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  1. Book ; Online ; E-Book: Transient receptor potential canonical classical channels and brain diseases

    Wang, YiZheng

    (Advances in experimental medicine and biology ; 976)

    2017  

    Author's details Yizheng Wang editor
    Series title Advances in experimental medicine and biology ; 976
    Collection
    Keywords Brain/Diseases ; TRP channels
    Subject code 616.80427
    Language English
    Size 1 Online Ressource (viii, 165 Seiten), Illustrationen, 26 cm
    Publisher Springer
    Publishing place Dordrecht
    Publishing country Netherlands
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019340910
    ISBN 978-94-024-1088-4 ; 978940241086 ; 94-024-1088-0 ; 9789402410860 ; 9402410864
    DOI 10.1007/978-94-024-1088-4
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book: Transient receptor potential canonical classical channels and brain diseases

    Wang, YiZheng

    (Advances in experimental medicine and biology ; 976)

    2017  

    Author's details Yizheng Wang editor
    Series title Advances in experimental medicine and biology ; 976
    Collection
    Keywords Brain/Diseases ; TRP channels
    Subject code 616.80427
    Language English
    Size viii, 165 Seiten, Illustrationen, 26 cm
    Publisher Springer
    Publishing place Dordrecht
    Publishing country Netherlands
    Document type Book
    HBZ-ID HT019340898
    ISBN 978-94-024-1086-0 ; 9789402410884 ; 94-024-1086-4 ; 9402410880
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Zs A 3192 -976- not available for loan Zeitschriften-Lesesaal

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  3. Article ; Online: Pipeline Multitype Artifact Recognition Method Based on Inception_Resnet _V2 Structure Improving SSD Network

    Yi Zheng

    Advances in Multimedia, Vol

    2022  Volume 2022

    Abstract: A fast recognition method for assembly line workpieces based on an improved SSD model is proposed to address the problems of low detection accuracy and lack of real-time performance when existing target detection models face small-scale targets and ... ...

    Abstract A fast recognition method for assembly line workpieces based on an improved SSD model is proposed to address the problems of low detection accuracy and lack of real-time performance when existing target detection models face small-scale targets and stacked targets. Based on the SSD network, the optimized Inception_Resnet _V2 structure is used to improve its feature extraction layer and enhance the extraction capability of the network for small-scale targets. The repulsion loss (Reploss) is used to optimize the loss function of the SSD network to solve the problem of stacked workpieces. The issue of difficult detection is improved. The robustness of the algorithm is enhanced. The experimental results show that the improved SSD target detection method improves the detection accuracy by 9.69% over the traditional SSD map. The detection speed meets the real-time requirements, which is a better balance of detection real time and accuracy requirements. The algorithm can recognize small-scale and stacked targets with higher category confidence, better algorithm robustness, and better recognition performance compared to the same type of target detection algorithms.
    Keywords Electronic computers. Computer science ; QA75.5-76.95
    Subject code 006
    Language English
    Publishing date 2022-01-01T00:00:00Z
    Publisher Hindawi Limited
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: VIDEO ANALYSIS AND 3D DETECTION SIMULATION OF JUMP SHOT PRECISION FOR BASKETBALL PLAYERS

    Yi Zheng

    Revista Brasileira de Medicina do Esporte, Vol 27, Iss spe2, Pp 104-

    2021  Volume 107

    Abstract: ABSTRACT With the rapid development and application of computer technology, the application of computer science knowledge in basketball is also more and more extensive. Based on genetic algorithm and the background subtraction method, video analysis and ... ...

    Abstract ABSTRACT With the rapid development and application of computer technology, the application of computer science knowledge in basketball is also more and more extensive. Based on genetic algorithm and the background subtraction method, video analysis and 3D detection simulation model of shot jump action precision were constructed in this study. According to the genetic algorithm search method, jump shot precision was analyzed, and the problems encountered in the actual shooting process of basketball players were studied and solved. The results show that this study is necessary and feasible.
    Keywords Algorithm ; Basketball ; Subtraction Technique ; Sports medicine ; RC1200-1245
    Language English
    Publishing date 2021-06-01T00:00:00Z
    Publisher Sociedade Brasileira de Medicina do Esporte
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Book: Rational drug design

    Zheng, Isabel Yi

    methods and protocols

    (Methods in molecular biology ; 928 ; Springer protocols)

    2012  

    Author's details ed. by Yi Zheng
    Series title Methods in molecular biology ; 928
    Springer protocols
    Collection
    Keywords Drug Design ; Laboratory Manuals
    Language English
    Size XI, 230 S. : Ill., graph. Darst., 27 cm
    Publisher Humana Press
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT017605460
    ISBN 978-1-62703-007-6 ; 1-62703-007-7 ; 9781627030083 ; 1627030085
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2013 A 404 available for loan (reading room) Lesesaal EG

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  6. Article ; Online: Mechanisms of Nanoscale Radiation Enhancement by Metal Nanoparticles

    Yi Zheng / Léon Sanche

    International Journal of Molecular Sciences, Vol 24, Iss 4697, p

    Role of Low Energy Electrons

    2023  Volume 4697

    Abstract: Metal nanoparticles are considered as highly promising radiosensitizers in cancer radiotherapy. Understanding their radiosensitization mechanisms is critical for future clinical applications. This review is focused on the initial energy deposition by ... ...

    Abstract Metal nanoparticles are considered as highly promising radiosensitizers in cancer radiotherapy. Understanding their radiosensitization mechanisms is critical for future clinical applications. This review is focused on the initial energy deposition by short-range Auger electrons; when high energy radiation is absorbed by gold nanoparticles (GNPs) located near vital biomolecules; such as DNA. Auger electrons and the subsequent production of secondary low energy electrons (LEEs) are responsible for most the ensuing chemical damage near such molecules. We highlight recent progress on DNA damage induced by the LEEs produced abundantly within about 100 nanometers from irradiated GNPs; and by those emitted by high energy electrons and X-rays incident on metal surfaces under differing atmospheric environments. LEEs strongly react within cells; mainly via bound breaking processes due to transient anion formation and dissociative electron attachment. The enhancement of damages induced in plasmid DNA by LEEs; with or without the binding of chemotherapeutic drugs; are explained by the fundamental mechanisms of LEE interactions with simple molecules and specific sites on nucleotides. We address the major challenge of metal nanoparticle and GNP radiosensitization; i.e., to deliver the maximum local dose of radiation to the most sensitive target of cancer cells (i.e., DNA). To achieve this goal the emitted electrons from the absorbed high energy radiation must be short range, and produce a large local density of LEEs, and the initial radiation must have the highest possible absorption coefficient compared to that of soft tissue (e.g., 20–80 keV X-rays).
    Keywords metal nanoparticles ; radiosensitization ; low-energy electrons ; DNA damage ; transient anions ; dissociative electron attachment ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Subject code 541
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

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  7. Article ; Online: Optimizing Green Strategy for Retired Electric Vehicle Battery Recycling

    Yi Zheng / Yaoqun Xu

    Sustainability, Vol 15, Iss 21, p

    An Evolutionary Game Theory Approach

    2023  Volume 15464

    Abstract: As the global new energy vehicle (NEV) industry rapidly expands, the disposal and recycling of end-of-life (EOL) power batteries have become imperative. Efficient closed-loop supply chain (CLSC) management, supported by well-designed regulations and ... ...

    Abstract As the global new energy vehicle (NEV) industry rapidly expands, the disposal and recycling of end-of-life (EOL) power batteries have become imperative. Efficient closed-loop supply chain (CLSC) management, supported by well-designed regulations and strategic investments, plays a crucial role in sustainable waste power battery recycling. In this study, an evolutionary game theory (EGT) methodology is used to construct a tripartite game model to investigate the interactions among manufacturers, recyclers, and the government to study the decision-making dynamics of green investments. In addition, numerical simulations are performed to evaluate the sensitivity of the relevant parameters on the stability of the evolution of the system. The results reveal that government green subsidies can stimulate early period investments in advanced recycling technologies. However, as the battery recycling industry matures, a ‘free-rider’ behavior emerges among enterprises, which can be mitigated through the imposition of a carbon tax. Eventually, as the industry reaches maturity, manufacturers and recyclers autonomously invest for enhanced profitability. This research provides valuable insights for government policy formulation, facilitating the formal recycling of retired batteries and fostering sustainability in the NEV sector.
    Keywords circular economy ; green investment ; power battery ; tripartite evolutionary game ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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    Inter-library loan at ZB MED

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  8. Article ; Online: Enhancing Operating Efficiency in China’s High-End Equipment Manufacturing Industry

    Yi Zheng / Min Luo

    Sustainability, Vol 15, Iss 8694, p

    Insights from Listed Enterprises

    2023  Volume 8694

    Abstract: The high-end equipment manufacturing industry is a strategic sector for China’s manufacturing transformation and upgrading. However, this industry is facing a series of challenges, such as insufficient innovation capabilities and poor business operations. ...

    Abstract The high-end equipment manufacturing industry is a strategic sector for China’s manufacturing transformation and upgrading. However, this industry is facing a series of challenges, such as insufficient innovation capabilities and poor business operations. This paper uses the super-efficiency SBM model to calculate the operating efficiency of listed companies in this industry from a micro perspective and conducts in-depth multi-angle analysis of their operating efficiency. Furthermore, Tobit regression is utilized to identify the factors that affect operating efficiency. The aim is to provide a pathway for companies in this industry to achieve efficiency maximization and sustainable development. The research shows that the average operating efficiency of high-end equipment manufacturing companies was around 0.7 from 2016 to 2021, and nearly 70% of companies were in a non-DEA efficient state. The operating efficiency of the intelligent manufacturing equipment industry is far higher than other industries, and the western region has great development potential. In addition to government subsidies, factors such as company age, equity concentration, regional GDP, and regional openness all have a positive impact on the operational efficiency of high-end equipment manufacturing companies. This paper combines the characteristics of the equipment manufacturing industry and analyzes their operating efficiency from multiple dimensions, providing decision support and pathways for the high-quality and efficient development of this industry.
    Keywords high-end equipment manufacturing ; operating efficiency ; super-efficiency SBM ; government subsidies ; Environmental effects of industries and plants ; TD194-195 ; Renewable energy sources ; TJ807-830 ; Environmental sciences ; GE1-350
    Subject code 670 ; 650
    Language English
    Publishing date 2023-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Selection of lubricant type and concentration for orodispersible tablets.

    Yi Zheng, Audrey / Teng Loh, Mahn / Wan Sia Heng, Paul / Wah Chan, Lai

    International journal of pharmaceutics

    2024  Volume 657, Page(s) 124190

    Abstract: Lubricants are essential for most tablet formulations as they assist powder flow, prevent adhesion to tableting tools and facilitate tablet ejection. Magnesium stearate (MgSt) is an effective lubricant but may compromise tablet strength and ... ...

    Abstract Lubricants are essential for most tablet formulations as they assist powder flow, prevent adhesion to tableting tools and facilitate tablet ejection. Magnesium stearate (MgSt) is an effective lubricant but may compromise tablet strength and disintegratability. In the design of orodispersible tablets, tablet strength and disintegratability are critical attributes of the dosage form. Hence, this study aimed to conduct an in-depth comparative study of MgSt with alternative lubricants, namely sodium lauryl sulphate (SLS), stearic acid (SA) and hydrogenated castor oil (HCO), for their effects on the tableting process as well as tablet properties. Powder blends were prepared with lactose, sodium starch glycolate or crospovidone as the disintegrant, and a lubricant at different concentrations. Angle of repose was determined for the mixtures. Comparative evaluation was carried out based on the ejection force, tensile strength, liquid penetration and disintegratability of the tablets produced. As the lubricant concentration increased, powder flow and tablet ejection improved. The lubrication efficiency generally decreased as follows: MgSt > HCO > SA > SLS. Despite its superior lubrication efficacy, MgSt is the only lubricant of four evaluated that reduced tablet tensile strength. Tablet disintegration time was strongly determined by tensile strength and liquid penetration, which were in turn affected by the lubricant type and concentration. All the above factors should be taken into consideration when deciding the type and concentration of lubricant for an orodispersible tablet formulation.
    Language English
    Publishing date 2024-05-01
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 428962-6
    ISSN 1873-3476 ; 0378-5173
    ISSN (online) 1873-3476
    ISSN 0378-5173
    DOI 10.1016/j.ijpharm.2024.124190
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1409: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  10. Article ; Online: Betting against pandemics: Ethical implications of the "COVID Claimania" in Taiwan, 2020-2022.

    Yeh, Ming-Jui / Liao, Yi-Zheng

    Developing world bioethics

    2023  

    Abstract: Among measures tackling the impacts of the COVID-19 pandemic, the selling of private insurance policies covering individual infection is overlooked by the ethics literature. To record the "COVID Claimania" in Taiwan and to assess its ethical implications, ...

    Abstract Among measures tackling the impacts of the COVID-19 pandemic, the selling of private insurance policies covering individual infection is overlooked by the ethics literature. To record the "COVID Claimania" in Taiwan and to assess its ethical implications, we collected 38 policies from 10 insurers sold between January 2020 and May 2022 and found that their risk calculation of the COVID-19 prevalence ranged from 0.5% to 11.08%. In reality, the prevalence by the end of 2022 was 37% in Taiwan. Selling private insurance policies is ethically problematic in three ways. First, it represents the insurance industry's irresponsible risk-taking profit-seeking behaviors. Second, it would jeopardize the effectiveness of the disease-prevention measures by inducing uncontrollable moral hazards. Third, it would expose the insurance companies to unbearable financial risks and cause substantial negative external impacts. The government should intervene in the private insurance market in preparation for future public health emergencies.
    Language English
    Publishing date 2023-03-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2049034-3
    ISSN 1471-8847 ; 1471-8731
    ISSN (online) 1471-8847
    ISSN 1471-8731
    DOI 10.1111/dewb.12398
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5461: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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