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  1. Article: Case - Management of bullet retained in penile shaft after drive-by shooting.

    Levitt, Max / Ying, Thomas / Elzayat, Ehab Abdalla

    Canadian Urological Association journal = Journal de l'Association des urologues du Canada

    2021  Volume 16, Issue 3, Page(s) E181–E183

    Language English
    Publishing date 2021-10-21
    Publishing country Canada
    Document type Journal Article
    ZDB-ID 2431403-1
    ISSN 1911-6470
    ISSN 1911-6470
    DOI 10.5489/cuaj.7480
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A Newborn with Retrovesical Cysts and an Ipsilateral Multicystic Dysplastic Kidney.

    Ying, Thomas / Degheili, Jad A / Guerra, Luis

    Urology

    2021  Volume 157, Page(s) 42–43

    Abstract: We present a clinical imaging question focusing on a newborn with known prenatal history of a multicystic dysplastic kidney, and incidental ipsilateral retrovesical seminal vesical cysts, raising the diagnosis of Zinner syndrome. The diagnosis is ... ...

    Abstract We present a clinical imaging question focusing on a newborn with known prenatal history of a multicystic dysplastic kidney, and incidental ipsilateral retrovesical seminal vesical cysts, raising the diagnosis of Zinner syndrome. The diagnosis is challenging in this age group. Surgical management is generally proposed for symptomatic cases at an older age.
    MeSH term(s) Cysts/complications ; Cysts/diagnostic imaging ; Genital Diseases, Male/complications ; Genital Diseases, Male/diagnostic imaging ; Humans ; Infant, Newborn ; Male ; Multicystic Dysplastic Kidney/complications ; Multicystic Dysplastic Kidney/diagnostic imaging ; Seminal Vesicles ; Syndrome ; Urinary Bladder
    Language English
    Publishing date 2021-04-02
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 192062-5
    ISSN 1527-9995 ; 0090-4295
    ISSN (online) 1527-9995
    ISSN 0090-4295
    DOI 10.1016/j.urology.2021.03.023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1142: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 275: Show issues

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  3. Article ; Online: Salmonella Thompson splenic abscess in a healthy female.

    Bonares, Michael J / Ying, Thomas / Patel, Yashesh

    BMJ case reports

    2017  Volume 2017

    Abstract: A 26-year-old woman presented with a 5-day history of fever and 3-day history of left upper quadrant abdominal pain and cough associated with left shoulder tip pain. Initial blood cultures did not display growth. On CT imaging, there was a cyst measuring ...

    Abstract A 26-year-old woman presented with a 5-day history of fever and 3-day history of left upper quadrant abdominal pain and cough associated with left shoulder tip pain. Initial blood cultures did not display growth. On CT imaging, there was a cyst measuring 7.2×8 cm originally interpreted to be haemorrhagic in nature. Repeat cultures during admission revealed Salmonella Thompson. Percutaneous drainage and antibiotic treatment, rather than splenectomy, was successfully pursued with the patient afebrile and in no pain at 6 weeks follow-up.
    MeSH term(s) Abscess/complications ; Abscess/diagnosis ; Abscess/diagnostic imaging ; Abscess/surgery ; Adult ; Anti-Bacterial Agents/administration & dosage ; Anti-Bacterial Agents/therapeutic use ; Diagnosis, Differential ; Drainage ; Female ; Fever/etiology ; Humans ; Infusions, Intravenous ; Salmonella/isolation & purification ; Salmonella Infections/complications ; Salmonella Infections/diagnosis ; Salmonella Infections/diagnostic imaging ; Salmonella Infections/surgery ; Shoulder Pain/etiology ; Splenic Diseases/complications ; Splenic Diseases/diagnosis ; Splenic Diseases/diagnostic imaging ; Splenic Diseases/surgery
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2017-08-23
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2016-218595
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Automated artificial intelligence-based analysis of skeletal muscle volume predicts overall survival after cystectomy for urinary bladder cancer.

    Ying, Thomas / Borrelli, Pablo / Edenbrandt, Lars / Enqvist, Olof / Kaboteh, Reza / Trägårdh, Elin / Ulén, Johannes / Kjölhede, Henrik

    European radiology experimental

    2021  Volume 5, Issue 1, Page(s) 50

    Abstract: Background: Radical cystectomy for urinary bladder cancer is a procedure associated with a high risk of complications, and poor overall survival (OS) due to both patient and tumour factors. Sarcopenia is one such patient factor. We have developed a ... ...

    Abstract Background: Radical cystectomy for urinary bladder cancer is a procedure associated with a high risk of complications, and poor overall survival (OS) due to both patient and tumour factors. Sarcopenia is one such patient factor. We have developed a fully automated artificial intelligence (AI)-based image analysis tool for segmenting skeletal muscle of the torso and calculating the muscle volume.
    Methods: All patients who have undergone radical cystectomy for urinary bladder cancer 2011-2019 at Sahlgrenska University Hospital, and who had a pre-operative computed tomography of the abdomen within 90 days of surgery were included in the study. All patients CT studies were analysed with the automated AI-based image analysis tool. Clinical data for the patients were retrieved from the Swedish National Register for Urinary Bladder Cancer. Muscle volumes dichotomised by the median for each sex were analysed with Cox regression for OS and logistic regression for 90-day high-grade complications. The study was approved by the Swedish Ethical Review Authority (2020-03985).
    Results: Out of 445 patients who underwent surgery, 299 (67%) had CT studies available for analysis. The automated AI-based tool failed to segment the muscle volume in seven (2%) patients. Cox regression analysis showed an independent significant association with OS (HR 1.62; 95% CI 1.07-2.44; p = 0.022). Logistic regression did not show any association with high-grade complications.
    Conclusion: The fully automated AI-based CT image analysis provides a low-cost and meaningful clinical measure that is an independent biomarker for OS following radical cystectomy.
    MeSH term(s) Artificial Intelligence ; Cystectomy/adverse effects ; Female ; Humans ; Male ; Muscle, Skeletal/diagnostic imaging ; Retrospective Studies ; Urinary Bladder Neoplasms/diagnostic imaging ; Urinary Bladder Neoplasms/surgery
    Language English
    Publishing date 2021-11-19
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 2509-9280
    ISSN (online) 2509-9280
    DOI 10.1186/s41747-021-00248-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Prevalence and predictors of complementary and alternative medicine modalities in patients with chronic hepatitis B.

    Liem, Kin Seng / Yim, Colina / Ying, Thomas D / Zanjir, Wayel R / Fung, Scott / Wong, David K / Shah, Hemant / Feld, Jordan J / Hansen, Bettina E / Janssen, Harry L A

    Liver international : official journal of the International Association for the Study of the Liver

    2019  Volume 39, Issue 8, Page(s) 1418–1427

    Abstract: Background & aims: The use of complementary and alternative medicine (CAM) in patients with chronic hepatitis B (CHB) can interact with antiviral treatment or influence health-seeking behaviour. We aimed to study the use of individual CAM modalities in ... ...

    Abstract Background & aims: The use of complementary and alternative medicine (CAM) in patients with chronic hepatitis B (CHB) can interact with antiviral treatment or influence health-seeking behaviour. We aimed to study the use of individual CAM modalities in CHB and explore determinants of use, particularly migration-related, socio-economic and clinical factors.
    Methods: A total of 436 CHB outpatients who attended the Toronto Centre for Liver Disease in 2015-2016 were included in this cross-sectional study. Using the comprehensive I-CAM questionnaire and health records, data were collected on socio-demographic and clinical variables and on usage of 16 CAM modalities in the last year.
    Results: Sixty percent of patients were male, 74% were Asian and 46% were using antiviral treatment. Three-hundred and nine (71%) patients used CAM. Vitamin/mineral preparations (45% of patients) were most commonly used. Overall CAM use and the specific use of potentially injurious CAM, such as green tea extract (9.2%) and St. John's wort (0.2%), were not associated with liver disease severity. Female sex, family history of CHB, lower serum HBV DNA, and higher socio-economic status were independently associated with bio-holistic CAM use, the clinically most-relevant CAM group (P < 0.05); ethnicity, antiviral therapy use and liver disease severity were not.
    Conclusions: CAM use among CHB patients was extensive, especially use of vitamin and mineral preparations, but without direct influence on liver disease severity. Bio-holistic CAM use appeared to be associated with socio-economic status rather than with ethnicity or liver disease severity. Despite the rare use of hepatotoxins, physicians should actively inquire about it.
    MeSH term(s) Adult ; Aged ; Complementary Therapies/psychology ; Complementary Therapies/statistics & numerical data ; Cross-Sectional Studies ; Female ; Hepatitis B, Chronic/therapy ; Humans ; Male ; Middle Aged ; Sociological Factors
    Language English
    Publishing date 2019-04-22
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2102783-3
    ISSN 1478-3231 ; 1478-3223
    ISSN (online) 1478-3231
    ISSN 1478-3223
    DOI 10.1111/liv.14105
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1632: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Glycolytic metabolism is essential for CCR7 oligomerization and dendritic cell migration.

    Guak, Hannah / Al Habyan, Sara / Ma, Eric H / Aldossary, Haya / Al-Masri, Maia / Won, So Yoon / Ying, Thomas / Fixman, Elizabeth D / Jones, Russell G / McCaffrey, Luke M / Krawczyk, Connie M

    Nature communications

    2018  Volume 9, Issue 1, Page(s) 2463

    Abstract: Dendritic cells (DCs) are first responders of the innate immune system that integrate signals from external stimuli to direct context-specific immune responses. Current models suggest that an active switch from mitochondrial metabolism to glycolysis ... ...

    Abstract Dendritic cells (DCs) are first responders of the innate immune system that integrate signals from external stimuli to direct context-specific immune responses. Current models suggest that an active switch from mitochondrial metabolism to glycolysis accompanies DC activation to support the anabolic requirements of DC function. We show that early glycolytic activation is a common program for both strong and weak stimuli, but that weakly activated DCs lack long-term HIF-1α-dependent glycolytic reprogramming and retain mitochondrial oxidative metabolism. Early induction of glycolysis is associated with activation of AKT, TBK, and mTOR, and sustained activation of these pathways is associated with long-term glycolytic reprogramming. We show that inhibition of glycolysis impaired maintenance of elongated cell shape, DC motility, CCR7 oligomerization, and DC migration to draining lymph nodes. Together, our results indicate that early induction of glycolysis occurs independent of pro-inflammatory phenotype, and that glycolysis supports DC migratory ability regardless of mitochondrial bioenergetics.
    MeSH term(s) Animals ; Cell Differentiation ; Cell Movement/immunology ; Cell Shape/physiology ; Dendritic Cells/immunology ; Dendritic Cells/physiology ; Female ; Glycolysis/physiology ; Lymph Nodes/cytology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mitochondria/metabolism ; Oxidative Phosphorylation ; Receptors, CCR7/metabolism
    Chemical Substances Ccr7 protein, mouse ; Receptors, CCR7
    Language English
    Publishing date 2018-06-25
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-018-04804-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Outcomes of severely comminuted (type III) nasoorbitoethmoid fractures.

    Herford, Alan S / Ying, Thomas / Brown, Brandon

    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons

    2005  Volume 63, Issue 9, Page(s) 1266–1277

    Abstract: Purpose: Nasoorbitoethmoid (NOE) fractures are complex and often challenging to repair. Inadequate treatment may result in secondary deformities which are difficult to treat. Severely comminuted fractures require repositioning of the medial canthal ... ...

    Abstract Purpose: Nasoorbitoethmoid (NOE) fractures are complex and often challenging to repair. Inadequate treatment may result in secondary deformities which are difficult to treat. Severely comminuted fractures require repositioning of the medial canthal tendon. The purpose of this study was to evaluate all results in treating these challenging injuries. The work is to be used as a basis for continuing quality improvement of our surgical technique.
    Patients and methods: [corrected] Ten consecutive patients who sustained a comminuted NOE (type III) fracture were included in this study. All patients had comminution of the central fragment involving the detachment of the medial canthus.
    Results: Transnasal reduction, primary grafting, and plate and screw fixation were used for all patients. Two patients demonstrated slight asymmetry between the medial canthi. Two patients were observed to have overprojection in the nasofrontal region.
    Conclusion: Severely comminuted type III NOE fractures are best treated primarily to avoid secondary deformities.
    MeSH term(s) Bone Plates ; Bone Screws ; Bone Transplantation ; Ethmoid Bone/injuries ; Eyelids/injuries ; Eyelids/surgery ; Female ; Follow-Up Studies ; Fracture Fixation, Internal ; Fracture Healing ; Fractures, Comminuted/surgery ; Frontal Bone/injuries ; Humans ; Male ; Maxillary Fractures/surgery ; Nasal Bone/injuries ; Orbital Fractures/surgery ; Quality Assurance, Health Care ; Skull Fractures/surgery ; Treatment Outcome
    Language English
    Publishing date 2005-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392404-x
    ISSN 1531-5053 ; 0278-2391
    ISSN (online) 1531-5053
    ISSN 0278-2391
    DOI 10.1016/j.joms.2005.05.297
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ul III Zs.113: Show issues Location:
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