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  1. Article ; Online: Good quality white-light transurethral resection of bladder tumours (GQ-WLTURBT) with experienced surgeons performing complete resections and obtaining detrusor muscle reduces early recurrence in new non-muscle-invasive bladder cancer: validation across time and place and recommendation for benchmarking.

    Yeo, Lehana / Jain, Sunjay

    BJU international

    2012  Volume 109, Issue 8, Page(s) E27; author reply E27–8

    MeSH term(s) Clinical Competence ; Cystectomy ; Cystoscopy ; Female ; Humans ; Male ; Neoplasm Recurrence, Local/pathology ; Urinary Bladder Neoplasms/surgery
    Language English
    Publishing date 2012-04
    Publishing country England
    Document type Comment ; Letter
    ZDB-ID 1462191-5
    ISSN 1464-410X ; 1464-4096 ; 1358-8672
    ISSN (online) 1464-410X
    ISSN 1464-4096 ; 1358-8672
    DOI 10.1111/j.1464-410X.2012.11011_3.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The accuracy of magnetic resonance imaging (MRI) in predicting the invasion of the tunica albuginea and the urethra during the primary staging of penile cancer.

    Hanchanale, Vishwanath / Yeo, Lehana / Subedi, Nawraj / Smith, Jonathan / Wah, Tze / Harnden, Patricia / Bhattarai, Selina / Chilka, Sameer / Eardley, Ian

    BJU international

    2016  Volume 117, Issue 3, Page(s) 439–443

    Abstract: Objectives: To assess the accuracy of magnetic resonance imaging (MRI) in predicting invasion of the tunica albuginea (TA) and the urethra during the primary staging of penile cancer.: Patients and methods: In all, 104 consecutive patients with ... ...

    Abstract Objectives: To assess the accuracy of magnetic resonance imaging (MRI) in predicting invasion of the tunica albuginea (TA) and the urethra during the primary staging of penile cancer.
    Patients and methods: In all, 104 consecutive patients with clinical T1-T3 penile cancer had a penile MRI as a part of local staging protocol. An artificial erection was induced before MRI by injecting alprostadil (prostaglandin E1 ). Four men with poor quality MRI images were excluded from the study. The preoperative MRI was compared with final histology to assess its accuracy in predicting the invasion of the TA and urethra.
    Results: Data of 100 patients who underwent penile MRI before definitive surgery for invasive penile carcinoma were available for analysis. The mean age was 65 years and number of patients with pathological stage T1, T2 and T3 was 32, 52, and 16, respectively. The sensitivity and specificity of MRI in predicting the invasion of TA and urethra was 82.1% and 73.6%, and 62.5% and 82.1%, respectively. There were no MRI-related complications.
    Conclusions: This study shows that penile MRI is an accurate method for assessing TA invasion but is less sensitive in assessing urethral invasion. These results support the use of MRI in the local staging of penile cancer.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Humans ; Magnetic Resonance Imaging/standards ; Male ; Middle Aged ; Neoplasm Invasiveness/pathology ; Neoplasm Staging ; Penile Neoplasms/pathology ; Sensitivity and Specificity ; Urethral Neoplasms/pathology
    Language English
    Publishing date 2016-03
    Publishing country England
    Document type Comparative Study ; Evaluation Studies ; Journal Article
    ZDB-ID 1462191-5
    ISSN 1464-410X ; 1464-4096 ; 1358-8672
    ISSN (online) 1464-410X
    ISSN 1464-4096 ; 1358-8672
    DOI 10.1111/bju.13041
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  3. Article ; Online: Urinary tract dysfunction in Parkinson's disease: a review.

    Yeo, Lehana / Singh, Rajindra / Gundeti, Mohan / Barua, Jayanta M / Masood, Junaid

    International urology and nephrology

    2011  Volume 44, Issue 2, Page(s) 415–424

    Abstract: Introduction: Parkinson's disease is an extrapyramidal neurological disorder. Although motor symptoms are a predominant feature of the condition, non-motor symptoms have also been recognized. Urinary symptoms are frequently present in patients affected ... ...

    Abstract Introduction: Parkinson's disease is an extrapyramidal neurological disorder. Although motor symptoms are a predominant feature of the condition, non-motor symptoms have also been recognized. Urinary symptoms are frequently present in patients affected with Parkinson's disease (PD). Symptoms such as urgency, frequency, nocturia and urge incontinence significantly impact the patient's quality of life. We discuss the urinary dysfunction seen in patients with Parkinson's disease and consider the pathophysiology, important differentials, the investigations and management options for such patients.
    Materials and methods: An extensive search was performed using the PubMed(®)/EMBASE(®) databases to identify the available literature on urinary disturbances and Parkinson's disease. Reference was also made to current national guidelines on Parkinson's disease.
    Results: Urinary disturbances are frequently observed in sufferers of Parkinson's disease resulting in significant impact to the individual's quality of life. Studies report that storage symptoms are present in 57-83% of patients, whereas voiding symptoms are seen in 17-27% patients. Out of all the urinary symptoms, nocturia is the most common complaint in >60% patients with PD. Urgency occurs in 33-54% of patients, whilst frequency is experienced by 16-36% of patients. Detrusor overactivity (DO) is the commonest cystometric abnormality in patients with PD. The rate of neurogenic DO in patients with PD is 45-93%. The main differential to consider is Multiple System Atrophy (MSA) in which all patients are ultimately afflicted with urinary disturbance. It is well recognized that patients initially diagnosed with PD may in fact have MSA, and it is important to distinguish the two as their urological management is different. Patients presenting with refractory LUTS with concurrent PD should undergo full urodynamic investigation including cystometry, flowmetry and ultrasonography before treatment is initiated.
    Discussion: Referral to a urologist is advised in those with persistent or refractory urinary complaints. Urodynamic evaluation allows determination of the underlying bladder disorder; however, post-void residuals suffice in the uncomplicated patient. The pathophysiology of urinary dysfunction and current investigation and treatment modalities are discussed.
    MeSH term(s) Humans ; Parkinson Disease/complications ; Parkinson Disease/physiopathology ; Urination Disorders/etiology ; Urination Disorders/physiopathology ; Urodynamics
    Language English
    Publishing date 2011-05-07
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 204048-7
    ISSN 1573-2584 ; 0301-1623 ; 0042-1162
    ISSN (online) 1573-2584
    ISSN 0301-1623 ; 0042-1162
    DOI 10.1007/s11255-011-9969-y
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  4. Article ; Online: Should urologists in the UK undertake their own nephrostomies and renal access for endourological procedures: what does the future hold?

    Masood, Junaid / Yeo, Lehana / Zaman, Faruquz / El-Husseiny, Tamer / Moraitis, Konstantinos / Maan, Zafar / Buchholz, Noor

    BJU international

    2009  Volume 104, Issue 6, Page(s) 755–757

    MeSH term(s) Forecasting ; Humans ; Nephrostomy, Percutaneous/trends ; Physician's Role ; Professional Practice ; Radiography, Interventional/trends ; Radiology/trends ; United Kingdom ; Urology/education ; Urology/trends
    Language English
    Publishing date 2009-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 1462191-5
    ISSN 1464-410X ; 1464-4096 ; 1358-8672
    ISSN (online) 1464-410X
    ISSN 1464-4096 ; 1358-8672
    DOI 10.1111/j.1464-410X.2009.08711.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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