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  1. Article ; Online: Prevalence and associated factors of hyperuricemia among urban adults aged 35-79 years in southwestern China: a community-based cross-sectional study.

    Huang, Xiao-Bo / Zhang, Wen-Qiang / Tang, Wei-Wei / Liu, Ya / Ning, Yuan / Huang, Chuan / Liu, Jian-Xiong / Yi, Yan-Jing / Xu, Rong-Hua / Wang, Tzung-Dau

    Scientific reports

    2020  Volume 10, Issue 1, Page(s) 15683

    Abstract: Hyperuricemia is prevalent throughout the world. However, a well-designed large-scale epidemiological investigation of hyperuricemia in southwestern China is lacking. A regional representative sample of 10,141 participants were included using multistage, ...

    Abstract Hyperuricemia is prevalent throughout the world. However, a well-designed large-scale epidemiological investigation of hyperuricemia in southwestern China is lacking. A regional representative sample of 10,141 participants were included using multistage, stratified sampling in Chengdu and Chongqing from September 2013 to March 2014. Hyperuricemia was defined as the self-reported of the doctor's diagnosis of hyperuricemia, or serum uric acid > 420 μmol/L in men or serum uric acid > 360 μmol/L in women. The overall age- and sex-standardized prevalence of hyperuricemia among adults aged 35-79 years was 13.5%. Compared with women, the prevalence of hyperuricemia in men was higher (17.3% versus 10.0%). Hypertension, hyperlipidemia, overweight or obesity, central obesity were associated with an increased risk for hyperuricemia both in men and in women. Married men and women were not susceptible to hyperuricemia. Current cigarette smoking was an associated risk factor of hyperuricemia only in women. Hyperuricemia has become a major health problem among urban adults aged 35-79 years in southwestern China, and special attention should be paid to men. Comorbidities associated with hyperuricemia and causality worth further investigation.
    MeSH term(s) Adult ; Aged ; China/epidemiology ; Comorbidity ; Cross-Sectional Studies ; Female ; Humans ; Hyperuricemia/blood ; Hyperuricemia/epidemiology ; Male ; Middle Aged ; Prevalence ; Residence Characteristics/statistics & numerical data ; Risk Factors ; Urban Population/statistics & numerical data ; Uric Acid/blood
    Chemical Substances Uric Acid (268B43MJ25)
    Language English
    Publishing date 2020-09-24
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-020-72780-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Prevalence and Associated Factors of Diabetes Mellitus in a Very Elderly Chinese Population: A Cross-sectional Study.

    Liang, Bin / Tang, Wei Wei / Zhang, Wen Qiang / Huang, Chuan / Liu, Ya / Xu, Fan / Liu, Xin / Yuan, Ning / Liu, Jian Xiong / Yi, Yan Jing / Xu, Rong Hua / Hu, Dan / Huang, Xiao Bo / Cao, Xin

    Biomedical and environmental sciences : BES

    2020  Volume 33, Issue 5, Page(s) 315–322

    Abstract: Objectives: This paper aimed to investigate the prevalence of diabetes mellitus (DM) and explore the associated risk factors in a very elderly southwest Chinese population.: Methods: From September 2015 to June 2016, a cross-sectional survey was ... ...

    Abstract Objectives: This paper aimed to investigate the prevalence of diabetes mellitus (DM) and explore the associated risk factors in a very elderly southwest Chinese population.
    Methods: From September 2015 to June 2016, a cross-sectional survey was conducted to obtain a representative sample of 1,326 participants over 80 years old living in Chengdu. The presence of DM was based on fasting plasma glucose (FPG) and 2-h plasma glucose (2-hPG) levels during an oral glucose tolerance test (OGTT). A logistic regression model was used to calculate the odds ratios (
    Results: The participants' mean age was 83.5 ± 3.1 years. The overall prevalence of DM was 27.4%. The prevalence was higher in males (30.2%) than females (24.7%) (
    Conclusions: The prevalence of DM and newly diagnosed DM in a very elderly southwest Chinese population was high. OGTT screening should be performed regularly in people aged ≥ 80 years to ensure timely diagnosis of DM.
    MeSH term(s) Aged, 80 and over ; China/epidemiology ; Cross-Sectional Studies ; Diabetes Mellitus/epidemiology ; Female ; Humans ; Male ; Prevalence ; Risk Factors
    Language English
    Publishing date 2020-06-17
    Publishing country China
    Document type Journal Article
    ZDB-ID 645083-0
    ISSN 2214-0190 ; 0895-3988
    ISSN (online) 2214-0190
    ISSN 0895-3988
    DOI 10.3967/bes2020.043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Prevalence, awareness, treatment, and control of hypertension in southwestern China.

    Huang, Xiao-Bo / Zhang, Yang / Wang, Tzung-Dau / Liu, Jian-Xiong / Yi, Yan-Jing / Liu, Ya / Xu, Rong-Hua / Hu, Yong-Mei / Chen, Mao

    Scientific reports

    2019  Volume 9, Issue 1, Page(s) 19098

    Abstract: This study investigated the prevalence, awareness, treatment, and control of hypertension and associated factors among urban adults in southwestern China. The study was conducted from 2013-2014 and used a multistage cluster sampling method to select a ... ...

    Abstract This study investigated the prevalence, awareness, treatment, and control of hypertension and associated factors among urban adults in southwestern China. The study was conducted from 2013-2014 and used a multistage cluster sampling method to select a representative sample of 11,517 people in southwestern China, aged 35-79 years. Hypertension was defined as either systolic blood pressure of 140 mmHg or greater, diastolic blood pressure of 90 mm Hg or greater, or self-reported current treatment for hypertension with antihypertensive medications. In the study population, hypertension prevalence was found to be 38.4%, with rates of 40.0% and 37.5% for men and women, respectively (p = 0.03). Hypertension prevalence increased with age in both men and women (trend p both <0.01). Among hypertensive patients, 47.9% were aware of their hypertension, 40.1% were undergoing antihypertensive treatment, and 10.3% achieved BP control. A multiple-factor analysis revealed that age, male gender, low educational achievement, family history of hypertension, overweight or obesity, abdominal obesity, and hypertriglyceridemia were positively related to hypertension, while physical exercise was negatively related to hypertension. The prevalence of hypertension among urban adults aged 35 to 79 years in southwestern China was high, while levels of awareness, treatment, and control of hypertension were low. Multifaceted interventional measures are needed to solve the unmet needs.
    MeSH term(s) Adult ; Aged ; Antihypertensive Agents/pharmacology ; Attitude to Health ; Blood Pressure ; China/epidemiology ; Cities ; Cluster Analysis ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Hypertension/epidemiology ; Hypertension/therapy ; Male ; Middle Aged ; Multivariate Analysis ; Obesity/complications ; Overweight/drug therapy ; Prevalence ; Risk Factors ; Sex Factors ; Urban Population
    Chemical Substances Antihypertensive Agents
    Language English
    Publishing date 2019-12-13
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-019-55438-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: High prevalence of obesity-related hypertension among adults aged 40 to 79 years in Southwest China.

    Zhang, Yang / Hou, Li-Sha / Tang, Wei-Wei / Xu, Fan / Xu, Rong-Hua / Liu, Xin / Liu, Ya / Liu, Jian-Xiong / Yi, Yan-Jing / Hu, Tai-Shang / Hu, Rong / Wang, Tzung-Dau / Huang, Xiao-Bo

    Scientific reports

    2019  Volume 9, Issue 1, Page(s) 15838

    Abstract: This study aimed to assess the prevalence and related factors of obesity-related hypertension among adults aged 40 to 79 years in Southwest China. From September 2013 to March 2014, a multi-stage, stratified sampling method was conducted on 10,589 people ...

    Abstract This study aimed to assess the prevalence and related factors of obesity-related hypertension among adults aged 40 to 79 years in Southwest China. From September 2013 to March 2014, a multi-stage, stratified sampling method was conducted on 10,589 people aged 40 to 79 years and living in Chengdu and Chongqing investigated by using a questionnaire and performing physical and biochemical measurements. The prevalence of obesity-related hypertension and hypertension overall (systolic ≥130 mmHg and/or diastolic ≥80 mmHg or treated hypertension) was 22.8% and 57.4%, respectively, among all participants. For obesity-related hypertension, the prevalence was higher in women than in men (24.7% versus 19.4%, p < 0.001). For people in the age ranges of 40-49, 50-59, 60-69, and ≥70, the prevalence of obesity-related hypertension were 11.8%, 22.6%, 30.7%, and 36.6%, respectively. Participants with obesity-related hypertension as opposed to those with non-obesity-related hypertension had a higher prevalence of hypertriglyceridemia, high low-density lipoprotein cholesterolemia, diabetes, and hyperuricemia (all p < 0.05). Multivariate logistic regression analysis showed that age, female gender, current smoking, hypertriglyceridemia, diabetes and family history of hypertension were all positively correlated with obesity-related hypertension, whereas higher education level and having spouse were negatively correlated with obesity-related hypertension. The prevalence of obesity-related hypertension was high among adults aged 40 to 79 years in Southwest China. Cardiometabolic abnormalities among participants with obesity-related hypertension were more serious and frequently present than in those with non-obesity-related hypertension. Aggressive and holistic strategies aiming at the prevention and treatment of obesity-related hypertension are needed.
    MeSH term(s) Adult ; Age Factors ; Aged ; China/epidemiology ; Female ; Humans ; Hypertension/epidemiology ; Hypertension/physiopathology ; Male ; Middle Aged ; Obesity/epidemiology ; Obesity/physiopathology ; Prevalence ; Sex Factors
    Language English
    Publishing date 2019-11-01
    Publishing country England
    Document type Clinical Trial ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-019-52132-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Prevalence and risk factors associated with hypertension in the Chinese Qiang population.

    Huang, Xiao-Bo / Chen, Fei / Dai, Wen / Song, Lei / Tu, Jiao / Xu, Jun-Bo / Liu, Jian-Xiong / Yi, Yan-Jing / Liu, Ya / Chen, Yong / Wang, Tzung-Dau / Zhao, Shui-Ping

    Clinical and experimental hypertension (New York, N.Y. : 1993)

    2017  Volume 40, Issue 5, Page(s) 427–433

    Abstract: Our aim is to investigate the prevalence and risk factors associated with hypertension among the Chinese Qiang population. From September 2012 to March 2013, a cross-sectional study was conducted in urban and rural communities of the Qiang population ... ...

    Abstract Our aim is to investigate the prevalence and risk factors associated with hypertension among the Chinese Qiang population. From September 2012 to March 2013, a cross-sectional study was conducted in urban and rural communities of the Qiang population using multistage cluster sampling. A total of 2676 people aged above 20 years were enrolled in the analysis. Standardized mercury sphygmomanometer was used to measure the blood pressure twice after a 10-minute seated rest, and the average blood pressure was obtained. The hypertension prevalence among the population aged above 20 years was 13.9%, and age-standardized prevalence was 12.3%. Male and female prevalence of hypertension, as well as the prevalence in urban and rural areas, all increased with age. There were no significant differences between males and females and between urban and rural residents. Among hypertensive patients, 44.2% were aware of their hypertension, 38.0% were undergoing antihypertensive treatment, but only 10.5% achieved blood pressure control. Multivariate logistic regression analysis showed that the risk factors of hypertension included age, low income, overweight and obesity, family history of hypertension. The prevalence of hypertension in Chinese Qiang adults is significantly lower than the national level. Awareness, treatment, and control rates of hypertension were low in the Qiang population. Thus, hypertension-related health knowledge should be more aggressively delivered to improve public awareness and the capacity of community health services should be strengthened.
    MeSH term(s) Adult ; Age Factors ; Aged ; Antihypertensive Agents/therapeutic use ; Asian Continental Ancestry Group/statistics & numerical data ; Blood Pressure ; China/epidemiology ; Cross-Sectional Studies ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Hypertension/drug therapy ; Hypertension/ethnology ; Hypertension/genetics ; Income ; Male ; Middle Aged ; Obesity/epidemiology ; Prevalence ; Risk Factors ; Rural Population/statistics & numerical data ; Urban Population/statistics & numerical data ; Young Adult
    Chemical Substances Antihypertensive Agents
    Language English
    Publishing date 2017-11-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 604757-9
    ISSN 1525-6006 ; 0730-0077
    ISSN (online) 1525-6006
    ISSN 0730-0077
    DOI 10.1080/10641963.2017.1392553
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Prevalence of diabetes and unrecognized diabetes in hypertensive patients aged 40 to 79 years in southwest China.

    Huang, Xiao-Bo / Tang, Wei-Wei / Liu, Ya / Hu, Rong / Ouyang, Ling-Yun / Liu, Jian-Xiong / Li, Xiu-Jun / Yi, Yan-Jing / Wang, Tzung-Dau / Zhao, Shui-Ping

    PloS one

    2017  Volume 12, Issue 2, Page(s) e0170250

    Abstract: This study aimed to assess the prevalence of diabetes and unrecognized diabetes in hypertensive patients aged 40 to 79 years in Southwest China. From September 2013 to March 2014, a cross-sectional survey was conducted in 4021 hypertensive patients aged ... ...

    Abstract This study aimed to assess the prevalence of diabetes and unrecognized diabetes in hypertensive patients aged 40 to 79 years in Southwest China. From September 2013 to March 2014, a cross-sectional survey was conducted in 4021 hypertensive patients aged 40 to 79 years living in Chengdu and Chongqing, China. Fasting plasma glucose (FPG) and 2h plasma glucose (2-hPG) in an oral glucose-tolerance test (OGTT) were used for assessments. Whether the patients previously had diabetes (DM) was determined by their own reports. The survey was carried out by the same questionnaire for all respondents. DM prevalence was 32.0% in hypertensive patients aged 40 to 79 years in Southwest China, with the rates of 29.6% and 33.5% in men and women, respectively (P<0.001). DM prevalence increased with age age and body-mass index. DM prevalence rates were 16.9%, 24.7%, 38.2% and 41.9% in hypertensive patients aged 40-49, 50-59, 60-69 and over 70, respectively. DM prevalence were 30.6%, 27.9%, 37.1%, and 37.4%, for BMI<18.5, 18.5-24.9, 25.0-29.9, and ≥30, respectively. Prevalence of unrecognized DM were 20.8% in hypertensive patients aged 40 to 79 years in Southwest China. Using only fasting blood glucose testing without OGTT would have resulted in 65.0% of missed DM diagnosis in these newly diagnosed patients. The prevalence of DM and unrecognized DM were high in hypertensive patients aged 40 to 79 years in Southwest China.These findings indicate that hypertensive patients aged 40 to 79 years should regularly submit to community-based OGTT screening for timely DM diagnosis.
    MeSH term(s) Adult ; Aged ; Asian People ; Blood Glucose/analysis ; Blood Pressure ; Body Mass Index ; China/epidemiology ; Comorbidity ; Cross-Sectional Studies ; Diabetes Mellitus/blood ; Diabetes Mellitus/epidemiology ; Diabetes Mellitus/ethnology ; Fasting/blood ; Female ; Glucose Tolerance Test ; Humans ; Hypertension/blood ; Hypertension/epidemiology ; Hypertension/ethnology ; Lipids/blood ; Logistic Models ; Male ; Middle Aged ; Prevalence ; Surveys and Questionnaires
    Chemical Substances Blood Glucose ; Lipids
    Language English
    Publishing date 2017-02-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0170250
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: [An epidemiological study of abnormal glucose metabolism and its risk factors among middle and aged population with hypertension in Chengdu area].

    Yi, Yan-jing / Ran, Xun / Huang, Xiao-bo / Liu, Ya / Zhang, Ting-jie / Ouyang, Ling-yun / Zeng, Wei / Xu, Jun-bo / Yang, Lei / Liu, Yan / Li, Xiu-jun / Zhao, Si-qin

    Zhonghua nei ke za zhi

    2010  Volume 49, Issue 4, Page(s) 301–304

    Abstract: Objective: To explore the epidemiological status of abnormal glucose metabolism and its influential factors among middle and aged population with hypertension in Chengdu area.: Methods: In 2008, after adopting the methods of stratified cluster ... ...

    Abstract Objective: To explore the epidemiological status of abnormal glucose metabolism and its influential factors among middle and aged population with hypertension in Chengdu area.
    Methods: In 2008, after adopting the methods of stratified cluster sampling, the authors investigated 4685 subjects of the middle and aged population between the age of 40 - 79 in Chengdu urban and rural area by checking blood pressure and oral glucose tolerance test (OGTT). Patients with previously known diabetes mellitus (DM) were only asked to perform fasting glucose and to carry out a questionnaire. Comparison of the prevalence rates of abnormal glucose metabolism in hypertensive and non-hypertensive subjects was carried out. The prevalence rates of isolated impaired glucose tolerance (I-IGT) and isolated postprandial hyperglycemia (IPH) among middle and aged subjects with hypertension were acquired and the influential factors of abnormal glucose metabolism among middle and aged subjects with hypertension were analyzed.
    Results: The prevalence rate of abnormal glucose metabolism in the hypertensive subjects was obviously higher than that in the non-hypertensive subjects; without using OGTT, 72.9% of the pre-diabetic and 54.4% of the new diagnosed DM patients would remain undiagnosed if fasting plasma glucose detection was used alone. Age, diabetic history of first degree relatives, overweight or obesity were the risk factors for the development of abnormal glucose metabolism among middle and aged male subjects with hypertension in Chengdu area. Exercise training and high education level were the protective factors. Age, diabetic history of first degree relatives, abdominal obesity and hypertriglyceridemia were the risk factors for the development of abnormal glucose metabolism among middle and aged female subjects with hypertension in Chengdu area.
    Conclusions: More than 50% of middle and aged subjects with hypertension in Chengdu area has accompanying abnormal glucose metabolism. OGTT easily discloses the abnormal status and should be a routine procedure in the diagnosis of pre-diabetes or DM in such population. Appropriate exercise, learning diabetes-related knowledge to take reasonable lifestyle, and intervention of metabolic factors such as overweight or obesity are advised. Abdominal obesity and hypertriglyceridemia play important roles in leading to abnormal glucose metabolism among middle and aged population with hypertension.
    MeSH term(s) Adult ; Aged ; Blood Glucose/metabolism ; China/epidemiology ; Female ; Glucose Intolerance ; Glucose Metabolism Disorders/epidemiology ; Glucose Metabolism Disorders/metabolism ; Humans ; Hypertension/epidemiology ; Hypertension/metabolism ; Male ; Middle Aged ; Prevalence ; Risk Factors
    Chemical Substances Blood Glucose
    Language Chinese
    Publishing date 2010-04
    Publishing country China
    Document type English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 754223-9
    ISSN 0578-1426
    ISSN 0578-1426
    Database MEDical Literature Analysis and Retrieval System OnLINE

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