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Article ; Online: Azadirachtin Inhibits Nuclear Receptor

Fan, Shu-Ting / Wu, Mian-Zhi / Liu, Chang / Li, Hua-Hong / Huang, Shang-Huan / Zheng, Zi-Jing / Ye, Xi-Yu / Tan, Jin-Fang / Zhu, Guan-Heng

Journal of agricultural and food chemistry

2023  Volume 71, Issue 42, Page(s) 15497–15505

Abstract: Azadirachtin has been used to control agricultural pests for a long time; however, the molecular mechanism of azadirachtin on lepidopterans is still not clear. In this study, the fourth instar larvae of fall armyworm were fed with azadirachtin, and then ... ...

Abstract Azadirachtin has been used to control agricultural pests for a long time; however, the molecular mechanism of azadirachtin on lepidopterans is still not clear. In this study, the fourth instar larvae of fall armyworm were fed with azadirachtin, and then the ecdysis was blocked in the fourth instar larval stage (L4). The prothoracic glands (PGs) of the treated larvae were dissected for RNA sequencing to determine the effect of azadirachtin on ecdysis inhibition. Interestingly, one of the PG-enriched genes, the nuclear hormone receptor 3 (
MeSH term(s) Animals ; Molting/genetics ; Larva/metabolism ; Spodoptera/genetics ; Receptors, Cytoplasmic and Nuclear/genetics ; Receptors, Cytoplasmic and Nuclear/metabolism
Chemical Substances azadirachtin (O4U1SAF85H) ; Receptors, Cytoplasmic and Nuclear
Language English
Publishing date 2023-10-16
Publishing country United States
Document type Journal Article
ZDB-ID 241619-0
ISSN 1520-5118 ; 0021-8561
ISSN (online) 1520-5118
ISSN 0021-8561
DOI 10.1021/acs.jafc.3c05508
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