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  1. Article: Optimal lymph node dissection for T3-T4 lower rectal cancer, the so-called "high risk" group: the Japanese experience.

    Yasuno, M

    Il Giornale di chirurgia

    2009  Volume 30, Issue 10, Page(s) 393–399

    MeSH term(s) Female ; Humans ; Japan ; Lymph Node Excision ; Lymphatic Metastasis ; Male ; Middle Aged ; Neoplasm Staging ; Rectal Neoplasms/pathology ; Rectal Neoplasms/surgery ; Risk Factors
    Language English
    Publishing date 2009-10
    Publishing country Italy
    Document type Editorial
    ZDB-ID 605974-0
    ISSN 1971-145X ; 0391-9005
    ISSN (online) 1971-145X
    ISSN 0391-9005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2760: Show issues Location:
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  2. Article: [Combination of surgery and chemotherapy in the treatment of patients with colorectal liver metastases; conversion therapy].

    Yasuno, Masamichi

    Nihon rinsho. Japanese journal of clinical medicine

    2011  Volume 69 Suppl 3, Page(s) 446–453

    MeSH term(s) Antineoplastic Agents/administration & dosage ; Colorectal Neoplasms/pathology ; Hepatectomy ; Humans ; Liver Neoplasms/secondary ; Liver Neoplasms/therapy ; Neoadjuvant Therapy
    Chemical Substances Antineoplastic Agents
    Language Japanese
    Publishing date 2011-04
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 390903-7
    ISSN 0047-1852
    ISSN 0047-1852
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: Zooplankton community structure driven by vertebrate and invertebrate predators.

    Hanazato, Takayuki / Yasuno, Masayuki

    Oecologia

    2017  Volume 81, Issue 4, Page(s) 450–458

    Abstract: A zooplankton community was established in outdoor experimental ponds, into which a vertebrate predator (topmouth gudgeon: Pseudorasbora parva) and/or an invertebrate predator (phantom midge larva: Chaoborus flavicans) were introduced and their predation ...

    Abstract A zooplankton community was established in outdoor experimental ponds, into which a vertebrate predator (topmouth gudgeon: Pseudorasbora parva) and/or an invertebrate predator (phantom midge larva: Chaoborus flavicans) were introduced and their predation effects on the zooplankton community structure were evaluated. In the ponds which had Chaoborus but not fish, small- and medium-sized cladocerans and calanoid copepods were eliminated while rotifers became abundant. A large-sized cladoceran Daphnia longispina, whose juveniles had high helmets and long tailspines as anti-predator devices, escaped from Chaoborus predation and increased. In the ponds which had fish but not Chaoborus, the large-sized Daphnia was selectively predated by the fish while small-and medium-sized cladocerans and calanoid copepods predominated. In the ponds containing both Chaoborus and fish, the fish reduced the late instar larvae (III and IV) of Chaoborus but increased the early instar larvae (I and II). Small- and large-sized cladocerans were scarcely found. The former might have been eliminated by predation of the early instar larvae of Chaoborus, while the latter was probably predated by fish. Consequently, the medium-sized cladocerans, which may have succeeded in escaping from both types of predator, appeared abundantly. The results suggest that various combinations of vertebrate and invertebrate predators are able to drive various kinds of zooplankton community structure.
    Language English
    Publishing date 2017-03-17
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 123369-5
    ISSN 1432-1939 ; 0029-8549
    ISSN (online) 1432-1939
    ISSN 0029-8549
    DOI 10.1007/BF00378951
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  4. Article ; Online: Effectiveness of Wound-Edge Protectors for Preventing Surgical Site Infections after Open Surgery for Colorectal Disease: A Prospective Cohort Study with Two Parallel Study Groups.

    Kobayashi, Hirotoshi / Uetake, Hiroyuki / Yasuno, Masamichi / Sugihara, Kenichi

    Digestive surgery

    2018  Volume 36, Issue 1, Page(s) 83–88

    Abstract: Background: Standard procedures to reduce the surgical site infection (SSI) rate after colorectal surgery have not been established. A prospective cohort study with 2 parallel study groups was performed to clarify the SSI rate after open surgery with ... ...

    Abstract Background: Standard procedures to reduce the surgical site infection (SSI) rate after colorectal surgery have not been established. A prospective cohort study with 2 parallel study groups was performed to clarify the SSI rate after open surgery with and without a wound-edge protector (WEP) for colorectal disease.
    Methods: A total of 102 patients who underwent elective open surgery for colorectal disease between October 2012 and August 2014 were randomly assigned to a WEP group and a WEP (-) group. The primary endpoint was the SSI rate in both groups.
    Results: Fifty-one patients were assigned to the WEP group and 51 to the WEP (-) group. Two patients were excluded from this study. The rate of SSI with and without a WEP was 16 and 36% respectively (p = 0.021). Older age (p = 0.0073) and no WEP (p = 0.021) were risk factors for SSI after open surgery for colorectal diseases on univariate analysis. On multivariate analysis, both older age (p = 0.016) and no WEP (p = 0.012) were independent risk factors for SSI.
    Conclusion: The present randomized, phase II trial found an SSI rate of 16% with use of a WEP. The SSI rate was lower in the WEP group than in the WEP (-) group. A WEP may reduce the SSI rate after open surgery for colorectal disease in Japanese patients.
    MeSH term(s) Age Factors ; Aged ; Colonic Neoplasms/surgery ; Digestive System Surgical Procedures/adverse effects ; Digestive System Surgical Procedures/instrumentation ; Elective Surgical Procedures/adverse effects ; Elective Surgical Procedures/instrumentation ; Female ; Humans ; Male ; Prospective Studies ; Rectal Neoplasms/surgery ; Risk Factors ; Surgical Wound Infection/prevention & control
    Language English
    Publishing date 2018-04-26
    Publishing country Switzerland
    Document type Clinical Trial, Phase II ; Journal Article ; Randomized Controlled Trial
    ZDB-ID 605888-7
    ISSN 1421-9883 ; 0253-4886
    ISSN (online) 1421-9883
    ISSN 0253-4886
    DOI 10.1159/000488214
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  5. Article ; Online: A metastasis-associated microRNA-based liquid biopsy signature for risk-stratification in colorectal cancer: a multicenter cohort study.

    Matsuyama, Takatoshi / Toiyama, Yuji / Ishikawa, Toshiaki / Okugawa, Yoshinaga / Yasuno, Masamichi / Maurel, Joan / Kinugasa, Yusuke / Uetake, Hiroyuki / Goel, Ajay

    Clinical and translational medicine

    2022  Volume 12, Issue 12, Page(s) e998

    MeSH term(s) Humans ; MicroRNAs/genetics ; Liquid Biopsy ; Colorectal Neoplasms/diagnosis ; Colorectal Neoplasms/genetics ; Colorectal Neoplasms/pathology ; Cohort Studies
    Chemical Substances MicroRNAs
    Language English
    Publishing date 2022-12-13
    Publishing country United States
    Document type Multicenter Study ; Letter ; Research Support, N.I.H., Extramural
    ZDB-ID 2697013-2
    ISSN 2001-1326 ; 2001-1326
    ISSN (online) 2001-1326
    ISSN 2001-1326
    DOI 10.1002/ctm2.998
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Simultaneous Hydrostatic and Compressive Loading System for Mimicking the Mechanical Environment of Living Cartilage Tissue.

    Chang, Minki / Takahashi, Yosuke / Miyahira, Kyosuke / Omuro, Yuma / Montagne, Kevin / Yamada, Ryusei / Gondo, Junki / Kambe, Yu / Yasuno, Masashi / Masumoto, Noriyasu / Ushida, Takashi / Furukawa, Katsuko S

    Micromachines

    2023  Volume 14, Issue 8

    Abstract: In vivo, articular cartilage tissue is surrounded by a cartilage membrane, and hydrostatic pressure (HP) and compressive strain increase simultaneously with the compressive stress. However, it has been impossible to investigate the effects of ... ...

    Abstract In vivo, articular cartilage tissue is surrounded by a cartilage membrane, and hydrostatic pressure (HP) and compressive strain increase simultaneously with the compressive stress. However, it has been impossible to investigate the effects of simultaneous loading in vitro. In this study, a bioreactor capable of applying compressive stress under HP was developed to reproduce ex vivo the same physical loading environment found in cartilage. First, a HP stimulation unit was constructed to apply a cyclic HP pressure-resistant chamber by controlling a pump and valve. A compression-loading mechanism that can apply compressive stress using an electromagnetic force was implemented in the chamber. The synchronization between the compression and HP units was evaluated, and the stimulation parameters were quantitatively evaluated. Physiological HP and compressive strain were applied to the chondrocytes encapsulated in alginate and gelatin gels after applying high HP at 25 MPa, which induced damage to the chondrocytes. It was found that compressive stimulation increased the expression of genes related to osteoarthritis. Furthermore, the simultaneous application of compressive strain and HP, which is similar to the physiological environment in cartilage, had an inhibitory effect on the expression of genes related to osteoarthritis. HP alone also suppressed the expression of osteoarthritis-related genes. Therefore, the simultaneous hydrostatic and compressive stress-loading device developed to simulate the mechanical environment in vivo may be an important tool for elucidating the mechanisms of disease onset and homeostasis in cartilage.
    Language English
    Publishing date 2023-08-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2620864-7
    ISSN 2072-666X
    ISSN 2072-666X
    DOI 10.3390/mi14081632
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  7. Article: Management of patients with asymptomatic colorectal cancer and synchronous irresectable metastases.

    Ishikawa, Toshiaki / Yasuno, Masamichi / Uetake, Hiroyuki

    Nihon Shokakibyo Gakkai zasshi The Japanese journal of gastro-enterology

    2017  Volume 114, Issue 7, Page(s) 1201–1208

    MeSH term(s) Clinical Trials as Topic ; Colorectal Neoplasms/diagnosis ; Colorectal Neoplasms/pathology ; Colorectal Neoplasms/therapy ; Humans ; Neoplasm Metastasis ; Neoplasm Staging ; Quality of Life ; Risk Factors
    Language Japanese
    Publishing date 2017-07-05
    Publishing country Japan
    Document type Journal Article ; Review
    ZDB-ID 708695-7
    ISSN 1349-7693 ; 0446-6586
    ISSN (online) 1349-7693
    ISSN 0446-6586
    DOI 10.11405/nisshoshi.114.1201
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    In stock of ZB MED Cologne/Königswinter

    Ui V Zs.34: Show issues Location:
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  8. Article: Effectiveness of Wound-Edge Protectors for Preventing Surgical Site Infections after Open Surgery for Colorectal Disease: A Prospective Cohort Study with Two Parallel Study Groups

    Kobayashi, Hirotoshi / Uetake, Hiroyuki / Yasuno, Masamichi / Sugihara, Kenichi

    Digestive Surgery

    2018  Volume 36, Issue 1, Page(s) 83–88

    Abstract: Background: Standard procedures to reduce the surgical site infection (SSI) rate after colorectal surgery have not been established. A prospective cohort study with 2 parallel study groups was performed to clarify the SSI rate after open surgery with and ...

    Institution Department of Surgery, Tokyo Metropolitan Hiroo Hospital, Tokyo, Japan
    Department of Surgical Oncology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Abstract Background: Standard procedures to reduce the surgical site infection (SSI) rate after colorectal surgery have not been established. A prospective cohort study with 2 parallel study groups was performed to clarify the SSI rate after open surgery with and without a wound-edge protector (WEP) for colorectal disease. Methods: A total of 102 patients who underwent elective open surgery for colorectal disease between October 2012 and August 2014 were randomly assigned to a WEP group and a WEP (–) group. The primary endpoint was the SSI rate in both groups. Results: Fifty-one patients were assigned to the WEP group and 51 to the WEP (–) group. Two patients were excluded from this study. The rate of SSI with and without a WEP was 16 and 36% respectively (p = 0.021). Older age (p = 0.0073) and no WEP (p = 0.021) were risk factors for SSI after open surgery for colorectal diseases on univariate analysis. On multivariate analysis, both older age (p = 0.016) and no WEP (p = 0.012) were independent risk factors for SSI. Conclusion: The present randomized, phase II trial found an SSI rate of 16% with use of a WEP. The SSI rate was lower in the WEP group than in the WEP (–) group. A WEP may reduce the SSI rate after open surgery for colorectal disease in Japanese patients.
    Keywords Wound-edge protector ; Surgical site infection ; Colorectal surgery
    Language English
    Publishing date 2018-04-26
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Original Paper
    ZDB-ID 605888-7
    ISSN 1421-9883 ; 0253-4886
    ISSN (online) 1421-9883
    ISSN 0253-4886
    DOI 10.1159/000488214
    Database Karger publisher's database

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  9. Article: Effects of carbaryl on the spring zooplankton communities in ponds.

    Hanazato, T / Yasuno, M

    Environmental pollution (Barking, Essex : 1987)

    2004  Volume 56, Issue 1, Page(s) 1–10

    Abstract: A carbamate insecticide, carbaryl, was applied in spring to concrete ponds to study its effects on zooplankton communities. The population density of Cladocera (Daphnia spp.) was nearly constant before application of the chemical. Carbaryl at 1 ppm ... ...

    Abstract A carbamate insecticide, carbaryl, was applied in spring to concrete ponds to study its effects on zooplankton communities. The population density of Cladocera (Daphnia spp.) was nearly constant before application of the chemical. Carbaryl at 1 ppm killed all zooplankton species, including Chaoborus larvae. After treatment, cladocerans never recovered to their previous level. The relatively rapid recovery of a predator, Chaoborus, seemed to interfere with recovery of the cladoceran populations. The lower water temperature occurring in spring was thought to favour the former because of its influence on growth rates.
    Language English
    Publishing date 2004-05-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0269-7491 ; 0013-9327
    ISSN (online) 1873-6424
    ISSN 0269-7491 ; 0013-9327
    DOI 10.1016/0269-7491(89)90116-4
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    Zs.A 2599: Show issues Location:
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  10. Article: Effects of a carbamate insecticide, carbaryl, on the summer phyto- and zooplankton communities in ponds.

    Hanazato, T / Yasuno, M

    Environmental pollution (Barking, Essex : 1987)

    2004  Volume 48, Issue 2, Page(s) 145–159

    Abstract: A carbamate insecticide, carbaryl (1-naphthyl-N-methylcarbamate), was applied in concrete ponds and the effects on plankton communities were studied. In a control pond, Cladocera declined following the increase in the density of inedible algae after a ... ...

    Abstract A carbamate insecticide, carbaryl (1-naphthyl-N-methylcarbamate), was applied in concrete ponds and the effects on plankton communities were studied. In a control pond, Cladocera declined following the increase in the density of inedible algae after a cladoceran peak. Once the density of Cladocera became low, Chaoborus larvae suppressed the increase of Cladocera and consequently supported the rotifer dominance in the zooplankton community by their selective predation on cladocerans. In a treated pond, the plankton community and its succession were similar to those in the control pond until the chemical application. 1 ppm of carbaryl killed all zooplankton and Chaoborus larvae. Cladocera reappeared soon and increased rapidly due to the absence of Chaoborus larvae. Consequently, rotifer populations were suppressed. Thus, the chemical application altered the dominance of rotifers to that of cladocerans. The same phenomenon was observed again after the second chemical application 12 days after. Although apparent direct effects of the chemical application on phytoplankton were not found, the phytoplankton community structure changed following the changes in the zooplankton density.
    Language English
    Publishing date 2004-05-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 280652-6
    ISSN 1873-6424 ; 0269-7491 ; 0013-9327
    ISSN (online) 1873-6424
    ISSN 0269-7491 ; 0013-9327
    DOI 10.1016/0269-7491(87)90093-5
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