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Article: Relationship between

Liu, Yi-Ying / Wan, Qin

2023 Volume 14, Issue 12, Page(s) 1803–1812

Abstract: Background: Diabetic kidney disease is one of the common complications of type 2 diabetes (T2D). There are no typical symptoms in the early stage, and the disease will progress to moderate and late stage when albuminuria reaches a high level. Treatment ... ...

Abstract	Background: Diabetic kidney disease is one of the common complications of type 2 diabetes (T2D). There are no typical symptoms in the early stage, and the disease will progress to moderate and late stage when albuminuria reaches a high level. Treatment is difficult and the prognosis is poor. At present, the pathogenesis of diabetic kidney disease is still unclear, and it is believed that it is associated with genetic and environmental factors. Aim: To explore the relationship between the glucokinase regulatory protein ( Methods: We selected 252 patients (126 males and 126 females) with T2D admitted to our hospital from January 2020 to October 2020, and 66 healthy people (44 females and 22 males). According to the urinary albumin/creatinine ratio, the subjects were divided into group I (control), group II (T2D with normoalbuminuria), group III (T2D with microalbuminuria), and group IV (T2D with macroalbuminuria). Additionly, the subjects were divided into group M (normal group) or group N (albuminuria group) according to whether they developed albuminuria. We detected the Results: Gene distribution and genotype distribution among groups I-IV accorded with the Hardy-Weinberg equilibrium. Genotype frequency was significantly different among the four groups ( Conclusion: CT + TT genotype is a risk factor for T2D with albuminuria. In the future, we can assess the risk of individuals carrying susceptible genes to delay the onset of T2D.
Language	English
Publishing date	2023-12-04
Publishing country	United States
Document type	Clinical Trial
ZDB-ID	2583471-X
ISSN	1948-9358
ISSN	1948-9358
DOI	10.4239/wjd.v14.i12.1803
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Smartphone addiction, gender and interpersonal attachment: A cross-sectional analytical survey in Taiwan.

Wu, Yi-Ying / Chou, Wen-Huei

Digital health

2023 Volume 9, Page(s) 20552076231177134

Abstract: Overview: Smartphone use has dramatically increased worldwide, contributing to a profound change in interpersonal interactions. They have become the primary medium of human interaction, and smartphone addiction, consequently, has become a modern-day ... ...

Abstract	Overview: Smartphone use has dramatically increased worldwide, contributing to a profound change in interpersonal interactions. They have become the primary medium of human interaction, and smartphone addiction, consequently, has become a modern-day reality. Recent research on smartphone addiction has provided diverse explanations regarding the correlation between gender and addiction. Therefore, this study aims to analyse the correlation and variance among smartphone addiction, gender and interpersonal attachment. Methods: The participants included Taiwanese citizens and the questionnaires were randomly distributed; 1190 valid questionnaires (534 males, 656 females) were collected. Descriptive statistics were computed to observe the average value and standard deviation between interpersonal attachment and gender. Next, Spearman's ρ was conducted to interpret the correlation among smartphone addiction, gender and interpersonal attachment. Finally, the participants were divided into three groups based on their pre-determined level of smartphone addiction: high, moderate and low addictions. The Analysis of variance (ANOVA) was performed based on interpersonal attachment as the independent variable to determine any statistically significant difference among the three levels. Results: There are four patterns of interpersonal attachment: secure, avoidant, dismissing and anxious attachments. The correlation analysis revealed a significant positive correlation between interpersonal attachment and smartphone addiction ( Conclusion: This study revealed that there was no correlation between gender and smartphone addiction, but rather, a positive correlation between smartphone addiction and interpersonal attachment. This positive correlation suggests both high and moderate addiction groups display insecurity in their interpersonal attachment. Therefore, to lower the prevalence of unhealthy smartphone addiction, maintaining healthy interpersonal relationships is suggested.
Language	English
Publishing date	2023-05-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	2819396-9
ISSN	2055-2076
ISSN	2055-2076
DOI	10.1177/20552076231177134
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Article ; Online: A Bibliometric Analysis to Identify Research Trends in Intervention Programs for Smartphone Addiction.

Wu, Yi-Ying / Chou, Wen-Huei

International journal of environmental research and public health

2023 Volume 20, Issue 5

Abstract: Smartphone addiction is a serious social problem that necessitates research. To identify trends in intervention programs for smartphone addiction, distribution of research topics, and inter-relationships in academic research. We analyzed 104 studies ... ...

Abstract	Smartphone addiction is a serious social problem that necessitates research. To identify trends in intervention programs for smartphone addiction, distribution of research topics, and inter-relationships in academic research. We analyzed 104 studies published between 30 June 2022, and 31 August 2022, on the Web of Science (WoS). We applied the bibliometric method and identified the relationship and development trends of academic research in the field using descriptive analysis, the Latent Dirichlet Allocation (LDA), co-citation analysis, bibliographic coupling, and co-occurrence. There were four findings: First, intervention programs are classified into 10 types: psychological, social support, lifestyle, technological, family, medical care, educational, exercise, mindfulness, and meditation. Second, the volume of research on intervention programs increased every year. Third, China and South Korea had the highest research involvement. Finally, academic studies were split into either the human behavior or social science categories. Most of them defined the symptoms in terms of individual behavior and social relations, implying that smartphone addiction is not yet recognized as a disorder. Smartphone addiction has not yet been internationally recognized as a disorder, despite its impact on human physiology, psychology, and social behavior. Most related studies have been conducted in Asia, specifically in China and South Korea; Spain has the most outside Asia. Additionally, most of the research subjects were students, probably because of the convenience of sampling. As smartphones gain popularity among older adults, future studies could focus on smartphone addiction among individuals of varied ages.
MeSH term(s)	Humans ; Aged ; Internet Addiction Disorder ; Behavior Therapy ; Social Behavior ; Exercise ; Smartphone ; Bibliometrics ; Behavior, Addictive
Language	English
Publishing date	2023-02-21
Publishing country	Switzerland
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2175195-X
ISSN	1660-4601 ; 1661-7827
ISSN (online)	1660-4601
ISSN	1661-7827
DOI	10.3390/ijerph20053840
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Article ; Online: Metadherin promotes stem cell phenotypes and correlated with immune infiltration in hepatocellular carcinoma.

Wang, Yi-Ying / Shen, Mei-Mei / Gao, Jian

World journal of gastroenterology

2024 Volume 30, Issue 8, Page(s) 901–918

Abstract: Background: Metadherin (: Aim: To explore the role of : Methods: MTDH: Results: HCC tissues expressed higher levels of : Conclusion: High levels of MTDH expression in patients with HCC are associated with poor prognosis, promoting tumor ... ...

Abstract	Background: Metadherin ( Aim: To explore the role of Methods: MTDH Results: HCC tissues expressed higher levels of Conclusion: High levels of MTDH expression in patients with HCC are associated with poor prognosis, promoting tumor stemness, immune infiltration, and HCC progression.
MeSH term(s)	Humans ; Carcinoma, Hepatocellular/pathology ; Liver Neoplasms/pathology ; CD8-Positive T-Lymphocytes ; Transcription Factors/genetics ; Stem Cells/pathology ; Phenotype ; Cell Line, Tumor ; Membrane Proteins/genetics ; RNA-Binding Proteins/genetics
Chemical Substances	Transcription Factors ; MTDH protein, human ; Membrane Proteins ; RNA-Binding Proteins
Language	English
Publishing date	2024-03-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	2185929-2
ISSN	2219-2840 ; 1007-9327
ISSN (online)	2219-2840
ISSN	1007-9327
DOI	10.3748/wjg.v30.i8.901
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Article ; Online: Predicting the cryotolerance of boar sperm through antioxidant stress.

Wang, Shih-Chung / Wu, Yi-Ying / Chen, Ming-Cheng

Reproduction in domestic animals = Zuchthygiene

2024 Volume 59, Issue 4, Page(s) e14554

Abstract: High sperm cryotolerance is crucial to the successful cryopreservation of boar sperm. Evaluating the cryotolerance of boar sperm by using a rapid and convenient technique can enhance the commercial viability of these sperm. This study investigated the ... ...

Abstract	High sperm cryotolerance is crucial to the successful cryopreservation of boar sperm. Evaluating the cryotolerance of boar sperm by using a rapid and convenient technique can enhance the commercial viability of these sperm. This study investigated the correlation between sperm parameters for three sample subsets-fresh sperm, sperm with H
MeSH term(s)	Swine ; Male ; Animals ; Antioxidants/pharmacology ; Semen ; Hydrogen Peroxide/pharmacology ; Semen Preservation/veterinary ; Semen Preservation/methods ; Spermatozoa ; Cryopreservation/veterinary ; Cryopreservation/methods ; Sperm Motility
Chemical Substances	Antioxidants ; Hydrogen Peroxide (BBX060AN9V)
Language	English
Publishing date	2024-04-03
Publishing country	Germany
Document type	Journal Article
ZDB-ID	1015187-4
ISSN	1439-0531 ; 0936-6768
ISSN (online)	1439-0531
ISSN	0936-6768
DOI	10.1111/rda.14554
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Article ; Online: A Bibliometric Analysis to Identify Research Trends in Intervention Programs for Smartphone Addiction

Yi-Ying Wu / Wen-Huei Chou

International Journal of Environmental Research and Public Health, Vol 20, Iss 3840, p

2023 Volume 3840

Abstract	Smartphone addiction is a serious social problem that necessitates research. To identify trends in intervention programs for smartphone addiction, distribution of research topics, and inter-relationships in academic research. We analyzed 104 studies published between 30 June 2022, and 31 August 2022, on the Web of Science (WoS). We applied the bibliometric method and identified the relationship and development trends of academic research in the field using descriptive analysis, the Latent Dirichlet Allocation (LDA), co-citation analysis, bibliographic coupling, and co-occurrence. There were four findings: First, intervention programs are classified into 10 types: psychological, social support, lifestyle, technological, family, medical care, educational, exercise, mindfulness, and meditation. Second, the volume of research on intervention programs increased every year. Third, China and South Korea had the highest research involvement. Finally, academic studies were split into either the human behavior or social science categories. Most of them defined the symptoms in terms of individual behavior and social relations, implying that smartphone addiction is not yet recognized as a disorder. Smartphone addiction has not yet been internationally recognized as a disorder, despite its impact on human physiology, psychology, and social behavior. Most related studies have been conducted in Asia, specifically in China and South Korea; Spain has the most outside Asia. Additionally, most of the research subjects were students, probably because of the convenience of sampling. As smartphones gain popularity among older adults, future studies could focus on smartphone addiction among individuals of varied ages.
Keywords	smartphone addiction ; research trend ; intervention program ; bibliometric analysis ; LDA ; Medicine ; R
Subject code	001
Language	English
Publishing date	2023-02-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: The heterogeneity of the COVID-19 pandemic and national responses

Yi-Ying Chen / Yibeltal Assefa

BMC Public Health, Vol 21, Iss 1, Pp 1-

an explanatory mixed-methods study

2021 Volume 15

Abstract: Abstract Background The coronavirus disease of 2019 (COVID-19) has quickly spread to all corners of the world since its emergence in Wuhan, China in December of 2019. The disease burden has been heterogeneous across regions of the world, with Americas ... ...

Abstract	Abstract Background The coronavirus disease of 2019 (COVID-19) has quickly spread to all corners of the world since its emergence in Wuhan, China in December of 2019. The disease burden has been heterogeneous across regions of the world, with Americas leading in cumulative cases and deaths, followed by Europe, Southeast Asia, Eastern Mediterranean, Africa and Western Pacific. Initial responses to COVID-19 also varied between governments, ranging from proactive containment to delayed intervention. Understanding these variabilities allow high burden countries to learn from low burden countries on ways to create more sustainable response plans in the future. Methods This study used a mixed-methods approach to perform cross-country comparisons of pandemic responses in the United States (US), Brazil, Germany, Australia, South Korea, Thailand, New Zealand, Italy and China. These countries were selected based on their income level, relative COVID-19 burden and geographic location. To rationalize the epidemiological variability, a list of 14 indicators was established to assess the countries’ preparedness, actual response, and socioeconomic and demographic profile in the context of COVID-19. Results As of 1 April 2021, the US had the highest cases per million out of the nine countries, followed by Brazil, Italy, Germany, South Korea, Australia, New Zealand, Thailand and China. Meanwhile, Italy ranked first out of the nine countries’ total deaths per million, followed by the US, Brazil, Germany, Australia, South Korea, New Zealand, China and Thailand. The epidemiological differences between these countries could be explained by nine indicators, and they were 1) leadership, governance and coordination of response, 2) communication, 3) community engagement, 4) multisectoral actions, 5) public health capacity, 6) universal health coverage, 7) medical services and hospital capacity, 8) demography and 9) burden of non-communicable diseases. Conclusion The COVID-19 pandemic manifests varied outcomes due to differences in ...
Keywords	COVID-19 pandemic response ; Australia ; Brazil ; China ; Germany ; Italy ; Public aspects of medicine ; RA1-1270
Subject code	950
Language	English
Publishing date	2021-05-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Correlation of serum uromodulin levels with renal fibrosis and renal function progression in patients with CKD.

Jie, Chen / Yi-Ying, Ying / Miao, Chen

Pakistan journal of pharmaceutical sciences

2021 Volume 34, Issue 6(Special), Page(s) 2417–2422

Abstract: To explore the relationship of serum uromodulin levels with renal function progression and renal fibrosis in chronic kidney disease (CKD) patients. Totally 168 CKD patients treated in Department of Nephrology of the present hospital between June 2017 and ...

Abstract	To explore the relationship of serum uromodulin levels with renal function progression and renal fibrosis in chronic kidney disease (CKD) patients. Totally 168 CKD patients treated in Department of Nephrology of the present hospital between June 2017 and June 2019 were recruited. These patients were allocated to the deterioration and control groups according to the estimated glomerular filtration rate (eGFR). Multi-factor Logistic regression analysis was utilized for the correlation factors influencing renal function progression and the correlation between serum uromodulin and renal fibrosis was also compared. Number of patients receiving ARB or ACEI drugs intervention was lower in the deterioration group than that in the control group (P<0.05). 24-hour urine protein quantification and HA were higher, while eGFR and uromodulin were lower in the deterioration group compared with the control group (both P<0.05). eGFR (OR=0.373) and uromodulin (OR=0.717) were the protective factors for renal function progression. The risk of renal fibrosis was higher in the deterioration group compared with the control group (P<0.05). Uromodulin was significantly higher in the fibrosis group compared with the normal group (P<0.05). Serum uromodulin is an independent risk factor for renal function progression, and is remarkably correlated with renal fibrosis, which deserves clinical promotion.
MeSH term(s)	Adult ; Aged ; Biomarkers/blood ; Case-Control Studies ; Disease Progression ; Female ; Fibrosis ; Glomerular Filtration Rate ; Humans ; Kidney/metabolism ; Kidney/pathology ; Kidney/physiopathology ; Male ; Middle Aged ; Predictive Value of Tests ; Renal Insufficiency, Chronic/blood ; Renal Insufficiency, Chronic/diagnosis ; Renal Insufficiency, Chronic/physiopathology ; Risk Assessment ; Risk Factors ; Uromodulin/blood
Chemical Substances	Biomarkers ; UMOD protein, human ; Uromodulin
Language	English
Publishing date	2021-11-17
Publishing country	Pakistan
Document type	Journal Article
ZDB-ID	885131-1
ISSN	1011-601X
ISSN	1011-601X
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Book ; Online: Tropical cyclones facilitate recovery of forest leaf area from dry spells in East Asia

Chen, Yi-Ying / Luyssaert, Sebastiaan

eISSN: 1726-4189

2023

Abstract: Forests disturbance by tropical cyclones is mostly documented by field studies of exceptionally strong cyclones and satellite-based approaches attributing decreases in leaf area. By starting their analysis from the observed damage, these studies are ... ...

Abstract	Forests disturbance by tropical cyclones is mostly documented by field studies of exceptionally strong cyclones and satellite-based approaches attributing decreases in leaf area. By starting their analysis from the observed damage, these studies are biased and may, therefore, limit our understanding of the impact of cyclones in general. This study overcomes such biases by jointly analyzing the cyclone tracks, climate reanalysis, and changes in satellite-based leaf area following the passage of 140 ± 41 cyclones. Sixty days following their passage, 18 ± 8 % of the cyclones resulted in a decrease and 48 ± 18 % showed no change in leaf area compared to nearby forest outside the storm track. For a surprising 34 ± 7 % of the cyclones, an increase in leaf area was observed. Cyclones resulting in higher leaf area in their affected compared to their reference area coincided with an atmospheric pressure dipole steering the cyclone towards a region experiencing a dry spell caused by the same dipole. When the dipole was present, the destructive power of cyclones was offset by their abundant precipitation enabling forest canopies in the affected area to recover faster from the dry spell than canopies in the reference area. This study documents previously undocumented widespread antagonist interactions on forest leaf area between tropical cyclones and droughts.
Subject code	910
Language	English
Publishing date	2023-01-20
Publishing country	de
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Monitoring changes in the genetic structure of Brown Tsaiya duck selected for feeding efficiency by microsatellite markers

Yi-Ying Chang / Hsiu-Chou Liu / Chih-Feng Chen

Animal Bioscience, Vol 36, Iss 3, Pp 417-

2023 Volume 428

Abstract: Objective Few studies have genetically monitored chickens over time, and no research has been conducted on ducks. To ensure the sustainable management of key duck breeds, we used microsatellite markers to monitor Brown Tsaiya ducks over time genetically. ...

Abstract	Objective Few studies have genetically monitored chickens over time, and no research has been conducted on ducks. To ensure the sustainable management of key duck breeds, we used microsatellite markers to monitor Brown Tsaiya ducks over time genetically. Methods The second, fourth, sixth to eighth generations of the Brown Tsaiya duck selected for feeding efficiency and control lines were included in this study to investigate the genetic variations, effective population size, population structure and the differentiation between populations over time with 11 microsatellite markers derived from Brown Tsaiya duck. Results The results showed there were a slight decrease in the genetic variations and an increase in within-population inbreeding coefficient (FIS) in both lines, but no consistent increase in FIS was observed in each line. The effective population size in the second and eighth generations was 27.2 for the selected line and 23.9 for the control line. The change in allele richness showed a downward trend over time, and the selected line was slightly lower than the control line in each generation. The number of private alleles (Np) in the selected line were higher than in the control line. Moderate differentiation was observed between the second and eighth generations in the selected line (FST = 0.0510) and the control line (FST = 0.0606). Overall, differentiation tended to increase with each generation, but genetic variation and structure did not change considerably after six generations in the two lines. Conclusion This study provides a reference for poultry conservation and helps to implement cross-generation genetic monitoring and breeding plans in other duck breeds or lines to promote sustainable management.
Keywords	duck ; genetic monitoring ; microsatellite marker ; Zoology ; QL1-991
Subject code	630
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	Asian-Australasian Association of Animal Production Societies
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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