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  1. Article: Carney complex: a case report of bilateral breast myxoid fibroadenomas.

    Savva, Demetris / Vassiliou, Andreas / Theophanous, Elena / Loizou, Marios / Yiallourou, Anneza

    Case reports in plastic surgery & hand surgery

    2024  Volume 11, Issue 1, Page(s) 2347653

    Abstract: Carney complex is a rare autosomal dominant familiar multiple neoplasia syndrome combined with cardiocutaneous manifestations. Our report describes a Carney complex case with bilateral myxoid fibroadenomas that led to a bilateral mastectomy. An 18-year- ... ...

    Abstract Carney complex is a rare autosomal dominant familiar multiple neoplasia syndrome combined with cardiocutaneous manifestations. Our report describes a Carney complex case with bilateral myxoid fibroadenomas that led to a bilateral mastectomy. An 18-year-old female patient presented at our clinic with complaints of multiple palpable lumps in her breasts bilaterally. On physical examination the patient had also multiple pigmented lentiginous lesions on her face, body and her sclerae, blue nevi on her trunk and upper extremities and a round moon-shaped face. The diagnosis of Carney syndrome was decided upon imaging, biopsies and genetic analysis. The patient underwent a bilateral mastectomy as a prophylactic treatment plan with tissue expanders' placement. Breast myxomatosis due to Carney complex is a common characteristic in female patients. Prophylactic mastectomy must be considered as a therapeutic intervention in these cases since it provides a definite treatment, with minimal side effects and excellent outcomes.
    Language English
    Publishing date 2024-05-06
    Publishing country United States
    Document type Case Reports
    ISSN 2332-0885
    ISSN 2332-0885
    DOI 10.1080/23320885.2024.2347653
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  2. Article ; Online: Trends of Online Search of COVID-19 Related Terms in Cyprus.

    Anastasiou, Marios / Pantavou, Katerina / Yiallourou, Anneza / Bonovas, Stefanos / Nikolopoulos, Georgios K

    Epidemiolgia (Basel, Switzerland)

    2021  Volume 2, Issue 1, Page(s) 36–45

    Abstract: Knowledge of trends in web searches provides useful information for various purposes, including responses to public health emergencies. This work aims to analyze the popularity of internet search queries for Coronavirus Disease 2019 (COVID-19) and COVID- ... ...

    Abstract Knowledge of trends in web searches provides useful information for various purposes, including responses to public health emergencies. This work aims to analyze the popularity of internet search queries for Coronavirus Disease 2019 (COVID-19) and COVID-19 symptoms in Cyprus. Query data for the term Coronavirus were retrieved from Google Trends website between 19 January and 30 June 2020. The study focused on Cyprus and the four most populated cities: Nicosia, Limassol, Larnaca, and Paphos. COVID-19 symptoms including fever, cough, sore throat, shortness of breath, and myalgia were considered in the analysis. Daily and weekly search volumes were described, and their correlation with the evolution of the COVID-19 pandemic and important announcements or events were examined. Three periods of interest peaks were identified in Cyprus. The highest interest in COVID-19-related terms was found in the city of Paphos. The most popular symptoms were fever and cough, and the symptom with the highest increase in popularity was myalgia. At the beginning of the pandemic, the search volume of COVID-19 grew substantially when governments, major organizations, and high-profile figures, globally and locally, made important announcements regarding COVID-19. Health authorities in Cyprus and elsewhere could benefit from constantly monitoring the online interest of the population in order to get timely information that could be used in public health planning and response.
    Language English
    Publishing date 2021-01-20
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2673-3986
    ISSN (online) 2673-3986
    DOI 10.3390/epidemiologia2010004
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  3. Article ; Online: Beyond the physical risk: Psychosocial impact and coping in healthcare professionals during the COVID-19 pandemic.

    Fteropoulli, Theodora / Kalavana, Theano V / Yiallourou, Anneza / Karaiskakis, Marios / Koliou Mazeri, Maria / Vryonides, Stavros / Hadjioannou, Anna / Nikolopoulos, Georgios K

    Journal of clinical nursing

    2021  

    Abstract: Aims and objectives: This study aimed to examine the psychosocial impact and identify risk factors for poor psychosocial outcomes in healthcare professionals during the Coronavirus disease 2019 (COVID-19) pandemic in Cyprus.: Background: Healthcare ... ...

    Abstract Aims and objectives: This study aimed to examine the psychosocial impact and identify risk factors for poor psychosocial outcomes in healthcare professionals during the Coronavirus disease 2019 (COVID-19) pandemic in Cyprus.
    Background: Healthcare professionals are in the forefront of the COVID-19 pandemic facing an unprecedented global health crisis, which can have consequences on their psychosocial health. There is a need to identify risk factors for poor psychosocial outcomes to inform the design of tailored psychological interventions.
    Design: Cross-sectional online study.
    Methods: A total of 1071 healthcare professionals completed self-report questionnaires. Measures included sociodemographic information, COVID-19-related characteristics, quality of life (Brief World Health Organization Quality of Life; WHOQOL-Bref), anxiety (Generalized Anxiety Disorder-7; GAD-7), depression (Patient Health Questionnaire-8; PHQ-8), occupational burnout (Copenhagen Burnout Inventory; CBI), and coping (Brief Coping Orientation to Problems Experienced; Brief COPE). This article follows the STROBE reporting guidelines.
    Results: The prevalence of moderate to severe anxiety and clinically significant depression was 27.6% and 26.8%, respectively. Significant risk factors for poor psychological outcomes included being female, being a nurse or doctor (vs non-medical professional), working in frontline units (inpatient, intensive care), perceptions of inadequate workplace preparation to deal with the pandemic, and using avoidance coping. Depression and occupational burnout were significant risk factors for poor quality of life.
    Conclusion: The findings suggest several individual, psychosocial, and organisational risk factors for the adverse psychological outcomes observed in healthcare professionals during the COVID-19 pandemic.
    Relevance to clinical practice: This study highlights the urgent need for screening for anxiety and depression and psychological interventions to combat an imminent mental health crisis in healthcare professionals during the COVID-19 pandemic. Pandemic response protocols and public health initiatives aiming to improve and prevent mental health problems in healthcare professionals during the current and future health crises, need to account for the various factors at play.
    Language English
    Publishing date 2021-07-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 1159483-4
    ISSN 1365-2702 ; 0962-1067 ; 1752-9816
    ISSN (online) 1365-2702
    ISSN 0962-1067 ; 1752-9816
    DOI 10.1111/jocn.15938
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    Zs.A 3764: Show issues Location:
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  4. Article ; Online: State of knowledge of human papillomavirus (HPV), HPV vaccine and testing: a cross-sectional study among female university students in Cyprus.

    Charalambous, Ioanna / Ioannou, Gavriella / Nikolaou, Stefania / Theologou, Rafaella / Yiallourou, Anneza / Papatheodorou, Stefania / Pantavou, Katerina G / Nikolopoulos, Georgios K

    Women & health

    2019  Volume 60, Issue 1, Page(s) 26–42

    Abstract: This study aimed to evaluate human papillomavirus (HPV)-related knowledge of women aged 18-25 years and estimate the reported uptake of HPV vaccine and testing. A cross-sectional study was conducted among female students of the University of Cyprus ... ...

    Abstract This study aimed to evaluate human papillomavirus (HPV)-related knowledge of women aged 18-25 years and estimate the reported uptake of HPV vaccine and testing. A cross-sectional study was conducted among female students of the University of Cyprus between March and April 2017. The participants self-completed a questionnaire, which consisted of 37 items on demographics, general HPV-related knowledge, and HPV vaccination and testing. In total, 283 young females (mean age: 19.7 ± 1.5 years) took part in the study. Of these, about half (53.7%) reported that they were aware of HPV; one-third (30.7%) reported having been vaccinated; 38.8% had been informed of the recent introduction of the HPV vaccine in the National Immunization Schedule in Cyprus, while 14.3% reported a previous Pap-test and 3.4% a previous HPV DNA test. The mean Overall Knowledge Index (max: 25 correct answers) was 6.1 (±3.8) and was positively associated with the reported uptake of the HPV vaccine (adjusted Odds ratio: 1.14, 95% Confidence Interval (CI): 1.04-1.24). Knowledge about HPV has to be improved as it is associated with increased reported rates of HPV vaccination.
    MeSH term(s) Adolescent ; Adult ; Cross-Sectional Studies ; Cyprus ; Female ; Health Knowledge, Attitudes, Practice ; Humans ; Papanicolaou Test/statistics & numerical data ; Papillomaviridae ; Papillomavirus Infections/diagnosis ; Papillomavirus Infections/prevention & control ; Papillomavirus Vaccines ; Students/statistics & numerical data ; Surveys and Questionnaires ; Universities ; Uterine Cervical Neoplasms/prevention & control ; Vaccination/statistics & numerical data ; Young Adult
    Chemical Substances Papillomavirus Vaccines
    Language English
    Publishing date 2019-05-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603396-9
    ISSN 1541-0331 ; 0363-0242
    ISSN (online) 1541-0331
    ISSN 0363-0242
    DOI 10.1080/03630242.2019.1610825
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    Zs.B 2265: Show issues Location:
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  5. Article: Immunohistochemical expression patterns of S100, synaptophysin, chromogranin A and neuron specific enolase in predicting malignant behaviour in paragangliomas.

    Nastos, Constantinos / Yiallourou, Anneza / Kotsis, Thomas / Mizamtsidi, Maria / Delaportas, Dionysios / Kondi-Pafiti, Agathi / Polymeneas, George

    Journal of B.U.ON. : official journal of the Balkan Union of Oncology

    2018  Volume 23, Issue 5, Page(s) 1540–1545

    Abstract: Purpose: The purpose of this study was to evaluate the role of immunohistochemical markers in the prediction of malignancy in paragangliomas.: Methods: Our institute's patient records between 1990-2012 were retrieved in order to identify patients who ...

    Abstract Purpose: The purpose of this study was to evaluate the role of immunohistochemical markers in the prediction of malignancy in paragangliomas.
    Methods: Our institute's patient records between 1990-2012 were retrieved in order to identify patients who were treated for paragangliomas. Size and location of the tumour, existence of concurrent metastatic disease, patient demographics and survival were recorded. Haematoxylin-eosin stained slides were reviewed and all tumours were stained specifically for neuron specific enolase (NSE), chromogranin, synaptophysin and S100 protein positivity. Positivity and expression patterns of the above markers were evaluated and compared between malignant and benign tumours. Malignant behaviour was defined when patient had concurrent or subsequent lymph node involvement, local recurrence and/or metastases.
    Results: A total of 22 patients with a diagnosis of paraganglioma were treated in our institutes. Female to male ratio was 1.75: 1. The mean age was 43.5 and 51.6 years for women and men, respectively. In 5 patients the tumors had malignant clinical behavior. Their mean size was 3.65 cm for benign and 4.56 cm for malignant neoplasms. NSE expression was diffuse in 47.1% and 0% for benign and malignant tumors, respectively (p=0.10). S100 expression in the periphery of the tumour was typical in 88.2% and 0% for benign and malignant tumors, respectively (p<0.001).
    Conclusion: Immunohistochemical profile from the combination of NSE, synaptophysin chromogranin and S100 staining patterns can serve as a cheap and valuable tool for correctly distinguishing between malignant and benign paragangliomas with high diagnostic accuracy.
    MeSH term(s) Biomarkers, Tumor/biosynthesis ; Chromogranin A/biosynthesis ; Female ; Humans ; Immunohistochemistry/methods ; Male ; Middle Aged ; Paraganglioma/metabolism ; Paraganglioma/pathology ; Phosphopyruvate Hydratase/biosynthesis ; S100 Proteins/biosynthesis ; Synaptophysin/biosynthesis
    Chemical Substances Biomarkers, Tumor ; CHGA protein, human ; Chromogranin A ; S100 Proteins ; SYP protein, human ; Synaptophysin ; Phosphopyruvate Hydratase (EC 4.2.1.11)
    Language English
    Publishing date 2018-12-20
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 2040386-0
    ISSN 2241-6293 ; 1107-0625
    ISSN (online) 2241-6293
    ISSN 1107-0625
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    Zs.A 5438: Show issues Location:
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  6. Article: Clinicopathological features and management of hepatic vascular tumors. A 20-year experience in a Greek University Hospital.

    Theodosopoulos, T / Dellaportas, D / Tsangkas, A / Tsangkas, N / Psychogiou, V / Yiallourou, A / Polymeneas, G / Kondi-Pafiti, A

    Journal of B.U.ON. : official journal of the Balkan Union of Oncology

    2013  Volume 18, Issue 4, Page(s) 1026–1031

    Abstract: Purpose: The aim of this study was to review the clinical features, diagnostic modalities, treatment options and pathological characteristics of various types of hepatic vascular tumors treated in our Institution over the last 20 years.: Methods: ... ...

    Abstract Purpose: The aim of this study was to review the clinical features, diagnostic modalities, treatment options and pathological characteristics of various types of hepatic vascular tumors treated in our Institution over the last 20 years.
    Methods: From 1991 to 2011, 761 cases of various hepatic lesions, benign and malignant, were surgically treated in our hospital. Among these, 56 (7.35%) hepatectomy specimens referred to vascular tumors. The records of these patients were retrieved and demographics , tumor characteristics, treatment, and actuarial survival were analyzed. The various therapeutic procedures, postoperative complications, follow-up data and the pre-and postoperative diagnostic difficulties were registered and analyzed.
    Results: Pathological examination showed: hepatic hemangiomas in 35 (62.5%) patients (80% females), hepatic angiosarcomas in 7 patients (12.5%; males 71.4%), hepatic epithelioid hemangioendotheliomas in 9 (16%; females 50%) and hepatic angiomyolipomas in 5 patients (9%; females 60%).
    Conclusions: Vascular tumors of the liver comprise a heterogeneous group of neoplasms, benign, malignant and of intermediate degree of malignant behavior. These lesions can create great diagnostic difficulties, pre- and postoperative considerations, but the correct pathological diagnosis and classification of vascular hepatic tumors are most of the times mandatory in order to choose the proper therapeutic actions.
    MeSH term(s) Adult ; Female ; Greece ; Hemangioendothelioma, Epithelioid/pathology ; Hemangioendothelioma, Epithelioid/surgery ; Hemangioma/pathology ; Hemangioma/surgery ; Hemangiosarcoma/pathology ; Hemangiosarcoma/surgery ; Hepatectomy/adverse effects ; Hepatectomy/mortality ; Hospitals, University ; Humans ; Liver Neoplasms/mortality ; Liver Neoplasms/pathology ; Liver Neoplasms/surgery ; Male ; Middle Aged ; Neoplasms, Vascular Tissue/mortality ; Neoplasms, Vascular Tissue/pathology ; Neoplasms, Vascular Tissue/surgery ; Retrospective Studies ; Time Factors ; Treatment Outcome
    Language English
    Publishing date 2013-10
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 2040386-0
    ISSN 2241-6293 ; 1107-0625
    ISSN (online) 2241-6293
    ISSN 1107-0625
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    Zs.A 5438: Show issues Location:
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  7. Article ; Online: The impact of peri-operative anti-TNF treatment on anastomosis-related complications in Crohn's disease patients. A critical review.

    Papaconstantinou, Ioannis / Zeglinas, Christos / Gazouli, Maria / Nastos, Konstantinos / Yiallourou, Anneza / Papalois, Apostolos / Tzathas, Charalambos

    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

    2014  Volume 18, Issue 6, Page(s) 1216–1224

    Abstract: Introduction: Tumor necrosis factor (TNF)α is a cytokine exerting pleiotropic effects on critical cell functions and, most importantly, is the main regulator of pro-inflammatory cytokine production and a key player in the pathophysiology of numerous ... ...

    Abstract Introduction: Tumor necrosis factor (TNF)α is a cytokine exerting pleiotropic effects on critical cell functions and, most importantly, is the main regulator of pro-inflammatory cytokine production and a key player in the pathophysiology of numerous autoimmune diseases, including Crohn's disease.
    Methods: TNFα became a therapeutic target and TNFα blocking agents are currently used in the treatment of inflammatory diseases. Beyond the therapeutic benefits deriving from TNFα neutralization, amendments in the cellular functions of the immune system may as well induce potent immunosuppressive effects. An attenuated immune response may compromise the intestinal healing ability, thus leading to weaker anastomosis and increased risk of anastomotic leak and septic complications.
    Results: This hypothesis raises great concerns about the safety of perioperative administration of anti-TNF and has been the endpoint of numerous studies.
    Conclusion: The aim of this review is to critically evaluate the evidence regarding the role of TNFα in anastomosis related complications after abdominal surgery in Crohn's disease patients.
    MeSH term(s) Abdominal Abscess/etiology ; Anastomosis, Surgical/adverse effects ; Anastomotic Leak/etiology ; Anti-Inflammatory Agents, Non-Steroidal/adverse effects ; Antibodies, Monoclonal/adverse effects ; Crohn Disease/drug therapy ; Crohn Disease/surgery ; Fistula/etiology ; Humans ; Infliximab ; Perioperative Care ; Reoperation ; Tumor Necrosis Factor-alpha/antagonists & inhibitors
    Chemical Substances Anti-Inflammatory Agents, Non-Steroidal ; Antibodies, Monoclonal ; Tumor Necrosis Factor-alpha ; Infliximab (B72HH48FLU)
    Language English
    Publishing date 2014-03-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2012365-6
    ISSN 1873-4626 ; 1934-3213 ; 1091-255X
    ISSN (online) 1873-4626 ; 1934-3213
    ISSN 1091-255X
    DOI 10.1007/s11605-014-2487-3
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    Zs.A 5207: Show issues Location:
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    Zs.MO 354: Show issues

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  8. Article: Results of salvage abdominoperineal resection after failed chemoradiation therapy for epidermoid anal canal carcinoma: Retrospective analysis at a single institution.

    Papaconstantinou, I / Yiallourou, A / Theodosopoulos, T / Samanides, L / Smyrniotis, V / Fotopoulos, A / Polymeneas, G / Gennatas, C / Voros, D

    Journal of B.U.ON. : official journal of the Balkan Union of Oncology

    2011  Volume 16, Issue 4, Page(s) 697–700

    Abstract: Purpose: The standard therapeutic approach to epidermoid anal canal cancer consists of combined radiation therapy and chemotherapy. Although disease control has been reported to have excellent results, as many as 40% of patients will develop ... ...

    Abstract Purpose: The standard therapeutic approach to epidermoid anal canal cancer consists of combined radiation therapy and chemotherapy. Although disease control has been reported to have excellent results, as many as 40% of patients will develop locoregional disease progression. The treatment of choice for patients with persistent (PD) or recurrent disease (RD) is salvage abdominoperineal resection (APR). The purpose of this study was to review our experience with salvage surgery in this group of patients.
    Methods: The medical records of all patients with epidermoid anal canal cancer treated from 1997 to 2010 in our department were retrospectively reviewed. Nine patients who presented with persistent or locally recurrent anal canal cancer were subjected to salvage APR. Before surgery, all of the patients had received chemoradiation therapy (CRT).
    Results: There were 9 patients (7 women, 2 men) with a median age of 59 years (range 40-79). Six patients underwent radical salvage APR for persistent disease and 3 patients for recurrent disease. There were no deaths attributable to operation. The median follow-up time was 31.75 months (range 3-108) after salvage surgery. Two patients died of disease progression, with a median survival time of 24 months (range 12-36). At the time of last follow-up, 6 patients were alive without evidence of recurrent disease, and one patient was lost to follow-up. The median follow-up time for survivors was 34.3 months (range 3-108).
    Conclusion: Long-term survival can be achieved in the majority of patients who undergo radical salvage APR after failed CRT for epidermoid carcinoma of the anal canal.
    MeSH term(s) Abdomen/pathology ; Abdomen/surgery ; Adult ; Aged ; Anus Neoplasms/radiotherapy ; Anus Neoplasms/surgery ; Anus Neoplasms/therapy ; Carcinoma, Squamous Cell/radiotherapy ; Carcinoma, Squamous Cell/surgery ; Carcinoma, Squamous Cell/therapy ; Chemoradiotherapy ; Female ; Humans ; Male ; Middle Aged ; Perineum/pathology ; Perineum/surgery ; Retrospective Studies ; Salvage Therapy/methods ; Survival Rate ; Treatment Failure
    Language English
    Publishing date 2011-10
    Publishing country Greece
    Document type Journal Article
    ZDB-ID 2040386-0
    ISSN 2241-6293 ; 1107-0625
    ISSN (online) 2241-6293
    ISSN 1107-0625
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  9. Article ; Online: Ovarian vein thrombosis mimicking acute abdomen: a case report and literature review.

    Arkadopoulos, Nikolaos / Dellaportas, Dionysios / Yiallourou, Anneza / Koureas, Andreas / Voros, Dionysios

    World journal of emergency surgery : WJES

    2011  Volume 6, Issue 1, Page(s) 45

    Abstract: Background: Ovarian vein thrombosis (OVT) is a rare, but serious condition that affects mostly postpartum women. A high index of suspicion is required in order to diagnose this unusual cause of abdominal pain.: Case presentation: A 19-year-old woman ... ...

    Abstract Background: Ovarian vein thrombosis (OVT) is a rare, but serious condition that affects mostly postpartum women. A high index of suspicion is required in order to diagnose this unusual cause of abdominal pain.
    Case presentation: A 19-year-old woman at three days postpartum was admitted to our hospital because of severe right lower quandrant abdominal pain and fever 38.5'C. Physical examination revealed an acutely ill patient and right lower quadrant tenderness with positive rebound and Giordano signs. The patient underwent appendectomy which proved to be negative for acute appendicitis. Postoperatively fever and pain persisted and abdominal CT-scan with intravenous contrast agent demonstrated a thrombosed right ovarian vein. The patient was initiated on low-molecular weight heparin (LMWH) and antibiotic treatment and a month later a new abdominal CT-scan showed a patent right ovarian vein.
    Discussion: Pathophysiologically, OVT is explained by Virchow's triad, because pregnancy is associated with a hypercoagulable state, venous stasis due to compression of the inferior vena cava by the uterus and endothelial trauma during delivery or from local inflammation. Common symptoms and signs of OVT include lower abdomen or flank pain, fever and leukocytosis usually within the first ten days after delivery. The reported incidence of OVT ranges 0,05-0,18% of pregnancies and in most cases the right ovarian vein is the one affected. Anticoagulation and antibiotics is the mainstay of treatment of OVT. Complications of OVT include sepsis, extension of the thrombus to the inferior vena cava and renal veins, and pulmonary embolism. The incidence of pulmonary embolism is reported to be 13.2% and represents the main source of mortality due to OVT.
    Conclusions: OVT is a rare condition, usually in the postpartum period. A high index of suspicion is required for the prompt diagnosis and management especially in cases that mimic acute abdomen.
    Language English
    Publishing date 2011-12-23
    Publishing country England
    Document type Journal Article
    ISSN 1749-7922
    ISSN (online) 1749-7922
    DOI 10.1186/1749-7922-6-45
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  10. Article: Multifocal retroperitoneal sarcoma.

    Theodosopoulos, Theodosios / Dellaportas, Dionysios / Psychogiou, Vasiliki / Yiallourou, Anneza / Polymeneas, George / Gkiokas, Georgios / Voros, Dionysios

    Case reports in surgery

    2013  Volume 2013, Page(s) 763702

    Abstract: Introduction. Retroperitoneal sarcomas comprise a small proportion of all soft tissue sarcomas, and multiple factors influence their clinical behavior. Histopathological type and grade as well as complete surgical resection especially on the first ... ...

    Abstract Introduction. Retroperitoneal sarcomas comprise a small proportion of all soft tissue sarcomas, and multiple factors influence their clinical behavior. Histopathological type and grade as well as complete surgical resection especially on the first operative attempt are well recognized as the main prognostic factors. Multifocality is another prognostic factor, which compromises therapy and finally makes prognosis worse due to multiple adverse implications. Case Presentation. A rare case of a 65-year-old male patient suffering from a multifocal retroperitoneal liposarcoma successfully treated in our hospital is presented herein. Discussion. Also, general considerations for these tumors are discussed, and especially multifocality is underlined as an ominous sign of retroperitoneal sarcomas behavior. Despite multifocality, once again complete surgical excision remains the mainstay of treatment of these patients, as long as further systemic and local therapies do not provide durable results.
    Language English
    Publishing date 2013-05-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2657697-1
    ISSN 2090-6919 ; 2090-6900
    ISSN (online) 2090-6919
    ISSN 2090-6900
    DOI 10.1155/2013/763702
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