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  1. Article ; Online: Data Acquisition Control for UAV-Enabled Wireless Rechargeable Sensor Networks.

    Yoon, Ikjune

    Sensors (Basel, Switzerland)

    2023  Volume 23, Issue 7

    Abstract: In the realm of Internet of Things (IoT), wireless sensor networks (WSNs) have been the subject of ongoing research into the use of energy harvesting to capture ambient energy, and wireless power transfer (WPT) via a mobile charger to overcome the energy ...

    Abstract In the realm of Internet of Things (IoT), wireless sensor networks (WSNs) have been the subject of ongoing research into the use of energy harvesting to capture ambient energy, and wireless power transfer (WPT) via a mobile charger to overcome the energy limitations of sensors. Moreover, to mitigate energy imbalance and reduce the number of hops, strategies have been developed to leverage cars or unmanned aerial vehicles (UAVs) as mobile sinks. The primary objective of this work is to increase network lifetime by reducing energy consumption of hotspot nodes and increasing the amount of data acquired from all sensors in an environment that combines the methods mentioned above.To achieve this objective, the proposed method involves developing multiple minimum depth trees (MDTs) for all nodes, considering the energy of the UAV and sensor nodes. Parent nodes prevent their own energy depletion and ensure data transmission without imbalance by adaptively controlling the data sensed at the nodes and their child nodes. Consequently, the energy depletion of nodes in hotspots is prevented, more sensory data is acquired, and balanced data collection from all nodes is achieved. Simulation results demonstrate that the proposed scheme outperforms other state-of-the-art methods in terms of reduced energy depletion, increased network connectivity, and the amount of data collected at the sink node. This scheme will be applied to applications that collect environmental data outdoors, such as climate measurement, to collect data uniformly and increase the lifespan of the network, thereby reducing network maintenance costs while collecting data effectively.
    Language English
    Publishing date 2023-03-29
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s23073582
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Voter Registration in the United States: A Call for Change.

    Yoon, Intae / Ames, Natalie

    Social work

    2023  Volume 69, Issue 1, Page(s) 99–102

    MeSH term(s) Humans ; United States ; Voting ; Social Work ; Politics
    Language English
    Publishing date 2023-11-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 410783-4
    ISSN 1545-6846 ; 0037-8046
    ISSN (online) 1545-6846
    ISSN 0037-8046
    DOI 10.1093/sw/swad043
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Sustainable animal agriculture in the United States and the implication in Republic of Korea.

    Yoon, Inkuk / Oh, Sang-Hyon / Kim, Sung Woo

    Journal of animal science and technology

    2024  Volume 66, Issue 2, Page(s) 279–294

    Abstract: Agriculture has played a significant role in the national economy, contributing to food security, driving economic growth, and safeguarding the dietary habits of the population. Korean agriculture has been compelled to focus on intensive farming due to ... ...

    Abstract Agriculture has played a significant role in the national economy, contributing to food security, driving economic growth, and safeguarding the dietary habits of the population. Korean agriculture has been compelled to focus on intensive farming due to its limited cultivation area, excessive input costs, and the limitations of agricultural mechanization. In the Republic of Korea (R.O.K), the concept of environmentally friendly animal agriculture began to be introduced in the early 2000s. This concept ultimately aims to cultivate sustainable animal agriculture (SAA) through environmentally friendly production practices, ensuring the healthy rearing of animals to supply safe animal products. Despite the government's efforts, there are still significant challenges in implementing environmentally friendly agriculture and SAA in the R.O.K. Therefore, the objective of this review is to establish the direction that the animal agriculture sector should take in the era of climate crisis, and to develop effective strategies for SAA tailored to the current situation in the R.O.K by examining the trends in SAA in the U.S. The animal agriculture sector in the U.S. has been working towards creating a SAA system where humans, animals, and the environment can coexist through government initiatives, industry research, technological support, and individual efforts. Efforts have been made to reduce emissions like carbon, and improve factors affecting the environment such as the carbon footprint, odor, and greenhouse gases associated with animal agriculture processes for animals such as cattle and pigs. The transition of the U.S. towards SAA appears to be driven by both external goals related to addressing climate change and the primary objectives of responding to the demand for safe animal products, expanding consumption, and securing competitiveness in overseas export markets. The demand for animal welfare, organic animal products, and processed goods has been increasing in the U.S. consumer market. A major factor in the transformation of the U.S. animal agriculture sector in terms of livestock specifications is attributed to environmentally friendly practices such as high-quality feed, heat stress reduction, improvements in reproductive ability and growth period reduction, and efforts in animal genetic enhancement.
    Language English
    Publishing date 2024-03-31
    Publishing country Korea (South)
    Document type Journal Article ; Review
    ZDB-ID 2775231-8
    ISSN 2055-0391
    ISSN 2055-0391
    DOI 10.5187/jast.2024.e19
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Blood-inspired random bit generation using microfluidics system.

    Yoon, Inkwon / Han, Jong Hyeok / Park, Byeong Uk / Jeon, Hee-Jae

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 7474

    Abstract: The development of random number generators (RNGs) using speckle patterns is pivotal for secure encryption key generation, drawing from the recent statistical properties identified in speckle-based imaging. Speckle-based RNG systems generate a sequence ... ...

    Abstract The development of random number generators (RNGs) using speckle patterns is pivotal for secure encryption key generation, drawing from the recent statistical properties identified in speckle-based imaging. Speckle-based RNG systems generate a sequence of random numbers through the unpredictable and reproducible nature of speckle patterns, ensuring a source of randomness that is independent of algorithms. However, to guarantee their effectiveness and reliability, these systems demand a meticulous and rigorous approach. In this study, we present a blood-inspired RNG system with a microfluidics device, designed to generate random numbers at a rate of 5.5 MHz and a high-speed of 1250 fps. This process is achieved by directing a laser beam through a volumetric scattering medium to procure speckle patterns. Additionally, designed microfluidic device requires only a minimal blood sample of 5 µl to capture these speckle patterns effectively. After implementing the two-pass tuple-output von Neumann debiasing algorithm to counteract statistical biases, we utilized the randomness statistical test suite from the National Institute of Standards and Technology for validation. The generated numbers successfully passed these tests, ensuring their randomness and unpredictability. Our blood-inspired RNG, utilizing whole blood, offers a pathway for affordable, high-output applications in fields like encryption, computer security, and data protection.
    Language English
    Publishing date 2024-03-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-58088-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The Effect of the SEI Layer Mechanical Deformation on the Passivity of a Si Anode in Organic Carbonate Electrolytes.

    Yoon, Insun / Larson, Jonathan M / Kostecki, Robert

    ACS nano

    2023  Volume 17, Issue 7, Page(s) 6943–6954

    Abstract: The solid electrolyte interphase (SEI) on a Si negative electrode in carbonate-based organic electrolytes shows intrinsically poor passivating behavior, giving rise to unsatisfactory calendar life of Li-ion batteries. Moreover, mechanical strains induced ...

    Abstract The solid electrolyte interphase (SEI) on a Si negative electrode in carbonate-based organic electrolytes shows intrinsically poor passivating behavior, giving rise to unsatisfactory calendar life of Li-ion batteries. Moreover, mechanical strains induced in the SEI due to large volume changes of Si during charge-discharge cycling could contribute to its mechanical instability and poor passivating behavior. This study elucidates the influence that static mechanical deformation of the SEI has on the rate of unwanted parasitic reactions at the Si/electrolyte interface as a function of electrode potential. The experimental approach involves the utilization of Si thin-film electrodes on substrates with disparate elastic moduli, which either permit or suppress the SEI deformation in response to Si volume changes upon charging-discharging. We find that static mechanical stretching and deformation of the SEI results in an increased parasitic electrolyte reduction current on Si. Furthermore, attenuated total reflection and near-field Fourier-transform infrared nanospectroscopy reveal that the static mechanical stretching and deformation of the SEI fosters a selective transport of linear carbonate solvent through, and nanoconfinement within, the SEI. These, in turn, promote selective solvent reduction and continuous electrolyte decomposition on Si electrodes, reducing the calendar life of Si anode-based Li-ion batteries. Finally, possible correlations between the structure and chemical composition of the SEI layer and its mechanical and chemical resilience under prolonged mechanical deformation are discussed in detail.
    Language English
    Publishing date 2023-03-27
    Publishing country United States
    Document type Journal Article
    ISSN 1936-086X
    ISSN (online) 1936-086X
    DOI 10.1021/acsnano.3c00724
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Disease association and therapeutic routes of aminoacyl-tRNA synthetases.

    Yoon, Ina / Kim, Uijoo / Choi, Jaeyoung / Kim, Sunghoon

    Trends in molecular medicine

    2023  Volume 30, Issue 1, Page(s) 89–105

    Abstract: Aminoacyl-tRNA synthetases (ARSs) are enzymes that catalyze the ligation of amino acids to tRNAs for translation. Beyond their traditional role in translation, ARSs have acquired regulatory functions in various biological processes (epi-translational ... ...

    Abstract Aminoacyl-tRNA synthetases (ARSs) are enzymes that catalyze the ligation of amino acids to tRNAs for translation. Beyond their traditional role in translation, ARSs have acquired regulatory functions in various biological processes (epi-translational functions). With their dual-edged activities, aberrant expression, secretion, and mutations of ARSs are associated with human diseases, including cancer, autoimmune diseases, and neurological diseases. The increasing numbers of newly unveiled activities and disease associations of ARSs have spurred interest in novel drug development, targeting disease-related catalytic and noncatalytic activities of ARSs as well as harnessing ARSs as sources for biological therapeutics. This review speculates how the translational and epi-translational activities of ARSs can be related and describes how their activities can be linked to diseases and drug discovery.
    MeSH term(s) Humans ; Amino Acyl-tRNA Synthetases/genetics ; Amino Acyl-tRNA Synthetases/metabolism ; RNA, Transfer/genetics ; RNA, Transfer/metabolism
    Chemical Substances Amino Acyl-tRNA Synthetases (EC 6.1.1.-) ; RNA, Transfer (9014-25-9)
    Language English
    Publishing date 2023-11-08
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2036490-8
    ISSN 1471-499X ; 1471-4914
    ISSN (online) 1471-499X
    ISSN 1471-4914
    DOI 10.1016/j.molmed.2023.10.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Ex vivo photothermal treatment-induced immunogenic cell death for anticancer vaccine development.

    Yu, Su Hyun / Yoon, Il / Kim, Yeon-Jeong

    International immunopharmacology

    2023  Volume 127, Page(s) 111450

    Abstract: Photothermal therapy is an anti-cancer strategy that induce cell death by converting light energy into heat energy. During photothermal therapy, cancer cells were treated with photothermal agents, such as indocyanine green, and irradiated with a laser. ... ...

    Abstract Photothermal therapy is an anti-cancer strategy that induce cell death by converting light energy into heat energy. During photothermal therapy, cancer cells were treated with photothermal agents, such as indocyanine green, and irradiated with a laser. Heat stress in cancer cells results in cellular death and inflammatory responses. In the present study, we demonstrated how ex vivo photothermal (PT)-treated cells underwent immunogenic cell death. PT treatment caused significant expression of heat shock protein (HSP) 27, HSP70, and HSP90 in murine tumor cells. To evaluate the immunogenicity of heat-stressed cells, lysate from PT-treated tumor cells or water-based heated cells was pulsed to syngeneic bone-marrow-derived dendritic cells (DCs) to generate a DC-based vaccine. Administration with PT-treated tumor lysates-pulsed DC vaccine resulted in significant inhibition of tumor growth in BALB/c and C57BL/6 syngeneic tumor-bearing mice. The immunogenicity of PT-treated cancer cells was reduced in the presence of HSP inhibitors, J2, VER-155008 or 17-AAG. Our study elucidates how PT techniques have distinct mechanisms from water-based heating and might be a potentially robust and efficient solution to developing an anti-cancer vaccine.
    MeSH term(s) Animals ; Mice ; Mice, Inbred C57BL ; Immunogenic Cell Death ; Neoplasms/therapy ; Neoplasms/pathology ; Vaccines ; Water ; Dendritic Cells ; Cell Line, Tumor ; Cancer Vaccines
    Chemical Substances Vaccines ; Water (059QF0KO0R) ; Cancer Vaccines
    Language English
    Publishing date 2023-12-28
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2043785-7
    ISSN 1878-1705 ; 1567-5769
    ISSN (online) 1878-1705
    ISSN 1567-5769
    DOI 10.1016/j.intimp.2023.111450
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Effects of feeding

    Klopp, R N / Centeno-Martinez, R E / Yoon, I / Johnson, T A / Boerman, J P

    JDS communications

    2022  Volume 3, Issue 3, Page(s) 174–179

    Abstract: It is essential to reduce antibiotic use in the livestock industry, which leads to a need for alternatives to antibiotics that reduce illness and promote growth in dairy calves. The objective of this study was to evaluate the effect of feeding dairy ... ...

    Abstract It is essential to reduce antibiotic use in the livestock industry, which leads to a need for alternatives to antibiotics that reduce illness and promote growth in dairy calves. The objective of this study was to evaluate the effect of feeding dairy calves
    Language English
    Publishing date 2022-03-16
    Publishing country United States
    Document type Journal Article
    ISSN 2666-9102
    ISSN (online) 2666-9102
    DOI 10.3168/jdsc.2021-0172
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Feeding a Saccharomyces cerevisiae fermentation product during a gut barrier challenge in lactating Holstein cows impacts the ruminal microbiota and metabolome.

    Jiang, Qianming / Sherlock, Danielle N / Elolimy, Ahmed A / Yoon, Ilkyu / Loor, Juan J

    Journal of dairy science

    2024  

    Abstract: Through its influence on the gut microbiota, feeding of Saccharomyces cerevisiae fermentation products (SCFP) has been a successful strategy to enhance the health of dairy cows during periods of physiological stresses. Although production and metabolic ... ...

    Abstract Through its influence on the gut microbiota, feeding of Saccharomyces cerevisiae fermentation products (SCFP) has been a successful strategy to enhance the health of dairy cows during periods of physiological stresses. Although production and metabolic outcomes from feeding SCFP are well-known, combined impacts on the ruminal microbiota and metabolome during gut barrier challenges remain unclear. To address this gap in knowledge, multiparous Holstein cows (97.1 ± 7.6 DIM; n = 8/group) fed a control diet (CON) or CON plus 19 g/d SCFP for 9 wk were subjected to a feed restriction (FR) challenge for 5 d, during which they were fed 40% of their ad-libitum intake from the 7 d before FR. DNA extracted from ruminal fluid was subjected to PacBio Full-Length 16S rRNA gene sequencing, RT-PCR of 12 major ruminal bacteria, and metabolomics analysis of up to 189 metabolites via GC-MS. High-quality amplicon sequence analyses were performed with Targeted Amplicon Diversity Analysis (TADA), MicrobiomeAnalyst, PICRUSt2, and STAMP software, while metabolomics data were analyzed via MetaboAnalyst 5.0. Ruminal fluid metabolites from the SCFP group exhibited a greater α diversity Chao 1 (P = 0.03) and Shannon indices (P = 0.05), and the PLS-DA analysis clearly discriminated metabolite profiles between dietary groups. The abundance of CPla_4_termite_group, Candidatus_Saccharimonas, Oribacterium, and Pirellula genus in cows fed SCFP was greater. In the SCFP group, concentrations of ethanolamine, 2-amino-4,6-dihydroxypyrimidine, glyoxylic acid, serine, threonine, cytosine, stearic acid, and pyrrole-2-carboxylic acid were greater in ruminal fluid. Both Fretibacterium and Succinivibrio abundance were positively correlated with metabolites across various biological processes: gamma-aminobutyric acid, galactose, butane-2,3-diol, fructose, 5-amino pentanoic acid, β-aminoisobutyric acid, ornithine, malonic acid, 3-hydroxy-3-methylbutyric acid, hexanoic acid, heptanoic acid, cadaverine, glycolic acid, β-alanine, 2-hydroxybutyric acid, methyl alanine, and alanine. In the SCFP group, compared with CON, the mean proportion of 14 predicted pathways based on metabolomics data was greater, while 10 predicted pathways were lower. Integrating metabolites and upregulated predicted enzymes (NADP+-dependent glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, serine: glyoxylate aminotransferase, and D-glycerate 3-kinase) indicated that the pentose phosphate pathway and photorespiration pathway were most upregulated by SCFP. Overall, SCFP during FR led to alterations in ruminal microbiota composition and key metabolic pathways. Among those, there was a shift from the tricarboxylic acid (TCA) cycle to the glyoxylate cycle and nitrogenous base production was enhanced.
    Language English
    Publishing date 2024-02-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 242499-x
    ISSN 1525-3198 ; 0022-0302
    ISSN (online) 1525-3198
    ISSN 0022-0302
    DOI 10.3168/jds.2023-24147
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: 3C methods in cancer research: recent advances and future prospects.

    Yoon, Insoo / Kim, Uijin / Song, Yousuk / Park, Taesoo / Lee, Dong-Sung

    Experimental & molecular medicine

    2024  Volume 56, Issue 4, Page(s) 788–798

    Abstract: In recent years, Hi-C technology has revolutionized cancer research by elucidating the mystery of three-dimensional chromatin organization and its role in gene regulation. This paper explored the impact of Hi-C advancements on cancer research by delving ... ...

    Abstract In recent years, Hi-C technology has revolutionized cancer research by elucidating the mystery of three-dimensional chromatin organization and its role in gene regulation. This paper explored the impact of Hi-C advancements on cancer research by delving into high-resolution techniques, such as chromatin loops, structural variants, haplotype phasing, and extrachromosomal DNA (ecDNA). Distant regulatory elements interact with their target genes through chromatin loops. Structural variants contribute to the development and progression of cancer. Haplotype phasing is crucial for understanding allele-specific genomic rearrangements and somatic clonal evolution in cancer. The role of ecDNA in driving oncogene amplification and drug resistance in cancer cells has also been revealed. These innovations offer a deeper understanding of cancer biology and the potential for personalized therapies. Despite these advancements, challenges, such as the accurate mapping of repetitive sequences and precise identification of structural variants, persist. Integrating Hi-C with multiomics data is key to overcoming these challenges and comprehensively understanding complex cancer genomes. Thus, Hi-C is a powerful tool for guiding precision medicine in cancer research and treatment.
    MeSH term(s) Humans ; Neoplasms/genetics ; Neoplasms/pathology ; Chromatin/genetics ; Chromatin/metabolism ; Genomics/methods ; Animals ; Precision Medicine/methods
    Chemical Substances Chromatin
    Language English
    Publishing date 2024-04-25
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 1328915-9
    ISSN 2092-6413 ; 1226-3613 ; 0378-8512
    ISSN (online) 2092-6413
    ISSN 1226-3613 ; 0378-8512
    DOI 10.1038/s12276-024-01236-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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