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  1. Article ; Online: Wavelet Transform Feature Enhancement for Semantic Segmentation of Remote Sensing Images

    Yifan Li / Ziqian Liu / Junli Yang / Haopeng Zhang

    Remote Sensing, Vol 15, Iss 24, p

    2023  Volume 5644

    Abstract: With developments in deep learning, semantic segmentation of remote sensing images has made great progress. Currently, mainstream methods are based on convolutional neural networks (CNNs) or vision transformers. However, these methods are not very ... ...

    Abstract With developments in deep learning, semantic segmentation of remote sensing images has made great progress. Currently, mainstream methods are based on convolutional neural networks (CNNs) or vision transformers. However, these methods are not very effective in extracting features from remote sensing images, which are usually of high resolution with plenty of detail. Operations including downsampling will cause the loss of such features. To address this problem, we propose a novel module called Hierarchical Wavelet Feature Enhancement (WFE). The WFE module involves three sequential steps: (1) performing multi-scale decomposition of an input image based on the discrete wavelet transform; (2) enhancing the high-frequency sub-bands of the input image; and (3) feeding them back to the corresponding layers of the network. Our module can be easily integrated into various existing CNNs and transformers, and does not require additional pre-training. We conducted experiments on the ISPRS Potsdam and ISPRS Vaihingen datasets, with results showing that our method improves the benchmarks of CNNs and transformers while performing little additional computation.
    Keywords discrete wavelet transform ; remote sensing images ; feature enhancement ; semantic segmentation ; Science ; Q
    Subject code 000 ; 004
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Investigation of the Influence Area of the Excavation of a Double-Line Highway Tunnel under an Existing Railway Tunnel

    Yifan Li / Changfu Huang / Hongjian Lu / Chao Mou

    Applied Sciences, Vol 14, Iss 1, p

    2023  Volume 290

    Abstract: The research on the impact of the excavation of underpass tunnels has already had certain results, but there is a lack of research cases of double-line highway tunnels with oblique angles under the existing railway tunnels, especially the method of ... ...

    Abstract The research on the impact of the excavation of underpass tunnels has already had certain results, but there is a lack of research cases of double-line highway tunnels with oblique angles under the existing railway tunnels, especially the method of determining the area of the impact of the dynamic and static loads of new tunnels and existing trains, which can be enriched by considering them at the same time. This paper, is based on the tunnel project of the new double-line Shiqian highway tunnel with oblique angles under the Hurong railway in Wanshoushan. By constructing a three-dimensional finite element model and simulating the application of static tunnel excavation load, dynamic blasting load, and dynamic train operation load of the existing tunnel, the overall displacement of the existing tunnel and the settlement value of the bottom plate of the track surface by the static tunnel excavation load were analyzed. Then, the stresses, vibration speeds, and displacements of the tunnel due to the dynamic blasting loads and the dynamic train operation loads were obtained. The results show that the area of influence of the static loads of the new tunnel excavation on the existing tunnel is divided into three types of perturbations presenting strong, weak, and slight; the area affected by the blasting dynamic load of new tunnel excavation is a circular domain with the datum point in the tunnel section as the center; the area affected by the dynamic load of train operation in the existing tunnel is an ellipse with the center of the track surface of the existing tunnel as the datum; and there is an anomalous shape in the area affected by the blasting dynamic load of new tunnel excavation and the area affected by the dynamic load of the train operation in the existing tunnel.
    Keywords double-line highway tunnel ; oblique passing under ; area of influence ; numerical simulation ; tunnel dynamics and static loads ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
    Subject code 621 ; 690
    Language English
    Publishing date 2023-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: A Novel Quantitative Approach to the Spatial Configuration of Urban Streets Based on Local Wind Environment

    Huimin Ji / Yifan Li / Juan Li / Wowo Ding

    Land, Vol 12, Iss 12, p

    2023  Volume 2102

    Abstract: The urban street is an important part of the urban form and serves as the primary medium for public activities within cities. The morphological characteristics of urban street space not only influence people’s spatial experience but also have an impact ... ...

    Abstract The urban street is an important part of the urban form and serves as the primary medium for public activities within cities. The morphological characteristics of urban street space not only influence people’s spatial experience but also have an impact on the quality of the physical environment, such as the wind environment. Numerous scholars have studied the wind environment of streets with different morphological characteristics using abstract and simplified street models, uncovering certain relationships between specific morphological features and airflow patterns. However, due to the significant disparity between simplified models and reality, researchers have attempted to develop models applicable to the complex characteristics of urban street space, with the aim of exploring the relationship between street spatial features and airflow characteristics. This study explores a method to quantify the complex spatial characteristics of urban streets, using a series of parameters to describe the streets, such as average width, proportion of secondary interfaces, and proportion of opening length. Streets with different spatial characteristics in the centre of Nanjing are selected and quantified. A comparison is conducted between the parameters representing street spatial morphology and the simulation results of the wind environment in the area, aiming to assess the effectiveness of these parameter values. The results demonstrate that complex urban spaces can still be effectively represented through parameterization and confirm the validity of our quantitative representation of complex street spatial characteristics. The results could serve as a reference for urban design and urban construction.
    Keywords urban morphology ; street spatial configuration ; quantitative approach ; local wind environment ; relationship analysis ; Agriculture ; S
    Subject code 720
    Language English
    Publishing date 2023-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: SNORD3A acts as a potential prognostic and therapeutic biomarker in gastric cancer

    Qi Wang / Yifan Li / Xiaoqiang Niu / Chengjiang Zhang / Jun Zhang / Jiaqing Cao / Lidong Wu

    Electronic Journal of Biotechnology, Vol 67, Iss , Pp 1-

    2024  Volume 12

    Abstract: Background: Although SNORD3A has been implicated in cancer progression, its specific roles and underlying mechanisms in gastric cancer (GC) remain poorly understood. We analysed SNORD3A expression using TCGA data and evaluated patient survival via Kaplan‒ ...

    Abstract Background: Although SNORD3A has been implicated in cancer progression, its specific roles and underlying mechanisms in gastric cancer (GC) remain poorly understood. We analysed SNORD3A expression using TCGA data and evaluated patient survival via Kaplan‒Meier curves. Additionally, we conducted GO-KEGG enrichment analysis to identify relevant biological processes and signaling pathways, while ssGSEA was used to assess the correlation between SNORD3A and cancer immune infiltrates. Furthermore, we explored the relationship between SNORD3A and immunotherapy response through TIDE. We verified SNORD3A expression using real-time qPCR and assessed cell proliferation, migration, and invasion via CCK8 and Transwell migration and invasion assays. Results: Our results revealed that SNORD3A was significantly upregulated in GC, with high expression correlating with poor survival. SNORD3A and related genes were primarily enriched in the insulin/insulin-related growth factor signaling pathway. We also observed negative associations between SNORD3A expression and several immune cells, including activated dendritic cells, CD56bright natural killer cells, central memory CD8 T cells, effector memory CD8 T cells, effector memory CD4 T cells, eosinophils, immature dendritic cells, macrophages, mast cells, MDSCs, memory B cells, monocytes, neutrophil cells, plasmacytoid dendritic cells, regulatory T cells, and T follicular helper cells. High SNORD3A expression also correlated with a poorer response to immunotherapy. Finally, inhibition of SNORD3A suppressed cell proliferation, migration, and invasion. Conclusions: Our findings suggest that SNORD3A plays a catalytic role in the proliferation, migration and invasiveness of GC and may have potential as a diagnostic biomarker and therapeutic target for GC.How to cite: Wang Q, Li Y, Niu X, et al. SNORD3A acts as a potential prognostic and therapeutic biomarker in gastric cancer. Electron J Biotechnol 2023; 67. https://doi.org/10.1016/j.ejbt.2023.08.004.
    Keywords Gastric cancer ; Gastric cancer invasiveness ; Gastric cancer migration ; Gastric cancer proliferation ; GO-KEGG analysis ; Kaplan-Meier curves ; Biotechnology ; TP248.13-248.65 ; Biology (General) ; QH301-705.5
    Subject code 610
    Language English
    Publishing date 2024-01-01T00:00:00Z
    Publisher Elsevier
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Kinetic Analysis of Pyrolysis Reaction of Hydrogen-Containing Low Rank Coals Based on Thermogravimetric Method

    Qiyuan Mi / Bin Li / Yifan Li / Yue Ma / Ruimeng Shi

    Processes, Vol 11, Iss 706, p

    2023  Volume 706

    Abstract: Based on the combined technology of thermogravimetric analysis-mass spectrometry (TG-MS), the non isothermal kinetic of two low rank coals with high hydrogen content and the release characteristics of H 2 in volatiles were explored. The effect of coal ... ...

    Abstract Based on the combined technology of thermogravimetric analysis-mass spectrometry (TG-MS), the non isothermal kinetic of two low rank coals with high hydrogen content and the release characteristics of H 2 in volatiles were explored. The effect of coal species and coal particle size on pyrolysis was studied. The CR (Coats-Redfern) method and the DAEM (Distributed activation energy model) method were used to construct the pyrolysis kinetic model by dividing temperature stages, and the results showed that the mechanisms of pyrolysis process of lower rank coals were mainly 3-D diffusion (G-B) and Growth of nucleation (Avrami-Erofeev, n = 1/3). The use of the DAEM method made up for the shortcomings of the CR method in calculating the activation energy, and the analysis of coal pyrolysis kinetics was more comprehensive. The higher the volatile content the coal contained, the lower activation energy the pyrolysis process would require. The larger the particle size of the coal was, the higher activation energy the pyrolysis process would need. The release law of H 2 in low rank coal during the pyrolysis process was analyzed by mass spectrometry, and results were presented: the first peak occurs at 500 °C and the second at 750 °C, which was mainly generated by the condensation and dehydrogenation reactions of aromatic compounds.
    Keywords low rank coal ; volatiles ; pyrolysis kinetics ; DAEM model ; Chemical technology ; TP1-1185 ; Chemistry ; QD1-999
    Subject code 660
    Language English
    Publishing date 2023-02-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Spatiotemporal Pattern of Carbon Compensation Potential and Network Association in Urban Agglomerations in the Yellow River Basin

    Haihong Song / Yifan Li / Liyuan Gu / Jingnan Tang / Xin Zhang

    ISPRS International Journal of Geo-Information, Vol 12, Iss 10, p

    2023  Volume 435

    Abstract: The Yellow River Basin is an important energy base and economic belt in China, but its water resources are scarce, its ecology is fragile, and the task of achieving the goal of carbon peak and carbon neutrality is arduous. Carbon compensation potential ... ...

    Abstract The Yellow River Basin is an important energy base and economic belt in China, but its water resources are scarce, its ecology is fragile, and the task of achieving the goal of carbon peak and carbon neutrality is arduous. Carbon compensation potential can also be used to study the path to achieving carbon neutrality, which can clarify the potential of one region’s carbon sink surplus to be compensated to the other areas. Still, there needs to be more research on the carbon compensation potential of the Yellow River Basin. Therefore, this study calculated the carbon compensation potential using the β convergence test and parameter comparison method. With the help of spatial measurement tools such as GIS, GeoDa, Stata, and social network analysis methods, the spatiotemporal pattern and network structure of the carbon compensation potential in the Yellow River Basin were studied from the perspective of urban agglomeration. The results demonstrate the following: (1) The overall carbon compensation rate of the YRB showed a downward trend from 2005 to 2019, falling by 0.94, and the specific pattern was “high in the northwest and low in the southeast”. The spatial distribution is roughly spread along the east–west axis, and the distribution axis and the center of gravity keep shifting to the northwest. It also showed a weak divergence and a bifurcation trend. (2) The carbon compensation rate in the YRB passed the spatial correlation and β convergence tests, demonstrating the existence of spatial correlation and a “catch-up effect” among cities. (3) The overall distribution pattern of the carbon compensation potential in the YRB is a “low in the west and high in the east” pattern, and its value increased by 8.86% during the sampled period. (4) The network correlation of carbon compensation potential in the YRB has been significantly enhanced, with the downstream region being more connected than the upstream region. (5) The Shandong Peninsula Urban Agglomeration has the largest network center, followed by the Central ...
    Keywords carbon compensation potential ; spatiotemporal pattern ; network association ; urban agglomeration ; Yellow River basin ; β convergence test ; Geography (General) ; G1-922
    Subject code 550
    Language English
    Publishing date 2023-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Glutathione S-Transferase May Contribute to the Detoxification of (S)-(−)-Palasonin in Plutella xylostella (L.) via Direct Metabolism

    Qiqi Fan / Jiyuan Liu / Yifan Li / Yalin Zhang

    Insects, Vol 13, Iss 989, p

    2022  Volume 989

    Abstract: The control of P. xylostella primarily involves chemical insecticides, but overuse has brought about many negative effects. Our previous study reported that (S)-(−)-palasonin (PLN) is a plant-derived active substance with significant insecticidal ... ...

    Abstract The control of P. xylostella primarily involves chemical insecticides, but overuse has brought about many negative effects. Our previous study reported that (S)-(−)-palasonin (PLN) is a plant-derived active substance with significant insecticidal activity against P. xylostella . However, we noticed a possible cross-resistance between (S)-(−)-palasonin and other insecticides which may be related to metabolic detoxification. In order to further explore the detoxification effect of detoxification enzymes on (S)-(−)-palasonin in P. xylostella , the effects of (S)-(−)-palasonin on enzyme activity and transcription level were determined, and the detoxification and metabolism of GSTs on (S)-(−)-palasonin were studied by in vitro inhibition and metabolism experiments. During this study, GST enzyme activity was significantly increased in P. xylostella after (S)-(−)-palasonin treatment. The expression levels of 19 GSTs genes were significantly increased whereas the expression levels of 1 gene decreased. Furthermore, (S)-(−)-palasonin is shown to be stabilized with GSTs and metabolized GSTs (GSTd1, GSTd2, GSTs1 and GSTs2) in vitro, with the highest metabolic rate of 80.59% for GSTs1. This study advances the beneficial utilization of (S)-(−)-palasonin as a botanical pesticide to control P. xylostella in the field.
    Keywords Plutella xylostella (L.) ; (S)-(−)-palasonin ; botanical insecticide ; metabolism ; Science ; Q
    Subject code 570
    Language English
    Publishing date 2022-10-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Effects of Simulated Acid Rain on Soil Enzyme Activity and Related Chemical Indexes in Woodlands

    Yifan Zheng / Yunqi Wang / Yonglin Zheng / Yifan Li

    Forests, Vol 13, Iss 860, p

    2022  Volume 860

    Abstract: In order to explore the effects of different concentrations of acid rain on soil nutrient content and nutrient utilization efficiency, and to provide a basis for an improvement in acidified soil in acid rain regions, a year-long acid rain experiment was ... ...

    Abstract In order to explore the effects of different concentrations of acid rain on soil nutrient content and nutrient utilization efficiency, and to provide a basis for an improvement in acidified soil in acid rain regions, a year-long acid rain experiment was conducted in a typical evergreen broad-leaved forest and coniferous and broad-leaved mixed forest in Jinyun Mountain of Chongqing. Four pH treatments (pH 4.5, 4.0, 3.25, and 2.5) were established to simulate acid rain. The results showed that: (1) Acid rain promoted the accumulation of soil nutrients, and the contents of organic carbon (SOC), total nitrogen (TN), and hydrolyzed nitrogen (HN) significantly increased during the experiment ( p < 0.05). (2) Soil SOC content was significantly positively correlated with acid rain concentration ( p < 0.01), HN content was negatively correlated with acid rain concentration, and TN and total phosphorus (TP) contents were not significantly correlated with acid rain concentration. (3) The activities of soil sucrase, urease, and acid phosphatase were negatively correlated with acid rain concentration ( p < 0.01) and the activity of soil cellulase was positively correlated with acid rain concentration ( p < 0.01). (4) The enzyme activity changed differently, depending on the concentration of acid rain during the study period. (5) According to RDA analysis, soil total nitrogen content and hydrolyzed nitrogen content had significant effects on enzyme activity ( p < 0.05). Conclusions: Acid rain did not significantly alter the overall soil nutrient content but reduced the available nutrient content and seriously inhibited enzyme activity—most notably, the soil enzymes involved in nutrient utilization efficiency.
    Keywords acid rain ; acidified soil ; enzyme activity ; Plant ecology ; QK900-989
    Language English
    Publishing date 2022-05-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: Optimal sequence-based design for multi-antigen HIV-1 vaccines using minimally distant antigens

    Eric Lewitus / Jennifer Hoang / Yifan Li / Hongjun Bai / Morgane Rolland

    PLoS Computational Biology, Vol 18, Iss

    2022  Volume 10

    Abstract: The immense global diversity of HIV-1 is a significant obstacle to developing a safe and effective vaccine. We recently showed that infections established with multiple founder variants are associated with the development of neutralization breadth years ... ...

    Abstract The immense global diversity of HIV-1 is a significant obstacle to developing a safe and effective vaccine. We recently showed that infections established with multiple founder variants are associated with the development of neutralization breadth years later. We propose a novel vaccine design strategy that integrates the variability observed in acute HIV-1 infections with multiple founder variants. We developed a probabilistic model to simulate this variability, yielding a set of sequences that present the minimal diversity seen in an infection with multiple founders. We applied this model to a subtype C consensus sequence for the Envelope (Env) (used as input) and showed that the simulated Env sequences mimic the mutational landscape of an infection with multiple founder variants, including diversity at antibody epitopes. The derived set of multi-founder-variant-like, minimally distant antigens is designed to be used as a vaccine cocktail specific to a HIV-1 subtype or circulating recombinant form and is expected to promote the development of broadly neutralizing antibodies. Author summary Diverse HIV-1 populations are generally thought to promote neutralizing responses. Current leading HIV-1 vaccine design strategies maximize the distance between antigens to attempt to cover global HIV-1 diversity or serialize immunizations to recapitulate the temporal evolution of HIV-1 during infection. To date, no vaccine has elicited broadly neutralizing antibodies. As we recently demonstrated that infection with multiple HIV-1 founder variants is predictive of neutralization breadth, we propose a novel strategy that endeavors to promote the development of broadly neutralizing antibodies by replicating the diversity of multi-founder variant acute infections. By training an HIV-1 Env consensus sequence on the diversity from acute infections with multiple founders, we derived in silico a set of minimally distant antigens that is representative of the diversity seen in a multi-founder acute infection. As the model is ...
    Keywords Biology (General) ; QH301-705.5
    Subject code 005
    Language English
    Publishing date 2022-10-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: Efficacy of a new day surgery management mode based on WeChat

    Yun Shi / Xiaoqian Deng / Junyu Yan / Shuangwen Wang / Yifan Li

    BMJ Open, Vol 12, Iss

    a study protocol for randomised controlled trials

    2022  Volume 8

    Abstract: Introduction There is an enormous imbalance between the rapid development of day surgery and the current conventional medical services. Hence, an effective day surgery management mode should be developed that can be used to constantly follow up on ... ...

    Abstract Introduction There is an enormous imbalance between the rapid development of day surgery and the current conventional medical services. Hence, an effective day surgery management mode should be developed that can be used to constantly follow up on patients both preoperatively and postoperatively. In this study, WeChat was chosen as the platform. This study aimed to investigate the feasibility and effectiveness of a new day surgery management mode.Methods and analysis This randomised controlled study investigated the efficacy of a new day surgery management mode based on WeChat. The target number of participants was 1000 per group. The application (app) will send personalised information based on the medical history of the patient and the type of surgery at different time points preoperatively and postoperatively. The healthcare worker can follow up the patient and acquire clinical data by simply signing into the app. The patient and the healthcare worker can also engage in video or voice chats using the app when necessary. Multiple departments, including anaesthesiology, internal medicine, surgery, nursing and psychology, will participate in this new mode.Ethics and dissemination Ethical approval was obtained from the West China Hospital of Sichuan University Biomedical Research Ethics Committee. Results of this study will be published in peer-reviewed journals and presented at international conferences.Trial registration number ChiCTR2100050793.
    Keywords Medicine ; R
    Language English
    Publishing date 2022-08-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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