI	10.3389/fmolb.2021.648180
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Temporal changes of COVID-19 pneumonia by mass evaluation using CT: a retrospective multi-center study.

Annals of translational medicine

2020 Band 8, Heft 15, Seite(n) 935

Abstract: Background: Coronavirus disease 2019 (COVID-19) has widely spread worldwide and caused a pandemic. Chest CT has been found to play an important role in the diagnosis and management of COVID-19. However, quantitatively assessing temporal changes of COVID- ...

Abstract	Background: Coronavirus disease 2019 (COVID-19) has widely spread worldwide and caused a pandemic. Chest CT has been found to play an important role in the diagnosis and management of COVID-19. However, quantitatively assessing temporal changes of COVID-19 pneumonia over time using CT has still not been fully elucidated. The purpose of this study was to perform a longitudinal study to quantitatively assess temporal changes of COVID-19 pneumonia. Methods: This retrospective and multi-center study included patients with laboratory-confirmed COVID-19 infection from 16 hospitals between January 19 and March 27, 2020. Mass was used as an approach to quantitatively measure dynamic changes of pulmonary involvement in patients with COVID-19. Artificial intelligence (AI) was employed as image segmentation and analysis tool for calculating the mass of pulmonary involvement. Results: A total of 581 confirmed patients with 1,309 chest CT examinations were included in this study. The median age was 46 years (IQR, 35-55; range, 4-87 years), and 311 (53.5%) patients were male. The mass of pulmonary involvement peaked on day 10 after the onset of initial symptoms. Furthermore, the mass of pulmonary involvement of older patients (>45 years) was significantly severer (P<0.001) and peaked later (day 11 Conclusions: Pulmonary involvement peaked on day 10 after the onset of initial symptoms in patients with COVID-19. Further, pulmonary involvement of older patients was severer and peaked later than that of younger patients. These findings suggest that AI-based quantitative mass evaluation of COVID-19 pneumonia hold great potential for monitoring the disease progression.
Schlagwörter	covid19
Sprache	Englisch
Erscheinungsdatum	2020-09-17
Erscheinungsland	China
Dokumenttyp	Journal Article
ZDB-ID	2893931-1
ISSN	2305-5847 ; 2305-5839
ISSN (online)	2305-5847
ISSN	2305-5839
DOI	10.21037/atm-20-4004
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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