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Article: [Advances in exosomes derived from the mesenchymal stem cells in the treatment of sepsis].

Wang, S / Yin, H Y

Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns

2019 Volume 35, Issue 1, Page(s) 77–80

Abstract: Exosomes derived from mesenchymal stem cells (MSCs) are small membrane vesicles with diameters in 30-150 nm, which are secreted into extracellular matrix by MSCs in resting or activated state. Recent studies have found that exosomes secreted by MSCs can ... ...

Abstract	Exosomes derived from mesenchymal stem cells (MSCs) are small membrane vesicles with diameters in 30-150 nm, which are secreted into extracellular matrix by MSCs in resting or activated state. Recent studies have found that exosomes secreted by MSCs can be used as important signal transduction mediator, which can transport bioactive substances such as mRNA, microRNA, and proteins effectively to target cells, and play important roles in regulating tissue regeneration and immunomodulation. Here we give an overview of biological properties, mechanisms, and the roles in treating sepsis of exosome derived from MSCs, in order to provide some basises to highlight the MSCs-exosomes therapy in sepsis.
MeSH term(s)	Exosomes ; Humans ; Immunomodulation ; Mesenchymal Stem Cells ; MicroRNAs ; Sepsis/therapy
Chemical Substances	MicroRNAs
Language	Chinese
Publishing date	2019-01-22
Publishing country	China
Document type	Journal Article ; Review
ZDB-ID	2229222-6
ISSN	1009-2587
ISSN	1009-2587
DOI	10.3760/cma.j.issn.1009-2587.2019.01.016
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Article: [Advances in the research of sepsis-related stress response].

Qiu, M S / Yin, H Y

Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns

2016 Volume 32, Issue 12, Page(s) 765–768

Abstract: In recent years, the levels of anti-infection and organ function support of sepsis have been improved, but the mortality rate remains high, which brings about challenges for critical care clinicians. Sources of sepsis-related stress response include ... ...

Abstract	In recent years, the levels of anti-infection and organ function support of sepsis have been improved, but the mortality rate remains high, which brings about challenges for critical care clinicians. Sources of sepsis-related stress response include severe infection, frequent therapeutic procedures, routine nursing measures, and physical constraints, etc. Although sepsis-related stress response has obtained a lot of concern, its understanding is still in the stage of research and the treatment method is nonspecific. This article summarizes the pathogenesis, evaluation methods, and treatment of sepsis-related stress response, with a hope to provide reference for its clinical treatment.
MeSH term(s)	Anti-Bacterial Agents/therapeutic use ; Anti-Infective Agents/therapeutic use ; Critical Care/trends ; Disease Management ; Humans ; Sepsis/physiopathology ; Sepsis/therapy ; Shock, Septic/physiopathology ; Stress, Physiological/physiology
Chemical Substances	Anti-Bacterial Agents ; Anti-Infective Agents
Language	Chinese
Publishing date	2016-12-20
Publishing country	China
Document type	Journal Article
ZDB-ID	2229222-6
ISSN	1009-2587
ISSN	1009-2587
DOI	10.3760/cma.j.issn.1009-2587.2016.12.014
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Article ; Online: Clinical analysis of relapsing polychondritis with airway involvement.

Zhai, S-Y / Guo, R-Y / Zhang, C / Zhang, C-M / Yin, H-Y / Wang, B-Q / Wen, S-X

The Journal of laryngology and otology

2022 , Page(s) 1–5

Abstract: Objective: To identify the clinical characteristics, treatment, and prognosis of relapsing polychondritis patients with airway involvement.: Methods: Twenty-eight patients with relapsing polychondritis, hospitalised in the First Hospital of Shanxi ... ...

Abstract	Objective: To identify the clinical characteristics, treatment, and prognosis of relapsing polychondritis patients with airway involvement. Methods: Twenty-eight patients with relapsing polychondritis, hospitalised in the First Hospital of Shanxi Medical University between April 2011 and April 2021, were retrospectively analysed. Results: Fifty per cent of relapsing polychondritis patients with airway involvement had a lower risk of ear and ocular involvement. Relapsing polychondritis patients with airway involvement had a longer time-to-diagnosis ( Conclusion: For relapsing polychondritis patients with airway involvement, drug treatment should be combined with local airway management.
Language	English
Publishing date	2022-02-02
Publishing country	England
Document type	Journal Article
ZDB-ID	218299-3
ISSN	1748-5460 ; 0022-2151
ISSN (online)	1748-5460
ISSN	0022-2151
DOI	10.1017/S002221512200038X
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Article: [Advances in the research of protective effect of curcumin on intestinal mucosal barrier function].

He, D / Wang, S / Hu, H / Yin, H Y

Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns

2019 Volume 35, Issue 2, Page(s) 157–160

Abstract: As a natural extract from turmeric, curcumin has extensive pharmacological effects, such as anti-tumor, anti-inflammation, anti-oxidative stress, anti-microbial, immunoregulation and so on. In recent years, an increasing number of basic and clinical ... ...

Abstract	As a natural extract from turmeric, curcumin has extensive pharmacological effects, such as anti-tumor, anti-inflammation, anti-oxidative stress, anti-microbial, immunoregulation and so on. In recent years, an increasing number of basic and clinical researches have shown that curcumin takes therapeutic effects on various diseases, such as gastrointestinal diseases, cardiovascular diseases, autoimmune diseases, neuropsychiatric diseases and so on. Many of the pharmacological effects and mechanisms of curcumin are associated with protective effects of intestinal mucosal barrier. It can protect intestinal mucosal barrier through mutiple pathways, including anti-inflammation, anti-oxidative stress, anti-bacterial, anti-apoptosis, regulating intestinal microecology and intestinal immune response and so on. This paper summarizes the protective effects of curcumin on intestinal barrier function and the mechanism, in order to provide new ideas for diagnosis and treatment of intestinal dysfunction.
MeSH term(s)	Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Curcumin/pharmacology ; Curcumin/therapeutic use ; Humans ; Inflammation/drug therapy ; Inflammation/metabolism ; Intestinal Mucosa/metabolism ; Intestines/drug effects ; Oxidative Stress/drug effects
Chemical Substances	Anti-Inflammatory Agents ; Curcumin (IT942ZTH98)
Language	Chinese
Publishing date	2019-02-18
Publishing country	China
Document type	Journal Article ; Review
ZDB-ID	2229222-6
ISSN	1009-2587
ISSN	1009-2587
DOI	10.3760/cma.j.issn.1009-2587.2019.02.013
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Article ; Online: Combined multiplex loop-mediated isothermal amplification with lateral flow assay to detect sea and seb genes of enterotoxic Staphylococcus aureus.

Yin, H Y / Fang, T J / Wen, H W

Letters in applied microbiology

2016 Volume 63, Issue 1, Page(s) 16–24

Abstract: Unlabelled: Staphylococcal enterotoxins (SEs) are the most common cause of food poisoning worldwide and can induce symptoms, such as diarrhoea, vomiting and abdominal cramping. Thus, the aim of this study is to develop a multiplex loop-mediated ... ...

Abstract	Unlabelled: Staphylococcal enterotoxins (SEs) are the most common cause of food poisoning worldwide and can induce symptoms, such as diarrhoea, vomiting and abdominal cramping. Thus, the aim of this study is to develop a multiplex loop-mediated isothermal amplification combined with a lateral flow assay (m-LAMP/LFA) to simultaneously detect the sea and seb genes of Staphylococcus aureus. The amplicons of the sea gene were labelled with digoxigenin (Dig) and biotin while those of seb gene were labelled with fluorescein isothiocyanate (FITC) and biotin. These amplicons were detected using a multiplex LFA with NeutrAvidin-tagged gold nanoparticles as the detection reagent. After optimization, the detection limit of this assay was 10(2) CFU ml(-1) Staph. aureus, which was one tenth that of a multiplex PCR. This assay did not exhibit any cross-reactivity in detecting other enterotoxic Staph. aureus strains or other food pathogens. After 6 h of enrichment, this developed assay detected 1 CFU ml(-1) of Staph. aureus in milk, apple juice, cheese and rice. The developed m-LAMP/LFA method does not require expensive equipment and can be completely implemented within an 8-h workday. Therefore, this method can provide an effective means of quickly screening staphylococcal enterotoxin A- and/or staphylococcal enterotoxin B-producing Staph. aureus in food samples. Significance and impact of the study: Staphylococcus aureus is one of the major foodborne pathogens worldwide, and its staphylococcal enterotoxin A and B are strongly associated with food poisoning. This work developed a multiplex loop-mediated isothermal amplification combined with a lateral flow assay (m-LAMP/LFA) to simultaneously detect the sea and seb genes of Staph. aureus in food samples. The assay has good specificity and sensitivity with ease-of-use features, making it ideal for on-site detection.
MeSH term(s)	Animals ; Cheese/microbiology ; Enterotoxins/genetics ; Food Microbiology ; Fruit and Vegetable Juices/microbiology ; Limit of Detection ; Milk/microbiology ; Multiplex Polymerase Chain Reaction/methods ; Nucleic Acid Amplification Techniques/methods ; Oryza/microbiology ; Sensitivity and Specificity ; Staphylococcus aureus/genetics ; Staphylococcus aureus/pathogenicity
Chemical Substances	Enterotoxins ; enterotoxin A, Staphylococcal (37337-57-8) ; enterotoxin B, staphylococcal (39424-53-8)
Language	English
Publishing date	2016-07
Publishing country	England
Document type	Journal Article
ZDB-ID	632584-1
ISSN	1472-765X ; 0266-8254
ISSN (online)	1472-765X
ISSN	0266-8254
DOI	10.1111/lam.12590
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Article: [Analysis of electrocardiogram and blood related indicators in workers occupationally exposed to mercury in Jiangsu Province from 2016 to 2018].

Yu, P / Yin, H Y / Guo, J D / Ding, E M / Zhu, B L / Chen, S J

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases

2020 Volume 37, Issue 12, Page(s) 949–952

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	China ; Creatinine/blood ; Electrocardiography ; Humans ; Mercury/adverse effects ; Mercury/urine ; Occupational Exposure/adverse effects ; Occupational Exposure/statistics & numerical data
Chemical Substances	Creatinine (AYI8EX34EU) ; Mercury (FXS1BY2PGL)
Language	Chinese
Publishing date	2020-01-08
Publishing country	China
Document type	Journal Article
ISSN	1001-9391
ISSN	1001-9391
DOI	10.3760/cma.j.issn.1001-9391.2019.12.020
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Article: Combined multiplex loopâmediated isothermal amplification with lateral flow assay to detect sea and seb genes of enterotoxic Staphylococcus aureus

Yin, H.Y / T.J. Fang / H.W. Wen

Letters in applied microbiology. 2016 July, v. 63, no. 1

2016

Abstract: Staphylococcal enterotoxins (SEs) are the most common cause of food poisoning worldwide and can induce symptoms, such as diarrhoea, vomiting and abdominal cramping. Thus, the aim of this study is to develop a multiplex loopâmediated isothermal ... ...

Abstract	Staphylococcal enterotoxins (SEs) are the most common cause of food poisoning worldwide and can induce symptoms, such as diarrhoea, vomiting and abdominal cramping. Thus, the aim of this study is to develop a multiplex loopâmediated isothermal amplification combined with a lateral flow assay (mâLAMP/LFA) to simultaneously detect the sea and seb genes of Staphylococcus aureus. The amplicons of the sea gene were labelled with digoxigenin (Dig) and biotin while those of seb gene were labelled with fluorescein isothiocyanate (FITC) and biotin. These amplicons were detected using a multiplex LFA with NeutrAvidinâtagged gold nanoparticles as the detection reagent. After optimization, the detection limit of this assay was 10Â²Â CFUÂ mlâ»Â¹ Staph.Â aureus, which was one tenth that of a multiplex PCR. This assay did not exhibit any crossâreactivity in detecting other enterotoxic Staph.Â aureus strains or other food pathogens. After 6Â h of enrichment, this developed assay detected 1Â CFUÂ mlâ»Â¹ of Staph.Â aureus in milk, apple juice, cheese and rice. The developed mâLAMP/LFA method does not require expensive equipment and can be completely implemented within an 8âh workday. Therefore, this method can provide an effective means of quickly screening staphylococcal enterotoxin Aâ and/or staphylococcal enterotoxin Bâproducing Staph.Â aureus in food samples. SIGNIFICANCE AND IMPACT OF THE STUDY: Staphylococcus aureus is one of the major foodborne pathogens worldwide, and its staphylococcal enterotoxin A and B are strongly associated with food poisoning. This work developed a multiplex loopâmediated isothermal amplification combined with a lateral flow assay (mâLAMP/LFA) to simultaneously detect the sea and seb genes of Staph.Â aureus in food samples. The assay has good specificity and sensitivity with easeâofâuse features, making it ideal for onâsite detection.
Keywords	Staphylococcus aureus ; apple juice ; bacterial contamination ; biotin ; cheeses ; cross reaction ; detection limit ; digoxigenin ; enterotoxins ; equipment ; fluorescein ; food contamination ; food pathogens ; foodborne illness ; genes ; loop-mediated isothermal amplification ; milk ; nanogold ; poisoning ; polymerase chain reaction ; rice ; screening
Language	English
Dates of publication	2016-07
Size	p. 16-24.
Publishing place	John Wiley & Sons, Ltd
Document type	Article
Note	JOURNAL ARTICLE
ZDB-ID	632584-1
ISSN	1472-765X ; 0266-8254
ISSN (online)	1472-765X
ISSN	0266-8254
DOI	10.1111/lam.12590
Database	NAL-Catalogue (AGRICOLA)

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Article: [The clinical effect and imaging features of accordion maneuver in promoting bone healing at the docking site after tibial transport under ultrasonic monitoring].

He, G Y / Zhou, X / Shi, Y / Wang, D / Yu, J / Qiao, H Y / Xing, H / Yin, H Y / Zhang, J / Liu, H / Wang, B N / Jia, Y W / Zhang, Y H

Zhonghua wai ke za zhi [Chinese journal of surgery

2021 Volume 59, Issue 6, Page(s) 477–483

Abstract: Objective: ...

Abstract	Objective:
MeSH term(s)	Female ; Fracture Healing ; Humans ; Male ; Radiography ; Retrospective Studies ; Tibia/diagnostic imaging ; Tibial Fractures ; Treatment Outcome ; Ultrasonics ; Wound Healing
Language	Chinese
Publishing date	2021-06-03
Publishing country	China
Document type	Journal Article
ZDB-ID	604573-x
ISSN	0529-5815
ISSN	0529-5815
DOI	10.3760/cma.j.cn112139-20210125-00052
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Article ; Online: Neutrophil Gelatinase-Associated Lipocalin in Cats with Naturally Occurring Chronic Kidney Disease.

Wang, I-C / Hsu, W-L / Wu, P-H / Yin, H-Y / Tsai, H-J / Lee, Y-J

Journal of veterinary internal medicine

2017 Volume 31, Issue 1, Page(s) 102–108

Abstract: Background: Neutrophil gelatinase-associated lipocalin (NGAL) is a biomarker for the early prediction of renal damage and the progression of chronic kidney disease (CKD) in humans and dogs.: Hypothesis: Neutrophil gelatinase-associated lipocalin also ...

Abstract	Background: Neutrophil gelatinase-associated lipocalin (NGAL) is a biomarker for the early prediction of renal damage and the progression of chronic kidney disease (CKD) in humans and dogs. Hypothesis: Neutrophil gelatinase-associated lipocalin also may play a role in the progression of CKD in cats. Animals: Eighty CKD and 18 control cats. Methods: Cats were categorized into different stages according to the International Renal Interest Society (IRIS) staging system. Urine and plasma samples were collected and tested for NGAL concentrations using an in-house sandwich ELISA system and urinary NGAL (uNGAL)-to-creatinine ratio (UNCR) was determined. Cats in which serum creatinine concentration increased by >0.5 mg/dL from baseline within 30 days were defined as exhibiting progression. Results: The urinary NGAL and UNCR of CKD cats were significantly higher than those of healthy cats (P < .05) and were highly correlated with serum creatinine concentration. The area under the receiver operating characteristic curve (AUROC) for uNGAL, when predicting the progression of CKD, was 0.71 and the best cutoff value was 2.06 ng/mL with a sensitivity of 76.9% and a specificity of 75%. The AUROC for UNCR when predicting the progression of CKD was 0.79 and the best cutoff value was 4.08 × 10 Conclusions: Both urinary NGAL and UNCR are useful markers for the prediction of CKD progression in cats.
MeSH term(s)	Animals ; Biomarkers/blood ; Blood Chemical Analysis/veterinary ; Case-Control Studies ; Cat Diseases/blood ; Cat Diseases/diagnosis ; Cats ; Female ; Lipocalin-2/blood ; Male ; Renal Insufficiency, Chronic/blood ; Renal Insufficiency, Chronic/diagnosis ; Renal Insufficiency, Chronic/veterinary ; Sensitivity and Specificity
Chemical Substances	Biomarkers ; Lipocalin-2
Language	English
Publishing date	2017-01
Publishing country	United States
Document type	Evaluation Studies ; Journal Article
ZDB-ID	92798-3
ISSN	1939-1676 ; 0891-6640
ISSN (online)	1939-1676
ISSN	0891-6640
DOI	10.1111/jvim.14628
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Book ; Online: A simple and feasible process for using multi-stage high-precision DTMs, field surveys and rainfall data to study debris flow occurrence factors of Shenmu area, Taiwan

Lo, W.-C. / Lin, B.-S. / Ho, H.-C. / Keck, J. / Yin, H.-Y. / Shan, H.-Y.

eISSN: 1684-9981

2018

Abstract: The occurrence of typhoon Herb in 1996 caused massive landslides in the Shenmu area of Taiwan. Many people died and stream and river beds were covered by meters of debris. Debris flows almost always take place in the Shenmu area during the flood season, ... ...

Abstract	The occurrence of typhoon Herb in 1996 caused massive landslides in the Shenmu area of Taiwan. Many people died and stream and river beds were covered by meters of debris. Debris flows almost always take place in the Shenmu area during the flood season, especially in the catchment areas around Tsushui river and Aiyuzih river. Anthropogenic and natural factors that cause debris flow occurrences are complex and numerous. The precise conditions of initiation are difficult to be identified, but three factors are generally considered to be the most important ones, i.e. rainfall characteristics, geologic conditions and topography. This study proposes a simple and feasible process that combines remote sensing technology and multi-stage high-precision DTMs from aerial orthoimages and airborne LiDAR with field surveys to establish a connection between three major occurrence factors that trigger debris flows in the Shenmu area.
Subject code	910
Language	English
Publishing date	2018-09-27
Publishing country	de
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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