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  1. Article ; Online: Hepatology and the humanities.

    Yoshida, Eric M / Chandok, Natasha

    Canadian liver journal

    2024  Volume 7, Issue 1, Page(s) 1–2

    Language English
    Publishing date 2024-02-26
    Publishing country Canada
    Document type Editorial
    ISSN 2561-4444
    ISSN (online) 2561-4444
    DOI 10.3138/canlivj-2024-0005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Berberine Ursodeoxycholate for the Treatment of Primary Sclerosing Cholangitis: The Search for the Elusive Pharmacologic Holy Grail Will Need to Continue.

    Yoshida, Eric M

    The American journal of gastroenterology

    2022  Volume 117, Issue 11, Page(s) 1762–1763

    Abstract: Abstract: Effective pharmacologic treatment of primary sclerosing cholangitis (PSC) remains elusive. Ursodeoxycholic acid (UDCA) is known to improve liver biochemistry, specifically serum alkaline phosphatase, in patients with PSC but has not been shown ...

    Abstract Abstract: Effective pharmacologic treatment of primary sclerosing cholangitis (PSC) remains elusive. Ursodeoxycholic acid (UDCA) is known to improve liver biochemistry, specifically serum alkaline phosphatase, in patients with PSC but has not been shown to favourably alter the natural history. Similarly, many immunomodulatory medications have been studied for the treatment of PSC, but none has been demonstrated to be of unequivocal benefit. In this issue of the Journal, a pilot study of a ursodeoxycholate berberine salt vs placebo is reported. Although improvement in serum alkaline phosphatase is reported, without a control arm with UDCA monotherapy, it is not possible to determine whether this study drug is beneficial over UDCA by itself. More study in the PSC therapeutic arena is needed.
    MeSH term(s) Humans ; Alkaline Phosphatase ; Berberine/therapeutic use ; Bile Acids and Salts ; Cholagogues and Choleretics/therapeutic use ; Cholangitis, Sclerosing/drug therapy ; Pilot Projects ; Ursodeoxycholic Acid/therapeutic use
    Chemical Substances Alkaline Phosphatase (EC 3.1.3.1) ; Berberine (0I8Y3P32UF) ; Bile Acids and Salts ; Cholagogues and Choleretics ; Ursodeoxycholic Acid (724L30Y2QR)
    Language English
    Publishing date 2022-09-26
    Publishing country United States
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 390122-1
    ISSN 1572-0241 ; 0002-9270
    ISSN (online) 1572-0241
    ISSN 0002-9270
    DOI 10.14309/ajg.0000000000001999
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ui V Zs.36: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: MAESTRO finally plays the music.

    Chandok, Natasha / Yoshida, Eric M

    Canadian liver journal

    2024  Volume 7, Issue 2, Page(s) 255–256

    Language English
    Publishing date 2024-05-08
    Publishing country Canada
    Document type Journal Article
    ISSN 2561-4444
    ISSN (online) 2561-4444
    DOI 10.3138/canlivj-2024-0013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Five years after….

    Chandok, Natasha / Yoshida, Eric M

    Canadian liver journal

    2023  Volume 6, Issue 1, Page(s) 1

    Language English
    Publishing date 2023-02-28
    Publishing country Canada
    Document type Editorial
    ISSN 2561-4444
    ISSN (online) 2561-4444
    DOI 10.3138/canlivj-2022-12-12
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The untitled editorial.

    Yoshida, Eric M / Chandok, Natasha

    Canadian liver journal

    2023  Volume 6, Issue 4, Page(s) 373–374

    Language English
    Publishing date 2023-12-20
    Publishing country Canada
    Document type Editorial
    ISSN 2561-4444
    ISSN (online) 2561-4444
    DOI 10.3138/canlivj-2023-0029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Once upon a time in Canadian hepatology, we were accepted into PubMed….

    Yoshida, Eric M / Chandok, Natasha

    Canadian liver journal

    2022  Volume 5, Issue 3, Page(s) 327–328

    Language English
    Publishing date 2022-08-16
    Publishing country Canada
    Document type Editorial
    ISSN 2561-4444
    ISSN (online) 2561-4444
    DOI 10.3138/canlivj-2022-0024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Ukraine strong.

    Yoshida, Eric M / Chandok, Natasha

    Canadian liver journal

    2022  Volume 5, Issue 2, Page(s) 101–102

    Language English
    Publishing date 2022-05-09
    Publishing country Canada
    Document type Editorial
    ISSN 2561-4444
    ISSN (online) 2561-4444
    DOI 10.3138/canlivj-2022-0008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Hepatology in the time of COVID-19: Part 2.

    Yoshida, Eric M / Chandok, Natasha

    Canadian liver journal

    2022  Volume 5, Issue 4, Page(s) 437–438

    Language English
    Publishing date 2022-11-07
    Publishing country Canada
    Document type Editorial
    ISSN 2561-4444
    ISSN (online) 2561-4444
    DOI 10.3138/canlivj-2022-09-04
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: The acute hepatitis outbreak in children in 2022: The story so far.

    Chandok, Natasha / Yoshida, Eric M

    Canadian liver journal

    2022  Volume 5, Issue 4, Page(s) 439–440

    Language English
    Publishing date 2022-11-07
    Publishing country Canada
    Document type Editorial
    ISSN 2561-4444
    ISSN (online) 2561-4444
    DOI 10.3138/canlivj-2022-09-05
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Order via subito

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  10. Article ; Online: Review of liver transplantation candidacy and outcomes among patients who use cannabis: Is it time for a change in policy?

    Yau, Man Ting Kristina / Hussaini, Trana / Yoshida, Eric M

    Canadian liver journal

    2023  Volume 6, Issue 2, Page(s) 269–277

    Abstract: Background: Recreational cannabis was legalized in Canada in 2018. A controversial contraindication for liver transplantation is cannabis. There is currently no consensus regarding cannabis use in liver transplant candidates. We aim to investigate liver ...

    Abstract Background: Recreational cannabis was legalized in Canada in 2018. A controversial contraindication for liver transplantation is cannabis. There is currently no consensus regarding cannabis use in liver transplant candidates. We aim to investigate liver transplantation candidacy and outcomes among cannabis users.
    Methods: English peer-reviewed studies on PubMed and Google Scholar were searched on September 9, 2022, using keywords including "cannabis," "liver transplantation," and their synonyms. Titles and abstracts were screened, followed by full texts. Reference lists were reviewed. Studies that investigated liver transplantation candidacy and outcomes among cannabis users were included.
    Results: The proportion of patients listed for liver transplantation was significantly less among cannabis users than among non-users. Time to listing was longer for cannabis users than non-users. The incidence of delisting was similar. There is an inconsistency between transplant centres regarding transplantation candidacy for cannabis users. While only 14% of Canadian centres had a policy in place and preferred candidates to abstain or decrease cannabis use before transplantation, a third of Canadian centres rejected cannabis users. Observational studies failed to demonstrate significant differences in patient survival between pre-transplantation cannabis users and non-users. However, self-reported mental health ratings were worse in post-transplantation cannabis users than in non-users and former users.
    Conclusions: Current observational data do not support a link between cannabis use and poor patient survival post-transplantation. However, high-quality prospective studies are needed to better elucidate the impact of cannabis use on liver transplantation outcomes. Liver transplant candidacy should be evaluated through a multidisciplinary and comprehensive approach considering all relevant psychosocial factors.
    Language English
    Publishing date 2023-07-26
    Publishing country Canada
    Document type Journal Article ; Review
    ISSN 2561-4444
    ISSN (online) 2561-4444
    DOI 10.3138/canlivj-2022-0038
    Database MEDical Literature Analysis and Retrieval System OnLINE

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