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  1. Article ; Online: Editorial Comment to CHARGE syndrome with both primary and secondary hypogonadism.

    Iwatsuki, Shoichiro / Umemoto, Yukihiro / Yasui, Takahiro

    IJU case reports

    2024  Volume 7, Issue 3, Page(s) 200–201

    Language English
    Publishing date 2024-02-25
    Publishing country Australia
    Document type Editorial
    ISSN 2577-171X
    ISSN (online) 2577-171X
    DOI 10.1002/iju5.12714
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Editorial Comment to Proportion of patients eligible for adjuvant immunotherapy in nonmetastatic clear-cell renal-cell carcinoma treated with radical or partial nephrectomy.

    Naiki, Taku / Yasui, Takahiro

    International journal of urology : official journal of the Japanese Urological Association

    2022  Volume 29, Issue 10, Page(s) 1237–1238

    MeSH term(s) Carcinoma, Renal Cell/pathology ; Carcinoma, Renal Cell/surgery ; Humans ; Immunotherapy ; Kidney Neoplasms/pathology ; Kidney Neoplasms/surgery ; Nephrectomy
    Language English
    Publishing date 2022-09-12
    Publishing country Australia
    Document type Journal Article ; Comment
    ZDB-ID 1328401-0
    ISSN 1442-2042 ; 0919-8172
    ISSN (online) 1442-2042
    ISSN 0919-8172
    DOI 10.1111/iju.15034
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4460: Show issues Location:
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    Zs.MO 278: Show issues

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  3. Article ; Online: Application of ultrasound imaging in the treatment of urinary tract stones.

    Hamamoto, Shuzo / Inoue, Takaaki / Okada, Shinsuke / Taguchi, Kazumi / Yasui, Takahiro

    Journal of medical ultrasonics (2001)

    2023  

    Abstract: Urinary tract stones are a common clinical condition that affect millions of individuals worldwide. The management of these stones has evolved significantly over the past 70 years, and ultrasound imaging has emerged as a valuable tool for diagnosis, ... ...

    Abstract Urinary tract stones are a common clinical condition that affect millions of individuals worldwide. The management of these stones has evolved significantly over the past 70 years, and ultrasound imaging has emerged as a valuable tool for diagnosis, treatment planning, and follow-up. This review aims to provide an overview of the application of ultrasound imaging in the treatment of urinary tract stones, highlighting its advantages, limitations, and current advancements in the field.
    Language English
    Publishing date 2023-08-12
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 1396630-3
    ISSN 1613-2254 ; 0287-0592 ; 1346-4523
    ISSN (online) 1613-2254
    ISSN 0287-0592 ; 1346-4523
    DOI 10.1007/s10396-023-01343-6
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    Zs.B 2695: Show issues Location:
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    Zs.B 2695 -Engl.Ausg.-: Show issues Location:
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  4. Article: Ureterocele prolapse eliciting unusual patient behavior to control intermittent voiding.

    Nishio, Hidenori / Mizuno, Kentaro / Matsumoto, Daisuke / Yasui, Takahiro / Hayashi, Yutaro

    Urology case reports

    2022  Volume 46, Page(s) 102295

    Abstract: Ureterocele prolapse, an unusual but distinctive finding, may cause voiding difficulty. A 6-year-old male patient was referred to our hospital after his mother discovered that he tapped his lower abdomen when his urinary stream was interrupted during ... ...

    Abstract Ureterocele prolapse, an unusual but distinctive finding, may cause voiding difficulty. A 6-year-old male patient was referred to our hospital after his mother discovered that he tapped his lower abdomen when his urinary stream was interrupted during voiding. Voiding cystourethrography indicated a ureterocele prolapse causing the intermittency of voiding; therefore, transvesicoscopic ureteral reimplantation with ureterocelectomy was performed and the voiding consequently improved. However, this condition would not have been diagnosed had the unusual voiding behavior gone unnoticed. Therefore, diagnosing congenital bladder obstructions could be challenging if a patient adapts to a voiding difficulty.
    Language English
    Publishing date 2022-11-30
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2745459-9
    ISSN 2214-4420
    ISSN 2214-4420
    DOI 10.1016/j.eucr.2022.102295
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  5. Article ; Online: Editorial: Immunity and Inflammatory Response in Kidney Stone Disease.

    Thongboonkerd, Visith / Yasui, Takahiro / Khan, Saeed R

    Frontiers in immunology

    2021  Volume 12, Page(s) 795559

    MeSH term(s) Animals ; Calcium Oxalate/metabolism ; Humans ; Immunity ; Inflammation/immunology ; Kidney/metabolism ; Kidney/pathology ; Kidney Calculi/immunology ; Macrophages/immunology ; Transcriptome
    Chemical Substances Calcium Oxalate (2612HC57YE)
    Language English
    Publishing date 2021-11-01
    Publishing country Switzerland
    Document type Editorial ; Introductory Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2021.795559
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  6. Article: Conservative management of pubertal segmental testicular infarction associated with epididymitis.

    Nishio, Hidenori / Mizuno, Kentaro / Matsumoto, Daisuke / Nakane, Akihiro / Yasui, Takahiro / Hayashi, Yutaro

    Urology case reports

    2023  Volume 46, Page(s) 102324

    Abstract: Urgent scrotal exploration is performed for segmental testicular infarction (STI) because malignant testicular tumors cannot be ruled out even when STI is suspected on color Doppler ultrasound (US). This report describes the case of a 14-year-old boy who ...

    Abstract Urgent scrotal exploration is performed for segmental testicular infarction (STI) because malignant testicular tumors cannot be ruled out even when STI is suspected on color Doppler ultrasound (US). This report describes the case of a 14-year-old boy who was successfully diagnosed with STI associated with epididymitis using color Doppler US to avoid radical orchiectomy. To our knowledge, this is the first report of STI being diagnosed during puberty and managed using color Doppler US and contrast-enhanced magnetic resonance imaging-guided conservative treatment.
    Language English
    Publishing date 2023-01-11
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2745459-9
    ISSN 2214-4420
    ISSN 2214-4420
    DOI 10.1016/j.eucr.2023.102324
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  7. Article ; Online: Identification of active spermatogenesis using a multiphoton microscope.

    Takeda, Tomoki / Iwatsuki, Shoichiro / Nozaki, Satoshi / Okada, Atsushi / Mizuno, Kentaro / Umemoto, Yukihiro / Yasui, Takahiro

    Andrology

    2023  Volume 11, Issue 6, Page(s) 1147–1156

    Abstract: Background: The sperm retrieval rate of microdissection testicular sperm extraction varies from 25% to 60%. Therefore, it is necessary to establish objective selection criteria for identifying seminiferous tubules with spermatozoa.: Objectives: Our ... ...

    Abstract Background: The sperm retrieval rate of microdissection testicular sperm extraction varies from 25% to 60%. Therefore, it is necessary to establish objective selection criteria for identifying seminiferous tubules with spermatozoa.
    Objectives: Our aim was to develop a method for identifying spermatogenesis without sectioning testicular tissues.
    Materials and methods: Testicular tissues of 10-week-old normal rats were fixed with 4% paraformaldehyde. Fluorescent labeling of seminiferous tubule nuclei and F-actin was performed, and the specimens were observed without sectioning using a multiphoton microscope. Cryptorchid rats were used as a model lacking elongated spermatids. Multiphoton images were compared with images of normal seminiferous tubules. In addition, seminiferous tubules of 10-week-old normal rats were labeled by testicular interstitial injection of fluorescent probes and observed by a multiphoton microscope without fixation. Terminal deoxynucleotidyl transferase dUTP nick end labeling-stained images of normal and probe-injected testes were compared.
    Results: In fixed seminiferous tubules, elongated spermatids were identified. In addition, F-actin of apical ectoplasmic specialization was observed around elongated spermatids. Furthermore, spermatogenic stages were identified by an array of nuclei or F-actin. In cryptorchid testes, elongated spermatids and F-actin of the apical ectoplasmic specialization were not observed. In testes injected with fluorescent probes, F-actin of the apical ectoplasmic specialization was observed, and spermatogenic stages were identified without fixation. There was no significant difference in the number of terminal deoxynucleotidyl transferase dUTP nick end labeling-positive cells per seminiferous tubule between normal and probe-injected testes.
    Conclusions: Seminiferous epithelium could be observed without sectioning of tissues by fluorescent probes and a multiphoton microscope. Active spermatogenesis was observed by labeling F-actin with and without fixation. Moreover, the toxicity of fluorescent probes was limited. Our method has a potential for live imaging of testicular tissue.
    MeSH term(s) Male ; Rats ; Animals ; Actins ; DNA Nucleotidylexotransferase ; Fluorescent Dyes ; Semen ; Spermatogenesis ; Testis ; Spermatids ; Seminiferous Tubules
    Chemical Substances Actins ; DNA Nucleotidylexotransferase (EC 2.7.7.31) ; Fluorescent Dyes
    Language English
    Publishing date 2023-01-16
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2696108-8
    ISSN 2047-2927 ; 2047-2919
    ISSN (online) 2047-2927
    ISSN 2047-2919
    DOI 10.1111/andr.13379
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6983: Show issues Location:
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  8. Article ; Online: Combination of robot-assisted laparoscopic pyeloplasty for lower moiety ureteropelvic junction obstruction in a partial duplex system and percutaneous endoscopic surgery for renal calculi reusing the port for robotic pyeloplasty.

    Nishio, Hidenori / Mizuno, Kentaro / Matsumoto, Daisuke / Tozawa, Keiichi / Yasui, Takahiro / Hayashi, Yutaro

    IJU case reports

    2023  Volume 6, Issue 6, Page(s) 390–393

    Abstract: Introduction: Ureteropelvic junction obstruction is often associated with renal calculus formation. However, there is no report of using robot-assisted laparoscopic pyeloplasty combined with percutaneous endoscopic surgery for ureteropelvic junction ... ...

    Abstract Introduction: Ureteropelvic junction obstruction is often associated with renal calculus formation. However, there is no report of using robot-assisted laparoscopic pyeloplasty combined with percutaneous endoscopic surgery for ureteropelvic junction obstruction and renal calculi in a partial duplex system.
    Case presentation: A 19-year-old female patient with lower moiety ureteropelvic junction obstruction and renal calculi in a partial duplex system was referred to our hospital because of left lumbar pain, left acute pyelonephritis, and an increase in left renal calculi during follow-up at the referral hospital. To prevent the complication of percutaneous nephrolithotripsy following pyeloplasty, robot-assisted laparoscopic pyeloplasty combined with percutaneous endoscopic surgery was performed. Two years after surgery, the patient reported no left lumbar pain.
    Conclusion: The combination of robot-assisted laparoscopic pyeloplasty and percutaneous endoscopic surgery can be proposed as a safe and less-invasive treatment option for ureteropelvic junction obstruction and renal calculi in a partial duplex system.
    Language English
    Publishing date 2023-09-03
    Publishing country Australia
    Document type Case Reports
    ISSN 2577-171X
    ISSN (online) 2577-171X
    DOI 10.1002/iju5.12630
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Urodynamic effectiveness of a beta-3 adrenoreceptor agonist (vibegron) for a pediatric patient with anticholinergic-resistant neurogenic detrusor overactivity: a case report.

    Kato, Taiki / Mizuno, Kentaro / Nishio, Hidenori / Yasui, Takahiro / Hayashi, Yutaro

    Journal of medical case reports

    2021  Volume 15, Issue 1, Page(s) 86

    Abstract: Background: Myelomeningocele, which causes a neurogenic bladder, is usually treated with anticholinergics in children with neurogenic detrusor overactivity (NDO); however, anticholinergics cause side effects such as dry mouth, constipation, attention ... ...

    Abstract Background: Myelomeningocele, which causes a neurogenic bladder, is usually treated with anticholinergics in children with neurogenic detrusor overactivity (NDO); however, anticholinergics cause side effects such as dry mouth, constipation, attention deficit, and inadequate reduction in detrusor leak point pressure. Vibegron, a novel selective beta-3 adrenoreceptor agonist, is a well-established alternative to anticholinergics in adults with an overactive bladder. It remains unknown whether this agent can be used for pediatric patients. We report the case of a girl with anticholinergic-resistant NDO due to tethered cord syndrome after myelomeningocele repair, who was treated with vibegron.
    Case presentation: A 4-year-old Filipino girl had increased frequency of daytime urinary incontinence and foul-smelling urine since the age of 3. Clinical examination revealed constipation, and urinalysis revealed bacteriuria. Voiding cystourethrography revealed an enlarged and trabeculated bladder without vesicoureteral reflux. On the urodynamic study (UDS), she was found to have detrusor overactivity (DO) and low bladder compliance. She could not void and was diagnosed with overflow incontinence. Clean intermittent catheterization (CIC) and orally administered propiverine (0.8 mg/kg/day) were initiated, and urinary incontinence was resolved. She underwent a UDS annually; the UDS at 6 years of age still revealed DO and low bladder compliance in spite of receiving propiverine. The treatment was switched from propiverine to vibegron (1.4 mg/kg/day). On the UDS after a 5-week treatment schedule of vibegron, the DO disappeared and the bladder compliance improved. CIC and orally administered vibegron have been continued for 7 months so far, and she has had no urinary tract infection with no drug-related adverse events.
    Conclusions: Vibegron was effective and well tolerated in the treatment of a pediatric patient with NDO. Vibegron improved the urodynamic parameters for anticholinergic-resistant neurogenic bladder. This agent can be a beneficial and preferable alternative therapeutic agent to anticholinergics in patients with anticholinergic-resistant NDO.
    MeSH term(s) Adult ; Child ; Child, Preschool ; Cholinergic Antagonists ; Female ; Humans ; Pyrimidinones ; Pyrrolidines ; Treatment Outcome ; Urinary Bladder, Overactive/drug therapy ; Urodynamics
    Chemical Substances Cholinergic Antagonists ; N-(4-((5-(hydroxy(phenyl)methyl)pyrrolidin-2-yl)methyl)phenyl)-4-oxo-4,6,7,8-tetrahydropyrrolo(1,2-a)pyrimidine-6-carboxamide ; Pyrimidinones ; Pyrrolidines
    Language English
    Publishing date 2021-02-18
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 2269805-X
    ISSN 1752-1947 ; 1752-1947
    ISSN (online) 1752-1947
    ISSN 1752-1947
    DOI 10.1186/s13256-020-02564-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Macrophage Function in Calcium Oxalate Kidney Stone Formation: A Systematic Review of Literature.

    Taguchi, Kazumi / Okada, Atsushi / Unno, Rei / Hamamoto, Shuzo / Yasui, Takahiro

    Frontiers in immunology

    2021  Volume 12, Page(s) 673690

    Abstract: Background: The global prevalence and recurrence rate of kidney stones is very high. Recent studies of Randall plaques and urinary components : Methods: We systematically reviewed the literature during February 2021 according to the Preferred ... ...

    Abstract Background: The global prevalence and recurrence rate of kidney stones is very high. Recent studies of Randall plaques and urinary components
    Methods: We systematically reviewed the literature during February 2021 according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Articles investigating the relationship between macrophages and urolithiasis, particularly calcium oxalate (CaOx) stones, were extracted from PubMed, MEDLINE, Embase, and Scopus. Study subjects, languages, and publication dates were unrestricted. Two authors searched and screened the publications.
    Results: Although several studies have applied mixed modalities, we selected 10, 12, and seven (total, n = 29) of 380 articles that respectively described cultured cells, animal models, and human samples.The investigative trend has shifted to macrophage phenotypes and signaling pathways, including micro (m)-RNAs since the discovery of macrophage involvement in kidney stones in 1999. Earlier studies of mice-associated macrophages with the acceleration and suppression of renal crystal formation. Later studies found that pro-inflammatory M1- and anti-inflammatory M2-macrophages are involved. Studies of human-derived and other macrophages
    Conclusions: This systematic review provides an update regarding the current status of macrophage involvement in CaOx nephrolithiasis. Targeting M2-like macrophage function might offer a therapeutic strategy with which to prevent stones
    MeSH term(s) Animals ; Calcium Oxalate ; Humans ; Kidney Calculi/immunology ; Kidney Calculi/metabolism ; Macrophages/immunology ; Macrophages/metabolism ; Nephrolithiasis/immunology ; Nephrolithiasis/metabolism
    Chemical Substances Calcium Oxalate (2612HC57YE)
    Language English
    Publishing date 2021-05-24
    Publishing country Switzerland
    Document type Research Support, Non-U.S. Gov't ; Systematic Review
    ZDB-ID 2606827-8
    ISSN 1664-3224 ; 1664-3224
    ISSN (online) 1664-3224
    ISSN 1664-3224
    DOI 10.3389/fimmu.2021.673690
    Database MEDical Literature Analysis and Retrieval System OnLINE

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