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Buch ; Online: Differentially Private Online Bayesian Estimation With Adaptive Truncation

Yıldırım, Sinan

2023

Abstract: We propose a novel online and adaptive truncation method for differentially private Bayesian online estimation of a static parameter regarding a population. We assume that sensitive information from individuals is collected sequentially and the ... ...

Abstract	We propose a novel online and adaptive truncation method for differentially private Bayesian online estimation of a static parameter regarding a population. We assume that sensitive information from individuals is collected sequentially and the inferential aim is to estimate, on-the-fly, a static parameter regarding the population to which those individuals belong. We propose sequential Monte Carlo to perform online Bayesian estimation. When individuals provide sensitive information in response to a query, it is necessary to perturb it with privacy-preserving noise to ensure the privacy of those individuals. The amount of perturbation is proportional to the sensitivity of the query, which is determined usually by the range of the queried information. The truncation technique we propose adapts to the previously collected observations to adjust the query range for the next individual. The idea is that, based on previous observations, we can carefully arrange the interval into which the next individual's information is to be truncated before being perturbed with privacy-preserving noise. In this way, we aim to design predictive queries with small sensitivity, hence small privacy-preserving noise, enabling more accurate estimation while maintaining the same level of privacy. To decide on the location and the width of the interval, we use an exploration-exploitation approach a la Thompson sampling with an objective function based on the Fisher information of the generated observation. We show the merits of our methodology with numerical examples. Comment: 17 pages, 3 figures, Code available
Schlagwörter	Computer Science - Machine Learning ; Statistics - Computation ; Statistics - Machine Learning
Thema/Rubrik (Code)	310
Erscheinungsdatum	2023-01-19
Erscheinungsland	us
Dokumenttyp	Buch ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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Artikel ; Online: Psychometric Support and Measurement Invariance of a Turkish Version of the Transformational Parenting Questionnaire.

Yıldırım, Sinan / Sarıkaya, Serap

Perceptual and motor skills

2024 , Seite(n) 315125241247860

Abstract: Our primary objective in this study was to psychometrically evaluate the Transformational Parenting Questionnaire (TPQ) within the Turkish context. Secondarily, we aimed to determine whether the questionnaire demonstrated measurement invariance across ... ...

Abstract	Our primary objective in this study was to psychometrically evaluate the Transformational Parenting Questionnaire (TPQ) within the Turkish context. Secondarily, we aimed to determine whether the questionnaire demonstrated measurement invariance across children's genders and grade levels. We included 950 participants, aged 11-18 years (446 girls, 498 boys, 6 unspecified gender identity;
Sprache	Englisch
Erscheinungsdatum	2024-04-17
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	204507-2
ISSN	1558-688X ; 0031-5125
ISSN (online)	1558-688X
ISSN	0031-5125
DOI	10.1177/00315125241247860
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel: Comparison of bleeding risk scores and evaluation of major bleeding predictive factors in patients with major bleeding due to vitamin K antagonist use.

Yildirim, Sinan / Aslan, Onur

Heliyon

2023 Band 9, Heft 8, Seite(n) e19079

Abstract: Background: Major bleeding in the treatment of atrial fibrillation is closely associated with an increased risk of death and major adverse outcomes in both the short and long term, but all bleeding events are associated with a reduced quality of life. ... ...

Abstract	Background: Major bleeding in the treatment of atrial fibrillation is closely associated with an increased risk of death and major adverse outcomes in both the short and long term, but all bleeding events are associated with a reduced quality of life. Bleeding events are also known to reduce medication adherence. In this sense, bleeding risk scores are important tools to help predict major bleeding. However, it is not clear which scoring system is superior. Aim: In this study, our aim was to compare bleeding risk scores and to examine the factors associated with bleeding in patients with major bleeding while using vitamin K antagonists. Methods: In this retrospective and single-center study, scoring, laboratory and demographic data were analyzed with SPSS 20.0 statistical program. Results: The mean age of a total of 1434 patients included in our study was 68.2 ± 11.3 years, range was 39-93 years and 769 (53.6%) of these patients were male. Of 588 patients with major bleeding, 93 (15.8%) had intracranial hemorrhage. Logistic regression analysis comparing the scoring systems among themselves revealed that the GARFIELD-AF scoring system had a predictive effect on major bleeding independent of the effect of other scoring systems (OR: 1.532, 95% CI 1.348-1.741, p < 0.001). The area under the curve (AUC) for GARFIELD-AF was 0.690 (0.662-0.718) as a result of the ROC analysis considering the best cut-off point of 3.2% calculated for 2 years. AUC 0.659 (0.630-0.687) for HAS-BLED, AUC 0.636 (0.606-0.665) for ORBIT and AUC 0.611 (0.5810.642) for ATRIA. When we compare the patient group with the control group, it can be said that intracranial hemorrhage occurred independently of INR and TTR values, unlike in the major bleeding group (p:0.129, p:0.545). Conclusion: In patients using vitamin K antagonists for atrial fibrillation, the GARFIELD-AF risk score was found to be superior to important bleeding risk scores such as HAS-BLED, ORBIT and ATRIA in terms of predicting major bleeding. It is an important result that intracranial hemorrhages, which have a special place among major hemorrhages, were independent of INR and TTR levels. It is noteworthy that 8.2% of patients with major bleeding had a history of minor bleeding in the last year.
Sprache	Englisch
Erscheinungsdatum	2023-08-12
Erscheinungsland	England
Dokumenttyp	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e19079
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Psychometric Properties and Measurement Invariance of the Positive Youth Development Scale - Turkish Version.

Yıldırım, Sinan / Arslan, Yunus

Perceptual and motor skills

2023 Band 130, Heft 6, Seite(n) 2362–2387

Abstract: In this study, we translated to Turkish and evaluated the validity, reliability, and measurement invariance for respondent sex, grade level and analysis programs the Short Form and Very Short Form of the Positive Youth Development Scale (Turkish version). ...

Abstract	In this study, we translated to Turkish and evaluated the validity, reliability, and measurement invariance for respondent sex, grade level and analysis programs the Short Form and Very Short Form of the Positive Youth Development Scale (Turkish version). We had 435 youth, aged 11-17 years, complete the Short (34 items) and Very Short (17 items) Forms of the instrument. Confirmatory factor analysis revealed that both forms had a 5-factor structure, and validity testing showed good criterion-related correlation validity between this tool and the Satisfaction with Life Scale. The Short Form had adequate reliability coefficients, but the Very Short Form lacked sufficient reliability for some dimensions. Test-retest correlations were satisfactory for both forms. While the Short and Very Short Forms showed measurement invariance across gender and grade level, CFI, NNFI (TLI), and IFI values diverged between LISREL and AMOS analysis programs. In summary, our data suggest that the Short Form is a reliable measure of positive youth development, while the Very Short Form may not be as reliable due to insufficient confidence values.
Mesh-Begriff(e)	Humans ; Adolescent ; Surveys and Questionnaires ; Psychometrics ; Reproducibility of Results ; Factor Analysis, Statistical
Sprache	Englisch
Erscheinungsdatum	2023-10-17
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	204507-2
ISSN	1558-688X ; 0031-5125
ISSN (online)	1558-688X
ISSN	0031-5125
DOI	10.1177/00315125231206311
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: The effects of cardiopulmonary resuscitation (CPR) performed out-of-hospital and in-hospital with manual or automatic device methods and laboratory parameters on survival of patients with cardiac arrest.

Yıldırım, Sinan / Varışlı, Behcet

Irish journal of medical science

2023 Band 192, Heft 5, Seite(n) 2365–2371

Abstract: Objective: Determining the predictive factors for cardiac arrest may be helpful in the management of in-hospital cardiac arrest (IHCA) and out-of-hospital cardiac arrest (OHCA) and in estimating the outcome. Therefore, in the present study, we aimed to ... ...

Abstract	Objective: Determining the predictive factors for cardiac arrest may be helpful in the management of in-hospital cardiac arrest (IHCA) and out-of-hospital cardiac arrest (OHCA) and in estimating the outcome. Therefore, in the present study, we aimed to investigate the effect of demographic data, cardiopulmonary resuscitation (CPR) initiating setting, compression method, and laboratory parameters on survival from cardiac arrest. Methods: A total of 414 patients who met the inclusion criteria were included in the study. Patients were grouped into those who underwent out-of-hospital CPR and those who underwent CPR in the hospital and patients who received automatic compression and those who did not receive. In addition to pH, lactate and bicarbonate in arterial blood gas, CK-MB, troponin, urea, creatinine, calcium, potassium, and glucose were measured. Results: The mean age of patients was 70.36±15.68 years, and 170 (41.1%) were female. Although the success rate of CPR in the OHCA group (22.2%) was lower than in the patients in the IHCA group (30.9%), the difference was not statistically significant. There was no difference between the two groups in the comparison of mechanical compression devices and manual compression. In the logistic regression analysis, high pH and low lactate values were found to be independent predictors of survival. Conclusion: The results of this study revealed no significant difference between IHCA and OHCA CPR applications and between manual and mechanical compressions in terms of survival in patients with cardiac arrest. In addition, higher pH levels and lower lactate levels measured during CPR were independent predictors of survival.
Mesh-Begriff(e)	Humans ; Female ; Middle Aged ; Aged ; Aged, 80 and over ; Male ; Cardiopulmonary Resuscitation/methods ; Out-of-Hospital Cardiac Arrest/therapy ; Hospitals ; Lactates
Chemische Substanzen	Lactates
Sprache	Englisch
Erscheinungsdatum	2023-06-02
Erscheinungsland	Ireland
Dokumenttyp	Journal Article
ZDB-ID	390895-1
ISSN	1863-4362 ; 0021-1265
ISSN (online)	1863-4362
ISSN	0021-1265
DOI	10.1007/s11845-023-03406-6
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Rivaroxaban and apixaban in patients with atrial fibrillation; a real-world data.

Aslan, Onur / Yıldırım, Sinan

Turkish journal of medical sciences

2022 Band 52, Heft 4, Seite(n) 948–957

Abstract: Background: This study aims to analyze the real-life data of patients who were prescribed rivaroxaban and apixaban and to emphasize the points that we think will make a difference compared to randomized controlled studies.: Methods: The patients who ... ...

Abstract	Background: This study aims to analyze the real-life data of patients who were prescribed rivaroxaban and apixaban and to emphasize the points that we think will make a difference compared to randomized controlled studies. Methods: The patients who accepted to participate in the study in whom rivaroxaban (15-20 mg) and apixaban (2.5-5 mg) were started with the diagnosis of atrial fibrillation between 01 January 2018 and 31 December 2019 and whose records were fully accessed through the hospital automation system were included in the study. Results: One hundred and ninety-four (48.5%) of a total of 400 patients using rivaroxaban and apixaban were women. The mean age was 73.34 ± 10.45 years, and the age range was 41-98. There was no significant difference in terms of demographic characteristics, background information of the patients, and the medications. Drug-induced complications and mortality rates were also similar. The GFR change rates of the patients in both groups were similar even though the initial GFRs were significantly higher in rivaroxaban group. The mean age and ejection fractions of the patients using rivaroxaban 15 mg were found to be lower than those of patients using rivaroxaban 20 mg whereas the mean systolic blood pressure and HAS-BLED score were found to be higher. Ischemic stroke and mortality rates were higher in patients using 15 mg rivaroxaban than patients using 20 mg rivaroxaban. The rates of nonmajor bleeding in patients using rivaroxaban 15 mg were lower compared to those using 20 mg, and this difference was statistically significant. Discussion: Stroke rates were found to be higher and to have similar bleeding rates compared to major clinical studies in our real-life analysis. However, high ischemic cerebrovascular event and low nonmajor bleeding rates are remarkable in low dose use of rivaroxaban. It is clear that there is a need to consider existing dose reduction criteria in terms of correct prescribing.
Mesh-Begriff(e)	Humans ; Female ; Middle Aged ; Aged ; Aged, 80 and over ; Male ; Rivaroxaban/therapeutic use ; Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Anticoagulants/adverse effects ; Pyridones/adverse effects ; Hemorrhage/chemically induced ; Hemorrhage/epidemiology ; Stroke/epidemiology ; Stroke/prevention & control ; Stroke/complications ; Administration, Oral ; Retrospective Studies
Chemische Substanzen	Rivaroxaban (9NDF7JZ4M3) ; apixaban (3Z9Y7UWC1J) ; Anticoagulants ; Pyridones
Sprache	Englisch
Erscheinungsdatum	2022-08-10
Erscheinungsland	Turkey
Dokumenttyp	Journal Article
ZDB-ID	1183461-4
ISSN	1303-6165 ; 1300-0144
ISSN (online)	1303-6165
ISSN	1300-0144
DOI	10.55730/1300-0144.5395
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Artikel ; Online: Translation and Adaptation of the Reinjury Anxiety Inventory, the Sport Injury Rehabilitation Adherence Scale, and the Athletic Injury Self-Efficacy Questionnaire Into Turkish.

Turkeri-Bozkurt, Hande / Yıldırım, Sinan / Brewer, Britton W / Bayrakcı Tunay, Volga / Koruç, Ziya

Journal of sport rehabilitation

2024 Band 33, Heft 4, Seite(n) 231–236

Abstract: Context: Psychological difficulties can adversely affect rehabilitation outcomes and make return to sport more difficult. Identifying psychological difficulties is possible with valid and reliable measurement tools. The purpose of this study is to ... ...

Abstract	Context: Psychological difficulties can adversely affect rehabilitation outcomes and make return to sport more difficult. Identifying psychological difficulties is possible with valid and reliable measurement tools. The purpose of this study is to translate and culturally adapt the Reinjury Anxiety Inventory (RIAI), the Sport Injury Rehabilitation Adherence Scale (SIRAS), and the Athletic Injury Self-Efficacy Questionnaire (AISEQ) into Turkish and evaluate the psychometric properties of the Turkish versions. Design: Cross-sectional study. Methods: The instruments were forward- and back-translated, culturally adapted, and validated on 248 athletes and 34 physical therapists. The physical therapists of the athletes completed the SIRAS to evaluate the athletes. Statistical analysis included reliability tests (Cronbach alpha and test-retest), exploratory factor analysis, confirmatory factor analysis, and correlational analysis. Floor and ceiling effects (<15%) were also assessed. Results: Confirmatory factor analyses revealed a satisfactory model fit for the RIAI and the AISEQ, and exploratory factor analysis revealed the 1-factor structure for the SIRAS as in the original. All 3 instruments displayed adequate internal consistency (Cronbach alpha coefficients ranged from .84 to .88) and test-retest reliability (coefficients ranged from .81 to .93). Convergent validity of the instruments was supported by significant correlations between the AISEQ and both the RIAI and the SIRAS. Conclusions: Our results suggest that the Turkish versions of the instruments were valid, consistent, and reliable in athletes who have serious injuries. Scores on these instruments could be useful for evaluating the contributions of psychological factors to return to sport following serious injuries. Clinicians are encouraged to use RIAI-Turkish (RIAI-TR), SIRAS-Turkish (SIRAS-TR), and AISEQ-Turkish (AISEQ-TR) together to make decisions about the treatment and rehabilitation plans of injured athletes.
Mesh-Begriff(e)	Humans ; Athletic Injuries/rehabilitation ; Athletic Injuries/psychology ; Turkey ; Male ; Female ; Cross-Sectional Studies ; Psychometrics ; Self Efficacy ; Surveys and Questionnaires/standards ; Adult ; Reproducibility of Results ; Anxiety ; Young Adult ; Adolescent ; Factor Analysis, Statistical ; Return to Sport ; Translations ; Athletes/psychology
Sprache	Englisch
Erscheinungsdatum	2024-02-29
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	1106769-x
ISSN	1543-3072 ; 1056-6716
ISSN (online)	1543-3072
ISSN	1056-6716
DOI	10.1123/jsr.2023-0273
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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Buch ; Online: Statistic Selection and MCMC for Differentially Private Bayesian Estimation

Alparslan, Baris / Yildirim, Sinan

2022

Abstract: This paper concerns differentially private Bayesian estimation of the parameters of a population distribution, when a statistic of a sample from that population is shared in noise to provide differential privacy. This work mainly addresses two problems: ( ...

Abstract	This paper concerns differentially private Bayesian estimation of the parameters of a population distribution, when a statistic of a sample from that population is shared in noise to provide differential privacy. This work mainly addresses two problems: (1) What statistic of the sample should be shared privately? For the first question, i.e., the one about statistic selection, we promote using the Fisher information. We find out that, the statistic that is most informative in a non-privacy setting may not be the optimal choice under the privacy restrictions. We provide several examples to support that point. We consider several types of data sharing settings and propose several Monte Carlo-based numerical estimation methods for calculating the Fisher information for those settings. The second question concerns inference: (2) Based on the shared statistics, how could we perform effective Bayesian inference? We propose several Markov chain Monte Carlo (MCMC) algorithms for sampling from the posterior distribution of the parameter given the noisy statistic. The proposed MCMC algorithms can be preferred over one another depending on the problem. For example, when the shared statistics is additive and added Gaussian noise, a simple Metropolis-Hasting algorithm that utilizes the central limit theorem is a decent choice. We propose more advanced MCMC algorithms for several other cases of practical relevance. Our numerical examples involve comparing several candidate statistics to be shared privately. For each statistic, we perform Bayesian estimation based on the posterior distribution conditional on the privatized version of that statistic. We demonstrate that, the relative performance of a statistic, in terms of the mean squared error of the Bayesian estimator based on the corresponding privatized statistic, is adequately predicted by the Fisher information of the privatized statistic. Comment: References to the algorithms are corrected. (Only change w.r.t. v1)
Schlagwörter	Statistics - Methodology ; Computer Science - Machine Learning ; Statistics - Computation ; Statistics - Machine Learning
Thema/Rubrik (Code)	310
Erscheinungsdatum	2022-03-24
Erscheinungsland	us
Dokumenttyp	Buch ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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Buch ; Online: Differentially Private Distributed Bayesian Linear Regression with MCMC

Alparslan, Barış / Yıldırım, Sinan / Birbil, Ş. İlker

2023

Abstract: We propose a novel Bayesian inference framework for distributed differentially private linear regression. We consider a distributed setting where multiple parties hold parts of the data and share certain summary statistics of their portions in privacy- ... ...

Abstract	We propose a novel Bayesian inference framework for distributed differentially private linear regression. We consider a distributed setting where multiple parties hold parts of the data and share certain summary statistics of their portions in privacy-preserving noise. We develop a novel generative statistical model for privately shared statistics, which exploits a useful distributional relation between the summary statistics of linear regression. Bayesian estimation of the regression coefficients is conducted mainly using Markov chain Monte Carlo algorithms, while we also provide a fast version to perform Bayesian estimation in one iteration. The proposed methods have computational advantages over their competitors. We provide numerical results on both real and simulated data, which demonstrate that the proposed algorithms provide well-rounded estimation and prediction. Comment: 15 pages, 4 figures, code available at: https://github.com/sinanyildirim/Bayesian_DP_dist_LR
Schlagwörter	Statistics - Machine Learning ; Computer Science - Machine Learning ; Statistics - Computation
Thema/Rubrik (Code)	310
Erscheinungsdatum	2023-01-31
Erscheinungsland	us
Dokumenttyp	Buch ; Online
Datenquelle	BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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Artikel ; Online: Relationship Between Prognostic Nutritional Index and Contrast-Associated Acute Kidney Injury in Patients With Non-ST Segment Elevation Myocardial Infarction Undergoing Coronary Angiography.

Hatem, Engin / Aslan, Onur / Demirci, Emre E / Yildirim, Sinan

Angiology

2022 Band 74, Heft 7, Seite(n) 672–679

Abstract: Prognostic nutritional index (PNI), consisting of inflammatory-nutritional parameters, has been investigated in terms of outcomes and renal function in patients with coronary artery disease. The objective of this study is to assess the predictive power ... ...

Abstract	Prognostic nutritional index (PNI), consisting of inflammatory-nutritional parameters, has been investigated in terms of outcomes and renal function in patients with coronary artery disease. The objective of this study is to assess the predictive power of the PNI in predicting the risk for developing contrast-associated acute kidney injury (CA-AKI), an important complication following coronary angiography in patients with non-ST-elevation myocardial infarction (NSTEMI). The study population (336 patients with the diagnosis of NSTEMI) was divided into two groups: patients with CA-AKI and patients without CA-AKI. The mean age of the whole population was 62.0 ± 12.7 (21-95) years. CA-AKI was detected in 68 (20%) patients. Prognostic nutritional index values were significantly (
Mesh-Begriff(e)	Humans ; Middle Aged ; Aged ; Coronary Angiography/adverse effects ; Non-ST Elevated Myocardial Infarction/diagnostic imaging ; Non-ST Elevated Myocardial Infarction/complications ; Nutrition Assessment ; Contrast Media/adverse effects ; Prognosis ; Risk Factors ; Percutaneous Coronary Intervention/adverse effects ; Acute Kidney Injury/chemically induced ; Acute Kidney Injury/diagnosis
Chemische Substanzen	Contrast Media
Sprache	Englisch
Erscheinungsdatum	2022-08-17
Erscheinungsland	United States
Dokumenttyp	Journal Article
ZDB-ID	80040-5
ISSN	1940-1574 ; 0003-3197
ISSN (online)	1940-1574
ISSN	0003-3197
DOI	10.1177/00033197221113158
Datenquelle	MEDical Literature Analysis and Retrieval System OnLINE

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