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  1. Article: [Immunobiology of dust mite allergens and allergic disease].

    Yasueda, Hiroshi

    Arerugi = [Allergy

    2008  Volume 57, Issue 7, Page(s) 807–815

    MeSH term(s) Air Pollution, Indoor/prevention & control ; Animals ; Antigens, Dermatophagoides/immunology ; Humans ; Hypersensitivity/immunology ; Pyroglyphidae/immunology
    Chemical Substances Antigens, Dermatophagoides
    Language Japanese
    Publishing date 2008-07
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 974201-3
    ISSN 0021-4884
    ISSN 0021-4884
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: [Characterization of allergens and their clinical application].

    Yasueda, Hiroshi

    Arerugi = [Allergy

    2007  Volume 56, Issue 10, Page(s) 1249–1253

    MeSH term(s) Allergens/immunology ; Allergens/isolation & purification ; Aspergillosis, Allergic Bronchopulmonary/diagnosis ; Biomarkers/blood ; Cross Reactions ; Diagnosis, Differential ; Humans ; Hypersensitivity/diagnosis ; Hypersensitivity/immunology ; Immunoglobulin E/blood
    Chemical Substances Allergens ; Biomarkers ; Immunoglobulin E (37341-29-0)
    Language Japanese
    Publishing date 2007-10
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 974201-3
    ISSN 0021-4884
    ISSN 0021-4884
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Quantitative analysis of environmental allergens and its significance].

    Yasueda, Hiroshi

    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine

    2003  Volume 93, Issue 10, Page(s) 2130–2136

    MeSH term(s) Allergens/analysis ; Animals ; Asthma/diagnosis ; Environmental Pollutants/analysis ; Humans ; Hypersensitivity/diagnosis ; Mites/immunology
    Chemical Substances Allergens ; Environmental Pollutants
    Language Japanese
    Publishing date 2003-07-08
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 952816-7
    ISSN 1883-2083 ; 0021-5384
    ISSN (online) 1883-2083
    ISSN 0021-5384
    DOI 10.2169/naika.93.2130
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Serological diagnosis of allergic bronchopulmonary mycosis: Progress and challenges.

    Fukutomi, Yuma / Tanimoto, Hidenori / Yasueda, Hiroshi / Taniguchi, Masami

    Allergology international : official journal of the Japanese Society of Allergology

    2016  Volume 65, Issue 1, Page(s) 30–36

    Abstract: Prompt diagnosis of allergic bronchopulmonary mycosis (ABPM) is an important clinical issue in preventing irreversible lung damage. Therefore, a good serological marker for the diagnosis of ABPM is desired in clinical practice. The measurement of IgE ... ...

    Abstract Prompt diagnosis of allergic bronchopulmonary mycosis (ABPM) is an important clinical issue in preventing irreversible lung damage. Therefore, a good serological marker for the diagnosis of ABPM is desired in clinical practice. The measurement of IgE antibody to crude Aspergillus fumigatus allergen is considered the first step in screening asthmatic patients for allergic bronchopulmonary aspergillosis (ABPA). However, presence of IgE to A. fumigatus does not always indicate genuine sensitization to A. fumigatus because of cross-reactivity between crude extracts from different fungal sources. The application of molecular-based allergy diagnosis can solve this problem. The specificity of testing can be greatly improved by measuring the IgE antibody to Asp f 1 and f 2, specific allergen components for genuine A. fumigatus allergy. The problem of cross-reactivity between crude fungal extracts is also true for the identification of genuine causal fungi in each ABPM patient. Some patients with ABPM induced by fungi other than Aspergillus may be consistent with ABPA diagnostic criteria because current criteria depend on IgE/IgG reactivity to crude extracts. Accurate identification of genuine causal fungi for ABPM is of clinical importance, considering that clinical presentation, anti-fungal treatment strategies and disease prognosis can be influenced by different causal fungi. The diagnosis of causal fungi can be robustly validated by the confirmation of genuine sensitization to fungi after measuring IgE to specific allergen components, as well as repeated microbiological isolation of the fungi from their airway.
    MeSH term(s) Allergens/immunology ; Antibodies, Fungal/immunology ; Antibody Specificity/immunology ; Antigens, Fungal/immunology ; Aspergillosis, Allergic Bronchopulmonary/diagnosis ; Aspergillosis, Allergic Bronchopulmonary/etiology ; Aspergillus fumigatus/genetics ; Aspergillus fumigatus/immunology ; Cross Reactions/immunology ; Humans ; Immunoglobulin E/immunology ; Immunoglobulin G/immunology ; Molecular Diagnostic Techniques ; Serologic Tests/methods
    Chemical Substances Allergens ; Antibodies, Fungal ; Antigens, Fungal ; Immunoglobulin G ; Immunoglobulin E (37341-29-0)
    Language English
    Publishing date 2016-01
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 1336498-4
    ISSN 1440-1592 ; 1323-8930
    ISSN (online) 1440-1592
    ISSN 1323-8930
    DOI 10.1016/j.alit.2015.08.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Allergic bronchopulmonary mycosis caused by Penicillium luteum

    Oshikata, Chiyako / Watanabe, Maiko / Saito, Akemi / Yasueda, Hiroshi / Akiyama, Kazuo / Kamata, Yoichi / Tsurikisawa, Naomi

    Medical mycology case reports. 2017 Mar., v. 15

    2017  

    Abstract: A 65-year-old Japanese male had severe bronchial asthma had increased mold-containing sputum. Serum total IgE level had increased to 798 IU/mL and antigen-specific precipitating antibodies to P. luteum and P. notatum were present but not those reactive ... ...

    Abstract A 65-year-old Japanese male had severe bronchial asthma had increased mold-containing sputum. Serum total IgE level had increased to 798 IU/mL and antigen-specific precipitating antibodies to P. luteum and P. notatum were present but not those reactive toward any species of Aspergillus. Chest computed tomography revealed central bronchiectasis and bronchial wall thickness. After antigen-specific provocation with 10mg/mL of P. luteum, the patient developed asthma exacerbation, but not with A. fumigatus. We present a rare case of Penicillium-induced allergic bronchopulmonary mycosis caused by P. luteum.
    Keywords Aspergillus ; Penicillium ; antibodies ; asthma ; blood serum ; case studies ; chest ; immunoglobulin E ; males ; mycology ; mycoses ; patients ; tomography
    Language English
    Dates of publication 2017-03
    Size p. 9-11.
    Publishing place Elsevier B.V.
    Document type Article
    ISSN 2211-7539
    DOI 10.1016/j.mmcr.2016.11.007
    Database NAL-Catalogue (AGRICOLA)

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  6. Article ; Online: Effective allergen avoidance for reducing exposure to house dust mite allergens and improving disease management in adult atopic asthmatics.

    Tsurikisawa, Naomi / Saito, Akemi / Oshikata, Chiyako / Yasueda, Hiroshi / Akiyama, Kazuo

    The Journal of asthma : official journal of the Association for the Care of Asthma

    2016  Volume 53, Issue 8, Page(s) 843–853

    Abstract: Objective: We investigated the best strategy for adult asthmatics to avoid exposure to Dermatophagoides group (Der-1) allergens.: Methods: Adult atopic asthmatics (n = 111) followed a 32-item checklist for avoiding Der-1 allergen exposure. Twenty- ... ...

    Abstract Objective: We investigated the best strategy for adult asthmatics to avoid exposure to Dermatophagoides group (Der-1) allergens.
    Methods: Adult atopic asthmatics (n = 111) followed a 32-item checklist for avoiding Der-1 allergen exposure. Twenty-five patients were excluded through incomplete sampling; 50 remaining patients encased their pillows/futons/mattresses in microfine-fiber covers, 13 used vacuum cleaners with dust-mite-collection nozzles, and 23 acted as non-intervention controls. During August-October 2010 and August-October 2011, dust samples were collected in Petri dishes placed in bedrooms for 2 weeks and from mattresses/futons by using adhesive tape on one morning. A Der-1 level decrease was defined as a mean 2011 Der-1 level of <1 as a ratio of the 2010 level on tape or Petri dish samples. We analyzed the associations between Der-1 level change (by ELISA) and % weekly variability in peak expiratory flow (PEF) or fraction of exhaled nitric oxide (FeNO) after intervention.
    Results: Der-1 levels decreased significantly in the covers group but not the vacuuming group. FeNO levels and PEF variability were unchanged in both groups. In patients whose Petri dish or tape samples showed decreased Der-1 levels, the % PEF variability was lower in 2011 than in 2010, but FeNO levels were unchanged. Three interventions (vacuuming all family members' mattress/futon surfaces at least weekly or after exposure of the futons to sunlight, and floor wiping before vacuuming), plus using covers, were the most effective management strategy in reducing Der-1 levels.
    Conclusions: This environmental and bedding maintenance program may help manage adult atopic asthma.
    MeSH term(s) Adult ; Aged ; Air Pollution, Indoor/analysis ; Air Pollution, Indoor/prevention & control ; Allergens/analysis ; Antigens, Dermatophagoides/analysis ; Arthropod Proteins/analysis ; Asthma/metabolism ; Asthma/physiopathology ; Asthma/prevention & control ; Bedding and Linens ; Cysteine Endopeptidases/analysis ; Disease Management ; Dust/analysis ; Dust/prevention & control ; Environmental Exposure/analysis ; Environmental Exposure/prevention & control ; Female ; Humans ; Hypersensitivity, Immediate/metabolism ; Hypersensitivity, Immediate/physiopathology ; Hypersensitivity, Immediate/prevention & control ; Immunoglobulin E/blood ; Male ; Middle Aged ; Nitric Oxide/metabolism ; Peak Expiratory Flow Rate
    Chemical Substances Allergens ; Antigens, Dermatophagoides ; Arthropod Proteins ; Dust ; Nitric Oxide (31C4KY9ESH) ; Immunoglobulin E (37341-29-0) ; Cysteine Endopeptidases (EC 3.4.22.-) ; Dermatophagoides farinae antigen f 1 (EC 3.4.22.-) ; Dermatophagoides pteronyssinus antigen p 1 (EC 3.4.22.-)
    Language English
    Publishing date 2016-04-06
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603816-5
    ISSN 1532-4303 ; 0277-0903
    ISSN (online) 1532-4303
    ISSN 0277-0903
    DOI 10.3109/02770903.2016.1155218
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Occupational asthma from exposure to rye flour in a Japanese baker.

    Oshikata, Chiyako / Tsurikisawa, Naomi / Saito, Akemi / Yasueda, Hiroshi / Akiyama, Kazuo

    Respirology case reports

    2014  Volume 2, Issue 3, Page(s) 102–104

    Abstract: Three years after beginning employment at a bakery, a 32-year-old Japanese man began experiencing acute asthma exacerbations after exposure to rye flour. Antigen-specific serum IgE antibodies were detected to the albumin and globulin, gliadin, prolamin, ... ...

    Abstract Three years after beginning employment at a bakery, a 32-year-old Japanese man began experiencing acute asthma exacerbations after exposure to rye flour. Antigen-specific serum IgE antibodies were detected to the albumin and globulin, gliadin, prolamin, and glutenin protein fractions of rye flour purified from the crude antigen, but only to the albumin and globulin fraction of wheat flour. The histamine concentration producing one-half maximal effect was lower for all four rye flour fractions than for the wheat flour fractions. After inhalation of the albumin and globulin fraction of rye flour, forced expiratory volume in 1 sec decreased to 77.7% of that pre-provocation. To our knowledge, this is the first report of baker's asthma due to rye flour in Japan.
    Language English
    Publishing date 2014-07-14
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2750180-2
    ISSN 2051-3380
    ISSN 2051-3380
    DOI 10.1002/rcr2.63
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Allergic bronchopulmonary mycosis caused by Penicillium luteum.

    Oshikata, Chiyako / Watanabe, Maiko / Saito, Akemi / Yasueda, Hiroshi / Akiyama, Kazuo / Kamata, Yoichi / Tsurikisawa, Naomi

    Medical mycology case reports

    2016  Volume 15, Page(s) 9–11

    Abstract: A 65-year-old Japanese male had severe bronchial asthma had increased mold-containing sputum. Serum total IgE level had increased to 798 IU/mL and antigen-specific precipitating antibodies to P. luteum and P. notatum were present but not those reactive ... ...

    Abstract A 65-year-old Japanese male had severe bronchial asthma had increased mold-containing sputum. Serum total IgE level had increased to 798 IU/mL and antigen-specific precipitating antibodies to P. luteum and P. notatum were present but not those reactive toward any species of Aspergillus. Chest computed tomography revealed central bronchiectasis and bronchial wall thickness. After antigen-specific provocation with 10 mg/mL of P. luteum, the patient developed asthma exacerbation, but not with A. fumigatus. We present a rare case of Penicillium-induced allergic bronchopulmonary mycosis caused by P. luteum.
    Language English
    Publishing date 2016-12-02
    Publishing country Netherlands
    Document type Journal Article
    ISSN 2211-7539
    ISSN 2211-7539
    DOI 10.1016/j.mmcr.2016.11.007
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  9. Article: [A case presenting anaphylaxis shock after intake of capsule packing cedar pollen].

    Enomoto, Tadao / Morita, Hiroshi / Saito, Akemi / Yasueda, Hiroshi

    Arerugi = [Allergy

    2009  Volume 58, Issue 1, Page(s) 39–44

    Abstract: The prevalence of Japanese cedar pollinosis is high to 26.5%, and it is properly remarked as "national disease" in Japan. General therapy strategies are composed of self-care by using mask or glasses to avoid antigen, and medical-care by using second- ... ...

    Abstract The prevalence of Japanese cedar pollinosis is high to 26.5%, and it is properly remarked as "national disease" in Japan. General therapy strategies are composed of self-care by using mask or glasses to avoid antigen, and medical-care by using second-generation antihistamines or nasal corticosteroid spray. Meanwhile, there are other so-called self-medication patients who utilize health foods but do not consult to any physician. Papilla, commercial name of one kind of those health foods, is a capsular packed with cedar pollen. In February 2007, we experienced a 49-year-old female patient who presented anaphylaxis shock after intake of Papilla capsular. In this case, her special-IgE antibody and histamine release test were both positive to cedar pollen. Although Cry j 1, the major allergen in the Papilla capsular is a small amount, the cause of anaphylaxis can not be reasoned as anything except the pollen contents in this product. In conclusion, it is appropriate to consider it exercise induce anaphylaxis shock due to playing tennis after intake of the capsular.
    MeSH term(s) Anaphylaxis/etiology ; Cedrus ; Female ; Food, Organic/adverse effects ; Humans ; Middle Aged ; Pollen ; Self Medication/adverse effects
    Language Japanese
    Publishing date 2009-01
    Publishing country Japan
    Document type Case Reports ; English Abstract ; Journal Article
    ZDB-ID 974201-3
    ISSN 0021-4884
    ISSN 0021-4884
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: [Molecular cloning of fungal allergens and clinical applications of recombinant allergens in fungal allergy].

    Yasueda, Hiroshi / Takeuchi, Yasuo

    Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology

    2004  Volume 45, Issue 2, Page(s) 71–76

    Abstract: A large number of fungi are associated with allergic disorders. There are many problems in using non-standardized fungal extracts for diagnosis of fungal allergy. These problems can be solved by using genetically engineered recombinant allergens. At ... ...

    Abstract A large number of fungi are associated with allergic disorders. There are many problems in using non-standardized fungal extracts for diagnosis of fungal allergy. These problems can be solved by using genetically engineered recombinant allergens. At present, more than 70 fungal allergens have been cloned and sequenced, and the recombinant forms of several of these are commercially available. Measurement of IgE antibodies to these commercially available recombinant allergens could provide the tools useful for characterizing the differential sensitization pattern in relation to a particular disease and the allergenic cross-reactivity among fungi. Only a limited number of recombinant allergens are available at present, thus further studies on the molecular biology of fungal allergens are needed so that more recombinant allergens can be used in the clinical field.
    MeSH term(s) Allergens ; Cloning, Molecular/methods ; Fungi/immunology ; Humans ; Hypersensitivity/diagnosis ; Recombinant Proteins
    Chemical Substances Allergens ; Recombinant Proteins
    Language Japanese
    Publishing date 2004-04-19
    Publishing country Japan
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 1198792-3
    ISSN 1882-0476 ; 0916-4804
    ISSN (online) 1882-0476
    ISSN 0916-4804
    DOI 10.3314/jjmm.45.71
    Database MEDical Literature Analysis and Retrieval System OnLINE

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