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  1. Article: Challenges During the Coronavirus Disease 2019 Pandemic: Diabetes Control and Psychosocial Issues in Children with Type 1 Diabetes Mellitus and Their Mothers.

    Canoruç Emet, Dicle / Yeşil, Ayşe Mete / Çelik, Berna / Şencan, Buse / Ünsal, Yağmur / Gönç, Nazlı / Özön, Alev / Özmert, Elif Nursel / Alikaşifoğlu, Ayfer

    Turkish archives of pediatrics

    2023  Volume 58, Issue 4, Page(s) 418–424

    Abstract: Objective: Governments have enforced restrictions to prevent the spread of coronavirus dis- ease 2019, which has affected lifestyle and psychosocial well-being. The aim of this study is to examine the psychosocial dimensions of children with type 1 ... ...

    Abstract Objective: Governments have enforced restrictions to prevent the spread of coronavirus dis- ease 2019, which has affected lifestyle and psychosocial well-being. The aim of this study is to examine the psychosocial dimensions of children with type 1 diabetes mellitus and lifestyle changes in the face of the pandemic.
    Materials and methods: Sixty school-aged children with type 1 diabetes mellitus were included to evaluate socioeconomic status, lifestyle changes, and psychological state after a 3-month school closure, using a questionnaire as well as scales in children and mothers [Depression-Anx iety-Stress Scale (short-form), Revised Child Anxiety-Depression Scale (parent-version), The Perceived Stress Scale in Children] via a Google® Form. The effect of pre-pandemic glycemic control on lifestyle and factors affecting HbA1c change were also investigated.
    Results: The percentage of mothers having scale scores above the cutoff in terms of stress, anxiety, and depression were 18.3%, 23.3%, and 33.3%, respectively. Mother's and children's anxiety, depression, and stress scores were positively correlated. Employed mothers had higher depression scores. Paternal unemployment increased the anxiety of the mothers. Seventy-eight percent (n = 46) of the mothers thought that diabetes in their children increased the risk of coro- navirus disease 2019 infection, and children of these mothers had higher depression, anxiety, and stress scores(P = .01, P < .01, P < .01). The majority of participants were adversely affected by coronavirus disease 2019 in terms of daily routines and dietary compliance. Patients with poor-controlled type 1 diabetes mellitus deteriorated more in terms of diet compliance (P = .01).
    Conclusion: Coronavirus disease 2019 affects the psychosocial dimensions in the family of chil- dren with type 1 diabetes mellitus. The psychosocial impact is reflected within the family and may affect diabetic control. Thus, it should be handled within the context of family. The provi- sion of proper information and guidance to parents may be crucial to alleviate the psychosocial burden on the family during the pandemic.
    Language English
    Publishing date 2023-06-24
    Publishing country Turkey
    Document type Journal Article
    ISSN 2757-6256
    ISSN 2757-6256
    DOI 10.5152/TurkArchPediatr.2023.23030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: DOCK8 deficiency with hypereosinophilia and the syndrome of inappropriate antidiuretic hormone secretion during herpes infection.

    Yeşil, Ayşe Mete / Kayaoğlu, Başak / Gül, Ersin / Gönç, Nazlı / Özön, Alev / Tezcan, İlhan / Gürsel, Mayda / Çağdaş, Deniz

    The Turkish journal of pediatrics

    2023  Volume 65, Issue 3, Page(s) 536–541

    Abstract: Background: Hyperimmunoglobulin E syndrome (HIES) due to dedicator of cytokinesis8 (DOCK8) deficiency may present in infancy and childhood with different clinical features involving recurrent infections, allergic dysregulation, and autoimmunity.: Case! ...

    Abstract Background: Hyperimmunoglobulin E syndrome (HIES) due to dedicator of cytokinesis8 (DOCK8) deficiency may present in infancy and childhood with different clinical features involving recurrent infections, allergic dysregulation, and autoimmunity.
    Case: In this report, we describe a patient who first presented with severe hypereosinophilia and went on to develop the syndrome of inappropriate antidiuretic hormone secretion (SIADH) in the context of a severe herpes infection. Investigation revealed the presence of underlying DOCK8 deficiency presenting with atypical clinical features.
    Conclusions: Distinct inflammatory features associated with infections may be seen in the course of primary immunodeficiency diseases, and early functional and molecular genetic tests will aid the proper management.
    MeSH term(s) Child ; Humans ; Eosinophilia ; Guanine Nucleotide Exchange Factors/genetics ; Hypersensitivity/complications ; Inappropriate ADH Syndrome/diagnosis ; Inappropriate ADH Syndrome/genetics ; Inappropriate ADH Syndrome/complications ; Job Syndrome/complications ; Job Syndrome/diagnosis ; Job Syndrome/genetics ; Vasopressins ; Infant
    Chemical Substances DOCK8 protein, human ; Guanine Nucleotide Exchange Factors ; Vasopressins (11000-17-2)
    Language English
    Publishing date 2023-06-15
    Publishing country Turkey
    Document type Case Reports ; Research Support, Non-U.S. Gov't
    ZDB-ID 123487-0
    ISSN 2791-6421 ; 0041-4301
    ISSN (online) 2791-6421
    ISSN 0041-4301
    DOI 10.24953/turkjped.2020.1934
    Database MEDical Literature Analysis and Retrieval System OnLINE

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