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Artikel: Functional properties and adipogenesis inhibitory activity of protein hydrolysates from quinoa (Chenopodium quinoa Willd.)

Yao, Yang

Food Science & Nutrition, 7(6):2103-2112

2019

Abstract: The functional properties and adipogenesis inhibitory activity of quinoa protein hydrolysates, prepared using papain, pepsin, and pancreatin for 0, 30, 60, 90, and 120 min, were studied. For these three kinds of proteases, the solubility of the ... ...

Abstract	The functional properties and adipogenesis inhibitory activity of quinoa protein hydrolysates, prepared using papain, pepsin, and pancreatin for 0, 30, 60, 90, and 120 min, were studied. For these three kinds of proteases, the solubility of the hydrolysates significantly increased with the increasing DH in pH range of 3–8, while the EAI and ESI of these hydrolysates significantly decreased during hydrolysis. The anti‐inflammatory activity of these protein hydrolysates was measured. All of these protein hydrolysates showed high anti‐inflammatory activity. However, there was no significant difference in anti‐inflammatory activity between protein hydrolysates and total protein from quinoa. These protein hydrolysates also inhibited lipid accumulation during differentiation within the range of concentrations of 0–1,600 μg/ml, which exerted no cytotoxicity toward 3T3‐L1 cells. The protein hydrolysates from quinoa prepared using pepsin for 120 min (PEP‐120) had the highest activity with an IC50 value of 786.58 μg/ml. Moreover, LC‐MS/MS analysis of PEP‐120 showed that five main bioactive peptides, which have been demonstrated to have ACE inhibitor, antioxidant, and antithrombotic activities, were present in PEP‐120. In addition, gene expression and Western blot analysis revealed that PEP‐120 suppressed the 3T3‐L1 cell differentiation through the peroxisome proliferator‐activated receptor γ (PPARγ) pathway.
Schlagwörter	anti‐inflammation ; adipogenesis inhibitory activity ; functional properties ; quinoa protein hydrolysates
Sprache	Englisch
Dokumenttyp	Artikel
Datenquelle	Fachrepositorium Lebenswissenschaften

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Artikel ; Online: Critical care response during the COVID-19 pandemic

Wei-Chih Chen / Kuang-Yao Yang

Journal of the Formosan Medical Association, Vol 123, Iss , Pp S55-S

2024 Band 60

Abstract: Since the coronavirus disease 2019 (COVID-19) pandemic, millions of people worldwide have passed away due to critical illness. Intensive care for severe COVID-19 infection remains one of the most important ways to save patients’ lives. In Taiwan, the ... ...

Abstract	Since the coronavirus disease 2019 (COVID-19) pandemic, millions of people worldwide have passed away due to critical illness. Intensive care for severe COVID-19 infection remains one of the most important ways to save patients’ lives. In Taiwan, the government-led critical care model and COVID-19 clinical rounds, grand rounds, and chief rounds by experts; critical care guidelines established by the Taiwan Centers for Disease Control and major professional societies; consensus and management recommendations among medical institutes; and research works in the field of critical care constitute the concrete basis of intensive care. This review article briefly summarizes the current achievements of critical care for COVID-19 in Taiwan and recommendations on future directions.
Schlagwörter	Coronavirus disease 2019 (COVID-19) ; Critical care ; Intensive care unit (ICU) ; Taiwan ; Medicine (General) ; R5-920
Sprache	Englisch
Erscheinungsdatum	2024-01-01T00:00:00Z
Verlag	Elsevier
Dokumenttyp	Artikel ; Online
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Artikel ; Online: Assessing the effects of environmental factors on filtration rate of golden mussel (Limnoperna fortunei)

Jiahao Zhang / Mengzhen Xu / Yao Yang

Ecological Indicators, Vol 158, Iss , Pp 111544- (2024)

2024

Abstract: Filtration rate is a crucial characteristic for bivalves that engage in filter feeding, and is subject to regulation in response to various environmental factors. Golden mussel, Limnoperna fortunei, known as intensively invasive species in South America ... ...

Abstract	Filtration rate is a crucial characteristic for bivalves that engage in filter feeding, and is subject to regulation in response to various environmental factors. Golden mussel, Limnoperna fortunei, known as intensively invasive species in South America and many Asian regions, has been observed to exhibit a wide range of filtration rate, resulting in challenges in hydraulic modeling and impact assessment. In this study, we performed a series of experiments and developed a mussel pump model to assess the filtration rate of golden mussels with different shell lengths and to investigate the impact of environmental factors that influence the filtration rate, i.e., food type, water temperature, and flow condition. We found that filtration rates increased with shell length, while filtration rates per unit weight decreased with shell length. Additionally, we observed that filtration rates were comparable when the mussels were fed with food that share similar/identical cellular properties, e.g., Saccharomyces cerevisiae and Chlorella pyrenoidosa. The temperature's effect on filtration rates followed a skewed unimodal pattern, with an optimal temperature near 20 ℃. Interestingly, the experiments also showed that the golden mussel can filter at low temperatures (2 ℃), indicating its capacity for overwinter survival in cold regions. Moreover, the golden mussel's filtering was promoted under low-velocity flowing conditions. The relationship between filtration rate and multiple factors was explicable using our pump mussel model, which could be simplified to reveal the effect of each single factor. The model shows superior mechanical explanations and better accuracy performance compare to previous statistical models.
Schlagwörter	Golden mussel ; Filtration rate ; Mussel pump model ; Temperature ; Shell length ; Ecology ; QH540-549.5
Sprache	Englisch
Erscheinungsdatum	2024-01-01T00:00:00Z
Verlag	Elsevier
Dokumenttyp	Artikel ; Online
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Buch ; Online: Private Enterprise in China

Song, Ligang / Wang, Xiaolu / Yao, Yang / Garnaut, Ross

2012

Abstract: The Chinese economy is currently undergoing a profound institutional transformation-a quiet revolution. In a regulated environment geared to the requirements of state-owned enterprises, the successs of the private sector as the main focus for economic ... ...

Abstract	The Chinese economy is currently undergoing a profound institutional transformation-a quiet revolution. In a regulated environment geared to the requirements of state-owned enterprises, the successs of the private sector as the main focus for economic growth is remarkable. State-owned enterprises are currently being restructured based on market conditions in which private firms are now permitted to play an important role. Fascinated by the implications of this reform within the Chinese economy, the Asia-Pacific School of Economics and Management of The Australian National University, in conjunction with the China Center for Economic Research of Peking University research team, conducted a large sample survey. Four study sites were chosen: Beijing, Chengdu, Shunde and Wenzhou. Leading economists analyse the nature and dynamics of private sector reform within the Chinese economy and make recommendations for policy which support opportunities for growth and investment. This work, originally published by Asia Pacific Press, is reproduced here in the interests of maintaining open access to high-quality academic works no longer in print
Schlagwörter	Economic theory. Demography
Umfang	1 electronic resource ( p.)
Verlag	ANU Press
Dokumenttyp	Buch ; Online
Anmerkung	English ; Open Access
HBZ-ID	HT020088671
ISBN	9781922144478 ; 1922144479
Datenquelle	ZB MED Katalog Medizin, Gesundheit, Ernährung, Umwelt, Agrar

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Artikel ; Online: Water-lipid interface in lipidic mesophases with excess water.

Yao, Yang / Catalini, Sara / Foggi, Paolo / Mezzenga, Raffaele

Faraday discussions

2024 Band 249, Seite(n) 469–484

Abstract: This study investigates the influence of excess water on the lipidic mesophase during the phase transition from diamond cubic phase ( ...

Abstract	This study investigates the influence of excess water on the lipidic mesophase during the phase transition from diamond cubic phase (
Sprache	Englisch
Erscheinungsdatum	2024-02-06
Erscheinungsland	England
Dokumenttyp	Journal Article
ISSN	1364-5498
ISSN (online)	1364-5498
DOI	10.1039/d3fd00118k
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Tree species classification improves the estimation of BVOCs from urban greenspace.

Bao, Xinxin / Zhou, Weiqi / Wang, Weimin / Yao, Yang / Xu, Linli

The Science of the total environment

2024 Band 914, Seite(n) 169762

Abstract: Accurate estimation of biogenic volatile organic compounds (BVOCs) emissions from urban plants is important as BVOCs affect the formation of secondary pollutants and human health. However, uncertainties exist for the estimation of BVOCs emissions from ... ...

Abstract	Accurate estimation of biogenic volatile organic compounds (BVOCs) emissions from urban plants is important as BVOCs affect the formation of secondary pollutants and human health. However, uncertainties exist for the estimation of BVOCs emissions from urban greenspace due to the lack of tree species classification with high spatial resolution. Here, we generated a tree species classification dataset with 10 m resolution to estimate tree species-level BVOCs emissions and quantify their impact on air quality in Shenzhen in southern China. The results showed that for the entire city, the BVOCs emissions based on traditional plant functional types (PFTs) dataset were substantially underestimated compared with the tree species classification data (6.37 kt versus 8.23 kt, with 22.60 % difference). The underestimation is particularly prominent in urban built-up areas, where our estimation was 1.65 kt, nearly twice of that based on PFTs data (0.86 kt). BVOCs estimation in built-up areas contributed approximately 20.07 % to the total. These BVOCs contributed substantially to the increase of ambient O
Mesh-Begriff(e)	Humans ; Trees ; Air Pollutants/analysis ; Volatile Organic Compounds/analysis ; Parks, Recreational ; Particulate Matter/analysis ; Plants ; Environmental Pollutants ; Ozone/analysis
Chemische Substanzen	Air Pollutants ; Volatile Organic Compounds ; Particulate Matter ; Environmental Pollutants ; Ozone (66H7ZZK23N)
Sprache	Englisch
Erscheinungsdatum	2024-01-02
Erscheinungsland	Netherlands
Dokumenttyp	Journal Article
ZDB-ID	121506-1
ISSN	1879-1026 ; 0048-9697
ISSN (online)	1879-1026
ISSN	0048-9697
DOI	10.1016/j.scitotenv.2023.169762
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Incidence and risk factors for potential drug-drug interactions in outpatients receiving opioid analgesics.

Chu, Fei / Yao, Yang / Gao, Bei / Huang, Mingzhi / Kong, Lingti

Expert opinion on drug safety

2024 , Seite(n) 1–9

Abstract: Background: Opioids are the most frequently used drugs to treat pain in cancer patients. However opioid analgesics can cause adverse effects and potential drug-drug interaction.: Research design and methods: This cross-sectional retrospective study ... ...

Abstract	Background: Opioids are the most frequently used drugs to treat pain in cancer patients. However opioid analgesics can cause adverse effects and potential drug-drug interaction. Research design and methods: This cross-sectional retrospective study analyzed pDDI in 1839 patients with opioid analgesics in a large comprehensive hospital in China from January 1 to 31 December 2022. Three drug interaction databases were used to screen for pDDI including Drugs (U.S.A.), Medscape (U.S.A.), and Drug Assistant of Dingxiangyuan (China). Results: The prevalence of pDDIs among 1839 patients was around 41.27% of 759 patients, and 564 patients (74.31%) with pDDIs were diagnosed with tumor. Further, the total of 275 various pDDIs combinations were identified. The combination of oxycodone with morphine had the most frequent occurrence of 229 times, and its adverse effects mainly related to exacerbate central respiratory depression. While, gender, tumor, number of diagnoses, and the variety of opioid analgesics used were independent risk factors for pDDIs. Conclusions: Outpatients taking opioid analgesics had a higher incidence of pDDIs. As consequently, optimized monitoring and management of patients taking opioid analgesics is recommended in order to ensure patient medication safety.
Sprache	Englisch
Erscheinungsdatum	2024-04-23
Erscheinungsland	England
Dokumenttyp	Journal Article
ZDB-ID	2088728-0
ISSN	1744-764X ; 1474-0338
ISSN (online)	1744-764X
ISSN	1474-0338
DOI	10.1080/14740338.2024.2346101
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Establishment risk of invasive golden mussel in a water diversion project

Yao Yang / Mengzhen Xu / Xingyu Chen / Jiahao Zhang / Shulei Wang / Jianying Zhu / Xudong Fu

Environmental Science and Ecotechnology, Vol 17, Iss , Pp 100305- (2024)

An assessment framework

1481

Abstract: Inter-basin water diversion projects have led to accelerated colonization of aquatic organisms, including the freshwater golden mussel (Limnoperna fortunei), exacerbating global biofouling concerns. While the influence of environmental factors on the ... ...

Abstract	Inter-basin water diversion projects have led to accelerated colonization of aquatic organisms, including the freshwater golden mussel (Limnoperna fortunei), exacerbating global biofouling concerns. While the influence of environmental factors on the mussel's invasion and biofouling impact has been studied, quantitative correlations and underlying mechanisms remain unclear, particularly in large-scale inter-basin water diversion projects with diverse hydrodynamic and environmental conditions. Here, we examine the comprehensive impact of environmental variables on the establishment risk of the golden mussel in China's 1432-km-long Middle Route of the South-to-North Water Diversion Project. Logistic regression and multiclass classification models were used to investigate the environmental influence on the occurrence probability and reproductive density of the golden mussel. Total nitrogen, ammonia nitrogen, water temperature, pH, and velocity were identified as crucial environmental variables affecting the biofouling risk in the project. Logistic regression analysis revealed a negative correlation between the occurrence probability of all larval stages and levels of total nitrogen and ammonia nitrogen. The multiclass classification model showed that elevated levels of total nitrogen hindered mussel reproduction, while optimal water temperature enhanced their reproductive capacity. Appropriate velocity and pH levels were crucial in maintaining moderate larval density. This research presents a quantitative analytical framework for assessing establishment risks associated with invasive mussels, and the framework is expected to enhance invasion management and mitigate biofouling issues in water diversion projects worldwide.
Schlagwörter	Golden mussel ; Environmental variables ; Multiclass classification ; Logistic regression ; Quantitative risk assessment ; Environmental sciences ; GE1-350 ; Environmental technology. Sanitary engineering ; TD1-1066
Thema/Rubrik (Code)	333
Sprache	Englisch
Erscheinungsdatum	2024-01-01T00:00:00Z
Verlag	Elsevier
Dokumenttyp	Artikel ; Online
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Artikel ; Online: High-intensity interval training improves cognitive impairment of vascular dementia rats by up-regulating expression of brain-derived neurotrophic factor in the hippocampus.

Guo, Chengcheng / Yao, Yang / Ma, Chunchao / Wang, Zhiyun

Neuroreport

2023 Band 34, Heft 8, Seite(n) 411–418

Abstract: The present study aims to investigate the effect and its potential mechanism of high-intensity intermittent training (HIIT) on cognitive function in vascular dementia (VD) rats. The VD rats with the cognitive impairment were induced by bilateral common ... ...

Abstract	The present study aims to investigate the effect and its potential mechanism of high-intensity intermittent training (HIIT) on cognitive function in vascular dementia (VD) rats. The VD rats with the cognitive impairment were induced by bilateral common carotid artery occlusion (BCCAO), and the ones in the moderate-intensity continuous training (MICT) group and HIIT group received MICT or HIIT for 5 consecutive weeks, respectively. The swimming speed, endurance, and grip strength of rats were all measured after training. The effect and mechanisms of HIIT on ameliorating the cognitive dysfunction were further evaluated by the Morris water maze test, histomorphological analysis, and Western blot analysis. As a result, no significant difference in motor function between VD rats and sham rats was observed. After 5-week HIIT, the motor function of VD rats was significantly enhanced. The results of the Morris water maze test revealed that HIIT significantly reduced escape latency as well as distance to find the platform compared with the sedentary control group (SED group), indicating the improvement in cognitive function. In addition, the hippocampal tissue damage of VD rats measured by H&E staining was markedly ameliorated after 5-week HIIT. Moreover, brain-derived neurotrophic factor (BDNF) expression level in the cerebral cortex and hippocampus tissue detected by Western blot were significantly up-regulated in HIIT group compared to SED group and MICT group. In conclusion, HIIT can improve BCCAO-induced cognitive impairment via up-regulating BDNF expression in VD rats.
Mesh-Begriff(e)	Rats ; Animals ; Brain-Derived Neurotrophic Factor/metabolism ; High-Intensity Interval Training/methods ; Dementia, Vascular/therapy ; Dementia, Vascular/metabolism ; Hippocampus/metabolism ; Cognitive Dysfunction/etiology ; Cognitive Dysfunction/therapy ; Cognitive Dysfunction/metabolism
Chemische Substanzen	Brain-Derived Neurotrophic Factor
Sprache	Englisch
Erscheinungsdatum	2023-04-25
Erscheinungsland	England
Dokumenttyp	Journal Article
ZDB-ID	1049746-8
ISSN	1473-558X ; 0959-4965
ISSN (online)	1473-558X
ISSN	0959-4965
DOI	10.1097/WNR.0000000000001903
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Focus on Marine Animal Safety and Marine Bioresources in Response to the SARS-CoV-2 Crisis

Yao Yang / Jiacheng Li / Fang Han

International Journal of Molecular Sciences, Vol 23, Iss 15136, p

2022 Band 15136

Abstract: SARS-CoV-2 as a zoonotic virus has significantly affected daily life and social behavior since its outbreak in late 2019. The concerns over its transmission through different media directly or indirectly have evoked great attention about the survival of ... ...

Abstract	SARS-CoV-2 as a zoonotic virus has significantly affected daily life and social behavior since its outbreak in late 2019. The concerns over its transmission through different media directly or indirectly have evoked great attention about the survival of SARS-CoV-2 virions in the environment and its potential infection of other animals. To evaluate the risk of infection by SARS-CoV-2 and to counteract the COVID-19 disease, extensive studies have been performed to understand SARS-CoV-2 biogenesis and its pathogenesis. This review mainly focuses on the molecular architecture of SARS-CoV-2, its potential for infecting marine animals, and the prospect of drug discovery using marine natural products to combat SARS-CoV-2. The main purposes of this review are to piece together progress in SARS-CoV-2 functional genomic studies and antiviral drug development, and to raise our awareness of marine animal safety on exposure to SARS-CoV-2.
Schlagwörter	marine metabolites ; anti-SARS-CoV-2 ; COVID-19 ; drug development ; marine mammals ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
Thema/Rubrik (Code)	333
Sprache	Englisch
Erscheinungsdatum	2022-12-01T00:00:00Z
Verlag	MDPI AG
Dokumenttyp	Artikel ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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