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  1. Article ; Online: Vitamin D prescribing practices among clinical practitioners during the COVID-19 pandemic.

    Jude, Edward B / Tentolouris, Nikolaos / Rastogi, Ashu / Yap, Moi H / Pedrosa, Hermelinda C / Ling, Stephanie F

    Health science reports

    2022  Volume 5, Issue 4, Page(s) e691

    Abstract: Background and aims: COVID-19 has caused devastation globally. Low vitamin D status, particularly during the winter months, remains commonplace around the world, and it is thought to be one of the contributing factors toward causation and severity of ... ...

    Abstract Background and aims: COVID-19 has caused devastation globally. Low vitamin D status, particularly during the winter months, remains commonplace around the world, and it is thought to be one of the contributing factors toward causation and severity of COVID-19. Many guidelines do not recommend vitamin D for the treatment or prevention of the disease. Hence, we set out to conduct a global survey to understand the use and prescribing habits of vitamin D among clinicians for COVID-19.
    Methods: An online anonymous questionnaire was sent to clinicians enquiring about their prescribing habits of vitamin D and personal use of vitamin D. Data of the survey were collected between January 15, 2021, and February 13, 2021.
    Results: Four thousand four hundred forty practicing clinicians were included in the analysis, with the majority of those responding from Asia, followed by Europe. 82.9% prescribed vitamin D before COVID-19, more commonly among general practitioners (GPs) in comparison with medical specialists, and Asian clinicians were more likely to prescribe vitamin D in comparison with Caucasian physicians (
    Conclusion: This survey has shown that many clinicians would prescribe vitamin D for the prevention and treatment of COVID-19. The majority would also recommend measuring vitamin D levels, but not so in patients with COVID-19.
    Language English
    Publishing date 2022-07-11
    Publishing country United States
    Document type Journal Article
    ISSN 2398-8835
    ISSN (online) 2398-8835
    DOI 10.1002/hsr2.691
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Artificial intelligence and soft skills in radiation oncology: Data versus wisdom.

    Boon, Ian S / Lim, Jean S / Yap, Moi H / Au Yong, Tracy P T / Boon, Cheng S

    Journal of medical imaging and radiation sciences

    2020  Volume 51, Issue 4S, Page(s) S114–S115

    MeSH term(s) Artificial Intelligence ; COVID-19/epidemiology ; Decision Making ; Humans ; Pandemics ; Patient Care Team ; Precision Medicine ; Radiation Oncology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-08-25
    Publishing country United States
    Document type Letter
    ZDB-ID 2426513-5
    ISSN 1876-7982 ; 1939-8654
    ISSN (online) 1876-7982
    ISSN 1939-8654
    DOI 10.1016/j.jmir.2020.08.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Radiomics: Quantitative Radiology transforming Oncology Care.

    Boon, Ian S / Yap, Moi H / Au Yong, Tracy P T / Boon, Cheng S

    The British journal of radiology

    2020  Volume 93, Issue 1111, Page(s) 20200333

    MeSH term(s) Evaluation Studies as Topic ; Forecasting ; Humans ; Image Interpretation, Computer-Assisted/methods ; Magnetic Resonance Imaging/methods ; Multimodal Imaging/methods ; Multimodal Imaging/trends ; Positron Emission Tomography Computed Tomography/methods ; Radiation Oncology/methods ; Radiation Oncology/trends ; United Kingdom
    Language English
    Publishing date 2020-05-06
    Publishing country England
    Document type Letter
    ZDB-ID 2982-8
    ISSN 1748-880X ; 0007-1285
    ISSN (online) 1748-880X
    ISSN 0007-1285
    DOI 10.1259/bjr.20200333
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  4. Article ; Online: Interpreting clinical significance of machine learning approaches and radiomics in radiation oncology trials.

    Boon, Ian S / Yap, Moi H / Au Yong, Tracy P T / Boon, Cheng S

    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

    2020  Volume 152, Page(s) 78–79

    MeSH term(s) Humans ; Lymphatic Metastasis ; Machine Learning ; Radiation Oncology ; Stomach Neoplasms
    Language English
    Publishing date 2020-07-27
    Publishing country Ireland
    Document type Letter ; Comment
    ZDB-ID 605646-5
    ISSN 1879-0887 ; 0167-8140
    ISSN (online) 1879-0887
    ISSN 0167-8140
    DOI 10.1016/j.radonc.2020.07.042
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  5. Article: Artificial intelligence and soft skills in radiation oncology: Data versus wisdom

    Boon, Ian S / Lim, Jean S / Yap, Moi H / Au Yong, Tracy P T / Boon, Cheng S

    Journal of medical imaging and radiation sciences (Online)

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #731412
    Database COVID19

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  6. Article: Validation of a New Semi-Automated Technique to Evaluate Muscle Capillarization.

    Ballak, Sam B / Yap, Moi H / Harding, Peter J / Degens, Hans

    Advances in experimental medicine and biology

    2016  Volume 876, Page(s) 87–93

    Abstract: The method of capillary domains has often been used to study capillarization of skeletal and heart muscle. However, the conventional data processing method using a digitizing tablet is an arduous and time-consuming task. Here we compare a new semi- ... ...

    Abstract The method of capillary domains has often been used to study capillarization of skeletal and heart muscle. However, the conventional data processing method using a digitizing tablet is an arduous and time-consuming task. Here we compare a new semi-automated capillary domain data collection and analysis in muscle tissue with the standard capillary domain method. The capillary density (1481±59 vs. 1447±54 caps mm(-2); R2:0.99; P<0.01) and heterogeneity of capillary spacing (0.085±0.002 vs. 0.085±0.002; R2:0.95; P<0.01) were similar in both methods. The fiber cross-sectional area correlated well between the methods (R2:0.84; P<0.01) and did not differ significantly (~8% larger in the old than new method at P=0.08). The latter was likely due to differences in outlining the contours between the two methods. In conclusion, the semi-automated method gives quantitatively and qualitatively similar data as the conventional method and saves a considerable amount of time.
    MeSH term(s) Animals ; Capillaries/physiology ; Data Collection ; Mice ; Mice, Inbred C57BL ; Muscle, Skeletal/blood supply ; Statistics as Topic
    Language English
    Publishing date 2016
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Validation Studies
    ISSN 2214-8019 ; 0065-2598
    ISSN (online) 2214-8019
    ISSN 0065-2598
    DOI 10.1007/978-1-4939-3023-4_11
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Blunted angiogenesis and hypertrophy are associated with increased fatigue resistance and unchanged aerobic capacity in old overloaded mouse muscle.

    Ballak, Sam B / Busé-Pot, Tinelies / Harding, Peter J / Yap, Moi H / Deldicque, Louise / de Haan, Arnold / Jaspers, Richard T / Degens, Hans

    Age (Dordrecht, Netherlands)

    2016  Volume 38, Issue 2, Page(s) 39

    Abstract: We hypothesize that the attenuated hypertrophic response in old mouse muscle is (1) partly due to a reduced capillarization and angiogenesis, which is (2) accompanied by a reduced oxidative capacity and fatigue resistance in old control and overloaded ... ...

    Abstract We hypothesize that the attenuated hypertrophic response in old mouse muscle is (1) partly due to a reduced capillarization and angiogenesis, which is (2) accompanied by a reduced oxidative capacity and fatigue resistance in old control and overloaded muscles, that (3) can be rescued by the antioxidant resveratrol. To investigate this, the hypertrophic response, capillarization, oxidative capacity, and fatigue resistance of m. plantaris were compared in 9- and 25-month-old non-treated and 25-month-old resveratrol-treated mice. Overload increased the local capillary-to-fiber ratio less in old (15 %) than in adult (59 %) muscle (P < 0.05). Although muscles of old mice had a higher succinate dehydrogenase (SDH) activity (P < 0.05) and a slower fiber type profile (P < 0.05), the isometric fatigue resistance was similar in 9- and 25-month-old mice. In both age groups, the fatigue resistance was increased to the same extent after overload (P < 0.01), without a significant change in SDH activity, but an increased capillary density (P < 0.05). Attenuated angiogenesis during overload may contribute to the attenuated hypertrophic response in old age. Neither was rescued by resveratrol supplementation. Changes in fatigue resistance with overload and aging were dissociated from changes in SDH activity, but paralleled those in capillarization. This suggests that capillarization plays a more important role in fatigue resistance than oxidative capacity.
    MeSH term(s) Aging ; Animals ; Disease Models, Animal ; Fatigue/metabolism ; Fatigue/pathology ; Fatigue/physiopathology ; Hypertrophy ; Male ; Mice ; Mice, Inbred C57BL ; Muscle Fatigue ; Muscle, Skeletal/pathology ; Muscle, Skeletal/physiopathology ; Neovascularization, Pathologic/pathology ; Physical Exertion
    Language English
    Publishing date 2016-04
    Publishing country Netherlands
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 423714-6
    ISSN 1574-4647 ; 0161-9152
    ISSN (online) 1574-4647
    ISSN 0161-9152
    DOI 10.1007/s11357-016-9894-1
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