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Article ; Conference proceedings: Diagnostic accuracy of probe-based confocal laser endomicroscopy and narrow band imaging in detection of gastric neoplasia

Yoon, J. H. / Lee, S. K.

2023 Volume 55, Issue S 02

Event/congress	ESGE Days 2023, Dublin, Ireland, 2023-04-20
Language	English
Publishing date	2023-04-01
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	80120-3
ISSN	1438-8812 ; 0013-726X
ISSN (online)	1438-8812
ISSN	0013-726X
DOI	10.1055/s-0043-1765673
Database	Thieme publisher's database

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Article: Artificial Intelligence in Critical Care Medicine

Yoon, J. H. / Pinsky, M. R. / Clermont, G.

Annual update in intensive care and emergency medicine

2022 Volume -, Issue -, Page(s) 353

Language	English
Document type	Article
ZDB-ID	2600427-6
ISSN	2191-5709
Database	Current Contents Medicine

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Article: Association between the use of electronic cigarettes and the prevalence of chronic rhinosinusitis and allergic rhinitis: a nationwide cross-sectional study.

Rha, M-S / Cho, H-J / Yoon, J-H / Kim, C-H

Rhinology

2021 Volume 60, Issue 1, Page(s) 20–28

Abstract: Background: Whether the use of electronic cigarettes (ECs) is associated with upper airway diseases, including chronic rhinosinusitis (CRS) and allergic rhinitis (AR), remains unclear.: Methods: We analyzed data from the nationwide cross-sectional ... ...

Abstract	Background: Whether the use of electronic cigarettes (ECs) is associated with upper airway diseases, including chronic rhinosinusitis (CRS) and allergic rhinitis (AR), remains unclear. Methods: We analyzed data from the nationwide cross-sectional surveys: the Korea National Health and Nutrition Examination Survey VI (2013-2015), VII (2016-2018), and VIII (2019). Logistic regression analysis was performed to assess the association between EC use and CRS or AR. Results: Among a total of 38,413 participants, 6.4% were former EC users and 2.5% were current EC users. Former EC users and current EC showed a significantly increased OR for CRS or AR compared with never EC users. In the subgroup analysis, the "current CC (conventional cigarette)-current EC" and the "current CC-formal EC" group had a significantly higher OR for CRS or AR than the "current CC-never EC" group. In addition, former CC smokers who currently use ECs showed a significantly higher OR for AR than former CC smokers without EC use. Conclusions: EC use is significantly associated with a high prevalence of CRS and AR in the adult population. These results indicate that the use of ECs may increase the risk of upper airway disease.
MeSH term(s)	Adult ; Cross-Sectional Studies ; Electronic Nicotine Delivery Systems ; Humans ; Nutrition Surveys ; Prevalence ; Rhinitis, Allergic/epidemiology
Language	English
Publishing date	2021-12-23
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	80336-4
ISSN	0300-0729
ISSN	0300-0729
DOI	10.4193/Rhin21.287
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Association of the human papillomavirus infection with the recurrence of sinonasal inverted papilloma: a systematic review and meta-analysis.

Rha, M-S / Kim, C-H / Yoon, J-H / Cho, H-J

Rhinology

2021 Volume 60, Issue 1, Page(s) 2–10

Abstract: Background: Although the role of human papillomavirus (HPV) in sinonasal inverted papilloma (SNIP) has been investigated, the link between HPV infection and SNIP recurrence remains controversial. This meta-analysis aimed to investigate the association ... ...

Abstract	Background: Although the role of human papillomavirus (HPV) in sinonasal inverted papilloma (SNIP) has been investigated, the link between HPV infection and SNIP recurrence remains controversial. This meta-analysis aimed to investigate the association between HPV infection and recurrence of SNIP. Methods: The PubMed, Web of Science, Google Scholar, and Cochrane Library databases were searched (until 16 June 2021) to collect all relevant articles. The pooled odds ratio (OR) with 95% confidence interval (CI) was calculated using the fixed effects model. In addition, subgroup analysis, assessment of publication bias, and sensitivity analyses were performed. Results: Fourteen eligible articles, including 592 patients with SNIP, were included in this study. Pooled analysis revealed that HPV-positive cases exhibited a significantly higher OR of tumour recurrence than HPV-negative counterparts). A significant association between HPV infection and tumour recurrence remained stable in subgroup analyses according to the publication year of the studies. Conclusions: Our meta-analysis demonstrates that HPV infection is significantly associated with the recurrence of SNIP, suggesting the pathological role of HPV in SNIP. These results suggest that HPV infection should be considered in the management of SNIP.
MeSH term(s)	Humans ; Nose Neoplasms/pathology ; Papilloma, Inverted/pathology ; Papillomaviridae ; Papillomavirus Infections ; Paranasal Sinus Neoplasms/pathology
Language	English
Publishing date	2021-12-22
Publishing country	Netherlands
Document type	Journal Article ; Meta-Analysis ; Systematic Review
ZDB-ID	80336-4
ISSN	0300-0729
ISSN	0300-0729
DOI	10.4193/Rhin21.255
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Article: Gustatory dysfunction in patients with olfactory dysfunction and the associated factors.

Rha, M-S / Cho, H-J / Yoon, J-H / Moon, S J / Kim, C-H

Rhinology

2022 Volume 60, Issue 3, Page(s) 200–206

Abstract: Background: Little is known about the occurrence of gustatory dysfunction (GD) in relation to different aetiologies of olfactory dysfunction (OD) as assessed by psychophysical chemosensory tests. The aim of this study was to analyse gustatory function ... ...

Abstract	Background: Little is known about the occurrence of gustatory dysfunction (GD) in relation to different aetiologies of olfactory dysfunction (OD) as assessed by psychophysical chemosensory tests. The aim of this study was to analyse gustatory function in patients with OD and to investigate clinical factors associated with GD. Methods: A total of 742 individuals who underwent both olfactory and gustatory function tests at a tertiary medical centre from November 2019 to March 2021 were retrospectively enrolled. Olfactory and gustatory function were assessed by the YSK olfactory and gustatory function tests, respectively. Patients with OD were classified into four groups according to the aetiology: sinonasal disease, post-infection OD (PIOD), post-traumatic OD (PTOD), and others. Secondary outcomes included age, sex, smoking history, and alcohol history. Results: Among the 488 patients with OD, 93 (19.1%) showed GD and 395 (80.9%) had normal gustatory function. Only 25 (9.8%) among 254 individuals with normosmia showed GD. Analyses of these frequencies revealed a significant association between OD and GD. In addition, the taste score was significantly lower in patients with OD than individuals with normosmia. The frequency of GD was significantly higher in patients with PTOD (53.6%) than in those with OD of other aetiologies (sinonasal disease, 6.7%; PIOD, 13.0%; others, 24.4%). In the multivariate analysis, age >=5 years and PTOD were associated with a high frequency of GD among patients with OD. Conclusions: The current study show that GD is significantly associated with OD. In particular, GD is more common in patients with PTOD than in those with OD of other aetiologies.
MeSH term(s)	Humans ; Child, Preschool ; Olfaction Disorders ; Retrospective Studies ; Smell ; Taste Disorders/etiology
Language	English
Publishing date	2022-02-16
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	80336-4
ISSN	0300-0729
ISSN	0300-0729
DOI	10.4193/Rhin21.309
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Article: Clinical characteristics and associated factors of qualitative olfactory dysfunction.

Eo, T-S / Lee, H Y / Cho, H-J / Yoon, J-H / Rha, M-S / Kim, C-H

Rhinology

2023 Volume 61, Issue 5, Page(s) 432–440

Abstract: Background: Although interest in qualitative olfactory dysfunction (OD), including parosmia and phantosmia, has been increasing since the COVID-19 pandemic, little is known about the clinical characteristics and associated factors of qualitative OD.: ... ...

Abstract	Background: Although interest in qualitative olfactory dysfunction (OD), including parosmia and phantosmia, has been increasing since the COVID-19 pandemic, little is known about the clinical characteristics and associated factors of qualitative OD. Methods: Adult patients with subjective smell disturbance who underwent both the olfactory questionnaire and psychophysical olfactory function test were retrospectively enrolled. Demographic and clinical characteristics were analysed according to the presence or absence of parosmia or phantosmia. Results: Among a total of 753 patients with self-reported OD, 60 (8%) and 167 (22.2%) patients reported parosmia and phantosmia, respectively. Younger age and female sex were related to both parosmia and phantosmia. The frequency of parosmia was significantly higher in patients with post-viral OD (17.9%) than in patients with the sinonasal disease (5.5%), whereas that of phantosmia was not different according to aetiologies of OD. Patients with COVID-19 had significantly younger ages and higher TDI scores than those with other viral infections. Remarkably, patients with parosmia or phantosmia had significantly higher TDI scores than those without but experienced more disruption in daily life. In the multivariate analysis, younger age and higher TDI score were identified as independent factors associated with both parosmia and phantosmia, while the viral infection was associated with parosmia but not with phantosmia. Conclusions: Patients with OD who have parosmia or phantosmia have higher odour sensitivity than those who do not, but experience more deterioration in the quality of life. Viral infection is a risk factor for parosmia but not for phantosmia.
MeSH term(s)	Adult ; Humans ; Female ; Smell ; Retrospective Studies ; Quality of Life ; Pandemics ; COVID-19/complications ; Olfaction Disorders
Language	English
Publishing date	2023-05-25
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	80336-4
ISSN	0300-0729
ISSN	0300-0729
DOI	10.4193/Rhin23.004
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Conference proceedings: Hemostatic powder versus conventional treatments for malignancy-related upper gastrointestinal bleeding

Yoon, J. H. / Jung, D. H. / Huh, C. W. / Park, J. C. / Shin, S. K. / Lee, S. K. / Lee, Y. C.

Endoscopy

2024 Volume 56, Issue S 02

Event/congress	ESGE Days 2024, Berlin, Germany, 2024-04-25
Language	English
Publishing date	2024-04-01
Publisher	Georg Thieme Verlag KG
Publishing place	Stuttgart ; New York
Document type	Article ; Conference proceedings
ZDB-ID	80120-3
ISSN	1438-8812 ; 0013-726X
ISSN (online)	1438-8812
ISSN	0013-726X
DOI	10.1055/s-0044-1783476
Database	Thieme publisher's database

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Article ; Online: Magnetic resonance cholangiopancreatography diagnosis of choledochal cyst involving the cystic duct: report of three cases.

Yoon, J-H

The British journal of radiology

2010 Volume 84, Issue 997, Page(s) e18–22

Abstract: Here we describe three cases of choledochal cyst involving the cystic duct or isolated dilatation of the cystic duct. All cases were visualised on MR cholangiopancreatography (MRCP) imaging. We report findings of ultrasonography, CT and MRCP. These cases ...

Abstract	Here we describe three cases of choledochal cyst involving the cystic duct or isolated dilatation of the cystic duct. All cases were visualised on MR cholangiopancreatography (MRCP) imaging. We report findings of ultrasonography, CT and MRCP. These cases are extremely rare; nine cases have been reported in the English-language literature. This anomaly was not included in Todani's classifications of choledochal cysts, a system that is accepted worldwide. We think that this variant anomaly will be included in this classification system in the near future.
MeSH term(s)	Adolescent ; Cholangiography/methods ; Choledochal Cyst/diagnosis ; Choledochal Cyst/diagnostic imaging ; Choledochal Cyst/surgery ; Female ; Gallstones/complications ; Humans ; Magnetic Resonance Imaging ; Middle Aged ; Ultrasonography
Language	English
Publishing date	2010-12-20
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2982-8
ISSN	1748-880X ; 0007-1285
ISSN (online)	1748-880X
ISSN	0007-1285
DOI	10.1259/bjr/77844300
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: High-mobility group box 1 protein induces epithelialmesenchymal transition in upper airway epithelial cells.

Min, H J / Choe, J W / Kim, K S / Yoon, J H / Kim, C H

Rhinology

2020 Volume 58, Issue 5, Page(s) 495–505

Abstract: Background: In the treatment of rhinosinusitis, nasal polyps are a major problem, and the epithelial-to-mesenchymal transition (EMT) process is considered pivotal in their development. Although various studies have addressed the role of high mobility ... ...

Abstract	Background: In the treatment of rhinosinusitis, nasal polyps are a major problem, and the epithelial-to-mesenchymal transition (EMT) process is considered pivotal in their development. Although various studies have addressed the role of high mobility group box 1 (HMGB1) nuclear protein in this setting, its impact on EMT has yet to be evaluated. Our aim was the pathogenic mechanism of HMGB1 in EMT and EMT-induced upper respiratory nasal polyps. Methods: We investigated the EMT-related effects of HMGB1 in human nasal epithelial (HNE) cells using western blot analysis, transepithelial-electrical resistance (TEER) testing, wound healing assay, and immunofluorescence. HNE cells were incubated in a low-oxygen environment to evaluate the role of HMGB1 in hypoxia-induced EMT. Further support for our in vitro findings was obtained through murine models. Human nasal polyps and nasal lavage fluid samples were collected for western blotting, immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Results: HMGB1 increased mesenchymal markers and decreased epithelial markers in HNE cells. Hypoxia-induced HMGB1 in turn induced EMT, apparently through RAGE signaling. We verified HMGB1-induced EMT in the upper respiratory epithelium of mice by instilling intranasal HMGB1. In testing of human nasal polyps, HMGB1 and mesenchymal markers were heightened, whereas epithelial markers were reduced, compared with tissue controls. Conclusion: HMGB1 secretion in nasal epithelium may be a major pathogenic factor in upper respiratory EMT, contributing to nasal polyps.
MeSH term(s)	Animals ; Epithelial Cells ; Epithelial-Mesenchymal Transition ; HMGB1 Protein/metabolism ; HMGB1 Protein/physiology ; Humans ; Mice ; Nasal Polyps/metabolism ; Sinusitis/metabolism
Chemical Substances	HMGB1 Protein ; HMGB1 protein, human ; HMGB1 protein, mouse
Language	English
Publishing date	2020-05-30
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	80336-4
ISSN	0300-0729
ISSN	0300-0729
DOI	10.4193/Rhin18.281
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Article: Detection of viable but nonculturable Vibrio parahaemolyticus induced by prolonged cold‐starvation using propidium monoazide real‐time polymerase chain reaction

Yoon, J.‐H / Choi, C / Lee, S.‐Y / Moon, S.‐K / Ryu, B.‐Y

Letters in applied microbiology. 2019 June, v. 68, no. 6

2019

Abstract: Viable but nonculturable (VBNC) Vibrio parahaemolyticus cannot be detected by the standard cultivation‐based methods. In this study, commonly used viability assessment methods were evaluated for the detection of V. parahaemolyticus in a VBNC state. ... ...

Abstract	Viable but nonculturable (VBNC) Vibrio parahaemolyticus cannot be detected by the standard cultivation‐based methods. In this study, commonly used viability assessment methods were evaluated for the detection of V. parahaemolyticus in a VBNC state. Vibrio parahaemolyticus cells exposed to nutrient deficiency at cold temperature were used for epifluorescence microscopy with SYTO9 and propidium iodide (PI) staining and real‐time polymerase chain reaction (qPCR) with propidium monoazide (PMA), and its resuscitative ability was determined by a temperature upshift in freshly prepared artificial sea water (ASW; pH 7) fluids. Viable cells with intact membranes always exceeded 5·0 log CFU per ml in ASW microcosms at 4°C. After 80 days, cycle thresholds for V. parahaemolyticus ATCC 27969 were 16·15–16·69. During cold‐starvation, PMA qPCR selectively excluded DNAs from heat‐killed cells. However, there may be some penetration of PMA into undamaged cells that persisted in ASW for 150 days, as evidenced by their ability to resuscitate from a VBNC state after a temperature upshift (25°C); V. parahaemolyticus ATCC 33844 and V. parahaemolyticus ATCC 27969 were successfully reactivated from a VBNC state in ASW microcosms containing <5% NaCl, following enrichment in ASW medium (pH 7). SIGNIFICANCE AND IMPACT OF THE STUDY: Few studies have evaluated the characteristics of and detection methods for viable but nonculturable (VBNC) Vibrio parahaemolyticus induced by cold‐starvation. Currently, VBNC cells are routinely detected by SYTO9 and propidium iodide double staining. However, viable cell counts might be overestimated by this approach, suggesting that the fluorescence dyes may be ineffective for accurately determining the viability of bacterial cells. We demonstrated that quantitative real‐time polymerase chain reaction with propidium monoazide, which selectively permeates damaged cell membranes, can be used to obtain viable cell counts of V. parahaemolyticus after its evolution to a VBNC state under cold‐starvation conditions.
Keywords	bacteria ; cell membranes ; cell viability ; cold ; fluorescence microscopy ; fluorescent dyes ; nutrient deficiencies ; permeates ; pH ; propidium ; quantitative polymerase chain reaction ; seawater ; sodium chloride ; staining ; temperature ; Vibrio parahaemolyticus
Language	English
Dates of publication	2019-06
Size	p. 537-545.
Publishing place	John Wiley & Sons, Ltd
Document type	Article
Note	JOURNAL ARTICLE
ZDB-ID	632584-1
ISSN	1472-765X ; 0266-8254
ISSN (online)	1472-765X
ISSN	0266-8254
DOI	10.1111/lam.13157
Database	NAL-Catalogue (AGRICOLA)

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