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Article: Effect of the storage atmosphere on metabolomics of harvested tomatoes (Solanum lycopersicum L.)

Yokota, Yuma / Makino, Yoshio

Food Science & Nutrition, 7(2):773-778

2019

Abstract: Harvested tomatoes were stored under atmospheres that were normoxic, anoxic, or modified (altered O2 and CO2 concentrations). Each atmosphere was created by storing the tomatoes at 25°C for up to 8 days in different kinds of pouches. During storage, ... ...

Abstract	Harvested tomatoes were stored under atmospheres that were normoxic, anoxic, or modified (altered O2 and CO2 concentrations). Each atmosphere was created by storing the tomatoes at 25°C for up to 8 days in different kinds of pouches. During storage, metabolites of the tomatoes were measured using metabolomics. We obtained score plots of the metabolites on eighth day of storage by principal component analysis. There was a tendency for groups to be divided on the basis of score plot according to the composition of each gas. PC1 and PC2 seemed to correspond to the influence of O2 and CO2 concentrations, respectively, and the total contribution rate of the two axes was 72%, so that we concluded that the metabolites were affected mainly by O2 and CO2 concentrations. The results indicate that metabolomics may be an effective tool to reveal the relationship between metabolic state of harvested fruits and the atmosphere.
Keywords	environmental gas composition ; modified atmosphere packaging ; metabolomics ; postharvest storage ; principal component analysis ; tomato
Language	English
Document type	Article
Database	Repository for Life Sciences

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Article ; Online: Effects of subjective and objective task difficulties for feedback- related brain potentials in social situations: An electroencephalogram study.

Yokota, Yusuke / Naruse, Yasushi

PloS one

2022 Volume 17, Issue 12, Page(s) e0277663

Abstract: In this study, the relationship between two types of feedback task difficulties and feedback-related brain potentials, such as feedback-related negativity (FRN), reward positivity (RewP), and P300, was investigated in social situations where participants ...

Abstract	In this study, the relationship between two types of feedback task difficulties and feedback-related brain potentials, such as feedback-related negativity (FRN), reward positivity (RewP), and P300, was investigated in social situations where participants performed a task simultaneously by a pair. The electroencephalogram activity was measured while participants answered four-choice questions with their partners. Participants were informed about the general accuracy rate of the question (objective task difficulty) before responding to the questionnaire. The feedback outcome was definitely correct when the participants had the knowledge to answer the questions correctly. Therefore, the subjective task difficulty depended on the knowledge of the participant and differed from the objective task difficulty. In the task, the participants selected the choice they deemed correct. Before checking the answers, participants responded to the preceding question's subjective task difficulty. As one of the social factors, the task consisted of two types of conditions: one, in which one's response affected partner's reward, and another, in which it did not. The second social factor was the order of feedback outcomes; in our experiment, these outcomes were presented sequentially to pairs of participants. The effects of subjective and objective task difficulties and social factors on feedback-related brain potentials were comprehensively analyzed. The study showed that subjective task difficulty sensitively modulated the amplitude of gain-related P300, suggesting that it is sensitive to modulation in the allocation of attentional resources to own feedback outcome. The objective task difficulty sensitively modulated the amplitude of RewP after receiving the partner's incorrect feedback outcome. RewP was more sensitive to positive affective valence, such as feelings of superiority over the partner, than to task-dependent rewards received by the participants themselves. In contrast, FRN was more negative in the joint condition than in the individual condition, suggesting sensitivity to social responsibility felt by participants toward their partners.
MeSH term(s)	Humans ; Feedback ; Electroencephalography ; Brain ; Reward ; Emotions
Language	English
Publishing date	2022-12-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0277663
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Clinical application of endoscopic soft palate augmentation in the treatment of velopharyngeal insufficiency.

Isomura, E T / Matsukawa, M / Yokota, Y / Tanaka, N / Sugiyama, C / Nohara, K

International journal of oral and maxillofacial surgery

2023 Volume 52, Issue 8, Page(s) 854–859

Abstract: Velopharyngeal structure augmentation with the injection of autologous fat tissue into the nasal mucosa of the soft palate has been reported previously. However, as the injection points in the velopharyngeal space cannot be observed directly, these ... ...

Abstract	Velopharyngeal structure augmentation with the injection of autologous fat tissue into the nasal mucosa of the soft palate has been reported previously. However, as the injection points in the velopharyngeal space cannot be observed directly, these injections may be difficult to perform accurately. This report describes a new endoscope-assisted approach in which the materials for velopharyngeal structure augmentation are administered while observing the injection points directly, also enabling adjustment of the amount of material injected. A case series of five patients aged 8-16 years who underwent endoscopic soft palate augmentation under general anaesthesia is reported. Autologous fat tissue was injected into the nasal mucosa of the soft palate using a needle-type device of an endoscope, and the effects of the treatment were evaluated. The injections were performed successfully, and the velopharyngeal function was improved. This new technique of endoscopy-assisted augmentation was useful for the treatment of velopharyngeal insufficiency.
MeSH term(s)	Humans ; Cleft Palate/diagnostic imaging ; Cleft Palate/surgery ; Palate, Soft/abnormalities ; Palate, Soft/transplantation ; Endoscopy ; Velopharyngeal Insufficiency/surgery ; Adipose Tissue/transplantation ; Male ; Female ; Child ; Adolescent
Language	English
Publishing date	2023-01-18
Publishing country	Denmark
Document type	Journal Article
ZDB-ID	353721-3
ISSN	1399-0020 ; 0901-5027
ISSN (online)	1399-0020
ISSN	0901-5027
DOI	10.1016/j.ijom.2023.01.003
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Zs.A 931: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: In Reply.

Isomura, E T / Matsukawa, M / Yokota, Y / Tanaka, N / Fujii, N / Nohara, K

International journal of oral and maxillofacial surgery

2023 Volume 53, Issue 4, Page(s) 352–353

Language	English
Publishing date	2023-10-17
Publishing country	Denmark
Document type	Letter
ZDB-ID	353721-3
ISSN	1399-0020 ; 0901-5027
ISSN (online)	1399-0020
ISSN	0901-5027
DOI	10.1016/j.ijom.2023.10.003
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Zs.A 931: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Conference proceedings ; Online: Another implementation of GARPOS-MCMC for the full-Bayes GNSS-A seafloor precise positioning analysis with the widely applicable Bayesian information criterion

Watanabe, S. / Ishikawa, T. / Nakamura, Y. / Nagae, K. / Yokota, Y.

XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)

2023

Abstract: As one of the seafloor geodetic techniques, precise seafloor positioning by the GNSS—Acoustic ranging combination technique (GNSS-A) is applied for the observations of the crustal deformation in the plate subduction zones (e.g., Spiess et al., 1998; ... ...

Abstract	As one of the seafloor geodetic techniques, precise seafloor positioning by the GNSS—Acoustic ranging combination technique (GNSS-A) is applied for the observations of the crustal deformation in the plate subduction zones (e.g., Spiess et al., 1998; Fujita et al., 2006). For the precise positioning with the GNSS-A, it is required to appropriately cancel or correct the effects of sound speed variation on acoustic travel time. We have developed static GNSS-A analysis methods where the sound speed effects were simultaneously corrected with well-distributed acoustic data, by introducing the perturbation field model (Watanabe et al., 2020). Based on the empirical Bayes approach, it was implemented in an open-source software GARPOS (the latest version is v1.0.1, https://doi.org/10.5281/zenodo.6414642), in which hyperparameters are selected to minimize the Akaike Bayesian Information Criterion (ABIC; Akaike, 1980). Watanabe et al. (under review, preprint https://doi.org/10.21203/rs.3.rs-1881756/v1) developed the upgraded version of GARPOS, i.e., GARPOS-MCMC (the latest version is v1.0.0, https://doi.org/10.5281/zenodo.6825238), with a full-Bayes GNSS-A analysis scheme, where the hyperparameters are also expressed as probability density functions. The parameters are estimated with the Markov chain Monte Carlo method, which enabled us to directly sample from the joint posterior of parameters including any hyperparameters and evaluate the correlations between those parameters. However, it requires computational resources as the number of acoustic data becomes large. To overcome the disadvantage, we introduced the widely applicable Bayesian information criterion (WBIC; Watanabe, 2013) for model selection for some hyperparameters, to partly take an empirical Bayes approach, and implemented it on GARPOS-MCMC.
Subject code	310
Language	English
Publishing country	de
Document type	Conference proceedings ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Conference proceedings ; Online: Japan Coast Guard's GNSS-A seafloor crustal deformation observation and the data strategy

Nakamura, Y. / Ishikawa, T. / Watanabe, S. / Nagae, K. / Yokota, Y.

XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)

2023

Abstract: Around the Japanese Islands, major subduction zones along the plate boundaries of the Pacific Plate and the Philippine Sea Plate have repeatedly caused megathrust earthquakes. GNSS-Acoustic ranging combination technique (GNSS-A) is an effective tool to ... ...

Abstract	Around the Japanese Islands, major subduction zones along the plate boundaries of the Pacific Plate and the Philippine Sea Plate have repeatedly caused megathrust earthquakes. GNSS-Acoustic ranging combination technique (GNSS-A) is an effective tool to measure the absolute position on the seafloor, from which we can visualize the plate boundary conditions at these subduction zones. The Japan Coast Guard has been conducting GNSS-A observations at the sites deployed along the Japan Trench and the Nankai Trough, named the Seafloor Geodetic Observation Array (SGO-A). At the SGO-A sites, we have been periodically conducting campaign observations for approximately 20 years. In these two decades, technological advancements in our observation and analysis techniques have enabled us to detect shallow slow slip events lasting for a year (Yokota and Ishikawa 2020). Our decadal observations have revealed the processes related to the 2011 Tohoku-oki Earthquake (Watanabe et al. 2021). We have also been developing a csv-based data format for GNSS-A observation data, which we have been discussing in a working group of the Inter-commission Committee on Marine Geodesy (ICCM) of the International Association of Geodesy (IAG).
Language	English
Publishing country	de
Document type	Conference proceedings ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Conference proceedings ; Online: Advancement of accuracy and frequency of the GNSS-A seafloor crustal deformation observation

Yokota, Y. / Ishikawa, T. / Watanabe, S. / Nakamura, Y. / Nagae, K.

XXVIII General Assembly of the International Union of Geodesy and Geophysics (IUGG)

2023

Abstract: Although GNSS-A (Global Navigation Satellite System–Acoustic ranging combination technique) observation is a technology that measures steady or sudden seafloor crustal deformations at the centimeter level, the technical capabilities are inferior to those ...

Abstract	Although GNSS-A (Global Navigation Satellite System–Acoustic ranging combination technique) observation is a technology that measures steady or sudden seafloor crustal deformations at the centimeter level, the technical capabilities are inferior to those of terrestrial GNSS observation in terms of accuracy and frequency. Therefore, many technological developments are currently underway. We are conducting error factor analysis through simulation and experimental research in order to improve the observation accuracy and frequency of SGO-A, which is operated by the Japan Coast Guard. By investigating the effects of high-rate GNSS on GNSS-A, development of representation and modeling methods of underwater sound speed fields, and equipment and angle-dependent characteristics due to sonar characteristics, we are progressing in developing quantitative evaluation and correction methods for errors. The accuracy research of GNSS-A is closely related to the accuracy research of GNSS. In the near future, we would like to construct a unified error correction method for instruments and observation envirnments, similar to GNSS. Regarding the observation frequency, we have reached the limit of observation frequency using ships around 2020, and the development of new sea surface platforms is necessary. For example, research on autonomous buoys (wave glider), moored buoys, and flying-boat type UAVs is underway. Various marine engineering applications other than GNSS-A are underway for a research field of sea surface platforms, and this field may be further updated in the future. In this presentation, we will also discuss new sea surface platforms for GNSS-A.
Subject code	620
Language	English
Publishing country	de
Document type	Conference proceedings ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Long-term effects of anti-

Hirose, Satoshi / Hara, Makoto / Yokota, Yuki / Nakajima, Hideto

Frontiers in neurology

2023 Volume 14, Page(s) 1170961

Abstract: Background: Patients with anti-: Methods: Data collected via structured self-reported questionnaires included clinical features, long-term outcomes, and QOL. These questionnaires were administered to adult members of the Japanese Anti-NMDARE Patients' ...

Abstract	Background: Patients with anti- Methods: Data collected via structured self-reported questionnaires included clinical features, long-term outcomes, and QOL. These questionnaires were administered to adult members of the Japanese Anti-NMDARE Patients' Association. We used the NeuroQOL battery to assess QOL in physical, mental, and social domains. Raw NeuroQOL scores were converted to T-scores for comparison with controls. Results: Twenty-two patients completed the questionnaire. The median interval between disease onset and questionnaire response was 78 months. Forty-six percent of patients reported persistent sequelae, with only 73% able to resume prior work/school activities. Although patients' Global QOL was similar to controls, patients with NMDARE had significantly worse social QOL. Patients with worse social QOL had more frequent sequelae than those with better social QOL. Furthermore, patients with persistent sequelae had significantly worse Global QOL than those without sequelae and controls. Conclusion: Patients with NMDARE had worse social QOL than controls. Given the adverse effects of disease sequelae on QOL, treatment strategies that minimize sequelae during the acute-phase may improve patients' QOL, even years post-disease onset.
Language	English
Publishing date	2023-05-18
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2564214-5
ISSN	1664-2295
ISSN	1664-2295
DOI	10.3389/fneur.2023.1170961
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Article: Editorial: Rising stars in virology: 2022.

Tsunetsugu-Yokota, Yasuko / Magiorkinis, Gkikas / Kimura, Hirokazu

Frontiers in microbiology

2023 Volume 14, Page(s) 1205877

Language	English
Publishing date	2023-05-30
Publishing country	Switzerland
Document type	Editorial
ZDB-ID	2587354-4
ISSN	1664-302X
ISSN	1664-302X
DOI	10.3389/fmicb.2023.1205877
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Article ; Online: Long-term outcomes and health-related quality of life in patients with autoimmune encephalitis: An observational study.

Yokota, Yuki / Hirose, Satoshi / Hara, Makoto / Nakajima, Hideto

Medicine

2023 Volume 102, Issue 40, Page(s) e35162

Abstract: Autoimmune encephalitis (AE) subacutely causes severe and multiple symptoms; however, most patients achieve neurologically favorable outcomes. Despite the substantial recovery in motor function, persistent impairments in mental/social aspects lasting for ...

Abstract	Autoimmune encephalitis (AE) subacutely causes severe and multiple symptoms; however, most patients achieve neurologically favorable outcomes. Despite the substantial recovery in motor function, persistent impairments in mental/social aspects lasting for several years have been recognized, and its potential effect on health-related quality of life (HRQOL) has been argued. To urgently evaluate the long-term effects of AE on patients' HRQOL, we investigated patient-oriented long-term outcomes and assessed the HRQOL of patients with AE. Data of patients who were diagnosed with probable/definite AE, defined by Graus AE criteria 2016, and treated at our hospital between January 2011 and October 2020 were retrospectively retrieved. Their long-term (≥2 years) outcomes, which included various sequelae and handicaps in social activities such as returning to previous work/school life through structured interview forms, were evaluated, and the HRQOL was assessed using Neuro-QOL battery. We identified 32 patients who met the Graus AE criteria 2016 and eventually enrolled 21 patients in the study. The median interval between disease onset and survey period was 63 (25-156) months, and 43% of the patients had persistent neuropsychiatric symptoms, including memory disorders, personality changes, and seizures. No more than 71% returned to their previous work/school life. Although most of the patients had global QOL within normal limits, 48% had social QOL under normal limits. Patients with sequelae were significantly less likely to return to previous work/school and had worse global/social quality of life than patients without sequelae. In conclusion, nearly half of patients with AE had social QOL under normal limits 5 years after onset. The difficulty in returning to work/school and a worse HRQOL were notable in patients with sequelae.
MeSH term(s)	Humans ; Quality of Life ; Retrospective Studies ; Encephalitis ; Disease Progression ; Autoimmune Diseases of the Nervous System
Language	English
Publishing date	2023-10-06
Publishing country	United States
Document type	Observational Study ; Journal Article
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000035162
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