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  1. Article: Towards Environment-Aware Fall Risk Assessment: Classifying Walking Surface Conditions Using IMU-Based Gait Data and Deep Learning.

    Yıldız, Abdulnasır

    Brain sciences

    2023  Volume 13, Issue 10

    Abstract: Fall risk assessment (FRA) helps clinicians make decisions about the best preventative measures to lower the risk of falls by identifying the different risks that are specific to an individual. With the development of wearable technologies such as ... ...

    Abstract Fall risk assessment (FRA) helps clinicians make decisions about the best preventative measures to lower the risk of falls by identifying the different risks that are specific to an individual. With the development of wearable technologies such as inertial measurement units (IMUs), several free-living FRA methods based on fall predictors derived from IMU-based data have been introduced. The performance of such methods could be improved by increasing awareness of the individuals' walking environment. This study aims to introduce and analyze a 25-layer convolutional neural network model for classifying nine walking surface conditions using IMU-based gait data, providing a basis for environment-aware FRAs. A database containing data collected from thirty participants who wore six IMU sensors while walking on nine surface conditions was employed. A systematic analysis was conducted to determine the effects of gait signals (acceleration, magnetic field, and rate of turn), sensor placement, and signal segment size on the method's performance. Accuracies of 0.935 and 0.969 were achieved using a single and dual sensor, respectively, reaching an accuracy of 0.971 in the best-case scenario with optimal settings. The findings and analysis can help to develop more reliable and interpretable fall predictors, eventually leading to environment-aware FRA methods.
    Language English
    Publishing date 2023-10-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2651993-8
    ISSN 2076-3425
    ISSN 2076-3425
    DOI 10.3390/brainsci13101428
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  2. Article ; Online: Laparoscopic transabdominal preperitoneal and totally extraperitoneal in inguinal hernia surgery: comparison of intraoperative and postoperative early complications of two techniques.

    Yildiz, Abdullah

    Journal of minimally invasive surgery

    2022  Volume 25, Issue 1, Page(s) 18–23

    Abstract: Purpose: Totally extraperitoneal (TEP) and transabdominal preperitoneal (TAPP) are laparoscopic techniques frequently used in inguinal hernia surgeries. There are very few studies directly comparing the outcomes of TEP and TAPP. The present study ... ...

    Abstract Purpose: Totally extraperitoneal (TEP) and transabdominal preperitoneal (TAPP) are laparoscopic techniques frequently used in inguinal hernia surgeries. There are very few studies directly comparing the outcomes of TEP and TAPP. The present study compared both techniques' technical aspects, intraoperative and postoperative early complications.
    Methods: In this study, 108 patients diagnosed with inguinal hernia underwent laparoscopic surgery between May 2016 and December 2020. Seventy six of these patients (70.4%) underwent TEP, and 32 (29.6%) underwent TAPP. This study was retrospective. However, the data were registered prospectively (including video recordings).
    Results: No significant difference was found between the groups regarding age, sex, body mass index, American Society of Anesthesiologist physical status classification, and duration of hospitalization. Although the TEP group had a higher overall complication rate than TAPP, the difference between the two groups was not significant (TEP, 9.2% vs. TAPP, 3.1%,
    Conclusion: In our study, conversion and intraoperative early postoperative complications were more prevalent in TEP than TAPP. On the other hand, no significant difference was determined between the results of the two techniques. It has been found that TAPP is as safe as TEP in inguinal hernia surgery; however, the superiority of one method over the other was not observed in this study.
    Language English
    Publishing date 2022-05-16
    Publishing country Korea (South)
    Document type Journal Article
    ISSN 2234-5248
    ISSN (online) 2234-5248
    DOI 10.7602/jmis.2022.25.1.18
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Lichtenstein and Total Extraperitoneal Techniques in Inguinal Hernia Surgery: A Comparison of the Intraoperative and Early Postoperative Complications Between the Two Approaches.

    Yıldız, Abdullah

    Cureus

    2022  Volume 14, Issue 8, Page(s) e28020

    Abstract: Background and objective The Lichtenstein technique (LSt) and total extraperitoneal technique (TEPt) are the most frequently performed surgical procedures for inguinal hernia (IH). This study aimed to compare LSt and TEPt in terms of intraoperative and ... ...

    Abstract Background and objective The Lichtenstein technique (LSt) and total extraperitoneal technique (TEPt) are the most frequently performed surgical procedures for inguinal hernia (IH). This study aimed to compare LSt and TEPt in terms of intraoperative and postoperative complications as well as recurrence rates. Methods This retrospective study involved patients hospitalized for IH repair. The study included a total of 262 patients (LSt group: n=125; TEPt group: n=137).  Results The follow-up period of the patients ranged between 16 and 30 months (mean: 22.3 months). While intraoperative complications were more commonly reported in the TEPt group, postoperative complications were more common in the LSt group (2.9% vs. 1.6%). Postoperative bleeding/hematoma developed in three (2.4%) patients in the LSt and three (2.2%) in the TEPt group. One of the patients in the LSt group was reoperated due to persistent bleeding. Two patients in the LSt and two in the TEPt group were reoperated for postoperative recurrence (1.6% vs. 2.4%). One patient was reoperated due to chronic persistent pain. Seroma was aspirated in three (2.4%) patients in the LSt and two (1.5%) in the TEPt group. Conclusion This study revealed no significant difference between TEPt and LSt groups regarding intraoperative and postoperative complications. We propose that both TEPt and LSt could be safely performed in cases of primary and complex IH by selecting the appropriate method based on the hernia type and patient and with sufficient surgical experience.
    Language English
    Publishing date 2022-08-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.28020
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  4. Article ; Online: Dynamic folding and accessibility of telomeric overhang.

    Yildiz, Ahmet

    Proceedings of the National Academy of Sciences of the United States of America

    2022  Volume 119, Issue 38, Page(s) e2211219119

    MeSH term(s) Fluorescence Resonance Energy Transfer ; G-Quadruplexes ; Humans ; Single Molecule Imaging ; Telomere/chemistry ; Telomere Homeostasis ; Telomere-Binding Proteins/chemistry
    Chemical Substances Telomere-Binding Proteins
    Language English
    Publishing date 2022-09-07
    Publishing country United States
    Document type Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.2211219119
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  5. Article ; Online: UV photodetectors based on W-doped ZnO thin films.

    Jalal, R / Ozel, K / Atilgan, A / Yildiz, A

    Nanotechnology

    2024  Volume 35, Issue 26

    Abstract: W-doped ZnO thin films deposited on Si substrates with (100) orientation by sol-gel spin coating method at temperature 500 °C. W/Zn atomic ratio varies from 0% to 4%. Then, the UV detection performance analysis ... ...

    Abstract W-doped ZnO thin films deposited on Si substrates with (100) orientation by sol-gel spin coating method at temperature 500 °C. W/Zn atomic ratio varies from 0% to 4%. Then, the UV detection performance analysis of
    Language English
    Publishing date 2024-04-09
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362365-5
    ISSN 1361-6528 ; 0957-4484
    ISSN (online) 1361-6528
    ISSN 0957-4484
    DOI 10.1088/1361-6528/ad373b
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  6. Article ; Online: Partial primary closure in sacrococcygeal pilonidal sinus: Modified with suture technique.

    Yildiz, Abdullah

    Asian journal of surgery

    2021  Volume 45, Issue 1, Page(s) 381–385

    Abstract: Aim and background: The primary purpose of pilonidal sinus treatment is to minimize complications, accelerate wound healing, and minimize recurrence. However, invasive and minimally invasive methods are being developed to reduce these problems. Early ... ...

    Abstract Aim and background: The primary purpose of pilonidal sinus treatment is to minimize complications, accelerate wound healing, and minimize recurrence. However, invasive and minimally invasive methods are being developed to reduce these problems. Early and late postoperative complications remain significant problems in pilonidal surgery. This study aimed to contribute to this issue in surgery by comparing the results of the Karydakis flap (KF) technique and those of the partial primary closure (PPC) technique, to which we applied suture modification.
    Methods: A total of 96 patients diagnosed with pilonidal sinus disease (PSD) were randomly assigned to two groups. Apply the partial primary closure in 46 patients and the Karydakis technique in 50.
    Results: In comparison to the Karydakis technique, the partial primary closure (PPC) group's hospitalization stay was shorter, although the difference was not significant. Healing time was also longer in uncomplicated cases (p = 0.200 and 0.064, respectively). Abscesses and hematomas were not observed with partial primary closure, but the total complication rate was similar to that of the Karydakis technique. Surgical site infections were often seen in the PPC group (21.7% vs. 10%). In contrast, healing time for complicated cases was found to be significantly shorter in the PPC technique (p < 0.05).
    Conclusion: Postoperative abscess, hematoma, and seroma are the most common causes of total wound dehiscence, and delay in wound healing in off-midline techniques. We recommend the PPC technique with suture modification as an alternative to off-midline techniques in clean and chronically infected cases, other than cellulitis, abscess, and purulent discharge cases. However, we primarily recommend off-midline techniques in clean or asymptomatic cases.
    MeSH term(s) Humans ; Neoplasm Recurrence, Local ; Pilonidal Sinus/surgery ; Recurrence ; Sacrococcygeal Region ; Surgical Flaps ; Suture Techniques
    Language English
    Publishing date 2021-07-21
    Publishing country China
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 1068461-x
    ISSN 0219-3108 ; 1015-9584
    ISSN (online) 0219-3108
    ISSN 1015-9584
    DOI 10.1016/j.asjsur.2021.06.029
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  7. Article ; Online: The Role of Speedy/RINGO Protein in Breast Cancer as a Future Biomarker.

    Tanriverdi, Ozgur / Yildiz, Aysegul

    Cancer diagnosis & prognosis

    2024  Volume 4, Issue 3, Page(s) 209–213

    Abstract: Background/aim: Cyclin-dependent kinases (CDKs) are proteins that require the binding of regulatory subunits called cyclins and play a key role in cell cycle progression and activation. CDKs play a key role in carcinogenesis of many solid malignancies, ... ...

    Abstract Background/aim: Cyclin-dependent kinases (CDKs) are proteins that require the binding of regulatory subunits called cyclins and play a key role in cell cycle progression and activation. CDKs play a key role in carcinogenesis of many solid malignancies, and inhibition of these proteins has produced anti-cancer effects demonstrated in preclinical studies. This narrative review was conducted to develop a hypothetical approach to determine whether Speedy/RINGO, a protein associated with CDK2, could be a possible predictive factor in breast cancer patients treated with a CDK4/6 inhibitor.
    Materials and methods: A literature search was conducted in PubMed, Web of Science, Medline, and Google Scholars search engines to match the following words: "Speedy/RINGO" or "Spy1" and "CDKs" or "Cyclin-dependent kinases (CDKs)" and "CDK4/6 inhibitors" and "Regulation" and "Molecular" and "Breast cancer" and "Carcinogenesis". Only articles investigating the relationship between the Speedy/RINGO protein and CDKs at the molecular level were included. Literature information was compiled by trying to establish a relationship with our hypothesis question.
    Results: Speedy/RINGO is a tightly regulated proto-oncogenic mammalian protein playing important roles in the somatic cell cycle. Studies have emphasized that although it does not have amino acid sequence homology with cyclins, it can activate CDK2. In addition, results showing molecular compensation of CDK4/6 inhibition through CDK2 activation, also showed that CDK2 can predict drug resistance. Another important finding was that overexpressed Speedy/RINGO, during CDK4/6 inhibitor treatment, could strongly activate CDK2, resulting in a negative response to treatment.
    Conclusion: Although many predictive factors have been investigated to indicate response to CDK4/6 inhibitors or determine drug resistance, a consensus biomarker has yet to be established. In light of the information obtained from our review, it can be concluded that the Speedy/RINGO protein may have an important role as a predictive biomarker in terms of response to treatment, continuity of treatment and drug resistance in patients treated with CDK4/6 inhibitors.
    Language English
    Publishing date 2024-05-03
    Publishing country Greece
    Document type Journal Article ; Review
    ISSN 2732-7787
    ISSN (online) 2732-7787
    DOI 10.21873/cdp.10310
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  8. Article: The effect of utilitarian motivations in online consumption behavior

    Yildiz, A.

    Journal of Critical Reviews

    Abstract: Online shopping has been a method in which consumers shop intensively, especially in the Covid-19 process There are two main motivation motives in shaping the shopping behavior of consumers The first is hedonic motivations and the other is utilitarian ... ...

    Abstract Online shopping has been a method in which consumers shop intensively, especially in the Covid-19 process There are two main motivation motives in shaping the shopping behavior of consumers The first is hedonic motivations and the other is utilitarian motives In this study, it was investigated whether motivational impulses that direct consumers to online shopping vary according to their effect levels and demographic variables For this purpose in Turkey online (online) was obtained as a poll carried out and 448 valid As a result of the analyzes, it was observed that consumers participated in the proposals that they offer the most product variety and different payment opportunities In age, profession and economic status assessment options;It was determined that there was no statistically significant difference between the averages of the utilitarian motivation dimensions According to gender;convenience, adaptability and payment services;in terms of the level of education, the availability of information and payment services;In terms of monthly income level, there was a statistically significant difference in desire for control, lack of social interaction and privacy dimensions © 2020 by Advance Scientific Research
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #833249
    Database COVID19

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  9. Article: Incarcerated Appendix Epiploica in Inguinal Hernia Sac: Treatment with Laparoscopic TAPP Approach-Report of a Rare Case.

    Yildiz, Abdullah

    Case reports in surgery

    2020  Volume 2020, Page(s) 4178523

    Abstract: Appendix epiploica (AE) in an incarcerated inguinal hernia sac is very rare. We herein report the case of a 57-year-old man admitted to the emergency department with complaints of nausea, swelling, and pain in the left inguinal area. He was diagnosed ... ...

    Abstract Appendix epiploica (AE) in an incarcerated inguinal hernia sac is very rare. We herein report the case of a 57-year-old man admitted to the emergency department with complaints of nausea, swelling, and pain in the left inguinal area. He was diagnosed with left incarcerated inguinal hernia and treated laparoscopically with transabdominal preperitoneal (TAPP) mesh hernioplasty. During the operation, AE, lodged in the direct hernia sac, was seen to originate from the sigmoid colon. The narrow internal inguinal ring was incised at the 2 o'clock position using a monopolar hook, and the hypertrophic AE was reduced to the abdomen and resected. The patient was discharged uneventfully on the second postoperative day.
    Language English
    Publishing date 2020-02-21
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2657697-1
    ISSN 2090-6919 ; 2090-6900
    ISSN (online) 2090-6919
    ISSN 2090-6900
    DOI 10.1155/2020/4178523
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  10. Article: The comparison of the intraocular lens power calculation formulas in long eyes.

    Yildiz, Aydin

    JPMA. The Journal of the Pakistan Medical Association

    2020  Volume 70, Issue 7, Page(s) 1173–1176

    Abstract: Objective: To investigate the accurate intraocular lens power formula in eyes with axial length over 26mm by using optical biometry.: Methods: The retrospective case series was conducted at Medicana International Avcilar Hospital, Istanbul, Turkey ... ...

    Abstract Objective: To investigate the accurate intraocular lens power formula in eyes with axial length over 26mm by using optical biometry.
    Methods: The retrospective case series was conducted at Medicana International Avcilar Hospital, Istanbul, Turkey from 2016 to 2018, and comprised data related to years between 2014 and 2018. Optical low-coherence reflectometry had been used in measurements. The calculation methods were included Hill-radial basis function, Sanders-Retzlaff-Kraff-Theoretical, Hoffer Q, Barrett Universal II, Olsen, Haigis and Holladay-2. The spherical equivalent values that were obtained with automated refractometer at the first postoperative month were recorded. Mean absolute error for each formula was estimated. SPSS 16 was used for data analysis.
    Results: There were 56 eyes of as many patients with a mean axial length of 26.70±0.88mm. The postoperative numerical error was within ±0.50 diopters in 46(82%) patients, and between the -0.50 and -1.00 diopters in 10(18%). The mean absolute error values were significantly lower in Haigis, Sanders-Retzlaff-Kraff-Theoretical, HofferQ and Holladay-2 formulas compared to the Barrett, Hill, and Olsen formulas (p<0.05). There was no statistically significant intra-group difference for Haigis, Sanders-Retzlaff-Kraff-Theoretical, Hoffer Q, and Holladay-2 formulas (p>0.05).
    Conclusions: In long eyes with an axial length over 26mm, Haigis, Sanders-Retzlaff-Kraff-Theoretical, Hoffer Q and Holladay-2 formulas yielded better postoperative refractive outcomes compared to Hill-radial basis function, Barrett Universal IIand Olsen formulas. The Haigis formula had the lowest refractive numerical error.
    MeSH term(s) Axial Length, Eye ; Biometry ; Humans ; Lens Implantation, Intraocular ; Lenses, Intraocular ; Optics and Photonics ; Refraction, Ocular ; Retrospective Studies ; Turkey ; Visual Acuity
    Language English
    Publishing date 2020-08-06
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 603873-6
    ISSN 0030-9982
    ISSN 0030-9982
    DOI 10.5455/JPMA.15406
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