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Article ; Online: SCALING: plug-n-play device-free indoor tracking.

Xie, Zongxing / Ye, Fan

2024 Volume 14, Issue 1, Page(s) 2913

Abstract: 24/7 continuous recording of in-home daily trajectories is informative for health status assessment (e.g., monitoring Alzheimer's, dementia based on behavior patterns). Indoor device-free localization/tracking are ideal because no user efforts on wearing ...

Abstract	24/7 continuous recording of in-home daily trajectories is informative for health status assessment (e.g., monitoring Alzheimer's, dementia based on behavior patterns). Indoor device-free localization/tracking are ideal because no user efforts on wearing devices are needed. However, prior work mainly focused on improving the localization accuracy. They relied on well-calibrated sensor placements, which require hours of intensive manual setup and respective expertise, feasible only at small scale and by mostly researchers themselves. Scaling the deployments to tens or hundreds of real homes, however, would incur prohibitive manual efforts, and become infeasible for layman users. We present SCALING, a plug-and-play indoor trajectory monitoring system that layman users can easily set up by walking a one-minute loop trajectory after placing radar nodes on walls. It uses a self calibrating algorithm that estimates sensor locations through their distance measurements to the person walking the trajectory, a trivial effort without taxing layman users physically or cognitively. We evaluate SCALING via simulations and two testbeds (in lab and home configurations of sizes 3[Formula: see text]6 sq m and 4.5[Formula: see text]8.5 sq m). Experimental results demonstrate that SCALING outperformed the baseline using the approximate multidimensional scaling (MDS, the most relevant method in the context of self calibration) by 3.5 m/1.6 m in 80-percentile error of self calibration and tracking, respectively. Notably, only 1% degradation in performance has been observed with SCALING compared to the classical multilateration with known sensor locations (anchors), which costs hours of intensive calibrating effort. In addition, we conduct Monte Carlo experiments to numerically analyze the impact of sensor placements and develop practical guidelines for deployment in real life scenarios.
Language	English
Publishing date	2024-02-05
Publishing country	England
Document type	Journal Article
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-024-53524-z
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Integrating Health and Care for Older People in China: What Has Been Accomplished? What is Next?

Hu, Linlin / Glavin, Ye-Fan Wang

International journal of integrated care

2023 Volume 23, Issue 1, Page(s) 16

Language	English
Publishing date	2023-03-23
Publishing country	England
Document type	Editorial
ZDB-ID	2119289-3
ISSN	1568-4156
ISSN	1568-4156
DOI	10.5334/ijic.7598
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Transfer learning from rating prediction to Top-k recommendation.

Ye, Fan / Lu, Xiaobo / Li, Hongwei / Chen, Zhenyu

PloS one

2024 Volume 19, Issue 3, Page(s) e0300240

Abstract: Recommender system has made great strides in two major research fields, rating prediction and Top-k recommendation. In essence, rating prediction is a regression task, which aims to predict users scores on other items, while Top-k is a classification ... ...

Abstract	Recommender system has made great strides in two major research fields, rating prediction and Top-k recommendation. In essence, rating prediction is a regression task, which aims to predict users scores on other items, while Top-k is a classification task selecting the items that users have the most potential to interact with. Both characterize users and items, but the optimization of parameters varies widely for their respective tasks. Inspired by the idea of transfer learning, we consider extracting the information learned from rating prediction models for serving for Top-k tasks. To this end, we propose a universal transfer model for recommender systems. The transfer model consists of two sub-components: quadruple-based Bayesian Converter (BC) and Prediction-based Multi-Layer Perceptron (PMLP). As the main part, BC is responsible for transforming the feature vectors extracted from the rating prediction model. Meanwhile, PMLP extracts the prediction ratings, constructs the prediction rating matrix, and uses multi-layer perceptron to enhance the final performance. On four benchmark datasets, we use the information extracted from the singular value decomposition plus plus (SVD++) model to demonstrate the effectiveness of BC-PMLP, comparing to classical and state-of-the-art baselines. We also conduct extra experiments to verify the utility of BC, and performance within different parameter values.
MeSH term(s)	Algorithms ; Bayes Theorem ; Neural Networks, Computer ; Machine Learning
Language	English
Publishing date	2024-03-28
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0300240
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Article ; Online: Integrating Health and Care for Older People in China

Linlin Hu / Ye-Fan Wang Glavin

International Journal of Integrated Care, Vol 23, Pp 16-

What Has Been Accomplished? What is Next?

2023 Volume 16

Keywords	integration ; health ; care ; older people ; china ; Medicine (General) ; R5-920
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	Ubiquity Press
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Morphological Effects of Au Nanoparticles on Electrochemical Sensing Platforms for Nitrite Detection

Ruiqin Feng / Ye Fan / Yun Fang / Yongmei Xia

Molecules, Vol 28, Iss 4934, p

2023 Volume 4934

Abstract: Au nanoparticles were synthesized in a soft template of pseudo-polyanions composed of polyvinylpyrrolidone (PVP) and sodium dodecyl sulfate (SDS) by the in situ reduction of chloroauric acid (HAuCl 4 ) with PVP. The particle sizes and morphologies of the ...

Abstract	Au nanoparticles were synthesized in a soft template of pseudo-polyanions composed of polyvinylpyrrolidone (PVP) and sodium dodecyl sulfate (SDS) by the in situ reduction of chloroauric acid (HAuCl 4 ) with PVP. The particle sizes and morphologies of the Au nanoparticles were regulated with concentrations of PVP or SDS at room temperature. Distinguished from the Au nanoparticles with various shapes, Au nanoflowers (AuNFs) with rich protrusion on the surface were obtained at the low final concentration of SDS and PVP. The typical AuNF synthesized in the PVP (50 g·L −1 )–SDS (5 mmol·L −1 )–HAuCl 4 (0.25 mmol·L −1 ) solution exhibited a face-centered cubic structure dominated by a {111} crystal plane with an average equivalent particle size of 197 nm and an average protrusion height of 19 nm. Au nanoparticles with four different shapes, nanodendritic, nanoflower, 2D nanoflower, and nanoplate, were synthesized and used to modify the bare glassy carbon electrode (GCE) to obtain Au/GCEs, which were assigned as AuND/GCE, AuNF/GCE, 2D-AuNF/GCE, and AuNP/GCE, respectively. Electrochemical sensing platforms for nitrite detection were constructed by these Au/GCEs, which presented different detection sensitivity for nitrites. The results of cyclic voltammetry (CV) demonstrated that the AuNF/GCE exhibited the best detection sensitivity for nitrites, and the surface area of the AuNF/GCE was 1.838 times of the bare GCE, providing a linear c (NO 2 − ) detection range of 0.01–5.00 µmol·L −1 with a limit of detection of 0.01 µmol·L −1 . In addition, the AuNF/GCE exhibited good reproducibility, stability, and high anti-interference, providing potential for application in electrochemical sensing platforms.
Keywords	Au nanoparticle ; Au/GCE ; nitrite ; cyclic voltammetry ; polyvinylpyrrolidone ; sodium lauryl sulfate ; Organic chemistry ; QD241-441
Subject code	333
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Hofstadter butterfly and topological edge states in a quasiperiodic photonic crystal cavity array.

Ye, Fan / Sun, Xiankai

Optics express

2022 Volume 30, Issue 15, Page(s) 26620–26627

Abstract: Quasiperiodic structures with additional synthetic degrees of freedom have recently been recognized as a promising way for investigating high-dimensional topological phases with lower physical dimensions. Here, we investigated the well-known Harper-Aubry- ...

Abstract	Quasiperiodic structures with additional synthetic degrees of freedom have recently been recognized as a promising way for investigating high-dimensional topological phases with lower physical dimensions. Here, we investigated the well-known Harper-Aubry-André model on an integrated photonic platform by proposing a new design of a quasiperiodic photonic crystal (PhC) cavity array. This array is composed of closely coupled H1 PhC cavities with their cavity lengths being periodically modulated in the real space. The frequency spectrum of the structure shows the main features of the Hofstadter butterfly, which is one of the most important phenomena in the Harper-Aubry-André model. By varying the modulation phase, this structure exhibits nontrivial topology, which supports strongly localized topological edge states. These results have shown that quasiperiodic PhC cavity arrays can serve as the testbed for studying topological phases and new topological phenomena on an integrated platform.
Language	English
Publishing date	2022-10-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	1491859-6
ISSN	1094-4087 ; 1094-4087
ISSN (online)	1094-4087
ISSN	1094-4087
DOI	10.1364/OE.453985
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Article ; Online: Origin, evolution, and diversification of inositol 1,4,5-trisphosphate 3-kinases in plants and animals.

Xiong, Tao / Zhang, Zaibao / Fan, Tianyu / Ye, Fan / Ye, Ziyi

BMC genomics

2024 Volume 25, Issue 1, Page(s) 350

Abstract: Background: In Eukaryotes, inositol polyphosphates (InsPs) represent a large family of secondary messengers and play crucial roes in various cellular processes. InsPs are synthesized through a series of pohophorylation reactions catalyzed by various ... ...

Abstract	Background: In Eukaryotes, inositol polyphosphates (InsPs) represent a large family of secondary messengers and play crucial roes in various cellular processes. InsPs are synthesized through a series of pohophorylation reactions catalyzed by various InsP kinases in a sequential manner. Inositol 1,4,5-trisphosphate 3-kinase (IP3 3-kinase/IP3K), one member of InsP kinase, plays important regulation roles in InsPs metabolism by specifically phosphorylating inositol 1,4,5-trisphosphate (IP3) to inositol 1,3,4,5-tetrakisphosphate (IP4) in animal cells. IP3Ks were widespread in fungi, plants and animals. However, its evolutionary history and patterns have not been examined systematically. Results: A total of 104 and 31 IP3K orthologues were identified across 57 plant genomes and 13 animal genomes, respectively. Phylogenetic analyses indicate that IP3K originated in the common ancestor before the divergence of fungi, plants and animals. In most plants and animals, IP3K maintained low-copy numbers suggesting functional conservation during plant and animal evolution. In Brassicaceae and vertebrate, IP3K underwent one and two duplication events, respectively, resulting in multiple gene copies. Whole-genome duplication (WGD) was the main mechanism for IP3K duplications, and the IP3K duplicates have experienced functional divergence. Finally, a hypothetical evolutionary model for the IP3K proteins is proposed based on phylogenetic theory. Conclusion: Our study reveals the evolutionary history of IP3K proteins and guides the future functions of animal, plant, and fungal IP3K proteins.
MeSH term(s)	Animals ; Inositol 1,4,5-Trisphosphate/metabolism ; Phosphotransferases (Alcohol Group Acceptor)/genetics ; Phylogeny ; Plants/genetics ; Plants/metabolism ; Evolution, Molecular
Chemical Substances	Inositol 1,4,5-Trisphosphate (85166-31-0) ; Phosphotransferases (Alcohol Group Acceptor) (EC 2.7.1.-)
Language	English
Publishing date	2024-04-08
Publishing country	England
Document type	Journal Article
ZDB-ID	2041499-7
ISSN	1471-2164 ; 1471-2164
ISSN (online)	1471-2164
ISSN	1471-2164
DOI	10.1186/s12864-024-10257-7
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Article ; Online: Kinematic and Joint Compliance Modeling Method to Improve Position Accuracy of a Robotic Vision System.

Ye, Fan / Jia, Guangpeng / Wang, Yukun / Chen, Xiaobo / Xi, Juntong

Sensors (Basel, Switzerland)

2024 Volume 24, Issue 8

Abstract: In the field of robotic automation, achieving high position accuracy in robotic vision systems (RVSs) is a pivotal challenge that directly impacts the efficiency and effectiveness of industrial applications. This study introduces a comprehensive modeling ...

Abstract	In the field of robotic automation, achieving high position accuracy in robotic vision systems (RVSs) is a pivotal challenge that directly impacts the efficiency and effectiveness of industrial applications. This study introduces a comprehensive modeling approach that integrates kinematic and joint compliance factors to significantly enhance the position accuracy of a system. In the first place, we develop a unified kinematic model that effectively reduces the complexity and error accumulation associated with the calibration of robotic systems. At the heart of our approach is the formulation of a joint compliance model that meticulously accounts for the intricacies of the joint connector, the external load, and the self-weight of robotic links. By employing a novel 3D rotary laser sensor for precise error measurement and model calibration, our method offers a streamlined and efficient solution for the accurate integration of vision systems into robotic operations. The efficacy of our proposed models is validated through experiments conducted on a FANUC LR Mate 200iD robot, showcasing notable improvements in the position accuracy of robotic vision system. Our findings contribute a framework for the calibration and error compensation of RVS, holding significant potential for advancements in automated tasks requiring high precision.
Language	English
Publishing date	2024-04-16
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2052857-7
ISSN	1424-8220 ; 1424-8220
ISSN (online)	1424-8220
ISSN	1424-8220
DOI	10.3390/s24082559
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Article ; Online: Insight into the Antibiotic Resistance of Bacteria Isolated from Popular Aquatic Products Collected in Zhejiang, China.

Wu, Jiajia / Ye, Fan / Qu, Jiong / Dai, Zhiyuan

Polish journal of microbiology

2023 Volume 72, Issue 1, Page(s) 61–67

Abstract: The present study was aimed to obtain a close insight into the distribution and diversity of antibiotic-resistant bacteria (ARB) and antibiotic-resistance genes (ARGs) among the aquatic products collected in Zhejiang, China. A total of 136 presumptive ... ...

Abstract	The present study was aimed to obtain a close insight into the distribution and diversity of antibiotic-resistant bacteria (ARB) and antibiotic-resistance genes (ARGs) among the aquatic products collected in Zhejiang, China. A total of 136 presumptive ARB picked up from six aquatic samples were classified into 22 genera and 49 species based on the 16S rDNA sequencing.
MeSH term(s)	Humans ; Genes, Bacterial ; Angiotensin Receptor Antagonists ; Angiotensin-Converting Enzyme Inhibitors ; Drug Resistance, Microbial/genetics ; Aeromonas/genetics ; Anti-Bacterial Agents/pharmacology
Chemical Substances	Angiotensin Receptor Antagonists ; Angiotensin-Converting Enzyme Inhibitors ; Anti-Bacterial Agents
Language	English
Publishing date	2023-03-24
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2234080-4
ISSN	2544-4646 ; 1733-1331
ISSN (online)	2544-4646
ISSN	1733-1331
DOI	10.33073/pjm-2023-010
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Article ; Online: Circ_0006667 contributes to high glucose-induced retinal pigment epithelial cell dysfunction by mediating miR-7-5p/TGFA axis in diabetic retinopathy.

Chen, Liling / Li, Ting / Ye, Fan

International ophthalmology

2023 Volume 43, Issue 7, Page(s) 2383–2396

Abstract: Background: Diabetic retinopathy (DR) is a common complication of diabetes mellitus and it can lead to visual impairment and blindness. The loss of retinal pigment epithelial (RPE) cells is associated with the etiology of DR. Moreover, dysregulated ... ...

Abstract	Background: Diabetic retinopathy (DR) is a common complication of diabetes mellitus and it can lead to visual impairment and blindness. The loss of retinal pigment epithelial (RPE) cells is associated with the etiology of DR. Moreover, dysregulated circular RNAs (circRNAs) are implicated in DR progression. Therefore, this project aims to explore the role and potential mechanism of circ_0006667 in DR. Methods: RPE cells (ARPE-19) were stimulated with high glucose (33 mM; HG group) for 24 h to establish the DR cell model. Circ_0006667, microRNA-7-5p (miR-7-5p), and transforming growth factor alpha (TGFA) expression was determined by reverse transcription-quantitative polymerase chain reaction (RT-qPCR). Cell viability, proliferation, and apoptosis were analyzed by 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), 5-ethynyl-2'-deoxyuridine (EdU), and flow cytometry. CyclinD1, Cleaved-caspase-3, and TGFA protein levels were detected using western blot. Using Circinteractome and starBase analysis, the binding miR-7-5p and circ_0006667 or TGFA was predicted, and then validated using dual-luciferase reporter and RNA Immunoprecipitation (RIP). Results: Circ_0006667 expression was up-regulated in DR patients and HG-induced ARPE-19 cells. HG stimulation suppressed ARPE-19 cell proliferation and promoted cell apoptosis and inflammation, which were alleviated via circ_0006667 silence. Circ_0006667 acted as a molecular sponge for miR-7-5p, and circ_0006667 absence-mediated protective effects in HG-induced ARPE-19 cells were largely overturned by the interference of miR-7-5p. miR-7-5p directly targeted TGFA, and miR-7-5p overexpression protected ARPE-19 cells from HG-induced dysfunction largely by down-regulating TGFA. Circ_0006667 can up-regulate the expression of TGFA by sponging miR-7-5p in ARPE-19 cells. Conclusion: Circ_0006667 silencing protected ARPE-19 cells from HG-induced dysfunction by mediating miR-7-5p/TGFA axis.
MeSH term(s)	Humans ; Diabetic Retinopathy/genetics ; Transforming Growth Factor alpha ; MicroRNAs/genetics ; Cell Proliferation ; Epithelial Cells ; Retinal Pigments ; Glucose ; Diabetes Mellitus
Chemical Substances	Transforming Growth Factor alpha ; MicroRNAs ; Retinal Pigments ; Glucose (IY9XDZ35W2) ; TGFA protein, human ; MIRN7 microRNA, human
Language	English
Publishing date	2023-01-30
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	800087-6
ISSN	1573-2630 ; 0165-5701
ISSN (online)	1573-2630
ISSN	0165-5701
DOI	10.1007/s10792-023-02636-y
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