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Article ; Online: 3D Printing Silk Fibroin/Polyacrylamide Triple-Network Composite Hydrogels with Stretchability, Conductivity, and Strain-Sensing Ability as Bionic Electronic Skins.

Niu, Qianqian / Huang, Li / Fan, Suna / Yao, Xiang / Zhang, Yaopeng

ACS biomaterials science & engineering

2024

Abstract: Electronic skins have received increasing attention due to their great application potential in wearable electronics. Meanwhile, tremendous efforts are still needed for the fabrication of multifunctional composite hydrogels with complex structures for ... ...

Abstract	Electronic skins have received increasing attention due to their great application potential in wearable electronics. Meanwhile, tremendous efforts are still needed for the fabrication of multifunctional composite hydrogels with complex structures for electronic skins via simple methods. In this work, a novel three-dimensional (3D) printing composite hydrogel with stretchability, conductivity, and strain-sensing ability is produced using a one-step photocuring method to achieve a dual-signal response of the electronic skin. The composite hydrogel exhibits a triple-network structure composed of silk microfibers (SMF), regenerated silk fibroin (RSF), and polyacrylamide (PAM). The establishment of triple networks is based on the electrostatic interaction between SMF and RSF, as well as the chemically cross-linked RSF and PAM. Thanks to its specific structure and components, the composite hydrogel possesses enhanced mechanical properties (elastic modulus of 140 kPa, compressive stress of 21 MPa, and compression modulus of 600 kPa) and 3D printability while retaining stretchability and flexibility. The interaction between negatively charged SMF and cations in phosphate-buffered saline endows the composite hydrogel with good conductivity and strain-sensing ability after immersion in a low-concentration (10 mM) salt solution. Moreover, the 3D printing composite hydrogel scaffold successfully realizes real-time monitoring. Therefore, the proposed hydrogel-based ionic sensor is promising for skin tissue engineering, real-time monitoring, soft robotics, and human-machine interfaces.
Language	English
Publishing date	2024-04-25
Publishing country	United States
Document type	Journal Article
ISSN	2373-9878
ISSN (online)	2373-9878
DOI	10.1021/acsbiomaterials.4c00201
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Article ; Online: Coloration differences in three Camellia reticulata Lindl. cultivars: 'Tongzimian', 'Shizitou' and 'Damanao'.

Qu, Yan / Ou, Zhi / Yong, Qing Qing / Yao, Xiang / Luo, Jun

BMC plant biology

2024 Volume 24, Issue 1, Page(s) 18

Abstract: Camellia reticulata Lindl., also known as Yunnan Camellia, is an important ornamental plant in China, especially for its large and stunning flowers. A comprehensive understanding of their coloration mechanisms can aid breeders in developing new cultivars ...

Abstract	Camellia reticulata Lindl., also known as Yunnan Camellia, is an important ornamental plant in China, especially for its large and stunning flowers. A comprehensive understanding of their coloration mechanisms can aid breeders in developing new cultivars and improving their ornamental value; however, it is still unclear in Yunnan Camellia, especially in mixed-color flowers. In this study, we conducted metabolic and transcriptomic comparison analyses to investigate the coloration differences in three Yunnan Camellia cultivars: C. reticulata 'Shizitou' (SZT), C. reticulata 'Damanao' (MN), and C. reticulata 'Tongzimian' (TZM). Our results revealed that the initial flowering stage may play a critical role in the color change of MN. Metabolome analysis demonstrated that cyanidin was the primary anthocyanin in SZT and MN's red region, while its content was low in TZM and MN's white region. According to the transcriptome analysis, the anthocyanins biosynthesis pathway was reconstructed in Yunnan Camellia, and the low expression of CHS was detected in TZM and MN's white region, while ANR maintained a high expression level, which may lead to the low content of cyanidin in them. Transcription factors MYBs, bHLH, and bZIP may play a key role in regulating anthocyanin-structural genes. The co-expression analysis showed that the meristem tissue may play a crucial role in the formation of the mixed white-red color in MN. Our study enriched the genetic basis of flower coloration differences in Yunnan Camellia which will be a valuable genomic resource to understanding the biology of coloration formation and for breeding the Camellia cultivars.
MeSH term(s)	Camellia/genetics ; Camellia/metabolism ; Anthocyanins/metabolism ; China ; Plant Breeding ; Gene Expression Profiling ; Flowers/metabolism ; Gene Expression Regulation, Plant ; Transcriptome ; Pigmentation/genetics
Chemical Substances	Anthocyanins
Language	English
Publishing date	2024-01-02
Publishing country	England
Document type	Journal Article
ZDB-ID	2059868-3
ISSN	1471-2229 ; 1471-2229
ISSN (online)	1471-2229
ISSN	1471-2229
DOI	10.1186/s12870-023-04655-4
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Article ; Online: Cellular and molecular mechanisms of highly active mesenchymal stem cells in the treatment of senescence of rhesus monkey ovary.

Wang, Kai / Yao, Xiang / Lin, Shu-Qian / Zhu, Xiang-Qing / Pan, Xing-Hua / Ruan, Guang-Ping

Stem cell research & therapy

2024 Volume 15, Issue 1, Page(s) 14

Abstract: Background: Recent studies have shown that umbilical cord mesenchymal stem cells have an anti-aging effect in ovaries, but the cellular and molecular mechanisms of HA-MSC ovarian anti-aging remain to be studied. Therefore, we conducted a 10X Genomics ... ...

Abstract	Background: Recent studies have shown that umbilical cord mesenchymal stem cells have an anti-aging effect in ovaries, but the cellular and molecular mechanisms of HA-MSC ovarian anti-aging remain to be studied. Therefore, we conducted a 10X Genomics single-nucleus transcriptome sequencing experiment on the ovaries of macaque monkeys after HA-MSC treatment. Methods: The results of cell subgroup classification were visualized by 10X Genomics single nuclear transcriptome sequencing. The aging model of hGCs was established, and the migration ability of the cells was determined after coculture of HA-MSCs and aging hGCs. The genes screened by single nuclear transcriptional sequencing were verified in vitro by qPCR. Results: Compared with the aging model group, the number of cell receptor pairs in each subgroup of the HA-MSC-treated group increased overall. Treatment with 200 μmol/L H Conclusions: HA-MSC therapy can improve the tissue structure and secretion function of the ovary through multiple cellular and molecular mechanisms to resist ovarian aging. In vitro validation experiments further supported the results of single-cell sequencing, which provides evidence supporting a new option for stem cell treatment of ovarian senescence.
MeSH term(s)	Female ; Animals ; Macaca mulatta ; Ovary ; Hydrogen Peroxide ; Aging ; Mesenchymal Stem Cells
Chemical Substances	Hydrogen Peroxide (BBX060AN9V)
Language	English
Publishing date	2024-01-08
Publishing country	England
Document type	Journal Article
ZDB-ID	2548671-8
ISSN	1757-6512 ; 1757-6512
ISSN (online)	1757-6512
ISSN	1757-6512
DOI	10.1186/s13287-023-03631-x
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Article: A nomogram for predicting the necessity of tracheostomy after severe acute brain injury in patients within the neurosurgery intensive care unit: A retrospective cohort study.

Gao, Liqin / Chang, Yafen / Lu, Siyuan / Liu, Xiyang / Yao, Xiang / Zhang, Wei / Sun, Eryi

Heliyon

2024 Volume 10, Issue 6, Page(s) e27416

Abstract: Objective: This retrospective study was aimed to develop a predictive model for assessing the necessity of tracheostomy (TT) in patients admitted to the neurosurgery intensive care unit (NSICU).: Method: We analyzed data from 1626 NSICU patients with ...

Abstract	Objective: This retrospective study was aimed to develop a predictive model for assessing the necessity of tracheostomy (TT) in patients admitted to the neurosurgery intensive care unit (NSICU). Method: We analyzed data from 1626 NSICU patients with severe acute brain injury (SABI) who were admitted to the Department of NSICU at the Affiliated People's Hospital of Jiangsu University between January 2021 and December 2022. Data of the patients were retrospectively obtained from the clinical research data platform. The patients were randomly divided into training (70%) and testing (30%) cohorts. The least absolute shrinkage and selection operator (LASSO) regression identified the optimal predictive features. A multivariate logistic regression model was then constructed and represented by a nomogram. The efficacy of the model was evaluated based on discrimination, calibration, and clinical utility. Results: The model highlighted six predictive variables, including the duration of NSICU stay, neurosurgery, orotracheal intubation time, Glasgow Coma Scale (GCS) score, systolic pressure, and respiration rate. Receiver operating characteristic (ROC) analysis of the nomogram yielded area under the curve (AUC) values of 0.854 (95% confidence interval [CI]: 0.822-0.886) for the training cohort and 0.865 (95% CI: 0.817-0.913) for the testing cohort, suggesting commendable differential performance. The predictions closely aligned with actual observations in both cohorts. Decision curve analysis demonstrated that the numerical model offered a favorable net clinical benefit. Conclusion: We developed a novel predictive model to identify risk factors for TT in SABI patients within the NSICU. This model holds the potential to assist clinicians in making timely surgical decisions concerning TT.
Language	English
Publishing date	2024-03-09
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2024.e27416
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Article ; Online: Newcomers building social capital by proactive networking: A signaling perspective.

Boulamatsi, Artemis / Liu, Songqi / Zhou, Le / Yin, Jingfeng / Yao, Xiang / Guo, Rui

The Journal of applied psychology

2024

Abstract: Social networks can aid newcomers' learning and adjustment and facilitate their performance. However, knowledge about how newcomers build their social networks from the ground up is limited. Extending the socialization literature, we propose a model ... ...

Abstract	Social networks can aid newcomers' learning and adjustment and facilitate their performance. However, knowledge about how newcomers build their social networks from the ground up is limited. Extending the socialization literature, we propose a model delineating newcomer proactive networking as the driver of advice ties with peer newcomers, which in turn influence newcomer reputation among higher status organizational insiders. Drawing on signaling theory, we propose that future-oriented newcomers are more likely to engage in proactive networking behaviors, a form of signaling that could help those newcomers build a larger number of peer advice ties. Such initial success may then transmit newcomers' signals to the managerial ranks, affording them a better reputation among managers. In addition, signaling theory suggests that the centrality of a newcomer's immediate supervisor in the managerial advice network can amplify the effect of the newcomer's own signaling actions (i.e., proactive networking behaviors) on their relationships with peers. We tested our hypotheses in two field survey studies. Study 1 found that newcomers higher in future orientation engaged in more proactive networking. Proactive networking helped newcomers form more peer advice ties, which were, in turn, positively related to their reputation among managers. Study 2 found that the supervisor's centrality in the managerial advice network moderated the relationship between newcomer proactive networking and peer advice ties. We discuss the implications of our findings for the newcomer adjustment and signaling theory literatures as well as for socialization practices. (PsycInfo Database Record (c) 2024 APA, all rights reserved).
Language	English
Publishing date	2024-04-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	219157-x
ISSN	1939-1854 ; 0021-9010
ISSN (online)	1939-1854
ISSN	0021-9010
DOI	10.1037/apl0001187
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Article ; Online: Seasonal Variation and Positional Differences in Anthropometry, Strength, and Power Characteristics in English Premiership Women's Rugby Union Players.

Yao, Xiang / Austerberry, Alex / Bishop, Chris / Wilson, Laura / Chiang, Chien-Ying / Turner, Anthony

Journal of strength and conditioning research

2024 Volume 38, Issue 5, Page(s) 924–931

Abstract: Abstract: Yao, X, Austerberry, A, Bishop, C, Wilson, L, Chiang, C-Y, and Turner, A. Seasonal variation and positional differences in anthropometry, strength, and power characteristics in English premiership women's rugby union players. J Strength Cond ... ...

Abstract	Abstract: Yao, X, Austerberry, A, Bishop, C, Wilson, L, Chiang, C-Y, and Turner, A. Seasonal variation and positional differences in anthropometry, strength, and power characteristics in English premiership women's rugby union players. J Strength Cond Res 38(5): 924-931, 2024-Women's rugby is a collision sport that relies heavily on body composition and physical characteristics of strength and power to achieve competitive success. Furthermore, the seasonal nature presents a variety of physical challenges that can cause fluctuations in a player's physical development. Therefore, the purpose of this study was to determine the differences in anthropometry, strength, and power characteristics between forwards and backs in women's rugby union athletes in England and to identify changes throughout a season. Forty-seven players were recruited from the English premiership women's rugby during the 2020-2021 season. Players were split into forwards and backs and underwent body composition testing by dual-energy X-ray absorptiometry and strength and power tests (countermovement jump, drop jump [DJ], and isometric midthigh pull) on 3 separate occasions (preseason, midseason, postseason). Overall, forwards had significantly ( p < 0.01) higher body mass, fat mass, lean mass [LM], bone mineral content, and take off momentum, and backs had significantly higher ( p < 0.01, d > 0.5) jump height, reactive strength, and shorter DJ contact time. When observing seasonal changes, there were statistically significant differences ( p < 0.01) or moderate-to-large practical differences ( d > 0.5) in LM, reactive strength index modified, time to take-off, and DJ flight time [FT] among forwards when comparing 3 testing time frames. For backs, statistically significant differences ( p < 0.01) or moderate-to-large practical differences ( d > 0.5) were reported in LM and DJ FT throughout the season. In conclusion, the strength and power testing and characteristics shown in this study could support coaches and junior women's rugby athletes to have a basic understanding of English premiership physical standards.
MeSH term(s)	Humans ; Female ; Muscle Strength/physiology ; Seasons ; Young Adult ; Anthropometry ; Body Composition/physiology ; England ; Adult ; Football/physiology ; Athletic Performance/physiology ; Absorptiometry, Photon ; Athletes ; Rugby/physiology
Language	English
Publishing date	2024-04-11
Publishing country	United States
Document type	Journal Article
ZDB-ID	1156349-7
ISSN	1533-4287 ; 1064-8011
ISSN (online)	1533-4287
ISSN	1064-8011
DOI	10.1519/JSC.0000000000004736
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Article: When Does Safety Climate Help? A Multilevel Study of COVID-19 Risky Decision Making and Safety Performance in the Context of Business Reopening.

Wang, Yi / He, Yimin / Sheng, Zitong / Yao, Xiang

Journal of business and psychology

2022 Volume 37, Issue 6, Page(s) 1313–1327

Abstract: Businesses are gradually reopening as lockdown measures for the coronavirus disease 2019 (COVID-19) pandemic are being relieved in many places across the globe. It is challenging but imperative for businesses to manage the risk of infection in the ... ...

Abstract	Businesses are gradually reopening as lockdown measures for the coronavirus disease 2019 (COVID-19) pandemic are being relieved in many places across the globe. It is challenging but imperative for businesses to manage the risk of infection in the workplace and reopen safely. Drawing on risky decision-making theory and the job demands-resource model of workplace safety, we examined the influences of employees' COVID-19 risk perception on their safety performance at work. On the one hand, COVID-19 risk perception motivates employees to perform safely; on the other hand, COVID-19 risk perception could also undermine safety performance through triggering anxiety. In an effort to find ways that alleviate the negative implications of risk perception, we also tested a cross-level interaction model where the risk perception-anxiety relation is weakened with a favorable team safety climate as well as low abusive supervision. Our data were collected from car dealership employees located in China in March 2020, when businesses just started to reopen in locations where these data were collected. Results showed that COVID-19 risk perception was positively related to anxiety, which in turn undermined safety performance. This negative effect canceled out the direct positive effects of COVID-19 risk perception on safety performance. In addition, cross-level interaction results showed that the buffering effect of team safety climate on the risk perception-anxiety relation was diminished with an abusive supervisor. Our findings provide valuable and timely implications on risk management and workplace safety during a public health crisis such as the COVID-19 pandemic.
Language	English
Publishing date	2022-03-15
Publishing country	United States
Document type	Journal Article
ZDB-ID	2016738-6
ISSN	1573-353X ; 0889-3268
ISSN (online)	1573-353X
ISSN	0889-3268
DOI	10.1007/s10869-022-09805-3
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Article: Association of coronary artery calcification with SYNTAX scores and GRACE.

Yao, Xiang / Xing, Bo / Liu, Ting

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences

2022 Volume 45, Issue 11, Page(s) 1326–1335

Abstract: Objectives: To investigate the relationship among coronary artery calcification score (CACS), the number of calcification vessels, SYNTAX score and GRACE score in patients with coronary atherosclerotic heart disease (CHD).: Methods: The CACS, ... ...

Title translation	冠状动脉钙化与SYNTAX评分和GRACE评分的相关性.
Abstract	Objectives: To investigate the relationship among coronary artery calcification score (CACS), the number of calcification vessels, SYNTAX score and GRACE score in patients with coronary atherosclerotic heart disease (CHD). Methods: The CACS, calcification vessel number, SYNTAX score, and GRACE score were collected or calculated from 214 CHD patients admitted in Haikou People's Hospital from January 2014 to April 2019. Patients were assigned into several groups according to the CACS and calcification vessel number, and then to compare the differences in SYNTAX and GRACE scores between groups. Spearman correlation coefficient was used to analyze the correlation between CACS or calcification vessel number and SYTAX score or GRACE score. Regression of binary logistic was used to analyze independent risk factors for coronary calcification. The diagnostic values of the CACS and calcification vessel number for predicting CHD, and SYNTAX score and GRACE score high-risk group were evaluated by the receiver operator characteristic (ROC) curve. Results: Spearman correlation analysis showed that CACS was positively correlated with SYTAX score ( Conclusions: In patients with suspected CHD, CACS and calcification vessel number can predict the severity of CHD and the risk of future cardiovascular events. Measuring the CACS and the number of calcification vessels before coronary angiography has certain clinical significance for predicting the severity of coronary lesion and formulating the treatment plan.
Language	Chinese
Publishing date	2022-06-26
Publishing country	China
Document type	Journal Article
ZDB-ID	2168533-2
ISSN	1672-7347
ISSN	1672-7347
DOI	10.11817/j.issn.1672-7347.2020.200043
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Article ; Online: Effects of Microstripe Geometry on Guided Cell Migration.

Yao, Xiang / Ding, Jiandong

ACS applied materials & interfaces

2020 Volume 12, Issue 25, Page(s) 27971–27983

Abstract: Cell migration on material surfaces is a fundament issue in the fields of biomaterials, cell biology, tissue engineering, regenerative medicine, etc. Herein, we aim to guide cell migration by flat microstripes with significant contrast of cell adhesion ... ...

Abstract	Cell migration on material surfaces is a fundament issue in the fields of biomaterials, cell biology, tissue engineering, regenerative medicine, etc. Herein, we aim to guide cell migration by flat microstripes with significant contrast of cell adhesion and varied geometric features of the adhesive stripes. To this end, we designed and fabricated cell-adhesive arginine-glycine-aspartate (RGD) microstripes on the nonfouling poly(ethylene glycol) (PEG) background and examined the microstripe-guided adhesion and migration of a few cell types. The migration of cell clusters adhering on the RGD regions was found to be significantly affected by the widths and arc radiuses of the guided microstripes. The cells migrated fastest on the straight microstripes with width of about 20 μm, which we defined as single file confined migration (SFCM). We also checked the possible left-right asymmetric bias of cell migration guided by combinatory microstripes with alternative wavy and quasi-straight stripes under a given width, and found that the velocity of CCW (counter clockwise) migration was higher than that of CW (clockwise) migration for primary rat mesenchymal stem cells (rMSCs), whereas no left-right asymmetric bias was observed for NIH3T3 (mouse embryonic fibroblast cell line) and Hela (human cervix epithelial carcinoma cell line) cells. Comparison of migration of cells on the nanotopological stripe and smooth surfaces further confirmed the importance of cell orientation coherence for guided cell migration and strengthened the superiority of SFCM.
MeSH term(s)	Animals ; Biocompatible Materials/chemistry ; Cell Adhesion/physiology ; Cell Differentiation/physiology ; Cell Movement/physiology ; HeLa Cells ; Humans ; Mesenchymal Stem Cells/cytology ; Mice ; NIH 3T3 Cells ; Oligopeptides/chemistry ; Polyethylene Glycols/chemistry ; Rats
Chemical Substances	Biocompatible Materials ; Oligopeptides ; Polyethylene Glycols (3WJQ0SDW1A) ; arginyl-glycyl-aspartic acid (78VO7F77PN)
Language	English
Publishing date	2020-06-12
Publishing country	United States
Document type	Journal Article
ISSN	1944-8252
ISSN (online)	1944-8252
DOI	10.1021/acsami.0c05024
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Article ; Online: Quantifying vegetation change and driving mechanism analysis in Sichuan from 2000 to 2020

Lina Ning / Wenfu Peng / Yanan Yu / JiaYao Xiang / Yong Wang

Frontiers in Environmental Science, Vol

2023 Volume 11

Abstract: Vegetation cover is a crucial indicator of biodiversity and ecological processes, but there are still uncertainties about the factors driving changes in vegetation. In this study, we conducted a comprehensive analysis of vegetation cover changes in ... ...

Abstract	Vegetation cover is a crucial indicator of biodiversity and ecological processes, but there are still uncertainties about the factors driving changes in vegetation. In this study, we conducted a comprehensive analysis of vegetation cover changes in Sichuan Province from 2000 to 2020 using Formation Vegetation Cover (FVC) derived from MODIS13Q1 data. Our results revealed a consistent increase in vegetation FVC, rising from 0.506 to 0.624 over the 21-year period, with an annual growth rate of 0.0028. The turning point in this growth occurred in 2006. Of significance, the expansion of vegetation covered a substantial portion, accounting for 84.76%, while the decrease constituted 13%. Elevation proved to be an effective explanatory factor, with a coefficient of 0.417, indicating its role in explaining vegetation cover changes. It is important to note that FVC trends and averages exhibited distinct patterns concerning elevation, land use, population density, topography, and soil type, while their correlation with meteorological factors was relatively weak. Concurrently, the increase in construction and urban development had a negative impact on vegetation cover.
Keywords	GeoDetectors ; human activities ; sichuan province ; spatial and temporal dynamics ; vegetation cover ; Environmental sciences ; GE1-350
Subject code	910
Language	English
Publishing date	2023-10-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
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