LIVIVO - Search results -

Search results

Result 1 - 10 of total 13

Search options

Article ; Online: Application of the Reflectionless Discrete Perfectly Matched Layer for Acoustic Wave Simulation

Yingjie Gao / Meng-Hua Zhu

Frontiers in Earth Science, Vol

2022 Volume 10

Abstract: The perfectly matched layer (PML) is one of the most popular absorbing boundary conditions for simulating seismic waves. In theory, the PML can absorb incident waves at any incident angle and any frequency in a medium. However, numerical reflections will ...

Abstract	The perfectly matched layer (PML) is one of the most popular absorbing boundary conditions for simulating seismic waves. In theory, the PML can absorb incident waves at any incident angle and any frequency in a medium. However, numerical reflections will be generated after the PML has been discretized. Therefore, how to reduce the reflections of discrete PML has been a research topic for more than 2 decades. In this paper, we adopt the reflectionless discrete PML (RD-PML) for seismic wave and implement the RD-PML based on the acoustic wave equation, and then compare its absorbing performance with that of the conventional discrete PML. Our numerical experiments show that the RD-PML has advantages over the conventional discrete PML. In homogeneous model, a thick enough RD-PML can effectively eliminate reflections. In heterogeneous model, a thin-layer RD-PML can obtain better absorbing performance even than the thick-layer conventional discrete PML. The absorbing performance of the RD-PML can be improved by using the periodic boundary without increasing the amount of computation and memory. RD-PML provides a new perspective to understand the discretization of PML, and may play an important role in promoting the development of PML technology.
Keywords	absorbing boundary ; perfectly matched layer ; discrete complex analysis ; periodic boundary ; boundary reflection ; Science ; Q
Subject code	535
Language	English
Publishing date	2022-04-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Research on Mechanism Design and Kinematic Characteristics of Self-Propelled Photovoltaic Cleaning Robot

Jing Yang / Xiaolong Zhao / Yingjie Gao / Rui Guo / Jingyi Zhao

Applied Sciences, Vol 13, Iss 6967, p

2023 Volume 6967

Abstract: A hydraulic drive-based self-propelled photovoltaic panel cleaning robot was developed to tackle the challenges of harsh environmental conditions, difficult roads, and incomplete cleaning of dust particles on the photovoltaic panel surface in ... ...

Abstract	A hydraulic drive-based self-propelled photovoltaic panel cleaning robot was developed to tackle the challenges of harsh environmental conditions, difficult roads, and incomplete cleaning of dust particles on the photovoltaic panel surface in photovoltaic power plants. The robot has the characteristics of the crawler wheel drive, rear-wheel-independent turning and three-point-independent suspension design, which makes it adhere to the walking requirements of complex environmental terrains, more flexible in turning and automatically levelling so that the stability of the boom mechanism during walking can be ensured. The kinematics model of the upper arm structure equipped with the end cleaning device was built, and the optimized Circle chaotic map and nonlinear weight factor were introduced to enhance the search ability and convergence speed of the sparrow algorithm. Furthermore, the boom running track was optimized in combination with the seven-order non-uniform B-spline curve. Through optimization, the running time of the boom was reduced by 18.7%, and the cleaning efficiency of photovoltaic panel surface was increased. The effectiveness of self-propelled photovoltaic panel cleaning robot cleaning and the reliability of time-optimal trajectory planning were confirmed through simulation and experiment.
Keywords	photovoltaic cleaning robot ; structural design ; non-uniform B-spline curve ; improved sparrow algorithm ; time optimal ; Technology ; T ; Engineering (General). Civil engineering (General) ; TA1-2040 ; Biology (General) ; QH301-705.5 ; Physics ; QC1-999 ; Chemistry ; QD1-999
Subject code	629
Language	English
Publishing date	2023-06-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Releasing the Time Step Upper Bound of CFL Stability Condition for the Acoustic Wave Simulation With Model-Order Reduction

Yingjie Gao / Meng-Hua Zhu / Huai Zhang

Frontiers in Earth Science, Vol

2022 Volume 10

Abstract: The maximum time step size for the explicit finite-difference scheme complies with the Courant–Friedrichs–Lewy (CFL) stability condition, which essentially restricts the optimization and tuning of the communication-intensive massive seismic wave ... ...

Abstract	The maximum time step size for the explicit finite-difference scheme complies with the Courant–Friedrichs–Lewy (CFL) stability condition, which essentially restricts the optimization and tuning of the communication-intensive massive seismic wave simulation in a parallel manner. This study brings forward the model-order reduction (MOR) method to simulate acoustic wave propagation. It briefly takes advantage of the update matrix’s eigenvalues and the expansion coefficients of the variables for the time in the semi-discrete scheme of the wave equation, reducing the computational complexity and enhancing its computing efficiency. Moreover, we introduced the eigenvalue abandonment and eigenvalue perturbation methods to stabilize the unstable oscillations when the time step size breaks the CFL stability upper bound. We then introduced the time-dispersion transform method to eliminate the time-dispersion error caused by the large time step and secure the high accuracy. Numerical experiments exhibit that the MOR method, in conjunction with eigenvalue abandonment (and the eigenvalue perturbation) and the time-dispersion transform method, can capture highly accurate waveforms even when the time step size exceeds the CFL stability condition. The eigenvalue perturbation method is suitable for strongly heterogenous media and can maintain the numerical accuracy and stability even when the time step size is toward the upper bound of the Nyquist sampling.
Keywords	explicit finite-difference scheme ; CFL stability upper bound ; model-order reduction ; time-dispersion error ; eigenvalue operation ; Science ; Q
Subject code	518
Language	English
Publishing date	2022-03-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Development of Simple and Accurate in Silico Ligand-Based Models for Predicting ABCG2 Inhibition

Shuheng Huang / Yingjie Gao / Xuelian Zhang / Ji Lu / Jun Wei / Hu Mei / Juan Xing / Xianchao Pan

Frontiers in Chemistry, Vol

2022 Volume 10

Abstract: The ATP binding cassette transporter ABCG2 is a physiologically important drug transporter that has a central role in determining the ADMET (absorption, distribution, metabolism, elimination, and toxicity) profile of therapeutics, and contributes to ... ...

Abstract	The ATP binding cassette transporter ABCG2 is a physiologically important drug transporter that has a central role in determining the ADMET (absorption, distribution, metabolism, elimination, and toxicity) profile of therapeutics, and contributes to multidrug resistance. Thus, development of predictive in silico models for the identification of ABCG2 inhibitors is of great interest in the early stage of drug discovery. In this work, by exploiting a large public dataset, a number of ligand-based classification models were developed using partial least squares-discriminant analysis (PLS-DA) with molecular interaction field- and fingerprint-based structural description methods, regarding physicochemical and fragmental properties related to ABCG2 inhibition. An in-house dataset compiled from recently experimental studies was used to rigorously validated the model performance. The key molecular properties and fragments favored to inhibitor binding were discussed in detail, which was further explored by docking simulations. A highly informative chemical property was identified as the principal determinant of ABCG2 inhibition, which was utilized to derive a simple rule that had a strong capability for differentiating inhibitors from non-inhibitors. Furthermore, the incorporation of the rule into the best PLS-DA model significantly improved the classification performance, particularly achieving a high prediction accuracy on the independent in-house set. The integrative model is simple and accurate, which could be applied to the evaluation of drug-transporter interactions in drug development. Also, the dominant molecular features derived from the models may help medicinal chemists in the molecular design of novel inhibitors to circumvent ABCG2-mediated drug resistance.
Keywords	ABCG2 (BCRP) ; in silico ; prediction ; inhibitors ; PLS-DA ; Chemistry ; QD1-999
Subject code	540
Language	English
Publishing date	2022-05-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Efficient removal of organic pollutant by activation of persulfate with magnetic Co3O4/CoFe2O4 composite

Huixuan Zhang / Li-chao Nengzi / Yu Liu / Yingjie Gao / Xiuwen Cheng

Arabian Journal of Chemistry, Vol 13, Iss 5, Pp 5332-

2020 Volume 5344

Abstract: In this study, magnetic spinel Co3O4/CoFe2O4 composite were synthesized by the mechanical mixing of both powdered pristine samples. Then the catalyst was characterized by TEM, SEM, XRD, BET, XPS and VSM measurement. Next, Co3O4/CoFe2O4 composite was ... ...

Abstract	In this study, magnetic spinel Co3O4/CoFe2O4 composite were synthesized by the mechanical mixing of both powdered pristine samples. Then the catalyst was characterized by TEM, SEM, XRD, BET, XPS and VSM measurement. Next, Co3O4/CoFe2O4 composite was applied to degrade rhodamine B (RhB) in water by activating persulfate. Results showed that Co3O4/CoFe2O4 composite exhibited high efficiency for removal of RhB, and 95.59% of it could be degraded in 45 min. Besides, the effects of parameters, such as initial pH, PS dosage, Co3O4/CoFe2O4 composite dosage, initial concentration of RhB and temperture were studied. Also, the effects of coexisting anions on RhB degradation were observed and explained. Furthermore, we conducted the quenching experiment and found that sulfate radical and hydroxyl radicals were the main active radicals in the degradation process. Finally, recycle experiments proved that Co3O4/CoFe2O4 had a good stability for RhB degradation. In short, Co3O4/CoFe2O4 composite is a promising catalyst for wastewater treatment.
Keywords	Co3O4/CoFe2O4 composite ; Persulfate ; Rhodamine B ; Sulfate radicals ; Hydroxyl radicals ; Chemistry ; QD1-999
Subject code	660
Language	English
Publishing date	2020-05-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Dynamic gene expression analysis in a H1N1 influenza virus mouse pneumonia model

Bao, Yanyan / Yingjie Gao / Yujing Shi / Xiaolan Cui

Virus genes. 2017 June, v. 53, no. 3

2017

Abstract: H1N1, a major pathogenic subtype of influenza A virus, causes a respiratory infection in humans and livestock that can range from a mild infection to more severe pneumonia associated with acute respiratory distress syndrome. Understanding the dynamic ... ...

Abstract	H1N1, a major pathogenic subtype of influenza A virus, causes a respiratory infection in humans and livestock that can range from a mild infection to more severe pneumonia associated with acute respiratory distress syndrome. Understanding the dynamic changes in the genome and the related functional changes induced by H1N1 influenza virus infection is essential to elucidating the pathogenesis of this virus and thereby determining strategies to prevent future outbreaks. In this study, we filtered the significantly expressed genes in mouse pneumonia using mRNA microarray analysis. Using STC analysis, seven significant gene clusters were revealed, and using STC-GO analysis, we explored the significant functions of these seven gene clusters. The results revealed GOs related to H1N1 virus-induced inflammatory and immune functions, including innate immune response, inflammatory response, specific immune response, and cellular response to interferon-beta. Furthermore, the dynamic regulation relationships of the key genes in mouse pneumonia were revealed by dynamic gene network analysis, and the most important genes were filtered, including Dhx58, Cxcl10, Cxcl11, Zbp1, Ifit1, Ifih1, Trim25, Mx2, Oas2, Cd274, Irgm1, and Irf7. These results suggested that during mouse pneumonia, changes in the expression of gene clusters and the complex interactions among genes lead to significant changes in function. Dynamic gene expression analysis revealed key genes that performed important functions. These results are a prelude to advancements in mouse H1N1 influenza virus infection biology, as well as the use of mice as a model organism for human H1N1 influenza virus infection studies.
Keywords	Influenza A virus ; acute respiratory distress syndrome ; gene expression ; human diseases ; humans ; immune response ; inflammation ; innate immunity ; interferon-beta ; livestock ; messenger RNA ; mice ; microarray technology ; models ; multigene family ; pathogenesis ; pneumonia ; viruses
Language	English
Dates of publication	2017-06
Size	p. 357-366.
Publishing place	Springer US
Document type	Article
ZDB-ID	639496-6
ISSN	1572-994X ; 0920-8569
ISSN (online)	1572-994X
ISSN	0920-8569
DOI	10.1007/s11262-017-1438-y
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Cologne/Königswinter

Zs.A 2397: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Human Simulated Intelligent Control with Double-Direction Dead-Zone Compensation for Joint Motion Control of a Large-Sized Boom System

Rongsheng Liu / Yingjie Gao / Yulin Yang / Yanlong Liu

Journal of Control Science and Engineering, Vol

2015 Volume 2015

Abstract: Joint motion control of a 52-meter-long five-boom system driven by proportional hydraulic system is developed. It has been considered difficult due to strong nonlinearities and parametric uncertainties, the effect of which increases with the size of ... ...

Abstract	Joint motion control of a 52-meter-long five-boom system driven by proportional hydraulic system is developed. It has been considered difficult due to strong nonlinearities and parametric uncertainties, the effect of which increases with the size of booms. A human simulated intelligent control scheme is developed to improve control performance by modifying control mode and control parameters. In addition, considering the negative effects caused by frequent and redundant reverse actions of the proportional valve, a double-direction compensation scheme is proposed to deal with the dead-zone nonlinearity of proportional valve. Sinusoidal motions are implemented on a real boom system. The results indicate that HSIC controller can improve control accuracy, and dead-zone nonlinearity is effectively compensated by proposed compensation scheme without introducing frequent reverse actions of proportional valve.
Keywords	Engineering (General). Civil engineering (General) ; TA1-2040 ; Electronic computers. Computer science ; QA75.5-76.95
Subject code	629
Language	English
Publishing date	2015-01-01T00:00:00Z
Publisher	Hindawi Publishing Corporation
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Ameliorative Effects of Infantile Feire Kechuan Oral Solution on Mycoplasma Pneumoniae Pneumonia in Infant Mouse and Rat Models

Shanshan Guo / Lei Bao / Tiange Qu / Xin Mao / Yingjie Gao / Yingli Xu / Xiaolan Cui

Evidence-Based Complementary and Alternative Medicine, Vol

2018 Volume 2018

Abstract: Mycoplasma pneumoniae (MP) infection is a major pathogen of community-acquired pneumonia (CAP) in children worldwide. Infantile Feire Kechuan Oral Solution (IFKOS) has been used for the treatment of MP pneumonia clinically in China for many years. The ... ...

Abstract	Mycoplasma pneumoniae (MP) infection is a major pathogen of community-acquired pneumonia (CAP) in children worldwide. Infantile Feire Kechuan Oral Solution (IFKOS) has been used for the treatment of MP pneumonia clinically in China for many years. The present study was designed to investigate the therapeutic effect of IFKOS on MP pneumonia and explore the potential mechanism of the actions. The infant BALB/c mouse and Wistar rat models of MP infection were successfully established to confirm the therapeutic effects of IFKOS, followed by assays for related cytokines and investigations of the IgM response involved. The results showed that IFKOS exhibited an inhibitory effect on pulmonary index (PI) and effectively reduced the degree of lesions in the lungs. The lethal rate of mice was significantly decreased while survival time of mice was dramatically increased by IFKOS treatment in comparison to infection control, respectively. IFKOS treatment (40, 20, and 10ml/kg) significantly decreased the level of MP-IgM in a dose-dependent manner, whereas IFKOS showed no obvious inhibitory effect on the increase of relative expression of MP-DNA. In addition, the elevated IL-2 and TNF-α levels were significantly reduced and the decreased IL-6 level was significantly enhanced by IFKOS treatment. Our study demonstrates that IFKOS has inhibitory effect on MP infection in infant mouse and rat models of MP pneumonia and protective effect from lethal MP challenge in infant murine model. These anti-MP effects might be related to suppression of the IgM response and a reversal the imbalance of Th1/Th2 cytokines induced by MP infection.
Keywords	Other systems of medicine ; RZ201-999
Subject code	570
Language	English
Publishing date	2018-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Antitumor Effect of Zhihuang Fuzheng Soft Capsules on Tumor-Bearing Mice

Yanyan Bao / Xin Pan / Yahong Jin / Yingjie Gao / Xiaolan Cui

Evidence-Based Complementary and Alternative Medicine, Vol

2016 Volume 2016

Abstract: Chinese medicines (CMs) have been shown to have some advantages in preventing and controlling tumors. In this study, we investigated the antitumor effect of ZFSC by establishing a mouse model of HT-1080, A-549, and HCT-8 tumors. The result showed that ... ...

Abstract	Chinese medicines (CMs) have been shown to have some advantages in preventing and controlling tumors. In this study, we investigated the antitumor effect of ZFSC by establishing a mouse model of HT-1080, A-549, and HCT-8 tumors. The result showed that tumor volumes of HT-1080 tumor-bearing nude mice in ZFSC low, medium, and high dose groups were lower significantly compared to the model group, and the high dose ZFSC showed the best antitumor effect. Tumor volumes of A-549 tumor-bearing nude mice in ZFSC low, medium, and high dose groups were lower significantly compared to the model group and showed a good dose-response relationship. There was no significant effect on human colon cancer, although inhibition trends disappeared in the bar chart. In order to verify the immunomodulatory effect of ZFSC, ELISA was used to analyze serums IL-2, TNF-α, and IFN in spleens. The results showed that ZFSC could enhance the immune function of tumor-bearing mice. ZFSC reduced IFN-γ and TNF-α content in the serum of HT-1080 tumor-bearing mice and inhibit PD1 and PDL1 and suggested that the antitumor mechanism of ZFSC on human fibrosarcoma could be attributed to inhibition of the PDL1/PD1 pathway.
Keywords	Other systems of medicine ; RZ201-999
Subject code	630
Language	English
Publishing date	2016-01-01T00:00:00Z
Publisher	Hindawi Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Nitrogen-doping induces tunable magnetism in ReS2

Qin Zhang / Zemian Ren / Nian Wu / Wenjie Wang / Yingjie Gao / Qiqi Zhang / Jing Shi / Lin Zhuang / Xiangnan Sun / Lei Fu

npj 2D Materials and Applications, Vol 2, Iss 1, Pp 1-

2018 Volume 8

Abstract: Magnetism: nitrogen doping of ReS2 results in tunable magnetic ordering A transition from non-magnetic to magnetic ordering can be induced in ReS2 by means of non-metal doping. At team led by Lei Fu at Wuhan University performed a combined experimental ... ...

Abstract	Magnetism: nitrogen doping of ReS2 results in tunable magnetic ordering A transition from non-magnetic to magnetic ordering can be induced in ReS2 by means of non-metal doping. At team led by Lei Fu at Wuhan University performed a combined experimental and computational investigation aimed at shedding light to the interplay between N doping and the onset of magnetic ordering in anisotropic ReS2. N doping was found to preferentially occur at the edge sites rather than within the plane, and a controlled doping concentration gave rise to a ferromagnetic-antiferromagnetic coupling. Notably, increasing the N content to 4.24 % resulted in a large value of saturated magnetization up to 2.1 emu g−1 at 2 K, and while a further increase to 6.64% led to the suppression of saturated magnetization, it resulted in the onset of an exchange bias of 200 Oe.
Keywords	Materials of engineering and construction. Mechanics of materials ; TA401-492 ; Chemistry ; QD1-999
Language	English
Publishing date	2018-08-01T00:00:00Z
Publisher	Nature Publishing Group
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED