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  1. Article ; Online: Abstracts of randomized controlled trials in pediatric dentistry: reporting quality and spin.

    Guo, Feiyang / Ye, Wengwanyue / Qin, Danchen / Fang, Xiaolin / Hua, Fang / He, Hong

    BMC medical research methodology

    2023  Volume 23, Issue 1, Page(s) 263

    Abstract: Background: Abstracts provide readers a concise and readily accessible information of the trials. However, poor reporting quality and spin (misrepresentation of research findings) can lead to an overestimation in trial validity. This methodological ... ...

    Abstract Background: Abstracts provide readers a concise and readily accessible information of the trials. However, poor reporting quality and spin (misrepresentation of research findings) can lead to an overestimation in trial validity. This methodological study aimed to assess the reporting quality and spin among randomized controlled trial (RCT) abstracts in pediatric dentistry.
    Methods: We hand-searched RCTs in five leading pediatric dental journals between 2015 and 2021. Reporting quality in each abstract was assessed using the original 16-item CONSORT for abstracts checklist. Linear regression analyses were performed to identify factors associated with reporting quality. We evaluated the presence and characteristics of spin only in abstracts of parallel-group RCTs with nonsignificant primary outcomes according to pre-determined spin strategies.
    Results: One hundred eighty-two abstracts were included in reporting quality evaluation. The mean overall quality score was 4.57 (SD, 0.103; 95% CI, 4.36-4.77; score range, 1-10). Only interventions, objective, and conclusions were adequately reported. Use of flow diagram (P < 0.001) was the only significant factor of higher reporting quality. Of the 51 RCT abstracts included for spin analysis, spin was identified in 40 abstracts (78.4%), among which 23 abstracts (45.1%) had spin in the Results section and 39 in the Conclusions Sect. (76.5%).
    Conclusions: The reporting quality of RCT abstracts in pediatric dentistry is suboptimal and the prevalence of spin is high. Joint efforts are needed to improve reporting quality and minimize spin.
    MeSH term(s) Humans ; Child ; Pediatric Dentistry ; Randomized Controlled Trials as Topic ; Checklist ; Regression Analysis
    Language English
    Publishing date 2023-11-10
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2041362-2
    ISSN 1471-2288 ; 1471-2288
    ISSN (online) 1471-2288
    ISSN 1471-2288
    DOI 10.1186/s12874-023-02085-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Using 3D Medical Modeling to Evaluate the Accuracy of Single-Photon Emission Computed Tomography (SPECT) Bone Scintigraphy in Diagnosing Condylar Hyperplasia.

    Xiao, Junhong / Wu, Zhongxing / Ye, Wengwanyue

    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons

    2021  Volume 80, Issue 2, Page(s) 285.e1–285.e9

    Abstract: Purpose: To evaluate the accuracy of single-photon emission computed tomography (SPECT) in diagnosing unilateral condylar hyperplasia (UCH) and to describe the condylar growth of patients with UCH.: Materials and methods: Using a retrospective study ... ...

    Abstract Purpose: To evaluate the accuracy of single-photon emission computed tomography (SPECT) in diagnosing unilateral condylar hyperplasia (UCH) and to describe the condylar growth of patients with UCH.
    Materials and methods: Using a retrospective study design, patients with UCH who had undergone SPECT and cone-beam computed tomography (CBCT) examinations at the same time were included in the study. We used 3D medical models based on CBCT data as the gold standard. The SPECT results were compared with the model data, and the sensitivity and specificity were calculated. To further describe the condylar growth activity, statistical analysis was performed, and the P value was set at 0.05.
    Results: The sample was composed of 75 patients. The sensitivity of SPECT was 55.3%, the specificity was 48.6%, and the area under the receiver operating characteristic curve was 0.53. There was no significant difference in sex between patients with and without active growth.
    Conclusion: The sensitivity and specificity of SPECT are poor, and SPECT alone is not suitable for evaluating the active stage of condylar growth. 3D medical modeling has good prospects for application in the diagnosis of condylar hyperplasia.
    MeSH term(s) Humans ; Hyperplasia/diagnostic imaging ; Mandibular Condyle/diagnostic imaging ; Mandibular Condyle/pathology ; Retrospective Studies ; Sensitivity and Specificity ; Tomography, Emission-Computed, Single-Photon
    Language English
    Publishing date 2021-09-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392404-x
    ISSN 1531-5053 ; 0278-2391
    ISSN (online) 1531-5053
    ISSN 0278-2391
    DOI 10.1016/j.joms.2021.09.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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