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  1. Article ; Online: Cost and health impact analysis of herpes zoster vaccination in Norway.

    Flem, Elmira / Graham, Jonathan / Yi, Zinan / Wisløff, Torbjørn / Johnson, Kelly D

    Expert review of pharmacoeconomics & outcomes research

    2021  Volume 22, Issue 2, Page(s) 315–326

    Abstract: Background: A decision analytic model was developed to estimate the cost-effectiveness of a national vaccination program against herpes zoster in Norway.: Methods: The model analyzed six vaccination scenarios that included the live-attenuated zoster ... ...

    Abstract Background: A decision analytic model was developed to estimate the cost-effectiveness of a national vaccination program against herpes zoster in Norway.
    Methods: The model analyzed six vaccination scenarios that included the live-attenuated zoster vaccine under different target ages of vaccination (60, 65, and 70 years) compared with no vaccination. A catch-up program implemented in the first year of the vaccination was included in three of the scenarios. The model followed the population of Norway over a 40-year time horizon to estimate costs and outcomes associated with vaccination. Immunization costs, costs related to herpes zoster (both healthcare sector and non-healthcasre sector), the quality of life gains due to avoided cases of herpes zoster, and quality-of-life losses due to vaccine-related adverse events were estimated.
    Results and conclusions: A national vaccination program would result in reduction of the number of herpes zoster cases and decreased burden of illness. Vaccinating adults at 65 years of age with catch-up up to 70 years in the first year of the program was the most cost-effective strategy with the incremental cost per quality-adjusted life-year gained at NOK (Norwegian Krone) 245,459 from the societal perspective and NOK 248,637 from the health care system perspective.
    MeSH term(s) Cost-Benefit Analysis ; Herpes Zoster/epidemiology ; Herpes Zoster/prevention & control ; Herpes Zoster Vaccine ; Humans ; Quality of Life ; Quality-Adjusted Life Years ; Vaccination
    Chemical Substances Herpes Zoster Vaccine
    Language English
    Publishing date 2021-09-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 2208481-2
    ISSN 1744-8379 ; 1473-7167
    ISSN (online) 1744-8379
    ISSN 1473-7167
    DOI 10.1080/14737167.2021.1973893
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Changes in cigarette smoking initiation, cessation, and relapse among U.S. adults: a comparison of two longitudinal samples.

    Yi, Zinan / Mayorga, Maria E / Hassmiller Lich, Kristen / Pearson, Jennifer L

    Tobacco induced diseases

    2017  Volume 15, Page(s) 17

    Abstract: Background: The tobacco epidemic in the U.S. has matured in the past decade. However, due to rapidly changing social policy and commercial environments, tailored prevention and interventions are needed to support further reduction in smoking.: Methods! ...

    Abstract Background: The tobacco epidemic in the U.S. has matured in the past decade. However, due to rapidly changing social policy and commercial environments, tailored prevention and interventions are needed to support further reduction in smoking.
    Methods: Using Tobacco Use Supplement to the Current Population Survey (TUS-CPS) 2002-2003 and 2010-2011 longitudinal cohorts, five smoking states are defined including daily-heavy, daily-light, non-daily, former and non-smoker. We quantified the changes between smoking states for the two longitudinal cohorts, and used a series of multivariable logistic regression models to examine the association of socio-demographic attributes and initial smoking states on smoking initiation, cessation, and relapse between waves within each cohort.
    Results: The prevalence of adult heavy smoking decreased from 9.9% (95% CI: 9.6%, 10.2%) in 2002 to 7.1% (95% CI: 6.9%, 7.4%) in 2010. Non-daily smokers were less likely to quit in the 2010-2011 cohort than the 2002-2003 cohort (37.0% vs. 44.9%). Gender, age group, smoker type, race and marital status exhibit similar patterns in terms of their association to the odds of initiation, cessation and relapse between the two cohorts, while education groups showed some inconsistent results between the two cohorts regarding the odds of cessation.
    Conclusions: Transitions between smoking states are complex and increasingly unstable, requiring a holistic, population-based perspective to understand the stocks and flows that ultimately dictate the public health impact of cigarette smoking behavior. This knowledge helps to identify groups in need of increased tobacco control prevention and intervention efforts.
    Language English
    Publishing date 2017-03-14
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 2194616-4
    ISSN 1617-9625 ; 2070-7266
    ISSN (online) 1617-9625
    ISSN 2070-7266
    DOI 10.1186/s12971-017-0121-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Trends in Characteristics of Patients Listed for Liver Transplantation Will Lead to Higher Rates of Waitlist Removal Due to Clinical Deterioration.

    Yi, Zinan / Mayorga, Maria E / Orman, Eric S / Wheeler, Stephanie B / Hayashi, Paul H / Barritt, A Sidney

    Transplantation

    2017  Volume 101, Issue 10, Page(s) 2368–2374

    Abstract: Background: Changes in the epidemiology of end-stage liver disease may lead to increased risk of dropout from the liver transplant waitlist. Anticipating the future of liver transplant waitlist characteristics is vital when considering organ allocation ... ...

    Abstract Background: Changes in the epidemiology of end-stage liver disease may lead to increased risk of dropout from the liver transplant waitlist. Anticipating the future of liver transplant waitlist characteristics is vital when considering organ allocation policy.
    Methods: We performed a discrete event simulation to forecast patient characteristics and rate of waitlist dropout. Estimates were simulated from 2015 to 2025. The model was informed by data from the Organ Procurement and Transplant Network, 2003 to 2014. National data are estimated along with forecasts for 2 regions.
    Results: Nonalcoholic steatohepatitis will increase from 18% of waitlist additions to 22% by 2025. Hepatitis C will fall from 30% to 21%. Listings over age 60 years will increase from 36% to 48%. The hazard of dropout will increase from 41% to 46% nationally. Wait times for transplant for patients listed with a Model for End-Stage Liver Disease (MELD) between 22 and 27 will double. Region 5, which transplants at relatively higher MELD scores, will experience an increase from 53% to 64% waitlist dropout. Region 11, which transplants at lower MELD scores, will have an increase in waitlist dropout from 30% to 44%.
    Conclusions: The liver transplant waitlist size will remain static over the next decade due to patient dropout. Liver transplant candidates will be older, more likely to have nonalcoholic steatohepatitis and will wait for transplantation longer even when listed at a competitive MELD score. There will continue to be significant heterogeneity among transplant regions where some patients will be more likely to drop out of the waitlist than receive a transplant.
    MeSH term(s) Adolescent ; Adult ; Age Factors ; Computer Simulation ; Disease Progression ; End Stage Liver Disease/diagnosis ; End Stage Liver Disease/mortality ; End Stage Liver Disease/surgery ; Female ; Forecasting ; Health Services Needs and Demand/trends ; Healthcare Disparities/trends ; Humans ; Liver Transplantation/trends ; Male ; Middle Aged ; Models, Theoretical ; Needs Assessment/trends ; Patient Dropouts ; Process Assessment (Health Care)/trends ; Risk Assessment ; Risk Factors ; Time Factors ; Tissue and Organ Procurement/trends ; United States/epidemiology ; Waiting Lists/mortality ; Young Adult
    Language English
    Publishing date 2017-08-29
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, U.S. Gov't, Non-P.H.S.
    ZDB-ID 208424-7
    ISSN 1534-6080 ; 0041-1337
    ISSN (online) 1534-6080
    ISSN 0041-1337
    DOI 10.1097/TP.0000000000001851
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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