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  1. AU="Yoo, Jiwoon"
  2. AU="Davis, Sangeetha P"
  3. AU="Groesdonk, H."
  4. AU=Calorini Lido AU=Calorini Lido
  5. AU="Marina Umansky Sommer"
  6. AU="Al-Yousofy, Fayed"
  7. AU="Martínez-Peláez, Rafael"
  8. AU="Joumaa, Ranim"
  9. AU="Miranda, Alejandro"
  10. AU="Asselin, Yanick"
  11. AU="Napierala, Eric"
  12. AU="Hanna, S R"
  13. AU=Klukova Ludmila
  14. AU="Androutsakos, Theodoros"
  15. AU="Vrzal, Radim"
  16. AU="Carlo Gambacorti-Passerini"
  17. AU="Mahjabeen, Faria"
  18. AU="Roberto Giovannoni"
  19. AU="Rajendra Damu Patil"
  20. AU="Santos-García, Irene"
  21. AU="Josiah Willock, Robina"
  22. AU="Ciacci, Joseph"
  23. AU="Barker, A"
  24. AU="Chris Baraloto"
  25. AU="Wagner, Lloyd"
  26. AU="Jandrić, Petar Hayes"

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  1. Artikel ; Online: Formulating Cybersecurity Requirements for Autonomous Ships Using the SQUARE Methodology.

    Yoo, Jiwoon / Jo, Yonghyun

    Sensors (Basel, Switzerland)

    2023  Band 23, Heft 11

    Abstract: Artificial intelligence (AI) technology is crucial for developing autonomous ships in the maritime industry. Autonomous ships, based on the collected information, recognize the environment without any human intervention and operate themselves using their ...

    Abstract Artificial intelligence (AI) technology is crucial for developing autonomous ships in the maritime industry. Autonomous ships, based on the collected information, recognize the environment without any human intervention and operate themselves using their own judgment. However, ship-to-land connectivity increased, owing to the real-time monitoring and remote control (for unexpected circumstances) from land; this poses a potential cyberthreat to various data collected inside and outside the ships and to the applied AI technology. For the safety of autonomous ships, cybersecurity around AI technology needs to be considered, in addition to the cybersecurity of the ship systems. By identifying various vulnerabilities and via research cases of the ship systems and AI technologies, this study presents possible cyberattack scenarios on the AI technologies applied to autonomous ships. Based on these attack scenarios, cyberthreats and cybersecurity requirements are formulated for autonomous ships by employing the security quality requirements engineering (SQUARE) methodology.
    Mesh-Begriff(e) Humans ; Ships ; Artificial Intelligence ; Engineering ; Technology ; Computer Security
    Sprache Englisch
    Erscheinungsdatum 2023-05-24
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23115033
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: A comparison of human cord blood- and embryonic stem cell-derived endothelial progenitor cells in the treatment of chronic wounds

    Park, Soon-Jung / Moon, Sung-Hwan / Lee, Hye-Jin / Lim, Joa-Jin / Kim, Jung-Mo / Seo, Joseph / Yoo, Ji-Woon / Kim, Ok-Jung / Kang, Sun-Woong / Chung, Hyung-Min

    Biomaterials. 2013 Jan., v. 34, no. 4

    2013  

    Abstract: Endothelial progenitor cells (EPCs) promote new blood vessel formation and increase angiogenesis by secreting growth factors and cytokines in ischemic tissues. Therefore, EPCs have been highlighted as an alternative cell source for wound healing. EPCs ... ...

    Abstract Endothelial progenitor cells (EPCs) promote new blood vessel formation and increase angiogenesis by secreting growth factors and cytokines in ischemic tissues. Therefore, EPCs have been highlighted as an alternative cell source for wound healing. EPCs can be isolated from various sources, including the bone marrow, cord blood, and adipose tissue. However, several recent studies have reported that isolating EPCs from these sources has limitations, such as the isolation of insufficient cell numbers and the difficulty of expanding these cells in culture. Thus, human embryonic stem cells (hESCs) have generated great interest as an alternative source of EPCs. Previously, we established an efficient preparation method to obtain EPCs from hESCs (hESC-EPCs). These hESC-EPCs secreted growth factors and cytokines, which are known to be important in angiogenesis and wound healing. In this study, we directly compared the capacity of hESC-EPCs and human cord blood-derived EPCs (hCB-EPCs) to benefit wound healing. The number of hESC-EPCs increased during culture and was always higher than the number of hCB-EPCs during the culture period. In addition, the levels of VEGF and Ang-1 secreted by hESC-EPCs were significantly higher than those produced by hCB-EPCs. After transplantation in a mouse dermal excisional wound model, all EPC-transplanted wounds exhibited better regeneration than in the control group. More importantly, we found that the wounds transplanted with hESC-EPCs showed significantly accelerated re-epithelialization. Thus, hESC-EPCs may be a promising cell source for the treatment of chronic wounds.
    Schlagwörter adipose tissue ; angiogenesis ; blood ; blood vessels ; bone marrow ; cytokines ; embryonic stem cells ; humans ; mice ; models ; tissue repair ; vascular endothelial growth factors
    Sprache Englisch
    Erscheinungsverlauf 2013-01
    Umfang p. 995-1003.
    Erscheinungsort Elsevier Ltd
    Dokumenttyp Artikel
    ZDB-ID 603079-8
    ISSN 0142-9612
    ISSN 0142-9612
    DOI 10.1016/j.biomaterials.2012.10.039
    Datenquelle NAL Katalog (AGRICOLA)

    Volltext online

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    Verfügbar in ZB MED Köln/Königswinter

    Zs.B 2371: Hefte anzeigen Standort:
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  3. Artikel ; Online: A comparison of human cord blood- and embryonic stem cell-derived endothelial progenitor cells in the treatment of chronic wounds.

    Park, Soon-Jung / Moon, Sung-Hwan / Lee, Hye-Jin / Lim, Joa-Jin / Kim, Jung-Mo / Seo, Joseph / Yoo, Ji-Woon / Kim, Ok-Jung / Kang, Sun-Woong / Chung, Hyung-Min

    Biomaterials

    2013  Band 34, Heft 4, Seite(n) 995–1003

    Abstract: Endothelial progenitor cells (EPCs) promote new blood vessel formation and increase angiogenesis by secreting growth factors and cytokines in ischemic tissues. Therefore, EPCs have been highlighted as an alternative cell source for wound healing. EPCs ... ...

    Abstract Endothelial progenitor cells (EPCs) promote new blood vessel formation and increase angiogenesis by secreting growth factors and cytokines in ischemic tissues. Therefore, EPCs have been highlighted as an alternative cell source for wound healing. EPCs can be isolated from various sources, including the bone marrow, cord blood, and adipose tissue. However, several recent studies have reported that isolating EPCs from these sources has limitations, such as the isolation of insufficient cell numbers and the difficulty of expanding these cells in culture. Thus, human embryonic stem cells (hESCs) have generated great interest as an alternative source of EPCs. Previously, we established an efficient preparation method to obtain EPCs from hESCs (hESC-EPCs). These hESC-EPCs secreted growth factors and cytokines, which are known to be important in angiogenesis and wound healing. In this study, we directly compared the capacity of hESC-EPCs and human cord blood-derived EPCs (hCB-EPCs) to benefit wound healing. The number of hESC-EPCs increased during culture and was always higher than the number of hCB-EPCs during the culture period. In addition, the levels of VEGF and Ang-1 secreted by hESC-EPCs were significantly higher than those produced by hCB-EPCs. After transplantation in a mouse dermal excisional wound model, all EPC-transplanted wounds exhibited better regeneration than in the control group. More importantly, we found that the wounds transplanted with hESC-EPCs showed significantly accelerated re-epithelialization. Thus, hESC-EPCs may be a promising cell source for the treatment of chronic wounds.
    Mesh-Begriff(e) Animals ; Cell Differentiation ; Cell Line ; Chronic Disease ; Cord Blood Stem Cell Transplantation/methods ; Embryonic Stem Cells/cytology ; Embryonic Stem Cells/transplantation ; Endothelial Cells/cytology ; Endothelial Cells/transplantation ; Humans ; Male ; Mice ; Mice, Nude ; Treatment Outcome ; Wound Healing ; Wounds, Penetrating/pathology ; Wounds, Penetrating/surgery
    Sprache Englisch
    Erscheinungsdatum 2013-01
    Erscheinungsland Netherlands
    Dokumenttyp Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 603079-8
    ISSN 1878-5905 ; 0142-9612
    ISSN (online) 1878-5905
    ISSN 0142-9612
    DOI 10.1016/j.biomaterials.2012.10.039
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

    Volltext online

    Zusatzmaterialien

    Kategorien

    Verfügbar in ZB MED Köln/Königswinter

    Zs.B 2371: Hefte anzeigen Standort:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Über subito bestellen

    Dieser Service ist kostenpflichtig (siehe Lieferbedingungen von subito). Bestellungen, die einen Artikel nebst Supplementary Material umfassen, werden grundsätzlich wie mehrfache Bestellungen bearbeitet. Gebühren fallen in diesen Fällen für jede einzelne Bestellung an.

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