LIVIVO - Search results -

Search results

Result 1 - 10 of total 63

Search options

Article: Mechanisms of angiogenesis in tumour.

Zhang, Run / Yao, Yutong / Gao, Hanwei / Hu, Xin

2024 Volume 14, Page(s) 1359069

Abstract: Angiogenesis is essential for tumour growth and metastasis. Antiangiogenic factor-targeting drugs have been approved as first line agents in a variety of oncology treatments. Clinical drugs frequently target the VEGF signalling pathway during sprouting ... ...

Abstract	Angiogenesis is essential for tumour growth and metastasis. Antiangiogenic factor-targeting drugs have been approved as first line agents in a variety of oncology treatments. Clinical drugs frequently target the VEGF signalling pathway during sprouting angiogenesis. Accumulating evidence suggests that tumours can evade antiangiogenic therapy through other angiogenesis mechanisms in addition to the vascular sprouting mechanism involving endothelial cells. These mechanisms include (1) sprouting angiogenesis, (2) vasculogenic mimicry, (3) vessel intussusception, (4) vascular co-option, (5) cancer stem cell-derived angiogenesis, and (6) bone marrow-derived angiogenesis. Other non-sprouting angiogenic mechanisms are not entirely dependent on the VEGF signalling pathway. In clinical practice, the conversion of vascular mechanisms is closely related to the enhancement of tumour drug resistance, which often leads to clinical treatment failure. This article summarizes recent studies on six processes of tumour angiogenesis and provides suggestions for developing more effective techniques to improve the efficacy of antiangiogenic treatment.
Language	English
Publishing date	2024-03-25
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2649216-7
ISSN	2234-943X
ISSN	2234-943X
DOI	10.3389/fonc.2024.1359069
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Article ; Online: Integrated clinical and prognostic analyses of mTOR/Hippo pathway core genes in hepatocellular carcinoma.

Feng, Tianhang / Chen, Ping / Wang, Tao / Lai, Chunyou / Yao, Yutong

Journal of physiology and biochemistry

2024 Volume 80, Issue 2, Page(s) 439–449

Abstract: Hepatocellular carcinoma (HCC) is one of the most aggressive and dismal cancers globally. Emerging evidence has established that mTOR and Hippo pathways are oncogenic drivers of HCC. However, the prognostic value of these pathways in HCC remains unclear. ...

Abstract	Hepatocellular carcinoma (HCC) is one of the most aggressive and dismal cancers globally. Emerging evidence has established that mTOR and Hippo pathways are oncogenic drivers of HCC. However, the prognostic value of these pathways in HCC remains unclear. In this study, we aimed to develop a gene signature utilizing the mTOR/Hippo genes for HCC prognostication. A multiple stage strategy was employed to screen, and a 12-gene signature based on mTOR/Hippo pathways was constructed to predict the prognosis of HCC patients. The risk scores calculated by the signature were inversely correlated with patient prognosis. Validation of the signature in independent cohort confirmed its predictive power. Further analysis revealed molecular differences between high and low-risk groups at genomic, transcriptomic, and protein-interactive levels. Moreover, immune infiltration analysis revealed an immunosuppressive state in the high-risk group. Finally, the gene signature could predict the sensitivity to current chemotherapeutic drugs. This study demonstrated that combinatorial mTOR/Hippo gene signature was a robust and independent prognostic tool for survival prediction of HCC. Our findings not only provide novel insights for the molecular understandings of mTOR/Hippo pathways in HCC, but also have important clinical implications for guiding therapeutic strategies.
MeSH term(s)	Humans ; Liver Neoplasms/genetics ; Liver Neoplasms/mortality ; Liver Neoplasms/metabolism ; Carcinoma, Hepatocellular/genetics ; Carcinoma, Hepatocellular/mortality ; Carcinoma, Hepatocellular/metabolism ; Carcinoma, Hepatocellular/pathology ; TOR Serine-Threonine Kinases/metabolism ; TOR Serine-Threonine Kinases/genetics ; Prognosis ; Gene Expression Regulation, Neoplastic ; Female ; Hippo Signaling Pathway ; Male ; Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Signal Transduction ; Protein Serine-Threonine Kinases/genetics ; Protein Serine-Threonine Kinases/metabolism ; Middle Aged ; Gene Expression Profiling ; Transcriptome
Chemical Substances	TOR Serine-Threonine Kinases (EC 2.7.11.1) ; MTOR protein, human (EC 2.7.1.1) ; Biomarkers, Tumor ; Protein Serine-Threonine Kinases (EC 2.7.11.1)
Language	English
Publishing date	2024-03-12
Publishing country	Spain
Document type	Journal Article
ZDB-ID	1325104-1
ISSN	1877-8755 ; 0034-9402 ; 1138-7548
ISSN (online)	1877-8755
ISSN	0034-9402 ; 1138-7548
DOI	10.1007/s13105-024-01015-0
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 198: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Evaluating the response and adaptation of urban stormwater systems to changed rainfall with the CMIP6 projections.

Yao, Yutong / Li, Jiake / Jiang, Yishuo / Huang, Guoru

Journal of environmental management

2023 Volume 347, Page(s) 119135

Abstract: Climate change is altering urban rainfall characteristics, leading to extreme urban stormwater and, particularly, more frequent flooding. Due to the uncertainty of climate change, the responses of urban drainage systems to climate change are becoming ... ...

Abstract	Climate change is altering urban rainfall characteristics, leading to extreme urban stormwater and, particularly, more frequent flooding. Due to the uncertainty of climate change, the responses of urban drainage systems to climate change are becoming more complicated. This complexity makes it difficult for decision makers to assess whether urban infrastructure is sufficiently resilient to cope with flood risks. In this study, the Xiao Zhai area, a high-density urban area of China, was used as an example. A quantitative method for assessing these risks and the resilience of urban drainage systems to future urban stormwater was developed. First, based on the Coupled Model Intercomparison Project Phase 6 (CMIP6), the variation and uncertainty of future rainfall in the study area were analysed. A high-fidelity hydro-hydraulic model was developed to analyse the influence of climate change on future urban stormwater. Finally, the relationship between urban flood risk and the resilience of urban drainage systems was evaluated. The results show that the temporal distribution of future rainfall from 2023 to 2100 is relatively uniform. However, the number of heavy rainfall events increases significantly during this period. The flood risk caused by future rainfall was one level higher than the historical flood risk. For example, the flood risk caused by future 5a rainfall is equal to the flood risk from historical 10a rainfall. The correlations between the spatial distributions of flood risk and resilience are 0.49-0.63. Urban drainage systems urgently need to be improved and refined in areas with flood risk and low resilience to become more resilient to climate change. Rational planning of grey-green rainwater facilities in flood risk and low resilience areas can improve the rainwater system's resilience to 0.67-0.95 for climate change.
MeSH term(s)	Floods ; Uncertainty ; Forecasting ; Climate Change ; China ; Cities
Language	English
Publishing date	2023-10-03
Publishing country	England
Document type	Journal Article
ZDB-ID	184882-3
ISSN	1095-8630 ; 0301-4797
ISSN (online)	1095-8630
ISSN	0301-4797
DOI	10.1016/j.jenvman.2023.119135
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 7556: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Risk Assessment and Management Method of Urban Flood Disaster

Li, Jiake / Gao, Jiayu / Li, Ning / Yao, Yutong / Jiang, Yishuo

Water Resour Manage. 2023 Mar., v. 37, no. 5 p.2001-2018

2023

Abstract: Due to the failure of flood control and drainage infrastructure to match the rapidly growing urbanization process, urban flooding has become one of the most significant disasters faced today. It is essential to carry out the risk assessment of flood ... ...

Abstract	Due to the failure of flood control and drainage infrastructure to match the rapidly growing urbanization process, urban flooding has become one of the most significant disasters faced today. It is essential to carry out the risk assessment of flood scientifically and study the optimal allocation of stormwater infrastructure in-depth. In this paper, a complete urban flooding risk assessment and management methodology is proposed by linking “scenario simulation”, “risk assessment” and “allocation optimization”, which is applied in Xiaozhai area of Xi’an, China. Based on the measured data and the results of the maximum water depth survey, an accurate coupled model of flooding in the study area was established, which was used to simulate the current situation and design scenarios. On the basis of the “hazard-vulnerability” framework, a multi-factor flood risk levels were assessed, and four risk gradations were mapped. Taking the results of risk analysis as the point of view, the allocation-effect functions are fitted by the polynomial curves and consisted as a part of objective function. Then, the optimal scenario is obtained by NSGA-III. The results show that the urban flood risk zoning is accurately screened, and the optimal scenario increases the runoff control rate from 54 to 85% compared with the traditional development scenario. The regional risk-free area doubles, the low-risk and medium-risk areas are reduced by a factor of 2 and 16, and the high-risk are all eliminated, with significant flood control effects. The cost savings are 127 million CNY compared to the initial scenario without optimization. The overall idea starts from flood formation, which provides a research method that can be applied to regions with similar problems.
Keywords	drainage ; flood control ; infrastructure ; models ; risk ; risk assessment ; stormwater ; surveys ; urbanization ; China
Language	English
Dates of publication	2023-03
Size	p. 2001-2018.
Publishing place	Springer Netherlands
Document type	Article ; Online
ZDB-ID	59924-4
ISSN	1573-1650 ; 0920-4741
ISSN (online)	1573-1650
ISSN	0920-4741
DOI	10.1007/s11269-023-03467-3
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Bonn / Germany

Z 6155: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾
- See ZB MED holdings
- Order with fees

Article: An Orthotopic Resection Surgical Technique Using an Inferior Infracolic Approach for Laparoscopic Pancreaticoduodenectomy.

Yao, Yutong / Xiong, Junjie / Wang, Ziyao / Wang, Xing / Liu, Xubao / Ke, Nengwen

Journal of clinical medicine

2023 Volume 12, Issue 2

Abstract: The no-touch isolation technique has been widely used in cancer surgery as a strategy to prevent cancer cells from spreading; however, it is difficult to apply in laparoscopic pancreaticoduodenectomy (LPD). Here, we describe an orthotopic resection ... ...

Abstract	The no-touch isolation technique has been widely used in cancer surgery as a strategy to prevent cancer cells from spreading; however, it is difficult to apply in laparoscopic pancreaticoduodenectomy (LPD). Here, we describe an orthotopic resection surgical technique that applies a no-touch principle for LPD and can help with the in situ resection of tumors. In implementing this surgical strategy, Kocher's maneuver was not performed first. Instead, after the exploration of the abdominal cavity, the distal stomach and the pancreatic neck were transected. Then, the dissection of the uncinate process of the pancreas, the duodenum, and the superior mesenteric vein and artery is carried out via an inferior infracolic approach. Finally, the pancreatic head and duodenum were removed in situ. Among the 41 patients who underwent this technique, two (4.9%) required conversion to open surgery due to uncontrolled bleeding. The average operative time was 335 min (248-1055 min). The mean estimated blood loss was 300 mL (50-1250 mL). Two patients (4.9%) underwent combined PV resection and reconstruction; six patients (14.6%) required a blood transfusion; two patients (4.9%) suffered from postoperative bleeding; two patients (4.9%) suffered from Grade B pancreatic fistulas; one patient (2.4%) suffered from bile leakage; and three patients (7.3%) suffered from abdominal fluid collection. No patients died during the perioperative period. Therefore, orthotopic LPD using an inferior infracolic approach is safe and feasible for patients with malignant pancreatic head and periampullary tumors. However, further investigations are required to elucidate its oncological benefits.
Language	English
Publishing date	2023-01-11
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12020590
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Comprehensive analysis of waterlogging control and carbon emission reduction for optimal LID layout: a case study in campus.

Su, Jinghui / Li, Jiake / Gao, Xujun / Yao, Yutong / Jiang, Chunbo

Environmental science and pollution research international

2022 Volume 29, Issue 58, Page(s) 87802–87816

Abstract: Nowadays, sponge city reconstruction has become the focus of research because of the increasingly serious urban waterlogging. Carbon emission reduction, waterlogging area reduction, cost, and other indicators were considered to explore the optimal sponge ...

Abstract	Nowadays, sponge city reconstruction has become the focus of research because of the increasingly serious urban waterlogging. Carbon emission reduction, waterlogging area reduction, cost, and other indicators were considered to explore the optimal sponge allocation scheme in the study area. The two-dimensional coupled model MIKE FLOOD was established to analyze the causes of waterlogging through numerical simulation. Low-impact development (LID) combination scenarios were set to analyze the control effects of waterlogging water and total runoff. The carbon emission reduction capacity and economic benefit of each scenario were calculated and evaluated. The analytic hierarchy process (AHP) was used to comprehensively evaluate the LID combination scenario and explore the optimal cost-benefit LID configuration scheme. The results show that the campus rainwater pipe network is under overload operation, and the number of overflow nodes accounts for up to 58.1% under the 3a rainfall return periods. After setting up LID measures, the runoff control rate can be increased by 26.15-42.84%, and the waterlogging area where the depth exceeds 15 cm can be reduced by 72.87-100%. If the energy conservation and emission reduction benefits and costs are considered at the same time, the layout scenario of 9% bioretention facility + 3% green roof + 3% permeable pavement can achieve the best benefits. The research can provide a reference for planning and reconstruction of sponge campus and residential areas.
MeSH term(s)	Rain ; Carbon ; Water Movements ; Cities ; Floods ; China
Chemical Substances	Carbon (7440-44-0)
Language	English
Publishing date	2022-07-12
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-022-21877-5
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 5915: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Construction and application of sponge city resilience evaluation system: a case study in Xi'an, China.

Li, Jiake / Jiang, Yishuo / Zhai, Mengmeng / Gao, Jiayu / Yao, Yutong / Li, Yafang

Environmental science and pollution research international

2023 Volume 30, Issue 22, Page(s) 62051–62066

Abstract: Urban vulnerability is evident when highly complex flood risks overlap with diverse cities, and it is important to enhance the resilience of cities to flood shocks. In this study, a sponge city resilience assessment system is established considering ... ...

Abstract	Urban vulnerability is evident when highly complex flood risks overlap with diverse cities, and it is important to enhance the resilience of cities to flood shocks. In this study, a sponge city resilience assessment system is established considering engineering, environmental and social indicators, and the grey relational analysis method (GRA) is used to quantify sponge city resilience. At the same time, a multi-objective optimization model is established based on the three dimensions of water ecological environment, drainage safety, and waterlogging safety. The optimal configuration of grey-green infrastructure is weighed by combining the ideal point method, aiming to ensure that cities effectively reduce flood risk through the optimal configuration scheme. Taking the Xiaozhai area in Xi'an as the study area, the evaluation results show that the grey relational degree (GRD) of the resilience indexes of the original scheme is between 0.390 and 0.661 under the seven different return periods, while the optimization scheme ranges from 0.648 to 0.765, with the best sponge city resilience at a return period of 2a. Compared with the original scheme, the optimized sponge city resilience level increases from level II to nearly level I in the low return period and from level IV to level II in the high return period, indicating that city's ability to cope with waterlogging and pollution is enhanced significantly. Besides, the main factor affecting the sponge city resilience is the runoff control rate, followed by pollutant load reduction rate, which can provide a methodological framework for the assessment and improvement of sponge city resilience.
MeSH term(s)	Cities ; China ; Environmental Pollutants ; Floods ; Engineering
Chemical Substances	Environmental Pollutants
Language	English
Publishing date	2023-03-18
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1178791-0
ISSN	1614-7499 ; 0944-1344
ISSN (online)	1614-7499
ISSN	0944-1344
DOI	10.1007/s11356-023-26357-y
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 5915: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Correction: Impact of preoperative antiviral therapy on the prognosis of hepatitis B virus-related hepatocellular carcinoma.

Liang, Yuxin / Zhong, Deyuan / Zhang, Zilong / Su, Yuhao / Yan, Su / Lai, Chunyou / Yao, Yutong / Shi, Ying / Huang, Xiaolun / Shang, Jin

BMC cancer

2024 Volume 24, Issue 1, Page(s) 343

Language	English
Publishing date	2024-03-15
Publishing country	England
Document type	Published Erratum
ZDB-ID	2041352-X
ISSN	1471-2407 ; 1471-2407
ISSN (online)	1471-2407
ISSN	1471-2407
DOI	10.1186/s12885-024-12108-w
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Impact of preoperative antiviral therapy on the prognosis of hepatitis B virus-related hepatocellular carcinoma.

Liang, Yuxin / Zhong, Deyuan / Zhang, Zilong / Su, Yuhao / Yan, Su / Lai, Chunyou / Yao, Yutong / Shi, Ying / Huang, Xiaolun / Shang, Jin

BMC cancer

2024 Volume 24, Issue 1, Page(s) 291

Abstract: Background: For chronic hepatitis B virus (HBV) infection patients, increasing evidence has demonstrated the effectiveness of expanding the indications and applicable population for antiviral therapy. However, the expanded indication of antiviral ... ...

Abstract	Background: For chronic hepatitis B virus (HBV) infection patients, increasing evidence has demonstrated the effectiveness of expanding the indications and applicable population for antiviral therapy. However, the expanded indication of antiviral therapy for hepatocellular carcinoma (HCC) remains to be further explored. Methods: 196 HBV-related HCC patients who received radical hepatectomy and nucleos(t)ide analogues (NAs) therapy at Sichuan Provincial People's Hospital were enrolled in this study. HCC recurrence, overall survival (OS), early virological (VR) and biochemical responses (BR) of patients were compared between different NAs therapy and the use of anti-programmed cell death protein 1 (PD-1) therapy. Results: NAs therapy at different timing of surgery was a strong independent risk factor for postoperative recurrence and overall mortality of HBV-related HCC patients. Furthermore, in HCC patients who received postoperative anti-PD-1 therapy, patients with HBV DNA < 1000 copy/mL had significantly better recurrence-free survival (RFS) and OS than those with HBV DNA ≥ 1000 copy/mL (HR: 7.783; P = 0.002; HR: 6.699; P < 0.001). However, the differences of RFS and OS rates between entecavir group and tenofovir disoproxil fumarate group were not statistically significant. Similar results were also observed in the rates of early VR, BR and combined VR and BR. Conclusion: Timely and reasonable preoperative NAs therapy showed clinical benefit in improving the prognosis of patients with HBV-related HCC, even in the case of normal alanine aminotransferase (ALT) level and negative hepatitis e antigen (HBeAg). Furthermore, a possible synergistic effect between antiviral therapy and anti-PD-1 therapy was founded and need further verification.
MeSH term(s)	Humans ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/surgery ; Hepatitis B virus ; DNA, Viral ; Hepatitis B, Chronic/complications ; Hepatitis B, Chronic/drug therapy ; Liver Neoplasms/drug therapy ; Liver Neoplasms/surgery ; Prognosis ; Antiviral Agents/therapeutic use
Chemical Substances	DNA, Viral ; Antiviral Agents
Language	English
Publishing date	2024-03-04
Publishing country	England
Document type	Journal Article
ZDB-ID	2041352-X
ISSN	1471-2407 ; 1471-2407
ISSN (online)	1471-2407
ISSN	1471-2407
DOI	10.1186/s12885-024-12031-0
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Circulating galectin-3 level association with cardiovascular risk factors during peritoneal dialysis.

Yang, Xuerui / Yang, Jun / Zeng, Youjia / Peng, Ling / Liu, Xingzheng / Mo, Jinying / Wang, Taifen / Yao, Yutong / Zheng, Yihou / Song, Gaofeng

Clinical and experimental nephrology

2024

Abstract: Objective: Cardiovascular disease (CVD) represents the primary cause of mortality in patients afflicted with end-stage renal disease and undergoing peritoneal dialysis (PD) treatment. Galectin-3 (Gal-3), a molecule known to exhibit a correlation with ... ...

Abstract	Objective: Cardiovascular disease (CVD) represents the primary cause of mortality in patients afflicted with end-stage renal disease and undergoing peritoneal dialysis (PD) treatment. Galectin-3 (Gal-3), a molecule known to exhibit a correlation with CVD mortality garners considerable interest. The objective of this study was to explore the potential association between serum Gal-3 levels and other CVD risk factors among PD patients. Methods: In this cross-sectional study, a total of 114 PD patients with a minimum of 3 months of PD treatment were enrolled. Serum Gal-3 levels were quantified using an enzyme-linked immunosorbent assay. The data of patients with Gal-3 levels higher and lower than 26.744 pg/ml were compared using Mann-Whitney U tests or t tests. Pearson's correlation or Spearman's correlation analysis and multivariate regression were used to assess the associations between the known risk factors for CVD and Gal-3. Results: In comparison to the inter-group baseline data, the low Gal-3 group exhibited a higher glomerular filtration rate (GFR). Gal-3 levels correlate positively with PD duration, B-type natriuretic peptide (BNP), growth differentiation factor 15 (GDF-15), interventricular septal thickness in diastolic (IVST), and left ventricular mass index (LVMI). Conversely, Gal-3 exhibited a negative correlation with albumin levels. Multivariate linear regression analysis demonstrated a positive correlation between Gal-3 levels and BNP, GDF-15, PD duration, IVST and LVMI. Gal-3 levels were negatively correlated with albumin levels. Conclusions: Gal-3 was strongly associated with BNP, GDF-15, IVST and LVMI in patients undergoing PD treatment. Prospective studies should be carried out to determine whether Gal-3 can be a promising biomarker in predicting increased risk of adverse cardiovascular events in PD patients.
Language	English
Publishing date	2024-04-20
Publishing country	Japan
Document type	Journal Article
ZDB-ID	1338768-6
ISSN	1437-7799 ; 1342-1751
ISSN (online)	1437-7799
ISSN	1342-1751
DOI	10.1007/s10157-024-02498-3
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4922: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

To top

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito